Modelling of phospholipid translocation in the erythrocyte membrane: A combined kinetic and thermodynamic approach

Journal of Theoretical Biology

Volumn 185, Issue 3, 1997, Pages 295-312

  Heinrich, Reinhart ^a   Brumen, Milan ^b   Jaeger, Annekathrin ^a   Müller, Peter ^c   Herrmann, Andreas ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF MARIBOR   (Slovenia)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARRIER PROTEIN; CHOLESTEROL; MEMBRANE PHOSPHOLIPID; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE; SPHINGOMYELIN;

ARTICLE; ERYTHROCYTE MEMBRANE; KINETICS; LIPID TRANSPORT; MATHEMATICAL MODEL; MEMBRANE TRANSPORT; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 0031557701     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1996.0325     Document Type: Article

References (41)

1. BACKER, J. & DAVIDOWICZ, E. A. (1981) Transmembrane movement of cholesterol in small unilamelar vesicles detected by cholesterol oxidase. J. Biol. Chem. 256, 13272-13277.
2. BELEZNAY, Z., ZACHOWSKI, A., DEVAUX, P. F., NAVAZO, M. P. & OTT, P. (1993). ATP-dependent aminophospholipid translocation in erythrocyte vesicles - Stoichiometry of transport. Biochemistry 32, 3146-3152.
3. BERGMANN, W. L., DRESSLER, V. & DEUTICKE, B. (1984). Reorientation rates and asymmetry of distribution of lysophopsholipids between the inner and outer leaflet of the erythrocyte membrane. Biochim. Biophys. Acta 772, 328-336.
4. BLAU, L. & BITTMANN, R. (1978). Cholesterol distribution between the two halves of the lipid bilayer of human erythrocyte ghosts membranes. J. Biol. Chem. 253, 8366-8368.
5. BITBOL, M. & DEVAUX, P. F. (1988). Measurement of outward translocation of phospholipids across human erythrocyte membrane. Proc. Natl. Acad. Sci. U.S.A. 85, 6738-6787.
6. BRASAEMLE, D. L., ROBERTSON, A. D. & ATTIE, A. D. (1988). Transbilayer movement of cholesterol in the human erythrocyte membrane. J. Lipid Res. 29, 481-489.
7. BRUMEN, M. & HEINRICH, R. (1984). A metabolic osmotic model of human erythrocytes. BioSystems 17, 155-169.
8. BRUMEN, M., HEINRICH, R., HERRMANN, A. & MÜLLER, P. (1993). Mathematical modelling of lipid transbilayer movement in the human erythrocyte membrane. Eur. Biophys. J. 22, 213-223.
9. CALVEZ, J. Y., ZACHOWSKI, A., HERRMANN, A., MORROT, G. & DEVAUX, P. F. (1988). Asymmetric distribution of phospholipids in spectrin-poor erythrocyte vesicles. Biochemistry 27, 5666-5670.
10. CANHAM, P. B. & BURTON, A. C. (1968). Distribution of size and shape in populations of normal human red cells. Circ. Res. 22, 405-422.
11. COLLEAU, M., HERVÉ, P., FELLMANN, P. & DEVAUX, P. F. (1991). Transmembrane diffusion of fluorescent phospholipids in human erythrocytes. Chem. Phys. Lipids 57, 29-37.
12. CONNOR, J., PAK, C. H., ZWAAL, R. F. A. & SCHROIT, A. J. (1992). Bidirectional transbilayer movement of phospholipid analogs in human red blood cells. J. Biol. Chem. 27, 19412-19417.
13. DALEKE, D. L. & HUESTIS, W. H. (1985). Incorporation and translocation of aminophospholipids in human erythrocytes. Biochemistry 24, 5406-5416.
14. DEVAUX P. F. (1991). Static and dynamic lipid asymmetry in cell membranes. Biochemistry 30, 1163-1173.
15. DEVAUX, P. F. (1992). Protein involvement in transmembrane lipid asymmetry. Annu. Rev. Biophys. Biomol. Struct. 21, 417-439.
16. FELL, D. A. (1992). Metabolic control analysis: a survey of its theoretical and experimental development. Biochem. J. 286, 313-330.
17. HAEST, C. W. M., PLASA, G., KAMP, D. & DEUTICKE, B. (1978). Spectrin as stabilizer of the phospholipid asymmetry in the erythrocyte membrane. Biochim. Biophys. Acta 509, 21-32.
18. HEINRICH, R. (1995). Principles of metabolic control theory. J. Biol. Syst. 3, 115-125.
19. HEINRICH, R. & RAPOPORT, T. A. (1973). Linear theory of enzymatic chains; its application for the analysis of the crossover theorem and of the glycolysis of human erythrocytes. Acta Biol. Med. Germ. 31, 479-494.
