메뉴 건너뛰기




Volumn 79, Issue 4, 1998, Pages 253-259

Molecular genetics of Wiedemann-Beckwith syndrome

Author keywords

Genomic imprinting; IGF2; Overgrowth syndromes; p57(KIP2); Wiedemann Beckwith syndrome

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; BECKWITH WIEDEMANN SYNDROME; CHROMOSOME 11P; CONFERENCE PAPER; GENETIC DISORDER; GENOME IMPRINTING; GROWTH DISORDER; GROWTH REGULATION; MULTIPLE MALFORMATION SYNDROME; NONHUMAN; PRIORITY JOURNAL;

EID: 0032475940     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19981002)79:4<253::AID-AJMG5>3.0.CO;2-N     Document Type: Conference Paper
Times cited : (125)

References (76)
  • 1
    • 0030846298 scopus 로고    scopus 로고
    • Tying it all together: Epigenetics, genetics, cell cycle, and cancer
    • Baylin SB (1997): Tying it all together: Epigenetics, genetics, cell cycle, and cancer. Science 277:1948-1949.
    • (1997) Science , vol.277 , pp. 1948-1949
    • Baylin, S.B.1
  • 2
    • 0000077851 scopus 로고
    • Macroglossia, omphalocele, adrenal cytomegaly, gigantism, and hyperplastic visceromegaly
    • Beckwith J (1969): Macroglossia, omphalocele, adrenal cytomegaly, gigantism, and hyperplastic visceromegaly. Birth Defects: Original Articles Series 5:188-196.
    • (1969) Birth Defects: Original Articles Series , vol.5 , pp. 188-196
    • Beckwith, J.1
  • 3
    • 0019005172 scopus 로고
    • Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling
    • Berry AC, Belton EM, Chantler C (1980): Monozygotic twins discordant for Wiedemann-Beckwith syndrome and the implications for genetic counselling. J Med Genet 17:136-8.
    • (1980) J Med Genet , vol.17 , pp. 136-138
    • Berry, A.C.1    Belton, E.M.2    Chantler, C.3
  • 5
    • 0029806141 scopus 로고    scopus 로고
    • Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway
    • Brown KW, Villar AJ, Bickmore W, Clayton-Smith J, Catchpoole D, Maher ER, Reik W (1996): Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathway. Hum Mol Genet 5:2027-2032.
    • (1996) Hum Mol Genet , vol.5 , pp. 2027-2032
    • Brown, K.W.1    Villar, A.J.2    Bickmore, W.3    Clayton-Smith, J.4    Catchpoole, D.5    Maher, E.R.6    Reik, W.7
  • 6
    • 0028939902 scopus 로고
    • Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15
    • Buiting K, Saitoh S, Gross S, Dittrich B, Schwartz S, Nicholls R, Horsthemke B (1995): Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15. Nat Genet 9:395-400.
    • (1995) Nat Genet , vol.9 , pp. 395-400
    • Buiting, K.1    Saitoh, S.2    Gross, S.3    Dittrich, B.4    Schwartz, S.5    Nicholls, R.6    Horsthemke, B.7
  • 7
    • 0007665444 scopus 로고
    • A reassessment of Beckwith-Wiedemann syndrome (WBS)
    • Carlin M, Escobar L, Ward R, Wielgus T (1990): A reassessment of Beckwith-Wiedemann syndrome (WBS). Am J Hum Genet 47 (Suppl):A50.
    • (1990) Am J Hum Genet , vol.47 , Issue.SUPPL.
    • Carlin, M.1    Escobar, L.2    Ward, R.3    Wielgus, T.4
  • 9
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara TM, Efstratiadis A, Robertson EJ (1990): A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345:78-80.
    • (1990) Nature , vol.345 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 11
    • 0030053512 scopus 로고    scopus 로고
    • High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas: Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19
    • Douc-Rasy S, Barrois M, Fogel S, Ahomadegbe JC, Stehelin D, Coll J, Riou G (1996): High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas: Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19. Oncogene 12:423-430.
