Cellular folates prevent polyglutamation of 5,10- dideazatetrahydrofolate: A novel mechanism of resistance to folate antimetabolites

Journal of Biological Chemistry

Volumn 273, Issue 40, 1998, Pages 25944-25952

  Tse, Archie ^a   Moran, Richard G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID ANTAGONIST; LOMETREXOL; RALTITREXED;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL MEMBRANE RESISTANCE; CELL MEMBRANE TRANSPORT; CELL PROLIFERATION; CELL SURVIVAL; CYTOTOXICITY; ENZYME SYNTHESIS; FOLATE METABOLISM; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; XENOGRAFT;

ANIMALS; BIOLOGICAL TRANSPORT; CELL DIVISION; DRUG RESISTANCE; FEEDBACK; FOLIC ACID; HYDROXYMETHYL AND FORMYL TRANSFERASES; KINETICS; LEUKEMIA L1210; MICE; PEPTIDE SYNTHASES; PHENOTYPE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PTEROYLPOLYGLUTAMIC ACIDS; RNA, MESSENGER; TETRAHYDROFOLATES; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032475855     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.40.25944     Document Type: Article

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