Compensating lipid fluxes generated by the aminophospholipid translocase

Molecular Membrane Biology

Volumn 15, Issue 4, 1998, Pages 213-220

  Frickenhaus, Stephan ^a   Herrmann, Andreas ^a   Heinrich, Reinhart ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Aminophospholipid translocase; Compensating flux; Floppase; Mechanical stress; Thermodynamic model

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINOPHOSPHOLIPID; CARRIER PROTEIN; LIPID;

ARTICLE; DRUG CONCENTRATION; ENZYME ACTIVITY; ERYTHROCYTE; KINETICS; LIPID BILAYER; LIPID TRANSPORT; MECHANICAL STRESS; MODEL; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 0032451296     PISSN: 09687688     EISSN: None     Source Type: Journal    
DOI: 10.3109/09687689709044323     Document Type: Article

References (50)

1. Auland, M. E., Roufogalis, B. D., Devaux, P. F. and Zachowski, A., 1994, Reconstitution of ATP-dependent aminophospholipid translocation in proteoliposomes. Proceeding of the National Academy of Science USA, 91, 10938-10942.
2. Bitbol, M. and Devaux, P. F., 1988, Measurement of outward translocation of phospholipids across human erythrocyte membrane. Proceedings of the National Academy of Science USA, 85, 6783-6787.
3. Boegheim Jr., J. P. J., Van Linde, M., Op Den Kamp, J. A. F. and Roelofsen, B., 1983, The sphingomyelin pools in the outer and inner layer of the human erythrocyte membrane are composed of different molecular species. Biochimica et Biophysica Acta, 735, 438-442.
4. Bosch, I., Dunussi-Joannopoulos, K., Wu, R. L., Furlong, S. T. and Croop, J., 1997, Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein. Biochemistry, 36, 5685-5694.
5. Brumen, M., Heinrich, R., Herrmann, A. and Müller, P., 1993, Mathematical modeling of lipid transbilayer movement in the human erythrocyte plasma membrane. European Biophysical Journal, 22, 213-223.
6. Calvez, J.-Y., Zachowski, A., Herrmann, A., Morrot, G. and Devaux, P. F., 1988, Asymmetric distribution of phospholipids in spectrin-poor erythrocyte vesicles. Biochemistry, 27, 5666-5670.
7. Colleau, M., Hervé, P., Fellmann, P. and Devaux, P. F., 1991, Transmembrane diffusion of fluorescent phospholipids in human erythrocytes. Chemistry and Physics of Lipids, 57, 29-37.
8. Connor, J., Gillum, K. and Schroit, A. J., 1990, Maintainance of lipid asymmetry in red blood cells and ghosts: effect of divalent cations and serum albumin on the transbilayer distribution of phosphatidylserine. Biochimica et Biophysica Acta, 1025, 82-86.
9. Connor, J., Pak, C. H., Zwaal, R. F. A. and Schroit, A. J., 1992, Bidirectional transbilayer movement of phospholipid analogs in human red blood cells - evidence for an atp-dependent and protein-mediated process. Journal of Biological Chemistry, 267, 19412-19417.
10. Daleke, D. L. and Huestis, W. H., 1985, Incorporation and translocation of aminophospholipids in human erythrocytes. Biochemistry, 24, 5406-5416.
11. Devaux, P. F., 1988, Phospholipid flippases. FEBS Letters, 234, 8-12.
12. Devaux, P. F. and Zachowski, A., 1994, Maintenance and consequences of membrane phospholipid asymmetry. Chemistry and Physics of Lipids, 73, 107-120.
13. Frickenhaus, S. and Heinrich, R., 1999, Kinetic and thermodynamic aspects of lipid translocation in biological membranes. Biophysical Journal, in press.
14. Frickenhaus, S. and Heinrich, R., 1998b, A kinetic model of interteaflet transport of lipids mediated by pore-forming proteins. In BioThermoKinetics in the post genomic era, C. Larsson, I.-L. Påhlman and L. Gustafsson, eds, (Göteborg, Sweden: Chalmers Reproservice), pp. 350-354.
15. Gerritsen, W. J., Henricks, P. A. J., de Kruijff, B. and van Deenen, L. L. M., 1980, The transbilayer movement of phosphatidylcholine in vesicles reconstituted with intrinsic proteins from the human erythrocyte membrane. Biochimica et Biophysica Acta, 600, 607-619.
