메뉴 건너뛰기




Volumn 124, Issue 6, 1998, Pages 1130-1137

Regulation of interleukin-1β-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by glucocorticoids

Author keywords

Dexamethasone; Human fibroblast like synoviocytes; IL 6; I B

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; CYCLOHEXIMIDE; DNA BINDING PROTEIN; I KAPPA B; INTERLEUKIN 1; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NUCLEAR PROTEIN; PROTEIN SYNTHESIS INHIBITOR; TRANSCRIPTION FACTOR;

EID: 0032446828     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022231     Document Type: Article
Times cited : (27)

References (25)
  • 1
    • 0029914194 scopus 로고    scopus 로고
    • Invasive fibroblast-like synoviocytes in rheumatoid arthritis
    • Firestein, G.S. (1996) Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Rheum. 39, 1781-1790
    • (1996) Arthritis Rheum. , vol.39 , pp. 1781-1790
    • Firestein, G.S.1
  • 2
    • 0029792941 scopus 로고    scopus 로고
    • Cytokine expression and cell activation in inflammatory arthritis
    • Ivashkiv, L.B. (1996) Cytokine expression and cell activation in inflammatory arthritis. Adv. Immunol. 63, 337-376
    • (1996) Adv. Immunol. , vol.63 , pp. 337-376
    • Ivashkiv, L.B.1
  • 3
    • 0025149103 scopus 로고
    • Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinase-1 in rheumatoid human synovial fibroblasts: Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression
    • MacNaul, K.L., Chartrain, N., Lark, M., Tocci, M.J., and Hutchinson, N.I. (1990) Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinase-1 in rheumatoid human synovial fibroblasts: synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression. J. Biol. Chem. 265, 17238-17245
    • (1990) J. Biol. Chem. , vol.265 , pp. 17238-17245
    • MacNaul, K.L.1    Chartrain, N.2    Lark, M.3    Tocci, M.J.4    Hutchinson, N.I.5
  • 4
    • 0029113780 scopus 로고
    • Levels of circulating collagenase, stromelysin-1, and tissue inhibitor of matrix metalloproteinase 1 in patients with rheumatoid arthritis
    • Manicourt, D.-H., Fujimoto, N., Obata, K., and Thonar, E.-M.A. (1995) Levels of circulating collagenase, stromelysin-1, and tissue inhibitor of matrix metalloproteinase 1 in patients with rheumatoid arthritis. Arthritis Rheum. 38, 1031-1039
    • (1995) Arthritis Rheum. , vol.38 , pp. 1031-1039
    • Manicourt, D.-H.1    Fujimoto, N.2    Obata, K.3    Thonar, E.-M.A.4
  • 6
    • 0025668546 scopus 로고
    • Role of cytokines in inflammatory synovitis: The coordinate regulation of intracellular adhesion molecule 1 and HLA class I and class II antigens in rheumatoid synovial fibroblasts
    • Chin, J.E., Winterrowd, G.E., Krzesicki, R.F., and Sanders, M.E. (1990) Role of cytokines in inflammatory synovitis: the coordinate regulation of intracellular adhesion molecule 1 and HLA class I and class II antigens in rheumatoid synovial fibroblasts. Arthritis Rheum. 33, 1776-1786
    • (1990) Arthritis Rheum. , vol.33 , pp. 1776-1786
    • Chin, J.E.1    Winterrowd, G.E.2    Krzesicki, R.F.3    Sanders, M.E.4
  • 8
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira, S., Taga, T., and Kishimoto, T. (1993) Interleukin-6 in biology and medicine. Adv. Immunol. 56, 1-78
    • (1993) Adv. Immunol. , vol.56 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 9
    • 0023942493 scopus 로고
    • Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
    • Houssiau, F.A., Devogelaer, J.P., Damme, J.V., Deuxchaisnes, C.N., and Snick, J.V. (1988) Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum. 31, 784-788
    • (1988) Arthritis Rheum. , vol.31 , pp. 784-788
    • Houssiau, F.A.1    Devogelaer, J.P.2    Damme, J.V.3    Deuxchaisnes, C.N.4    Snick, J.V.5
  • 10
    • 0026527781 scopus 로고
    • Interleukin 6 levels in synovial fluids of patients with different arthritis: Correction with local IgM rheumatoid factor and systemic acute phase protein production
    • Brozik, M., Rosztoczy, I., Meretey, K., Balint, G., Gaal, M., Balogh, Z., Bart, M., Mitusxova, M., Velics, V., and Falus, A. (1992) Interleukin 6 levels in synovial fluids of patients with different arthritis: Correction with local IgM rheumatoid factor and systemic acute phase protein production. J. Rheumatol. 19, 63-68
    • (1992) J. Rheumatol. , vol.19 , pp. 63-68
    • Brozik, M.1    Rosztoczy, I.2    Meretey, K.3    Balint, G.4    Gaal, M.5    Balogh, Z.6    Bart, M.7    Mitusxova, M.8    Velics, V.9    Falus, A.10
  • 11
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-xB and the glucocorticoid receptor
    • Ray, A. and Prefontaine, K.E. (1994) Physical association and functional antagonism between the p65 subunit of transcription factor NF-xB and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 91, 752-756
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 12
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-xB by activated glucocorticoid receptor
    • Scheinman, R.I., Gualberto, A., Jewell, C.M., Cidlowski, J.A., and Baldwin, A.S.J. (1995) Characterization of mechanisms involved in transrepression of NF-xB by activated glucocorticoid receptor. Mol. Cell. Biol. 15, 943-953
