Molecular characterization of the gene encoding the DNA gyrase A subunit of Streptococcus pneumoniae

Journal of Bacteriology

Volumn 180, Issue 11, 1998, Pages 2854-2861

  Balas, Delia ^a   Fernández Moreira, Esteban ^a   De La Campa, Adela G ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; DNA TOPOISOMERASE (ATP HYDROLYSING);

ARTICLE; CONTROLLED STUDY; DNA CONFORMATION; DNA SEQUENCE; ENZYME SUBUNIT; GENE EXPRESSION SYSTEM; GENE SEQUENCE; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RESTRICTION MAPPING; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

ESCHERICHIA COLI; STREPTOCOCCUS PNEUMONIAE;

EID: 0032463438     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.11.2854-2861.1998     Document Type: Article

References (48)

1. Adams, D. E., E. M. Shekhtman, E. L. Zechiedrich, M. B. Schmid, and N. R. Cozzarelli. 1992. The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication. Cell 71:277-288.
2. Baquero, F. 1996. Epidemiology and management of penicillin-resistant pneumococci. Curr. Opin. Infect. Dis. 9:372-379.
3. 70 subunit is responsible for the recognition of the 'extended-10' motif at promoters. EMBO J. 13:4034-4040.
4. Belland, R., S. Morrison, C. Ison, and W. Huang. 1994. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol. Microbiol. 14:371-380.
5. Blanche, F., B. Cameron, F. X. Bernard, L. Maton, B. Manse, L. Ferrero, N. Ratet, C. Lecoq, A. Goniot, D. Bisch, and J. Crouzet. 1996. Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases. Antimicrob. Agents Chemother. 40:2714-2720.
6. Carty, M., and R. Menzel. 1990. Inhibition of DNA gyrase activity in an in vitro transcription-translation system stimulates gyrA expression in a DNA concentration manner. J. Mol. Biol. 214:397-406.
7. Dente, L., G. Cesareni, and R. Cortese. 1983. pEMBL: a new family of single stranded plasmids. Nucleic Acids Res. 11:1645-1655.
8. +-ATPases. Mol. Microbiol. 12:587-598.
9. Ferrero, L., B. Cameron, B. Manse, D. Langeaux, J. Crouzet, A. Famechon, and F. Blanche. 1994. Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones. Mol. Microbiol. 13:641-653.
10. Gellert, M. 1981. DNA topoisomerases. Annu. Rev. Biochem. 50:879-910.
11. Georgiou, M., R. Muñoz, F. Román, R. Cantón, R. Gómez-Lus, J. Campos, and A. G. de la Campa. 1996. Ciprofloxacin-resistant Haemophilus influenzae strains possess mutations in analogous positions of GyrA and ParC. Antimicrob. Agents Chemother. 40:1741-1744.
12. Graves, M. C., and J. C. Rabonowitz. 1986. In vivo and in vitro transcription of the Clostridium pasteurianum ferredoxin gene. Evidence for extended promoter elements in gram-positive organisms. J. Biol. Chem. 25:11409-11415.
13. Hanahan, D. 1985. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:557-580.
14. Huang, W. M. 1996. Bacterial diversity based on type II DNA topoisomerase genes. Annu. Rev. Genet. 30:79-107.
15. Janoir, C., V. Zeller, M.-D. Kitzis, N. J. Moreau, and L. Gutmann. 1996. High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA. Antimicrob. Agents Chemother. 40:2760-2764.
16. Kato, J., Y. Nishimura, K. Imamura, H. Niki, S. Higara, and H. Suzuki. 1990. New topoisomerase essential for chromosome segregation in E. coli. Cell 63:393-404.
17. Keilty, S., and M. Rosenberg. 1987. Constitutive function of a positively regulated promoter reveals new sequences essential for activity. J. Biol. Chem. 262:6389-6395.
18. Khodursky, A. B., E. L. Zechiedrich, and N. R. Cozarelli. 1995. Topoisomerase IV is a target of quinolones in Escherichia coli. Proc. Natl. Acad. Sci. USA 92:11801-11805.
19. Korten, V., W. M. Huang, and B. E. Murray. 1994. Analysis by PCR and direct sequencing of gyrA mutations associated with fluoroquinolone resistance in Enterococcus faecalis. Antimicrob. Agents Chemother. 38:2091-2094.
20. Kumar, A., R. A. Malloch, N. Fujita, D. A. Smillie, A. Ishihama, and R. S. Hayward. 1993. The minus 35-recognition region of Escherichia coli sigma 70 is inessential for initiation of transcription at an "extended minus 10" promoter. J. Mol. Biol. 232:406-418.
21. Magerrison, E. E. C., R. Hopewell, and L. M. Fisher. 1992. Nucleotide sequence of the Staphylococcus aureus gyrB-gyrA locus encoding the DNA gyrase A and B proteins. J. Bacteriol. 174:1596-1603.
