Converting tissue-type plasminogen activator into a zymogen

Journal of Biological Chemistry

Volumn 271, Issue 46, 1996, Pages 28749-28752

  Tachias, Kathy ^a   Madison, Edwin L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; COS CELLS; ENZYME PRECURSORS; MUTAGENESIS, SITE-DIRECTED; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0029800327     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.46.28749     Document Type: Article

References (59)

1. Neurath, H. (1984) Science 224, 350-357
2. Neurath, H. (1989) Trends Biochem, Sci. 14, 268-271
3. Neurath, H. (1986) J. Cell. Biochem. 32, 35-49
4. Mann, K. G., and Lorand, L. (1993) Methods Enzymol. 223, 145-288
5. High, K. A., and Roberts, H. R. (1995) Molecular Basis of Thrombosis and Hemostasis, Marcel Dekker, New York, NY
6. Lijnen, H. R., and Collen, D. (1988) Enzyme 40, 90-96
7. Collen, D., and Lijnen, H. R. (1992) in The Heart and Cardiovascular System (Fozzard, H. A., ed) 2nd Ed., pp. 275-294, Raven Press, New York
8. Spraggon, G., Phillips, C., Nowak, U. K., Ponting, C. P., Saunders, D., Dobson, C. M., Stuart, D. I., and Jones, E. Y. (1995) Structure 3, 681-691
9. Lamba, B., Bauer, M., Huber, R., Fischer, S., Rudolph, R., Kohnert, U., and Bode, W. (1996) J. Mol. Biol. 258, 117-135
10. Boose, J. A., Kuismanen, E., Gerard, R., Sambrook, J., and Gething, M.-J. (1989) Biochemistry 28, 635-643
11. Ranby, M., Bergsdorf, N., and Nilsson, T. (1982) Thromb, Res. 27, 175-183
12. Tate, K. M., Higgins, D. L., Holmes, W. E., Winkler, M. E., Heyneker, H. L., and Vehar, G. A. (1987) Biochemistry 26, 338-343
13. Madison, E. L., Kobe, A., Gething, M.-J., Sambrook, J. F., and Goldsmith, E. J. (1993) Science 262, 419-421
14. Robinson, N. C., Neurath, H., and Walsh, K. A. (1973) Biochemistry 12, 420-426
15. Gertler, A., Walsh, K. A., and Neurath, H. (1974) Biochemistry 13, 1302-1310
16. Silverberg, M., and Kaplan, A. P. (1982) Blood 60, 64
17. Lijnen, H. R., Van Hoef, B., Nelles, L., and Collen, D. (1990) J. Biol. Chem. 265, 5232-5236
18. Tachias, K., and Madison, E. L. (1995) J. Biol. Chem. 270, 18319-18322
19. Neinaber, V. L., Young, S. L., Birktoft, J. J., Higgins, D. L., and Berliner, L. J. (1992) Biochemistry 31, 3852-3861
20. Zoller, M. J., and Smith, M. (1982) Nucleic Acids Res. 10, 6487
21. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 488-492
22. Madison, E. L., Goldsmith, E. J., Gerard, R. D., Gething, M. J., and Sambrook, J. F. (1989) Nature 339, 721-724
23. Madison, E. L., Goldsmith, E. J., Gerard, R. D., Gething, M. J., Sambrook, J. F., and Bassel-Duby, R. S. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3530-3533
24. Madison, E. L., Goldsmith, E. J., Gething, M. J., Sambrook, J. F., and Gerard, R. D. (1990) J. Biol. Chem. 265, 21423-21426
25. Strandberg, L., and Madison, E. L. (1995) J. Biol. Chem. 270, 23444-23449
26. Smith, J. W., Tachias, K., and Madison, E. L. (1995) J. Biol. Chem. 270, 30486-30490
27. Holmes, W. E., Lijnen, H. R., and Colien, D. (1987) Biochemistry 26, 5133-5140
28. Beatty, K., Bieth, J., and Travis, J. (1980) J. Biol. Chem. 255, 3931-3934
29. Lijnen, H. R., Van Hoef, B., and Collen, D. (1990) Thromb. Res. 57, Suppl. X, 45-54
30. Collen, D., and Lijnen, H. R. (1991) Blood 78, 3114-3124
31. Madison, E. L. (1994) Fibrinolysis 8, 221-236
32. Lijnen, H. R., and Collen, D. (1991) Thromb. Haemostasis 66, 88-110
33. Collen, D., and Lijnen, H. R. (1995) Thromb. Haemostasis 74, 167-171
34. Petersen, L. C., Johannessen, M., Foster, D., Kumar, A., and Mulvihill, E. (1988) Biochim. Biophys. Acta 952, 245-254
35. Summaria, L., Arzadon, L., Bernabe, P., and Robbins, K. C. (1974) J. Biol. Chem. 249, 4760-4769
36. Reddy, K. N. N., and Markus, G. (1972) J. Biol. Chem. 247, 1683-1691
37. Reddy, K. N. N. (1988) Enzyme 40, 79-89
38. Schick, L. A., and Castellino, F. J. (1973) Biochemistry 12, 4315-4320
39. Davidson, D. J., Higgins, D. L., and Castellino, F. J. (1990) Biochemistry 29, 3585-3590
40. Lijnen, H. R., DeCock, F., Matsuo, O., and Collen, D. (1992) Fibrinolysis 6, 33-37
41. Hemker, H. C., Bas, B. M., and Muller, A. D. (1975) Biochim. Biophys. Acta 379, 180-188
42. Hendrix, H., Lindhout, T., Mertens, K., Engels, W., and Hemker, H. C. (1983) J. Biol. Chem. 258, 3637-3644
43. Huber, R., and Bode, W. (1978) Acc. Chem. Res. 11, 114-122
44. Freer, S. T., Kraut, J., Robertus, J. D., Wright, H. T., and Xuong, N. H. (1970) Biochemistry 9, 1997-2009
45. Fehlhammer, H., Bode, W., and Huber, R. (1977) J. Mol. Biol. 111, 415-438
46. Wang, D., Bode, W., and Huber, R. (1985) J. Mol. Biol. 185, 595-624
47. Kossiakoff, A. A., Chambers, J. L., Kay, L. M., and Stroud, R. M. (1977) Biochemistry 16, 654-664
48. Steitz, T. A., Henderson, R., and Blow, D. M. (1969) Journal Mol. Biol. 46, 337-348
49. Matthews, B. W., Sigler, P. B., Henderson, R., and Blow, D. M. (1967) Nature 214, 652-656
50. Sigler, P. B., Blow, D. M., Matthews, B. W., and Henderson, R. (1968) J. Mol. Biol. 35, 143
51. Blow, D. M., Birktoft, J. J., and Hartley, B. S. (1969) Nature 221, 337
52. Stroud, R. M., Kay, L. M., and Dickerson, R. E. (1974) J. Mol. Biol. 83, 185-208
53. Bode, W., and Schwager, P. (1975) J. Mol. Biol. 98, 693-717
54. Miles, L. A., and Plow, E. F. (1985) J. Biol. Chem. 260, 4303-4311
55. Huber, R., and Bennett, W. S., Jr. (1983) Biopolymers 22, 261-279
56. Kerr, M. A., Walsh, K. A., and Neurath, H. (1976) Biochemistry 15, 5566-5570
57. Bode, W., and Huber, R. (1976) FEBS Lett. 68, 231-236
58. Bode, W., Schwager, P., and Huber, R. (1978) J. Mol. Biol. 118, 99-112
59. Bode, W. (1979) J. Mol. Biol. 127, 357-374