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewell, C.M.3    Cidlowski, J.A.4    Baldwin, A.S.J.5
  • 13
    • 0023574619 scopus 로고
    • Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin l in U937 cells
    • Knudsen, P.J., Dinarello, C.A., and Strom, T.B. (1987) Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin l in U937 cells. J. Immunol. 139, 4129-4134
    • (1987) J. Immunol. , vol.139 , pp. 4129-4134
    • Knudsen, P.J.1    Dinarello, C.A.2    Strom, T.B.3
  • 14
    • 0026548427 scopus 로고
    • Glucocorticoids downregulate gene expression of GM-CSF, NAP-2/IL-8, IL-6 but not M-CSF in human fibroblasts
    • Tobler, A., Meier, R., Seitz, M., Dewald, B., Baggiolini, M., and Fey, M.F. (1992) Glucocorticoids downregulate gene expression of GM-CSF, NAP-2/IL-8, IL-6 but not M-CSF in human fibroblasts. Blood 79, 45-51
    • (1992) Blood , vol.79 , pp. 45-51
    • Tobler, A.1    Meier, R.2    Seitz, M.3    Dewald, B.4    Baggiolini, M.5    Fey, M.F.6
  • 15
    • 0020965007 scopus 로고
    • DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo
    • Chandler, V.L., Maler, B.A., and Yamamoto, K.R. (1983) DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Cell 33, 489-499
    • (1983) Cell , vol.33 , pp. 489-499
    • Chandler, V.L.1    Maler, B.A.2    Yamamoto, K.R.3
  • 16
    • 0025780755 scopus 로고
    • Crystallographic analysis ofthe interaction of the glucocorticoid receptor with DNA
    • Luisi, B.F., Xu, W.X., Otwinowski, Z., Freedman, L.P., Yamamoto, K.R., and Sigler, P.B. (1991) Crystallographic analysis ofthe interaction of the glucocorticoid receptor with DNA. Nature 352, 497-505
    • (1991) Nature , vol.352 , pp. 497-505
    • Luisi, B.F.1    Xu, W.X.2    Otwinowski, Z.3    Freedman, L.P.4    Yamamoto, K.R.5    Sigler, P.B.6
  • 17
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IxBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R.I., Cogswell, P.C., Lofquist, A.K., and Baldwin Jr., A.S. (1995) Role of transcriptional activation of IxBα in mediation of immunosuppression by glucocorticoids. Science 270, 283-286
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 18
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibi-tion of NF-xB activity through induction of IxB synthesis
    • Auphan, N., DiDonato, J.A., Rosette, C., Helmberg, A., and Karin, M. (1995) Immunosuppression by glucocorticoids: Inhibi-tion of NF-xB activity through induction of IxB synthesis. Science 270, 286-290
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 19
    • 0025696119 scopus 로고
    • Expression of the interleukin 6 gene in rheumatoid synovial fibroblasts
    • Tan, P.L.J., Farmiloe, S., Yeoman, S., and Watson, J.D. (1990) Expression of the interleukin 6 gene in rheumatoid synovial fibroblasts. J. Rheumatol. 17, 1608-1612
    • (1990) J. Rheumatol. , vol.17 , pp. 1608-1612
    • Tan, P.L.J.1    Farmiloe, S.2    Yeoman, S.3    Watson, J.D.4
  • 20
    • 0025047444 scopus 로고
    • On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer, TATA box, and RNA start site (inr motif) occlusion
    • Ray, A., LaForge, K.S., and Sehgal, P.B. (1990) On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (inr motif) occlusion. Mol. Cell. Biol. 10, 5736-5746
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5736-5746
    • Ray, A.1    Laforge, K.S.2    Sehgal, P.B.3
  • 21
    • 0032571268 scopus 로고    scopus 로고
    • Transcriptional roles of C/EBPβ, NF-xB, and CBF1 in IL-1β-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes
    • Miyazawa, K., Mori, A., Yamamoto, K., and Okudaira, H. (1998) Transcriptional roles of C/EBPβ, NF-xB, and CBF1 in IL-1β-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem. 273, 7620-7627
    • (1998) J. Biol. Chem. , vol.273 , pp. 7620-7627
    • Miyazawa, K.1    Mori, A.2    Yamamoto, K.3    Okudaira, H.4
  • 22
    • 0031886794 scopus 로고    scopus 로고
    • Constitutive transcription of the human IL-6 gene by rheumatoid synoviocytes: Spontaneous activation of NF-xB and CBF1
    • Miyazawa, K., Mori, A., Yamamoto, K., and Okudaira, H. (1998) Constitutive transcription of the human IL-6 gene by rheumatoid synoviocytes: Spontaneous activation of NF-xB and CBF1. Am. J. Pathol. 152, 793-803
    • (1998) Am. J. Pathol. , vol.152 , pp. 793-803
    • Miyazawa, K.1    Mori, A.2    Yamamoto, K.3    Okudaira, H.4
  • 23
    • 0029762995 scopus 로고    scopus 로고
    • Antiproliferative and c-myc mRNA suppressive effects of tranilast on newborn human vascular smooth muscle cells in culture
    • Miyazawa, K., Hamano, S., and Ujiie, A. (1996) Antiproliferative and c-myc mRNA suppressive effects of tranilast on newborn human vascular smooth muscle cells in culture. Br. J. Pharmacol. 118, 915-922
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 915-922
    • Miyazawa, K.1    Hamano, S.2    Ujiie, A.3
  • 25
    • 0022423245 scopus 로고
    • Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
    • Tso, J.Y., Sun, X.-H., Kao, T., Reece, K.S., and Wu, R. (1985) Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 13, 2485-2502
    • (1985) Nucleic Acids Res. , vol.13 , pp. 2485-2502
    • Tso, J.Y.1    Sun, X.-H.2    Kao, T.3    Reece, K.S.4    Wu, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.