Simultaneous assessment of the hemodynamic, cardiomechanical, and electrophysiological effects of terfenadine on the in vivo canine model

Heart and Vessels

Volumn 13, Issue 2, 1998, Pages 49-57

  Usui, Tatsuya ^a   Sugiyama, Atsushi ^b   Ishida, Yuko ^b   Satoh, Yoshioki ^b   Sasaki, Yasuyuki ^a   Hashimoto, Keitaro ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Monophasic action potential; Potassium channel; Terfenadine; Torsades de pointes

Indexed keywords

HISTAMINE H1 RECEPTOR ANTAGONIST; POTASSIUM; POTASSIUM CHANNEL; TERFENADINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR CONDUCTION; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; FEMALE; HEART ELECTROPHYSIOLOGY; HEART HEMODYNAMICS; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HEART PRELOAD; HEART RATE; HEART REPOLARIZATION; HIS BUNDLE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; TORSADE DES POINTES;

ANALYSIS OF VARIANCE; ANIMALS; CARDIOVASCULAR PHYSIOLOGY; CARDIOVASCULAR SYSTEM; DISEASE MODELS, ANIMAL; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; FEMALE; HEMODYNAMIC PROCESSES; HISTAMINE H1 ANTAGONISTS; INJECTIONS, INTRAVENOUS; MALE; RANDOM ALLOCATION; REFERENCE VALUES; TERFENADINE;

EID: 0032449960     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01744586     Document Type: Article

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