20. HEINRICH, R. & RAPOPORT, T. A. (1974). A linear steady state treatment of enzymatic chains. General properties, control and effector strength. Eur. J. Biochem. 42, 89-95.
21. HERRMANN, A. & MÜLLER, P. (1986). A model for the asymmetric lipid distribution in the human erythrocyte membrane. Biosci. Rep. 6, 185-191.
22. KACSER, H. & BURNS, J. (1973). The control of flux. Symp. Soc. Exp. Biol. 27, 65-104.
23. LANGE, Y., COHEN, C. M. & POZNANSKY, M. J. (1977). Transmembrane movement of cholesterol in human erythrocytes. Proc. Natl. Acad. Sci. U.S.A. 74, 1538-1542.
24. LANGE, Y., DOLDE, J. & STECK, T. L. (1981). The rate of transmembrane movement of cholesterol in human erythrocytes. J. Biol. Chem. 256, 5321-5323.
25. LANGE, Y. & SLAYTON, J. M. (1982). Interaction of cholesterol and lysophosphatidylcholine in determining red cell shape. J. Lipid Res. 23, 1121-1127.
26. LULY, P. (1989). Membrane lipid changes in the abnormal red cell. In: The Red Cell Membrane. A Model for Solute Transport. (Raess, B. U. & Tunnicliff, G., eds) pp. 399-421. Clifton: Humana Press.
27. MORROT, G., HERVÉ, P., ZACHOWSKI, A., FELLMANN, P. & DEVAUX, P. F. (1989). Aminophospholipid translocase of human erythrocytes: phospholipid substrate specificity and effect of cholesterol. Biochemistry 28, 3456-3462.
28. 2+-ATPase. FEBS Lett. 266, 29-32.
29. POMORSKI, T., MÜLLER, P., ZIMMERMANN, B., BURGER, K., DEVAUX. P. F. & HERRMANN, A. (1996). Transmembrane movement of fluorescent and spin-labeled phospholipids in the plasma membrane of human fibroblasts. A quantitative approach. J. Cell Sci. 109, 687-698.
30. ROSSO, J., ZACHOWSKI, A. & DEVAUX, P. F. (1988). Influence of chlorpromazine on the transverse mobility of phospholipids in the human erythrocyte membrane: Relation to shape changes. Biochim. Biophys. Acta 942, 271-279.
31. SCHRIER, S. L., ZACHOWSKI, A., HERVÉ, P., KADER, J. C. & DEVAUX, P. F. (1992). Transmembrane redistribution of phospholipids of the human red cell membrane during hypotonic hemolysis. Biochim. Biophys. Acta 1105, 170-176.
32. SCHROEDER, F., NEMECZ, G., WOOD, W. G., JOINER, C., MORROT, G., AYRAUT-JARRIER, M. & DEVAUX, P. F. (1991). Transmembrane distribution of sterol in the human erythrocyte. Biochim. Biophys. Acta 1066, 183-192.
33. SEIGNEURET, M. & DEVAUX. P. F. (1984). ATP-dependent asymmetric distribution of spin-labeled phospholipids in the erythrocyte membrane: Relation to shape changes. Proc. Natl. Acad. Sci. U.S.A. 81, 3751-3755.
34. SHEETZ, M. P. & SINGER, S. J. (1974). Biological membranes as bilayer couples. A molecular mechanism of drugerythrocyte interactions. Proc. Natl. Acad. Sci. U.S.A. 71, 4457-4461.
35. SVETINA, S., BOZIC, B., SONG, J., WAUGH, R. E. & ZEKS, B. (1992). Phospholipid membrane local and nonlocal bending moudili determined by tether formation from aspirated vesicles. In: Springer Series in Physics, Vol. 66, 154-157.
36. TILLEY, L., CRIBIER, S., ROELOFSEN, B., OPDEN KAMP, J. A. F. & VAN DEENEN, L. L. M. (1986). ATP-dependent translocation of amino phospholipids across the human erythrocyte membrane. FEBS Lett. 194, 1-27.
37. VAN MEER, G., GAHMBERG, C. G., OP DEN KAMP, J. A. F. & VAN DEENEN, L. L. M. (1981). Phospholipid distribution in human En (a-) red cell membranes which lack the major sialoglycoprotein glycophorin A. FEBS Lett. 135, 53-55.
38. VERKLEIJ, A. J., ZWAAL, R. F. A., ROELOFSON, B., COMFURIUS, P., KASTELIJN, D. & VAN DEENEN, L. L. M. (1973). The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy. Biochim. Biophys. Acta 323, 178-193.
39. WILLIAMSON, P., BATEMAN, J., KOZARSKY, K., MATTOCKS, K., HERMANOVICZ, N., CHOE, H.-R. & SCHLEGEL, R. A. (1982). Involvement of spectrin in the maintenance of phasestate asymmetry in the erythrocyte membrane. Cell 30, 725-733.
40. ZACHOWSKI, A., FAVRE, E., CRIBIER, S., HERVÉ, P. & DEVAUX, P. F. (1986). Outside-inside translocation of aminophospholipids in the human erythrocyte membrane is mediated by a specific enzyme. Biochemistry 25, 2585-2590.
41. ZACHOWSKI, A. (1993). Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement. Biochem. J. 294, 1-14.