Tight binding of folate substrates and inhibitors to recombinant mouse glycinamide ribonucleotide formyltransferase

Biochemistry

Volumn 36, Issue 34, 1997, Pages 10506-10516

  Sanghani, Sonal P ^a   Moran, Richard G ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,8 DIDEAZAFOLIC ACID DERIVATIVE; ENZYME INHIBITOR; FOLIC ACID ANTAGONIST; LOMETREXOL; N [5 [2 (2 AMINO 1,4,5,6,7,8 HEXAHYDRO 4 OXOPYRIDO[2,3 D]PYRIMIDIN 6 YL)ETHYL] 2 THENOYL]GLUTAMIC ACID; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITOR INTERACTION; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; EQUILIBRIUM DIALYSIS; FEMALE; INHIBITION KINETICS; INSECT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PURINE SYNTHESIS; STEADY STATE;

ACYLTRANSFERASES; ANIMALS; BINDING, COMPETITIVE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FOLIC ACID; FOLIC ACID ANTAGONISTS; HYDROXYMETHYL AND FORMYL TRANSFERASES; KINETICS; MICE; MOLECULAR STRUCTURE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; POLYGLUTAMIC ACID; PROTEIN BINDING; RECOMBINANT PROTEINS; SPODOPTERA; TETRAHYDROFOLATES; TUMOR CELLS, CULTURED;

ANIMALIA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0030803790     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970825u     Document Type: Article

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