COOH-terminal extended recombinant amphiregulin with bioactivity comparable with naturally derived growth factor

Journal of Biological Chemistry

Volumn 271, Issue 30, 1996, Pages 17927-17931

  Thompson, Stewart A ^a   Harris, Angela ^b   Hoang, Danee ^a   Ferrer, Micheal ^a   Johnson, Gibbes R ^c  

^a BAYER AG   (Germany)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; GROWTH FACTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL SURVIVAL; DRUG ACTIVITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; STEM CELL;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GLYCOPROTEINS; GROWTH SUBSTANCES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MICE; MITOGENS; MOLECULAR SEQUENCE DATA; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI; MINK CELL FOCUS-FORMING VIRUS;

EID: 0029943486     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.30.17927     Document Type: Article

References (42)

1. Carpenter, G., and Cohen, S. (1990) J. Biol. Chem. 265, 7709-7712
2. Derynck, R., Roberts, A. B., Winkler, M. E., Chen, E. Y., and Goeddel, D. V. (1984) Cell 38, 287-297
3. Shoyab, M., Plowman, G. D., McDonald, V. L., Bradley, J. G., and Todaro, G. J. (1989) Science 243, 1074-1076
4. Higashiyama, S., Abraham, J. A., Miller, J., Fiddles, J. C., and Klagsbrun, M. (1991) Science 251, 936-939
5. Shing, Y., Christofori, G., Hanahan, D., Ono, Y., Sasada, R., Igarashi, K., and Folkman, J. (1993) Science 259, 1604-1607
6. Toyoda, H., Komurasaki, T., Uchida, D., Takayama, Y., Isobe, T., Okuyama, T., and Hanada, K. (1995) J. Biol. Chem. 270, 7495-7500
7. Shoyab, M., McDonald, V. L., Bradley, J. G., and Todaro, G. J. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 6528-6532
8. Cook, P. W., Mattox, P. A., Keeble, W. W., Pittelkow, M. R., Plowman, G. D., Shoyab, M., Adelman, J. P., and Shipley, G. D. (1991) Mol. Cell. Biol. 11, 2547-2557
9. Johnson, G. R., Saeki, T., Auersperg, N., Gordon, A. W., Shoyab, M., Salomon, D. S., and Stromberg, K. (1991) Biochem. Biophys. Res. Commun. 180, 481-488
10. Johnson, G. R., Saeki, T., Gordon, A. W., Shoyab, M., Salomon, D. S., and Stromberg, K. (1992) J. Cell Biol. 118, 741-751
11. Johnson, G. R., Kannan, B., Shoyab, M., and Stromborg, K. (1993) J. Biol. Chem. 268, 2924-2931
12. Johnson, G. R., Prigent, S. A., Gullick, W. J., and Stromberg, K. (1993) J. Biol. Chem. 268, 18835-18843
13. Johnson, G. R., and Wong, L. (1994) J. Biol. Chem. 269, 27149-27154
14. Normanno, N., Selvam, M. P., Qi, C.-F., Saeki, T., Johnson, G. Kim, N., Ciardiello, F., Shoyab, M., Plowman, G., Brandt, R., Todaro, G., and Salomon, D. S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2790-2794
15. Lysiak, J. J., Johnson, G. R., and Lala, P. K. (1995) Placenta 16, 359-366
16. Yokohama, M., Ebert, M., Funatomi, H., Friess, H., Buchler, M. W., Johnson, G. R., and Korc, M. (1995) Int. J. Oncol. 6, 625-631
17. Higashiyama, S., Abraham, J. A., and Klagsbrun, M. (1993) J. Cell Biol. 122, 933-940
18. Thompson, S. A., Higashiyama, S., Wood, K., Pollitt, N. S., Damm, D., McEnroe, G., Garrick, B., Ashton, N., Lau, K., Hancock, N., Klagsbrun, M., and Abraham, J. A. (1994) J. Biol. Chem. 269, 2541-2549
19. Johnson, G. R. (1995) Trends Glycosci. Glycotech. 7, 261-271
20. Plowman, G. D., Green, J. M., McDonald, V. L., Neubauer, M. G., Disteche, C. M., Todaro, G. J., and Shoyab, M. (1990) Mol. Cell. Biol. 10, 1969-1981
