Keratinocyte-specific retinoid regulation of human Cellular Retinoic Acid Binding Protein-II (hCRABPII) gene promoter requires an evolutionary conserved DR1 retinoic acid-responsive element

Journal of Investigative Dermatology

Volumn 111, Issue 6, 1998, Pages 1109-1115

  Di, Wen ^a   Li, Xiao Yan ^a   Datta, Subhash ^b   Åström, Anders ^a   Fisher, Gary J ^c   Chambon, Pierre ^a   Voorhees, John J ^a   Xiao, Jia Hao ^a,d  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b ASTRAZENECA R AND D   (Sweden)

^c Centre de Recherche Interdisciplinaire en Biologie   (France)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Gene regulation; Heterodimers; Retinoid receptors; Skin

Indexed keywords

RETINOIC ACID BINDING PROTEIN; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; KERATINOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

BASE SEQUENCE; CELLS, CULTURED; CONSERVED SEQUENCE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIMERIZATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; KERATINOCYTES; PROMOTER REGIONS (GENETICS); RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; TRANSCRIPTION FACTORS; TRETINOIN;

EID: 0032464309     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00455.x     Document Type: Article

References (48)

1. Algermissen D, Sitzmann J, LeMotte P, Czarnietzki B: Differential expression of CRABPII, psoriasin and cytokeratin I mRNA in human skin diseases. Arch Dermatol Res 288:426-430, 1996
2. Astrom A, Tavakkol A, Pettersson U, Cromie M, Elder JT, Voorhees JJ: Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP). Retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro. J Biol Chem 266:17662-17666, 1991
3. Astrom A, Pettersson U, Chambon P, Voorhees JJ: Retinoic acid induction of human cellular retinoic acid-binding protein-II gene transcription is mediated by retinoic acid receptor- retinoid X receptor heterodimers bound to one far upstream retinoic acid-responsive element with 5-base pair spacing. J Biol Chem 269:22334-22339, 1994
4. Barger PM, Kelley DP: Identification of a retinoid/chicken ovalbumin upstream promoter transcription factor response element in the human retinoid X receptor γ2 gene promoter. J Biol Chem 272:2722-2728, 1997
5. Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y: A dynamic balance between ARP-1/ COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 15:1034-1048, 1995
6. Bucco RA, Zheng WL, Davis JT, Sierra-Rivera E, Osteen KG, Chaudhary AK, Ong DE: Cellular retinoic acid-binding protein (II) presence in rat uterine epithelial cells correlates with their synthesis of retinoic acid. Biochem 36:4009-4014, 1997
7. Chambon P: A decade of molecular biology of retinoic acid receptors. FASEB J 10:940-954, 1996
8. Chen JY, Clifford J, Zusi C, et al: Two distinct actions of retinoid-receptor ligands. Nature 382:819-822, 1996
9. Chiba H, Clifford J, Metzger D, Chambon P: Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Mol Cell Biol 17:3013-3020, 1997
10. Dignam JD, Lebovitz RM, Roeder RG: Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Aids Res 11:1475-1489, 1983
11. DiRenzo J, Soderstrom M, Kurokawa R, et al: Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol Cell Biol 17:2166-2176, 1997
12. Durand B, Saunders M, Leroy P, Leid M, Chambon P: All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. Cell 71:73-85, 1992
13. Elder JT, Astrom A, Pettersson U, et al: Retinoic acid receptors and binding proteins in human skin. J Invest Dermatol 98:365-41S, 1992
14. Feng X, Di Peng ZHW, Li XY, Rochette-Egly C, Chambon P, Voorhees JJ, Xiao JH: Suprabasal expression of a dominant-negative RXRα mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes Dev 11:59-71, 1997
15. Fisher GJ, Voorhees JJ: Molecular mechanisms of retinoid actions in skin. FASEB J 10:1002-1013, 1996
16. Fisher GJ, Talwar HS, Xiao JH, et al: Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin. J Biol Chem 269:20629-20635, 1994
17. Forman BM, Umesono K, Chen J, Evans RM: Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81:541-550, 1995
18. Gendimenico GJ, Mallon JP, Cromie MA, Astrom A, Elder JT: Regulation of cellular retinoic acid protein expression in rhino mouse skin by all-trans-retinoic acid. Skin Pharmacol 8:167-172, 1995
19. Glass CK, Rose DW, Rosenfeld MG: Nuclear receptor coactivators. Curr Opin Cell Biol 9:222-232, 1997
20. Gronemeyer H, Moras D: How to finger DNA. Nature 375:190-191, 1995
21. Jing Y, Waxman S, Mira-y-Lopez R: The cellular retinoic acid binding protein II is a positive regulator of retinoic acid signaling in breast cancer cells. Cancer Res 57:1668-1672, 1997
