Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus

Journal of Bacteriology

Volumn 178, Issue 3, 1996, Pages 611-618

  Brunskill, Eric W ^a   Bayles, Kenneth W ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b Maryland Sea Grant Exten Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLASE; PEPTIDOGLYCAN;

ARTICLE; AUTOLYSIS; BACTERIAL GENE; BACTERIOLYSIS; CELL AGGREGATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TRANSMISSION ELECTRON MICROSCOPY;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 0030049824     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.3.611-618.1996     Document Type: Article

References (53)

1. Albright, L. M., E. Huala, and F. Ausubel. 1989. Prokaryotic signal transduction mediated by sensor and regulator protein pairs. Annu. Rev Genet 23:311-336.
2. Allen, B. L., G. F. Gerlach, and S. Clegg. 1991. Nucleotide sequence and functions of mrk determinants necessary for expression of type 3 fimbriae in Klebsiella pneumoniae J Bacteriol. 193:916-920.
3. Arthur, M., C. Molinas, and P. Courvalin. 1992. The VanR-VanS two-component regulatory system controls synthesis of depsipeptide precursors in Enterococcus faecium BM4147. J Bacteriol. 174:2582-2591.
4. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1991 Current protocols in molecular biology. John Wiley & Sons, New York.
5. Axelsson, L., A. Holck, S. Birkeland, T. Aukrust, and H. Blom. 1993. Cloning and nucleotide sequence of a gene from Lactobacillus sake Lb706 necessary for sakacin A productíon and immunity. Appl Environ. Microbiol. 59:2869-2875.
6. Bayles, K. W. 1993. The use of degenerate, sensor gene-specific, oligodeoxyribonucleotide primers to amplify DNA fragments from Staphylocuccus aureus. Gene 123:99-103
7. Bayles, K. W. 1994. Environmental sensing mechanisms in Staphylococcus aureus. ASM News 60:597-599
8. Bayles, K. W., E. W. Brunskill, L. L. Hruska, S. Huang, J. J. Iandolo, P. A. Pattee, B. K. Smiley, and R. E. Yasbin. 1994. A genetic and molecular characterization of the recA gene from Staphylococcus aureus. Gene 147: 13-20.
9. Berry, A. M., J. C. Paton, and D. Hansman. 1992. Effect of insertional inactivation of the genes encoding pneumolysin and autolysin on the virulence of Streptococcus pneumoniae type 3. Microb Pathog 12:87-93
10. Brunskill, E. W., and K. W. Bayles. Unpublished data.
11. Charles, T. C., and E. W. Nester. 1993 A chromosomally encoded two-component sensory transduction system is required for virulence of Agrobacterium tumefaciens. J. Bacteriol 175:6614-6625
12. Chatterjee, A. N., W. Wong, F. E. Young, and R. W. Gilpin. 1976. Isolation and characterization of a mutant of Staphylococcus aureus deficient in autolytic activity. J. Bacteriol. 125:961-967
13. Deretic, V., R. Dikshit, W. M. Konyeesni, A. M. Chakrabarty, and T. K. Misra. 1989. The algR gene, which regulates mucoidy in Pseudomonas aeruginosa, belongs to a class of environmenaly responsive genes. J. Bacteriol 171: 1278-1283.
14. Devereux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
15. Diaz, E., R. Lopez, and J. L. Garcia. 1992. Role of the major pneumococcal autolysin in the atypical response of a clinical isolate of Streptococcus pneumoniae J. Bacteriol 174:5508-5515.
16. Dyer, D. W., and J. J. Iandolo. 1983. Rapid isolation of DNA from Staphylococcus aureus. Appl. Environ. Microbiol 46:283-285.
17. Gustafson, J. E., B. Berger-Bachi, A. Strassle, and B. J. Wilkinson. 1992. Autolysis of methicillin-resistant and -susceptible Staphylococcus aureus. Antimicrob. Agents Chemother. 36:566-572.
18. Hart, M. E., M. S. Smeltzer, and J. J. Iandolo. 1993. The extracellular protein regulator (xpr) affects exoprotein and agr mRNA levels in Staphylococcus aureus. J Bacteriol 175:7875-7879
19. Iandolo, J. J. 1990. The genetics of staphylococcal toxins and virulence factors, p 399-426. In B. H. Iglewski and V L Clark (ed), Molecular basis of bacterial pathogenesis Academic Press, Inc., New York.
20. Inoue, H., H. Nojima, and H. Okayama. 1990. High efficiency transformation of Escherichia coli with plasmids. Gene 96:23-28.
21. Janzon, L., and S. Arvidson. 1990. The role of the delta-lysin gene (hld) in the regulation of virulence genes by the accessory gene regulator (agr) in Staphylococcus aureus EMBO J. 9:1391-1399.
22. Keller, G. M., R. S. Hanson, and M. S. Bergdoll. 1978. Effect of minerals on staphylococcal enterotoxin B production. Infect. Immun. 20:158-160.
23. Kornblum, J., B. N. Kreiswirth, S. J. Projan, H. Ross, and R. P. Novick. 1990 Agr: a polycistronic locus regulating exoprotein synthesis in Staphylococcus aureus, p. 373-402. In R. P. Novick (ed). Molecular biology of the staphylucocci VCH Publishers, Inc., New York.
24. Kraemer, G. R., and J. J. Iandolo. 1990. High-frequency transformation of Staphylococcus aureus by electroporation. Curr Microbiol. 21:373-376.
25. Kunst, F., M. Devarbouille, T. Msadek, M. Young, C. Mauel, D. Karamata, A. Klier, and G. Rapoport. 1988. Deduced polypeptides encoded by the Bacillus subtilis sacU locus share homology with two-component sensor-regulator systems. J. Bacteriol. 170:5093-5101.