    • (1996) Oncogene , vol.12 , pp. 423-430
    • Douc-Rasy, S.1    Barrois, M.2    Fogel, S.3    Ahomadegbe, J.C.4    Stehelin, D.5    Coll, J.6    Riou, G.7
  • 12
    • 0030660180 scopus 로고    scopus 로고
    • Mouse mutant embryos overexpressing IF-11 exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes
    • Eggenschwiler J, Ludwig T, Fisher P, Leighton PA, Tilghman SM, Efstratiadis A (1997): Mouse mutant embryos overexpressing IF-11 exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev 11:3128-3142.
    • (1997) Genes Dev , vol.11 , pp. 3128-3142
    • Eggenschwiler, J.1    Ludwig, T.2    Fisher, P.3    Leighton, P.A.4    Tilghman, S.M.5    Efstratiadis, A.6
  • 13
    • 0028006662 scopus 로고
    • Parental imprinting and the IGF2 gene
    • Ekstrom TJ (1994): Parental imprinting and the IGF2 gene. Horm Res 42:176-181.
    • (1994) Horm Res , vol.42 , pp. 176-181
    • Ekstrom, T.J.1
  • 14
    • 0031014601 scopus 로고    scopus 로고
    • A 5′ differentially methylated sequence and the 3' flanking region are necessary for H19 transgene imprinting
    • Elson DA, Bartolomei MS (1997): A 5′ differentially methylated sequence and the 3' flanking region are necessary for H19 transgene imprinting. Mol Cell Biol 17:309-317.
    • (1997) Mol Cell Biol , vol.17 , pp. 309-317
    • Elson, D.A.1    Bartolomei, M.S.2
  • 21
    • 0031001346 scopus 로고    scopus 로고
    • Xist has properties of the X-chromosome inactivation centre
    • Herzing L, Romer J, Horn J, Ashworth A (1997): Xist has properties of the X-chromosome inactivation centre. Nat Genet 386:272-275.
    • (1997) Nat Genet , vol.386 , pp. 272-275
    • Herzing, L.1    Romer, J.2    Horn, J.3    Ashworth, A.4
  • 23
    • 0015295131 scopus 로고
    • Mutation and cancer: A model for Wilms' tumor of the kidney
    • Knudson AG, Strong LC (1972): Mutation and cancer: A model for Wilms' tumor of the kidney. J Natl Cancer Inst 48:313-324.
    • (1972) J Natl Cancer Inst , vol.48 , pp. 313-324
    • Knudson, A.G.1    Strong, L.C.2
  • 25
    • 0028575985 scopus 로고
    • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
    • Lau MM, Stewart CE, Liu Z, Bhatt H, Rotwein P, Stewart CL (1994): Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev 8: 2953-2963.
    • (1994) Genes Dev , vol.8 , pp. 2953-2963
    • Lau, M.M.1    Stewart, C.E.2    Liu, Z.3    Bhatt, H.4    Rotwein, P.5    Stewart, C.L.6
  • 26
    • 0030895047 scopus 로고    scopus 로고
    • Long-range cis effects of ectopic X-inactivation centres on a mouse autosome
    • Lee J, Jaenisch R (1997): Long-range cis effects of ectopic X-inactivation centres on a mouse autosome. Nat Genet 386:275-279.
    • (1997) Nat Genet , vol.386 , pp. 275-279
    • Lee, J.1    Jaenisch, R.2
  • 28
    • 0031046285 scopus 로고    scopus 로고
    • Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements
    • Lee MP, Hu RJ, Johnson LA, Feinberg AP (1997b): Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements. Nat Genet 15: 181-185.
    • (1997) Nat Genet , vol.15 , pp. 181-185
    • Lee, M.P.1    Hu, R.J.2    Johnson, L.A.3    Feinberg, A.P.4
  • 32
    • 0029122489 scopus 로고
    • Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: Uncoupling of IGF2 and H19 imprinting
    • Li X, Adam G, Cui H, Sandstedt B, Ohlsson R, Ekstrom TJ (1995): Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: Uncoupling of IGF2 and H19 imprinting. Oncogene 11:221-229.
    • (1995) Oncogene , vol.11 , pp. 221-229
    • Li, X.1    Adam, G.2    Cui, H.3    Sandstedt, B.4    Ohlsson, R.5    Ekstrom, T.J.6
  • 33
    • 0029670454 scopus 로고    scopus 로고
    • Expression levels of the insulin-like growth factor-II gene (IGF2) in the human liver: Developmental relationships of the four promoters
    • Li X, Cui H, Sandstedt B, Nordlinder H, Larsson E, Ekstrom TJ (1996): Expression levels of the insulin-like growth factor-II gene (IGF2) in the human liver: Developmental relationships of the four promoters. J Endocrinol 149:117-124.