22. Maxwell, A. 1997. DNA gyrase as a drug target. Trends Microbiol. 5:102-109.
23. Menzel, R., and M. Gellert. 1987. Modulation of transcription by DNA supercoiling: a deletion analysis of the Escherichia coli gyrA and gyrB promoters. Proc. Natl. Acad. Sci. USA 84:4185-4189.
24. Menzel, R., and M. Gellert. 1983. Regulation of the genes for E. coli DNA gyrase: homeostatic control of DNA supercoiling. Cell 34:105-113.
25. Mizuuchi, K., H. O'Dea, and M. Gellert. 1978. DNA gyrase: subunit structure and ATPase activity of the purified enzyme. Proc. Natl. Acad. Sci. USA 75:5960-5963.
26. Morals Cabrai, J. H., A. P. Jackson, C. V. Smith, N. Shikotra, A. Maxwell, and R. C. Liddington. 1997. Crystal structure of the breakage-reunion domain of DNA gyrase. Nature 388:903-906.
27. Moriya, S., N. Ogasawara, and H. Yoshikawa. 1985. Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. III. Nucleotide sequence of some 10,000 base pairs in the origin region. Nucleic Acids Res. 13:2251-2265.
28. Muñoz, R., M. Bustamante, and A. G. de la Campa. 1995. Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance. J. Bacteriol. 177:4166-4170.
29. Muñoz, R., and A. G. de la Campa. 1996. ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype. Antimicrob. Agents Chemother. 40:2252-2257.
30. Pan, X. S., and L. M. Fisher. 1997. Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones. Antimicrob. Agents Chemother. 41:471-474.
31. Pan, X.-S., J. Ambler, S. Mehtar, and L. M. Fisher. 1996. Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 40:2321-2326.
32. Pan, X.-S., and L. M. Fisher. 1996. Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance. J. Bacteriol. 178:4060-4069.
33. Pérez-Martín, J., F. Rojo, and V. de Lorenzo. 1994. Promoters responsive to DNA bending: a common theme in prokaryotic gene expression. Microbiol. Rev. 58:268-290.
34. Ponnambalan, S., C. Webster, A. Bingham, and S. Busby. 1986. Transcription initiation at the E. coli galactose operon promoters in the absence of the normal -35 region sequences. J. Biol. Chem. 261:16043-16048.
35. Prentki, P., M.-H. Pham, and D. J. Galas. 1987. Plasmid permutation vectors to monitor DNA bending. Nucleic Acids Res. 15:10060.
36. Sabelnikov, A. G., B. Greenberg, and S. A. Lacks. 1995. An extended -10 promoter alone directs transcription of the DpnII operon of Streptococcus pneumoniae. J. Mol. Biol. 250:144-155.
37. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
38. Shine, J., and L. Dalgarno. 1975. Determinants of cistron specificity in bacterial ribosomes. Nature 254:34-38.
39. Studier, F. W., A. H. Rosenberg, J. J. Dunn, and J. W. Dubendorff. 1990. Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol. 185:60-89.
40. Sugino, A., N. P. Higgins, P. O. Brown, C. L. Peebles, and N. R. Cozzarelli. 1978. Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Proc. Natl. Acad. Sci. USA 75:4838-4842.
41. Sugino, A., C. L. Peebles, K. N. Kreuzer, and N. R. Cozzarelli. 1977. Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase, a novel nicking-closing enzyme. Proc. Natl. Acad. Sci. USA 74:4767-1771.
42. Swanberg, S. L., and J. C. Wang. 1987. Cloning and sequencing of the Escherichia coli DNA gyrA gene coding for the A subunit of DNA gyrase. J. Mol. Biol. 197:729-736.
43. Tankovic, J., B. Perichon, J. Duval, and P. Courvalin. 1996. Contribution of mutations in gyrA and parC genes to fluoroquinolone resistance of mutants of Streptococcus pneumoniae obtained in vivo and in vitro. Antimicrob. Agents Chemother. 40:2505-250.
44. Wang, J. C. 1985. DNA topoisomerases. Annu. Rev. Biochem. 54:665-697.
45. Wolfson, J. S., and D. C. Hooper. 1989. Fluoroquinolone antimicrobial agents. Clin. Microbiol. Rev. 2:378-424.
46. Wu, H.-M., and D. M. Crothers. 1984. The locus of sequence-directed and protein-induced DNA bending. Nature 308:509-513.
47. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC9 vectors. Gene 33:103-119.
48. Yoshida, H., M. Bogaki, M. Nakamura, and S. Nakamura. 1990. Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. Antimicrob. Agents Chemother. 34:1271-1272.