26. Leroux B., M. F. Yanofsky, S. Winans, J. E. Ward, S. F. Ziegler, and E. W. Nester. 1987 Characterization of the virA of Agrobacterium tumefaciens a transcriptional regulator and host range determinant. EMBO J 6:849-856.
27. Lyristis, M., A. E. Bryant, J. Sloan, M. M. Awad, I. T. Nisbet, D. L. Stevens, and J. I. Rood. 1994. Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringens Mol Microbiol. 12:761-777
28. Makino, K., H. Shinagawa, M. Amemura, and A. Nakata. 1986. Nucleotide sequence of the phoR gene, a regulatory gene for the phosphate regulon of Escherichia coli. J. Mol. Biol. 192:549-556.
29. Mani, N., L. M. Baddour, D. Q. Offutt, U. Vijaranakul, M. J. Nadakavukaren, and R. K. Jayaswal. 1994. Autolysis-defective mutant of Staphylococcus aureus: pathological considerations, genetic mapping, and electron microscopic studies. Infect. Immun. 62:1406-1409.
30. Mani, N., P. Tobin, and R. K. Jayaswal. 1993. Isolation and characterization of autolysis-defective mutants of Staphylococcus aureus created by Tn917-lacZ mutagenesis J Bacteriol. 175:1493-1499
31. Mekalanos, J. J. 1992. Environmental signals controlling expression of virulence determinants in bacteria. J. Bacteriol. 174:1-7
32. Miller, J. F., J. J. Mekalanus, and S. Falkow. 1989. Coordinate regulation and sensory transduction in the control of bacterial virulence. Science 243: 916-921.
33. Mizuno, T., E. T. Wurtzel, and M. Inouye. 1982. Cloning of the regulatory genes (ompR and envZ) for the matrix proteins of the Escherichia coli outer membrane. J. Bacteriol. 150:1462-3466
34. Moran, C. P. 1993. RNA polymerase and transcription factors, p 653-667. In A L Sonenshein, J A Hoch, and R. Losick (ed.), Bacillus subtilis and other gram-positive bacteria. American Society for Microbiology, Washington D.C.
35. Novick, R. P. 1990 The staphylococcus as a molecular genetic system, p. 1-37. In R P. Novick (ed.), Molecular biology of the staphylococci. VCH Publishers, Inc., New York.
36. Parkinson, J. S. 1993. Signal transduction schemes of bacteria Cell 73: 857-871.
37. Parkinson, J. S., and E. C. Kofoid. 1992 Communication modules in bacterial signalling proteins. Annu. Rev. Genet. 26:71-112.
38. Peng, H. L., R. P. Novick, B. Kreiswirth, J. Kornblum, and P. Schlievert. 1988. Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus. J. Bacteriol. 170:4365-4372.
39. Qoronfleh, M. W., and B. J. Wilkinson. 1986. Effects of growth of methicillin-resistant and -sensitive Staphylococcus aureus in the presence of β-lactams on peptidoglycan structure and susceptibility to lytic enzymes. Antimicrob Agents Chemother. 29:250-257.
40. Recsei, P., B. Kreiswirth, M. O'Reilly, P. Schlievert, A. Gruss, and R. P. Novick. 1987. Regulation of exoprotein gene expression in Staphylococcus aureus by agr. Mol. Gen. Genet 202:58-61.
41. Saier, J. M. H. 1994. Convergence and divergence in the evolution of transport proteins. BioEssays 16:23-29.
42. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning a laboratory manual. 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
43. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
44. Sarafian, S. K., and S. A. Morse. 1987. Environmental factors affecting toxic shock syndrome toxin-1 (TSST-1) synthesis. J. Med. Microbiol. 24:75-81.
45. Shafer, M. W., and J. J. Iandolo. 1979. Genetics of staphylococcus enterotoxin B in methicillin-resistant isolates of Staphylococcus aureus. Infect. Immun. 25:902-911.
46. Sorokin, A. V., E. Zumstein, V. Azevedo, S. D. Ehrlich, and P. Serror. 1993 The organization of the Bacillus subtilis 168 chromosome region between the spoVA and serA genetic loci, based on sequence data. Mol Microbiol 10: 385-395.
47. Stock, A., T. Chen, D. Welsh, and J. Stock. 1988. CheA protein a control regulator of bacterial chemotaxis belongs to a family of protein that control gene expression in response to changing environmental conditions. Proc Natl. Acad. Sci. USA 85:1403-1407.
48. Stock, J. B., A. J. Ninfa, and A. M. Stock. 1989 Protein phosphorylation and regulation of adaptive responses in bacteria. Mol. Microbiol. 53:450-490.
49. Stock, J. B., A. M. Stock, and J. M. Mottonen. 1990. Signal transduction in bacteria. Nature (London) 344:395-400.
50. Trach, K. A., and J. A. Hoch. 1993 Multisensory activation of the phosphorelay initiating sporulation in Bacillus subtilis, identification and sequence of the protein kinase of the alternate pathway Mol Microbiol 8: 69-79.
51. Walker, J. E., M. Sarste, M. J. Runswick, and N. J. Gay. 1982 Distantly related sequences in the a- and b- subunits of ATP synthase, myosin, kinases, and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO 1:255-264
52. Weinrauch, Y., N. Guillen, and D. A. Dubnau. 1989. Sequence and transcription mapping of Bacillus subtilis competence genes comB and comA, one of which is related to a family of bacterial regulatory determinants. J. Bacteriol 171:5362-5375.
53. Zuker, M., and P. Steigler. 1981 Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids. Res. 9:133-148.