16. Gudi, S. R. P., Kumar, A., Bhakuni, V., Gokhale, S. M. and Gupta, C. M., 1990, Membrane skeleton-bilayer interaction is not the major determinant of membrane phospholipid asymmetry in human erythrocytes. Biochimica et Biophysica Acta, 1023, 63-72.
17. Heinrich, R., Brumen, M., Jaeger, A., Müller, P. and Herrmann, A., 1997, Modelling of phospholipid translocation in the erythrocyte membrane: A combined kinetic and thermodynamic approach. Journal of Theoretical Biology, 185, 295-312.
18. Kamp, D. and Haest, C. W. M., 1998, Evidence for a role of the multidrug resistance protein (MRP) in the outward translocation of NBD-phospholipids in the erythrocyte membrane. Biochimica et Biophysica Acta, 1372, 91-101.
19. Kumar, A., Gudi, S. R. P., Gokhale, S. M., Bhakuni, V. and Gupta, C. M., 1990, Heat-induced alteration in monkey erythrocyte membrane phospholipid organization and skeletal protein structure and interactions. Biochimica et Biophysica Acta, 1030, 269-278.
20. Kuypers, F. A., Lubin, B. H., Yee, M., Agre, P., Devaux, P. F. and Geldwerth, D., 1993, The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry. Blood, 81, 1051-1057.
21. Martin, O. C. and Pagano, R. E., 1987, Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at the plasma membrane of cultured cells. Journal of Biological Chemistry, 262, 5890-5898.
22. Middelkoop, E., van der Hoek, E. E., Bevers, E. M., Comfurius, P., Slotboom, A. J., Op den Kamp, J. A. F., Lubin, B. H., Zwaal, R. F. A. and Roelofsen, B., 1989, Involvement of ATP-dependent aminophospholipid translocation in maintaining phospholipid asymmetry in diamide-treated human erythrocyte. Biochimica et Biophysica Acta, 981, 151-160.
23. Morrot, G., Hervé, P., Zachowski, A., Fellmann, P. and Devaux, P. F., 1989, Aminophospholipid translocase of human erythrocytes: phospholipid substrate specificity and effect of cholesterol. Biochemistry, 28, 3456-3462.
24. 2+-ATPase A candidate aminophospholipid translocase. FEBS Letters, 266, 29-32.
25. Müller, K., Pomorski, T., Müller, P., Zachowski, A. and Herrmann, A., 1994, Protein-dependent translocation of aminophospholipids and asymmetric transbilayer distribution of phospholipids in the plasma membrane of ram sperm cells. Biochemistry, 33, 9968-9974.
26. Müller, P., Pomorski, T., Porwoli, S., Tauber, R. and Herrmann, A., 1996, Transverse movement of spin-labeled phospholipids in the plasma membrane of a hepatocytic cell line (HepG2): Implications for biliary lipid secretion. Hepatology, 24, 1497-1503.
27. Op den Kamp, J. A. F., 1979, Lipid asymmetry in membranes. Annual Reviews in Biochemistry, 48, 47-71.
28. Pomorski, T., Müller, P., Zimmermann, B., Burger, K., Devaux, P. F. and Herrmann, A., 1996, Transbilayer movement of fluorescent and spin-labeled phospholipids in the plasma membrane of human fibroblasts: A quantitative approach. Journal of Cell Science, 109, 687-698.
29. Roelofsen, B. and Op den Kamp, J. A. F., 1987, Techniques to determine the transbilayer distribution and mobility of phospholipids in biological membranes. Biomembrane and Receptor Mechanism, 7, 41-57.
30. Roelofsen, B. and Op den Kamp, J. A. F., 1994, Plasma membrane phospholipid asymmetry and its maintenance: The human erythrocyte as a model. In Current Topics in Membranes, D. Hoeckstra, ed., vol 40 (San Diego: Academic Press), pp. 7-46.
31. Ruetz, S. and Gros, P., 1994, Phosphatidylcholine translocase: A physiological role for the mdr2 gene. Cell, 77, 1071-1081.
32. Schroit, A. J., 1994, Protein-mediated phospholipid movement in red blood cells. In Current Topics in Membranes, D. Hoeckstra, ed., vol 40 (San Diego: Academic Press), pp. 47-74.