    • (1996) J Endocrinol , vol.149 , pp. 117-124
    • Li, X.1    Cui, H.2    Sandstedt, B.3    Nordlinder, H.4    Larsson, E.5    Ekstrom, T.J.6
  • 35
    • 0023748884 scopus 로고
    • Absence of detectable chromosomal and molecular abnormalities in monozygotic twins discordant for the Wiedemann-Beckwith syndrome
    • Litz CE, Taylor KA, Qiu JS, Pescovitz OH, de Martinville B (1988): Absence of detectable chromosomal and molecular abnormalities in monozygotic twins discordant for the Wiedemann-Beckwith syndrome. Am J Med Genet 30:821-833.
    • (1988) Am J Med Genet , vol.30 , pp. 821-833
    • Litz, C.E.1    Taylor, K.A.2    Qiu, J.S.3    Pescovitz, O.H.4    De Martinville, B.5
  • 36
    • 0030950759 scopus 로고    scopus 로고
    • An imprinting element from the mouse H19 locus functions as a silencer in Drosophila
    • Lyko F, Brenton JD, Surani MA, Paro R (1997): An imprinting element from the mouse H19 locus functions as a silencer in Drosophila. Nat Genet 16:171-173.
    • (1997) Nat Genet , vol.16 , pp. 171-173
    • Lyko, F.1    Brenton, J.D.2    Surani, M.A.3    Paro, R.4
  • 37
    • 0024212964 scopus 로고
    • Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumors
    • Mannens M (1988): Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumors. Hum Genet 81:41-48.
    • (1988) Hum Genet , vol.81 , pp. 41-48
    • Mannens, M.1
  • 39
    • 0029939816 scopus 로고    scopus 로고
    • Somatic overgrowth associated with overexpression of insulin-like growth factor II
    • Morison IM, Becroft DM, Taniguchi T, Woods CG, Reeve AE (1996): Somatic overgrowth associated with overexpression of insulin-like growth factor II. Nat Med 2:311-316.
    • (1996) Nat Med , vol.2 , pp. 311-316
    • Morison, I.M.1    Becroft, D.M.2    Taniguchi, T.3    Woods, C.G.4    Reeve, A.E.5
  • 40
    • 0026559276 scopus 로고
    • Beckwith-Wiedemann syndrome: A demonstration of the mechanisms responsible for the excess of transmitting females
    • Moutou C, Junien C, Henry I, Bonaïti-Pellié C (1992): Beckwith-Wiedemann syndrome: A demonstration of the mechanisms responsible for the excess of transmitting females [see comments]. J Med Genet 29:217-220.
    • (1992) J Med Genet , vol.29 , pp. 217-220
    • Moutou, C.1    Junien, C.2    Henry, I.3    Bonaïti-Pellié, C.4
  • 41
    • 0029742296 scopus 로고    scopus 로고
    • Genomic imprinting: Significance in development and diseases and the molecular mechanisms
    • Nakao M, Sasaki H (1996): Genomic imprinting: Significance in development and diseases and the molecular mechanisms. J Biochem 120:467-473.
    • (1996) J Biochem , vol.120 , pp. 467-473
    • Nakao, M.1    Sasaki, H.2
  • 43
    • 0028209550 scopus 로고
    • New insights reveal complex mechanisms involved in genomic imprinting
    • Nicholls RD (1994): New insights reveal complex mechanisms involved in genomic imprinting [editorial; comment]. Am J Hum Genet 54:733-740.
    • (1994) Am J Hum Genet , vol.54 , pp. 733-740
    • Nicholls, R.D.1
  • 44
    • 0026773169 scopus 로고
    • Molecular analysis of patients with Wiedemann-Beckwith syndrome. II. Paternally derived disomies of chromosome 11
    • Nystrom A, Cheetham JE, Engstrom W, Schofield PN (1992): Molecular analysis of patients with Wiedemann-Beckwith syndrome. II. Paternally derived disomies of chromosome 11. Eur J Pediatr 151:511-514.
