Opposing roles of the Staphylococcus aureus virulence regulators, agr and sar, in triton X-100- and penicillin-induced autolysis

Journal of Bacteriology

Volumn 180, Issue 14, 1998, Pages 3724-3726

  Fujimoto, David F ^a   Bayles, Kenneth W ^a  

^a UNIVERSITY OF IDAHO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFOXITIN; HYDROLASE; IMIPENEM; OXACILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN DERIVATIVE; PEPTIDOGLYCAN; TRITON X 100; VIRULENCE FACTOR;

ANTIBIOTIC SENSITIVITY; ARTICLE; AUTOLYSIS; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; STAPHYLOCOCCUS AUREUS; ZYMOGRAPHY;

ANIMALIA; BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 0032448155     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.14.3724-3726.1998     Document Type: Article

References (19)

1. Archibald, A. R., I. C. Hancock, and C. R. Harwood. 1993. Cell wall structure, synthesis, and turnover, p. 381-410. In A. L. Sonenshein, J. A. Hoch, and R. Losick (ed.). Bacillus subtilis and other gram-positive bacteria. American Society for Microbiology, Washington, D.C.
2. Brunskill, E. W., and K. W. Bayles. 1996. Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus. J. Bacteriol. 178:611-618.
3. Brunskill, E. W., and K. W. Bayles. 1996. Identification of LytSR-regulated genes from Staphylococcus aureus. J. Bacteriol. 178:5810-5812.
4. Foster, S. J. 1995. Molecular characterization and functional analysis of the major autolysin of Staphylococcus aureus 8325/4. J. Bacteriol. 177:5723-5725.
5. Foster, S. J. 1992. Analysis of the autolysins of Bacillus subtilis 168 during vegetative growth and differentiation by using renaturing polyacrylamide gel electrophoresis. J. Bacteriol. 174:464-470.
6. Holtje, J.-V., and E. I. Tuomanen. 1991. The murein hydrolases of Escherichia coli: properties, functions and impact on the course of infections in vivo. J. Gen. Microbiol. 137:441-454.
7. Kuroda, A., Y. Asami, and J. Sekiguchi. 1993. Molecular cloning of a sporulation-specific cell wall hydrolase gene of Bacillus subtilis. J. Bacteriol. 175: 6260-6268.
8. Mani, N., P. Tobin, and R. K. Jayaswal. 1993. Isolation and characterization of autolysis-defective mutants of Staphylococcus aureus created by Tn917-lacZ mutagenesis. J. Bacteriol. 175:1493-1499.
9. Moreillon, P., Z. Markiewicz, S. Nachman, and A. Tomasz. 1990. Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms. Antimicrob. Agents Chemother. 34:33-39.
10. Novick, R. P., H. F. Ross, S. J. Projan, J. Kornblum, B. Kreiswirth, and S. Moghazeh, 1993. Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. EMBO J. 12:3967-3975.
11. Oshida, T., M. Sugai, H. Komatsuzawa, Y. M. Hong, H. Suginaka, and A. Tomasz. 1995. A Staphylococcus aureus autolysin that has an N-acetylmuramoyl-L-alanine amidase domain and an endo-beta-N-acetylglucosaminidase domain: cloning, sequence analysis, and characterization. Proc. Natl. Acad. Sci. USA 92:285-289.
12. Perkins, H. R. 1980. The bacterial autolysins, p. 437-456. In H. J. Rogers, H. R. Perkins, and J. B. Ward (ed.), Microbial cell walls. Chapman and Hall, London, United Kingdom.
13. Piriz-Duran, S., F. H. Kayser, and B. Berger-Bachi. 1996. Impact of sar and agr on methicillin resistance in Staphylococcus aureus. FEMS Microbiol. Lett. 141:255-260.
14. Qoronfleh, M. W., and B. J. Wilkinson. 1986. Effects of growth of methicillin-resistant and -susceptible Staphylococcus aureus in the presence of β-lactams on peptidoglycan structure and susceptibility to lytic enzymes. Antimicrob. Agents Chemother. 29:250-257.
15. Ramadurai, L., and R. K. Jayaswal. 1997. Molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus, J. Bacteriol. 179:3625-3631.
16. Sekiguchi, J., B. Ezaki, K. Kodama, and T. Akamatsu. 1988. Molecular cloning of a gene affecting the autolysin level and flagellation in Bacillus subtilis. J. Gen. Microbiol. 134:1611-1621.
17. Shockman, G. D., and J.-V. Holtje. 1994. Microbial peptidoglycan (murein) hydrolases, p. 131-166. In J.-M. Ghuysen and R. Hakenbeck (ed.), Bacterial cell wall, vol. 27. Elsevier Science B.V., Amsterdam, The Netherlands.
18. Tobin, P. J., N. Mani, and R. K. Javaswal. 1994. Effect of physiological conditions on the autolysis of Staphylococcus aureus strains. Antonie Leeuwenhoek 65:71-78.
19. Ward, J. B., and R. Williamson. 1985. Bacterial autolysins: specificity and function, p. 159-166. in C. Nombela (ed.), Microbial cell wall synthesis and autolysis. Elsevier Science Publishers, Amsterdam, The Netherlands.