22. Kastner P, Mark M, Chambon P: Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life. Cell 83:859-869, 1995
23. Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM: Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signaling. Nature 355:446-449, 1992
24. Kurokawa R, DiRenzo J, Boehm M, et al: Regulation of retinoid signaling by receptor polarity and allosteric control of ligand binding. Nature 371:528-531, 1994
25. Kurokawa R, Soderstorm M, Horlein A, Halachml S, Brown M, Rosenfeld MG, Glass CK: Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377:451-454, 1995
26. Lala DS, Mukherjee R, Schulman IG, et al: Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 383:450-453, 1996
27. Lee MO, Liu Y, Zhang XK: A retinoic acid response element that overlaps an estrogen response element mediates multihormonal sensitivity in transcriptional activation of the lactoferrin gene. Mol Cell Biol 15:4194-4207, 1995
28. Li E, Norris AW: Structure/function of cytoplasmic vitamin A-binding proteins. Annu Rev Nutr 16:205-234, 1996
29. Liu Y, Chiu JF: Transactivation and repression of the α-fetoprotein gene promoter by retinoid X receptor and chicken ovalbumin upstream promoter transcription factor. Nucleic Acid Res 22:1079-1086, 1994
30. Mader S, Chen JY, Chen Z, White J, Chambon P, Gronemeyer H: The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificities of the DNA binding domains. EMBO J 12:5029-5041, 1993
31. Mangelsdorf DJ, Evans RM: The RXR heterodimers and orphan receptors. Cell 83:841-850, 1995
32. Mangelsdorf DJ, Umesono K, Kliewer SA, Borgmeyer U, Ong ES, Evans RM: A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell 66:555-561, 1991
33. Martin B, Bernardon JM, Cavey MT, et al: Selective synthetic ligands for human nuclear retinoic acid receptors. Skin Pharmacol 5:57-65, 1992
34. Means AL, Gudas LJ: The roles of retinoids in vertebrate development. Annu Rev Biochem 64:201-233, 1995
35. Minucci S, Leid M, Toyama R, et al: Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression. Mol Cell Biol 17:644-655, 1997
36. Nakshatri H, Chambon P: The directly repeated RG (G/T) TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers. J Biol Chem 269:890-902, 1994
37. Napoli J: Biochemical pathways of retinoid transport, metabolism, and signal transduction. Clin Immunol Immunopathol 80:S52-S62, 1996
38. Perlmann T, Rangarajan PN, Umesono K, Evans RM: Determinants for selective RAR and TR recognition of direct repeat HREs. Genes Dev 7:1411-1422, 1993
39. Roy B, Taneja R, Chambon P: Synergistic activation of retinoic acid (RA) -responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor α (RARα) -, RARβ-, or RARγ-selective ligand in combination with a retinoid X receptor-specific ligand. Mol Cell Biol 15:6481-6487, 1995
40. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press, 1989
41. Schulman IG, Li C, Schwabe JWR, Evans RM: The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. Genes Dev 11:299-308, 1997
42. Soderstrom M, Vo A, Heinzel T, et al: Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes. Mol Endocrinol 11:682-692, 1997
43. Torma H, Lontz W, Liu W, Rollman O, Vahlquist A: Expression of cytosolic retinoid-binding protein genes in human skin biopsies and cultured keratinocytes and fibroblasts. Br J Dermnatol 131:243-249, 1994
44. Vahlquist A, Andersson E, Coble BI, Rollman O, Torma H: Increased concentrations of 3,4-didehydroretinol and retinoic acid-binding protein (CRABPII) in human squamous cell carcinoma and keratoacanthoma but not in basal cell carcinoma of the skin. J Invest Dermatol 106:1070-1074, 1996
45. Vu-Dac N, Schoonjans K, Kosykh V, Dallongeville J, Heyman RA, Staels B, Auwerx J: Retinoids increase human apolipoprotein A-II expression through activation of the retinoid X receptor but not the retinoic acid receptor. Mol Cell Biol 16:3350-3360, 1996
46. Xiao JH, Davidson I, Matthes H, Garnier JM, Chambon P: Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1. Cell 65:551-568, 1991
47. Xiao JH, Durand B, Chambon P, Voorhees JJ: Endogenous retinoic acid receptor (RAR) - retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid- responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand- dependent activation of hRARβ2/RARE (DR5). J Biol Chem 270:3001-3011, 1995
48. Zou CP, Clifford JL, Xu XC, Sacks PG, Chambon P, Hong WK, Lotan R: Modulation by retinoic acid (RA) of squamous cell differentiation, cellular RA-binding proteins, and nuclear RA receptors in human head and neck squamous cell carcinoma cell lines. Cancer Res 54:5479-5487, 1994