    • (1992) Eur J Pediatr , vol.151 , pp. 511-514
    • Nystrom, A.1    Cheetham, J.E.2    Engstrom, W.3    Schofield, P.N.4
  • 45
    • 0027422302 scopus 로고
    • Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumor and gigantism
    • Ogawa O, Becroft DM, Morison IM, Eccles MR, Skeen JE, Mauger DC, Reeve AE (1993): Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumor and gigantism. Nat Genet 5:408-412.
    • (1993) Nat Genet , vol.5 , pp. 408-412
    • Ogawa, O.1    Becroft, D.M.2    Morison, I.M.3    Eccles, M.R.4    Skeen, J.E.5    Mauger, D.C.6    Reeve, A.E.7
  • 46
    • 0028089079 scopus 로고
    • Overlapping patterns of IGF2 and H19 expression during human development: Biallelic IGF2 expression correlates with a lack of H19 expression
    • Ohlsson R, Hedborg F, Holmgren L, Walsh C, Ekstrom TJ (1994): Overlapping patterns of IGF2 and H19 expression during human development: Biallelic IGF2 expression correlates with a lack of H19 expression. Development 120:361-368.
    • (1994) Development , vol.120 , pp. 361-368
    • Ohlsson, R.1    Hedborg, F.2    Holmgren, L.3    Walsh, C.4    Ekstrom, T.J.5
  • 47
    • 0023011534 scopus 로고
    • An infant with Beckwith-Wiedemann syndrome and chromosomal duplication 11p13-pter: Correlation of symptoms between 11p trisomy and Beckwith-Wiedemann syndrome
    • Okano YOY, Yamamoto H, Hase Y, Tsuruhara T, Fujita H (1986): An infant with Beckwith-Wiedemann syndrome and chromosomal duplication 11p13-pter: Correlation of symptoms between 11p trisomy and Beckwith-Wiedemann syndrome. Jpn J Hum Genet 31:365-372.
    • (1986) Jpn J Hum Genet , vol.31 , pp. 365-372
    • Okano, Y.O.Y.1    Yamamoto, H.2    Hase, Y.3    Tsuruhara, T.4    Fujita, H.5
  • 49
    • 0023891637 scopus 로고
    • Wiedemann-Beckwith syndrome in apparently discordant monozygotic twins
    • Olney AH, Buehler BA, Waziri M (1988): Wiedemann-Beckwith syndrome in apparently discordant monozygotic twins. Am J Med Genet 29:491-499.
    • (1988) Am J Med Genet , vol.29 , pp. 491-499
    • Olney, A.H.1    Buehler, B.A.2    Waziri, M.3
  • 50
    • 0028964550 scopus 로고
    • Non-random X chromosome inactivation in an affected twin in a monozygotic twin pair discordant for Wiedemann-Beckwith syndrome
    • Orstavik RE, Tommerup N, Eiklid K, Orstavik KH (1995): Non-random X chromosome inactivation in an affected twin in a monozygotic twin pair discordant for Wiedemann-Beckwith syndrome. Am J Med Genet 56: 210-214.
    • (1995) Am J Med Genet , vol.56 , pp. 210-214
    • Orstavik, R.E.1    Tommerup, N.2    Eiklid, K.3    Orstavik, K.H.4
  • 51
    • 0022910322 scopus 로고
    • Wiedemann-Beckwith syndrome: Presentation of clinical and cytogenetic data on 22 new cases and review of the literature
    • Pettenati MJ, Haines JL, Higgins RR, Wappner RS, Palmer CG, Weaver DD (1986): Wiedemann-Beckwith syndrome: Presentation of clinical and cytogenetic data on 22 new cases and review of the literature. Hum Genet 74:143-154.
    • (1986) Hum Genet , vol.74 , pp. 143-154
    • Pettenati, M.J.1    Haines, J.L.2    Higgins, R.R.3    Wappner, R.S.4    Palmer, C.G.5    Weaver, D.D.6
  • 54
  • 55
    • 0030856668 scopus 로고    scopus 로고
    • Imprinting in clusters: Lessons from Beckwith-Wiedemann syndrome
    • Reik W, Maher ER (1997): Imprinting in clusters: Lessons from Beckwith-Wiedemann syndrome. Trends Genet 13:330-334.