21. Saeki, T., Stromberg, K., Qi, C.-F., Gullick, W. J., Tahara, E., Normanno, N., Ciardiello, F., Kenney, N., Johnson, G. R., and Salomon, D. S. (1992) Cancer Res. 52, 3467-3473
22. Kitadai, Y., Yasui, W., Yokozaki, H., Kuniyasu, H., Ayhan, A., Haruma, K., Kajiyama, G., Johnson, G. R., and Tahara, E. (1993) Jpn. J. Cancer Res. 84, 879-884
23. Ebert, M., Yokoyama, M., Kobrin, M. S., Friess, H., Lopez, M. E., Buchler, M. W., Johnson, G. R., and Korc, M. (1994) Cancer Res. 54, 3959-3962
24. Qi, C.-F., Liscia, D. S., Normanno, N., Merlo, G., Johnson, G. R., Gullick, W. J., Ciardiello, F., Saeki, T., Brandt, R., Kim, N., Kenney, N., and Salomon, D. S. (1994) Br. J. Cancer 69, 903-910
25. Martinez-Lacaci, I., Saceda, M., Plowman, G. D., Johnson, G. R., Normanno, N., Salomon, D. S., and Dickson, R. B. (1995) Endocrinology 136, 3983-3992
26. Normanno, N., Qi, C.-F., Gullick, W. J., Persico, G., Yarden, Y., Wen, D., Plowman, G., Kenney, N., Johnson, G., Kim, N., Brandt, R., Martinez- Lacaci, I., Dickson, R. B., and Salomon, D. S. (1993) Int. J. Oncol. 2, 903-911
27. Sehgal, I., Bailey, J., Hitzemann, K., Pittelkow, M. R., and Maihle, N. J. (1994) Mol. Biol. Cell 5, 339-347
28. Barnard, J. A., Graves-Deal, R., Pittelkow, M. R., DuBois, R., Cook, P., Ramsey, G. W., Bishop, P. R., Damstrup, L., and Coffey, R. J. (1994) J. Biol. Chem. 269, 22817-22822
29. Saeki, T., Salomon, D., Normanno, N., Johnson, G. R., Gullick, W. J., Mandai, K., Moriwaki, S., Takashima, S., Kuniyasu, M., Tahara, E., Kawami, H., Nishiyama, M., and Toge, T. (1994) Int. J. Oncol. 5, 215-223
30. Cook, P. W., Pittelkow, M. H., Keeble, W. W., Graves-Deal, R., Coffey, J., and Shipley, G. D. (1992) Cancer Res. 52, 3224-3227
31. Li, S., Plowman, G. D., Buckley, S. D., and Shipley, G. D. (1992) J. Cell. Physiol. 153, 103-111
32. Kenney, N., Johnson, G., Selvam, M. P., Kim, N., Qi, C.-F., Saeki, T., Brandt, R., Wallace-Jones, B., Ciardiello, F., Shoyab, M., Plowman, G., Day, A., Salomon, D. S., and Normanno, N. (1993) Mol. Cell. Differ. 1, 163-184
33. Woodworth, C. D., McMullen, E., Iglesias, M., and Plowman, G. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2840-2844
34. Kenney, N. J., Huang, R.-P., Johnson, G. R., Wu, J.-X., Okamura, D., Matheny, W., Kordon, E., Gullick, W. J., Plowman, G., Smith, G. H., Salomon, D. S., and Adamson, E. D. (1995) Mol. Reprod. Dev. 41, 277-286
35. Adam, R., Drummond, D. R., Solic, N., Holt, S. J., Sharma, R. F., Chamberlin, S. G., and Davies, D. E. (1995) Biochim. Biophys. Acta 1226, 83-90
36. Chen, P., Gupta, K., and Wells, A. (1994) J. Cell Biol. 124, 547-555
37. Spear, K., and Sliwkowski, M. (1991) Techniques in Protein Chemistry II, pp. 233-240, Academic Press, San Diego, CA
38. Vlahos, C., Wilhelm, O., Hassel, T., Jaskunas, S., and Bang, N. (1991) J. Biol. Chem. 266, 10070-10072
39. Marti, T., Rosselet, T., Titani, K., and Walsh, K. (1987) Biochemistry 26, 8099-8109
40. Haniu, M., Rohde, M., and Kenney, W. (1993) Biochemistry 32, 2431-2437
41. Carpenter, G., Lembach, K., Morrison, M., and Cohen, S. (1975) J. Biol. Chem. 250, 4297-4304
42. Holmes, W., Sliwkowski, M., Akita, R., Henzel, W., Lee, J., Park, J., Yansura, D., Abadi, N., Raab, H., Lewis, G., Shepard, H., Kuang, W.-J., Wood, W., Goeddel, D., and Vandlen, R. (1992) Science 256, 1205-1210