33. Schroit, A. J. and Madsen, J. W., 1987, Radioiodinated photoactivatable phosphatidylcholine and phosphatidyl-serine: transfer properties and differential photoreactive interaction with human erythrocyte membrane proteins. Biochemistry, 26, 1812-1819.
34. Schroit, A. J., Bloy, C., Connor, J. and Cartron, J. P., 1990, Involvement of Rh blood group polypeptides in the maintenance of aminophospholipid asymmetry. Biochemistry, 29, 10303-10306.
35. Schultz, S. G., 1980, Basic principles of Membrane Transport (Cambridge: Cambridge University press).
36. Seigneuret, M. and Devaux, P. F., 1984, ATP-dependent asymmetric distribution of spin-labeled phospholipids in the erythrocyte membrane: Relation to shape changes. Proceedings of the National Academy of Science USA, 81, 3751-3755.
37. Smit, J. J., Schinkel, A. H., Oude Elferink, R. P. J., Groen, A. K., Wagenaar, E., vanDeemter, L., Mol, C. A. A. M., Ottenhoff, R., van der Lugt, N. M. T., van Roon, M. A., van der Valk, M. A., Offerhaus, G. J. A., Berns, A. J. M. and Borst, P., 1993, Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell, 75, 451-462.
38. Smith, A. J., Timmermans-Hereijgers, J. L. P. M., Roelofsen, B., Wirtz, K. W. A., Van Blitterswijk, W. J., Smit, J. J. M., Schinkel, A. H. and Borst, P., 1994, The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice. FEBS Letters, 354, 263-266.
39. Sune, A., Bette-Bobillo, P., Bienvene, A., Fellmann, P. and Devaux, P. F., 1987, Selective outside- inside translocation of aminophospholipids in human platelets. Biochemistry, 26, 2972-2978.
40. Svetina, S. and !c!, B., 1992, The elastic deformability of closed multilayered membranes is the same as that of a bilayer membrane. European Biophysical Journal, 21, 251-255.
41. Tang, X., Halleck, M. S., Schlegel, R. A. and Williamson, P., 1996, A subfamily of P-type ATPases with aminophospholipid transporting activity. Science, 272, 1495-1497.
42. Tilley, L., Cribier, S., Roelofsen, B., Op den Kamp, J. A. F. and van Deenen, L. L. M., 1986, ATP-dependent translocation of amino phospholipids across the human erythrocyte membrane. FEBS Letters, 194, 21-27.
43. van Helvoort, A., Giudici, M. L., Thielemans, M. and vanMeer, G., 1997, Transport of sphingomyelin to the cell surface is inhibited by brefeldin a and in mitosis, where C-6-NBD-sphingomyelin is translocated across the plasma membrane by a multidrug transporter activity. Journal of Cell Science, 110, 75-83.
44. van Helvoort, A., Smith, A. J., Sprong, H., Fritzsche, I., Schinkel, A. H., Borst, P. and vanMeer, G., 1996, MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell, 87, 507-517.
45. van Zoelen, de Kruijff, B. and van Deenen, L. L. M., 1978, Protein-mediated transbilayer movement of phosphatidylcholine in glycophorin containing vesicles. Biochimica et Biophysica Acta, 508, 97-108.
46. Williamson, P. and Schlegel, R. A., 1994, Back and forth: the regulation and function of transbilayer phospholipid movement in eukaryotic cells. Molecular Membrane Biology, 11, 199-216.
47. Williamson, P., Antia, R. and Schlegel, R. A., 1987, Maintenance of membrane phospholipid asymmetry. Lipid-cytoskeletal interactions or lipid pump? FEBS Letters, 219, 316-320.
48. Zachowski, A., 1993, Phospholipids in animal eukaryotic membranes - transverse asymmetry and movement. Biochemical Journal, 294, 1-14.
49. Zachowski, A., Fellmann, P., Hervé, P. and Devaux, P. F., 1987a, Labeling of human erythrocyte membrane proteins by photoactivatable radioiodinated phosphatidylcholine and phosphatidylserine. FEBS Letters, 223, 315-320.
50. Zachowski, A., Herrmann, A., Paraf, A. and Devaux, P. F., 1987b, Phospholipid outside-inside translocation in lymphocyte plasma membranes is a protein-mediated phenomenom. Biochimica et Biophysica Acta, 897, 197-200.