    • (1997) Trends Genet , vol.13 , pp. 330-334
    • Reik, W.1    Maher, E.R.2
  • 56
    • 0001811034 scopus 로고    scopus 로고
    • General principles of the epidemiology of childhood cancer
    • Pizzo PA, Poplack D (eds): Philadelphia: Lippincott-Raven Publishers
    • Robison L (1997): General principles of the epidemiology of childhood cancer. In Pizzo PA, Poplack D (eds): "Principles and Practice of Pediatric Oncology." Philadelphia: Lippincott-Raven Publishers, pp 1-10.
    • (1997) Principles and Practice of Pediatric Oncology , pp. 1-10
    • Robison, L.1
  • 57
    • 0030823992 scopus 로고    scopus 로고
    • Paternally inherited duplications of Ilpl5.5 and Beckwith-Wiedemann syndrome
    • Slavotinek A, Gaunt L, Donnai D (1997): Paternally inherited duplications of Ilpl5.5 and Beckwith-Wiedemann syndrome. J Med Genet 34:819-826.
    • (1997) J Med Genet , vol.34 , pp. 819-826
    • Slavotinek, A.1    Gaunt, L.2    Donnai, D.3
  • 58
    • 0030960876 scopus 로고    scopus 로고
    • OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2
    • Song HH, Shi W, Filmus J (1996): OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2. J Biol Chem 272:7574-7577.
    • (1996) J Biol Chem , vol.272 , pp. 7574-7577
    • Song, H.H.1    Shi, W.2    Filmus, J.3
  • 59
    • 0029985838 scopus 로고
    • Genomic imprinting in tumors
    • Squire J, Shear D (eds): "Gene Rearrangements and Cancer," New York: Academic Press
    • Squire J, Weksberg R (1995): Genomic imprinting in tumors. In Squire J, Shear D (eds): "Gene Rearrangements and Cancer," Vol. 7. Seminars in Cancer Biology. New York: Academic Press, pp 41-47.
    • (1995) Seminars in Cancer Biology , vol.7 , pp. 41-47
    • Squire, J.1    Weksberg, R.2
  • 60
    • 0030735169 scopus 로고    scopus 로고
    • Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome
    • Sun FI, Dean WL, Kelsey G, Allen NA, Reik W (1997): Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389:809-815.
    • (1997) Nature , vol.389 , pp. 809-815
    • Sun, F.I.1    Dean, W.L.2    Kelsey, G.3    Allen, N.A.4    Reik, W.5
  • 62
    • 0028935017 scopus 로고
    • Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor
    • Taniguchi T, Sullivan MJ, Ogawa O, Reeve AE (1995b): Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor. Proc Natl Acad Sci USA 92:2159-2163.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2159-2163
    • Taniguchi, T.1    Sullivan, M.J.2    Ogawa, O.3    Reeve, A.E.4
  • 63
    • 0014764924 scopus 로고
    • Exomphalosmacroglossia-gigantism syndrome in Jamaican infants
    • Thornburn M, Wright E, Miller C, Smith-Read E (1970): Exomphalosmacroglossia-gigantism syndrome in Jamaican infants. Am J Dis Child 119:316-321.
    • (1970) Am J Dis Child , vol.119 , pp. 316-321
    • Thornburn, M.1    Wright, E.2    Miller, C.3    Smith-Read, E.4
  • 64
    • 0030989158 scopus 로고    scopus 로고
    • Altered transcriptional regulation of the insulin-like growth factor 2 gene in human hepatocellular carcinoma
    • Uchida K, Kondo M, Takeda S, Osada H, Takahashi T, Nakao A, Takahashi T (1997): Altered transcriptional regulation of the insulin-like growth factor 2 gene in human hepatocellular carcinoma. Mol Carcinog 18:193-198.
    • (1997) Mol Carcinog , vol.18 , pp. 193-198
    • Uchida, K.1    Kondo, M.2    Takeda, S.3    Osada, H.4    Takahashi, T.5    Nakao, A.6    Takahashi, T.7
  • 65
    • 0029931018 scopus 로고    scopus 로고
    • Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor
    • Vu TH, Hoffman A (1996): Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor. J Biol Chem 271:9014-9023.
