Analysis of the forces which stabilize the active conformation of urokinase-type plasminogen activator

Biochemistry

Volumn 37, Issue 9, 1998, Pages 2935-2940

  Sun, Ziyong ^a,b   Liu, Bei Fang ^a   Chen, Yuhong ^a   Gurewich, Victor ^b   Zhu, Dexu ^a   Liu, Jian Ning ^a,b,c  

^a NANJING UNIVERSITY   (China)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Deaconess Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; PLASMINOGEN ACTIVATOR; SERINE PROTEINASE; UROKINASE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ASPARTIC ACID; CATALYSIS; ENZYME STABILITY; HYDROLYSIS; ISOLEUCINE; KINETICS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; URINARY PLASMINOGEN ACTIVATOR;

EID: 0032478193     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971702c     Document Type: Article

References (38)

1. Birktoft, J., Kraut, J., and Freer, S. (1976) Biochemistry 15, 4481-4485.
2. Kossiakoff, A. A., Chambers, J. L., Kay, L. M., and Stroud, R. M. (1977) Biochemistry 16, 654-664.
3. Huber, H., and Bode, W. (1978) Acc. Chem. Res. 11, 114-122.
4. Alber, T. (1989) Annu. Rev. Biochem. 58, 765-798.
5. Dill, K. A. (1990) Biochemistry 29, 7133-7155.
6. Gertler, A., Walsh, K. A., and Neurath, H. (1974) Biochemistry 13, 1302-1310.
7. Antonini, E., Ascenzi, P., Bolognesi, M., Guarneri, M., Menegatti, E., and Amiconi, G. (1984) Mol. Cell. Biochem. 60, 163-181.
8. Fersht. A. R. (1972) J. Mol. Biol. 64, 497-509.
9. Hedstrom L., Lin, T.-Y., and Fast, W. (1996) Biochemistry, 35, 4515-4523.
10. Collen, D., Zamarron, C., Lijnen, H. R., and Hoylaerts, M. (1986) J. Biol. Chem. 261, 1259-1266.
11. Pannell, R., and Gurewich, V. (1986) Blood 67, 1215-1223.
12. Pannell, R., and Gurewich, V. (1987) Blood 69, 22-26.
13. Petersen, L. D., Lund, L. R., Dano, K., Nielsen, L. S., and Skriver, L. (1988) J. Biol. Chem. 263, 11189-11195.
14. Lijnen, H. R., Van Hoef, B., Nelles, L., and Collen, D. (1990) J. Biol. Chem. 265, 5232-5236.
15. Liu, J.-N., Pannell, R., and Gurewich, V. (1992) J. Biol. Chem. 267, 15289-15292.
16. Liu, J.-N., and Gurewich, V. (1992) Biochemistry 31, 6311-6317.
17. Liu, J.-N., and Gurewich, V. (1993) Blood 81, 980-987.
18. Liu, J.-N., and Gurewich, V. (1995) J. Biol. Chem. 270, 8408-8410.
19. Manchanda, N., and Schwartzs, B. S. (1991) J. Biol. Chem. 266, 14580-14584.
20. Manchanda, N., and Schwartzs, B. S. (1995) J. Biol. Chem. 270, 20032-20035.
21. Higazi, A. A.-R., Cohen, R. L., Henkin, J., Kniss, D., Schwartz B. S., Cines, D. B. (1995) J. Biol. Chem. 270, 17375-17380.
22. Wang, J., Mazar, A., Quan, N., Schneider, A., and Henkin, J. (1997) Eur. J. Biochem. 247, 256-261.
23. Liu, J.-N., Tang, W., Sun, Z.-Y., Kung, W., Pannell, R., Sarmientos, P., and Gurewich, V. (1996) Biochemistry 35, 14070-14076.
24. Sun, Z., Jiang, Y., Ma, Z., Wu, H., Liu, B., Xu, Y., Tang, W., Chen, Y., Li, C., Zhu, DX., Gurewich, V., Liu, J.-N. (1997) J. Biol. Chem. 272, 23818-23823.
25. Liu, B.-F., Sun, Z., Wu, H., Zhu, DX., Liu, J.-N. (1997) Thromb. Haemostasis (abstr), Supplement: 751.
26. Madison, E. L., Kobe, A., Gething, M.-J., Sambrook, J. F., and Goldsmith, E. J. (1993) Science 262, 419-421.
27. Peterson, L. C., Boel, E., Johannessen, M., and Foster, D. (1990) Biochemistry 29, 3451-3457.
28. Tachias, K., and Madison, E. L. (1996) J. Biol. Chem. 271, 28749-28752.
29. Nienaber, V. L., Young, S. L., Birktoft, J. J., Higgins, D. L., and Berliner, L. J. (1992) Biochemistry 31, 3852-3861.
30. Lamba, D., Bauer, M., Huber, R., Fischer, S., Rudolph, R., Kohnert, U., and Bode, W. (1996) J. Mol. Biol. 258, 117-135.
31. Tachias, K., and Madison, E. L. (1997) J. Biol. Chem. 272, 28-31.
32. Verde, P., Stoppelli, M. P., Galeffi, P., Di Nocera, P., and Blasi, F. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 4727-4731.
33. Orini, G., Brandazza, A., Sarmientos, P., Molinari, A., Lansen, J., and Cauet, G. (1991) Eur. J. Biochem. 195, 691-697.
34. Winkler, M. E., and Blaber, M. (1986) Biochemistry 25, 4041-4045.
35. Eisenberg, D., Schwartz, E., Komaromy, M., and Wall, R. (1984) J. Mol. Biol. 179, 125-142.
36. Tate, K. M., Higgins, D. L., Holmes, W. E., Winkler, M. E., Heyneker, H. L., and Vehar, G. A. (1987) Biochemistry 26, 338-343.
37. Rijken, D. C., Hoylaerts, M., and Collen, D. (1982) J. Biol. Chem. 257, 2920-2925.
38. Liu, J.-N., and Gurewich, V. (1991) J. Clin. Invest. 88, 2012-2017.