    • (1996) J Biol Chem , vol.271 , pp. 9014-9023
    • Vu, T.H.1    Hoffman, A.2
  • 67
    • 0025633055 scopus 로고
    • Molecular characterization of Beckwith-Wiedemann syndrome (WBS) patients with partial duplication of chromosome lip excludes the gene MYOD1 from the WBS region
    • Weksberg R, Glaves M, Teshima I, Waziri M, Patil S, Williams BR (1990): Molecular characterization of Beckwith-Wiedemann syndrome (WBS) patients with partial duplication of chromosome lip excludes the gene MYOD1 from the WBS region. Genomics 8:693-698.
    • (1990) Genomics , vol.8 , pp. 693-698
    • Weksberg, R.1    Glaves, M.2    Teshima, I.3    Waziri, M.4    Patil, S.5    Williams, B.R.6
  • 68
    • 0027420362 scopus 로고
    • Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome
    • Weksberg R, Shen DR, Fei YL, Song QL, Squire J (1993a): Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome. Nat Genet 5:143-150.
    • (1993) Nat Genet , vol.5 , pp. 143-150
    • Weksberg, R.1    Shen, D.R.2    Fei, Y.L.3    Song, Q.L.4    Squire, J.5
  • 69
    • 0027289089 scopus 로고
    • Molecular characterization of cytogenetic alterations associated with the Beckwith-Wiedemann syndrome (WBS) phenotype refines the localization and suggests the gene for WBS is imprinted
    • Weksberg R, Teshima I, Williams BR, Greenberg CR, Pueschel SM, Chernos JE, Fowlow SB, Hoyme E, Anderson IJ, Whiteman DA (1993b): Molecular characterization of cytogenetic alterations associated with the Beckwith-Wiedemann syndrome (WBS) phenotype refines the localization and suggests the gene for WBS is imprinted. Hum Mol Genet 2:549-556.
    • (1993) Hum Mol Genet , vol.2 , pp. 549-556
    • Weksberg, R.1    Teshima, I.2    Williams, B.R.3    Greenberg, C.R.4    Pueschel, S.M.5    Chernos, J.E.6    Fowlow, S.B.7    Hoyme, E.8    Anderson, I.J.9    Whiteman, D.A.10
  • 70
    • 0029848437 scopus 로고    scopus 로고
    • Molecular biology of Beckwith-Wiedemann syndrome
    • Weksberg R, Squire JA (1996): Molecular biology of Beckwith-Wiedemann syndrome. Med Pediatr Oncol 27:462-469.
    • (1996) Med Pediatr Oncol , vol.27 , pp. 462-469
    • Weksberg, R.1    Squire, J.A.2
  • 71
    • 76549164702 scopus 로고
    • Complexe malformatif familial avec hernie ombilicale et macroglossie: Un syndrome nouveau?
    • Wiedemann HR (1964): Complexe malformatif familial avec hernie ombilicale et macroglossie: Un syndrome nouveau? J Génét Hum 13:223-232.
    • (1964) J Génét Hum , vol.13 , pp. 223-232
    • Wiedemann, H.R.1
  • 72
    • 34250134720 scopus 로고
    • Tumors and hemihypertrophy associated with the Wiedemann-Beckwith syndrome
    • Wiedemann HR (1983): Tumors and hemihypertrophy associated with the Wiedemann-Beckwith syndrome. Eur J Pediatr 141:129.
    • (1983) Eur J Pediatr , vol.141 , pp. 129
    • Wiedemann, H.R.1
  • 73
    • 0030955563 scopus 로고    scopus 로고
    • KIP2 results in increased apoptosis and delayed dif-ferentiation during mouse development
    • KIP2 results in increased apoptosis and delayed dif-ferentiation during mouse development. Genes Dev 11:973-983.
    • (1997) Genes Dev , vol.11 , pp. 973-983
    • Yan, Y.1    Frisen, J.2    Lee, M.H.3    Massague, J.4    Barbacid, M.5
  • 74
    • 0028229910 scopus 로고
    • Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma
    • Zhan S, Shapiro DN, Helman LJ (1994): Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J Clin Invest 94:445-448.
    • (1994) J Clin Invest , vol.94 , pp. 445-448
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3
  • 75
    • 0029588595 scopus 로고
    • Loss of imprinting of IGF2 in Ewing's sarcoma
    • Zhan S, Shapiro DN, Helman LJ (1995): Loss of imprinting of IGF2 in Ewing's sarcoma. Oncogene 11:2503-2507.
    • (1995) Oncogene , vol.11 , pp. 2503-2507
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.