Volatile anesthetics significantly suppress central and peripheral mammalian sodium channels

Toxicology Letters

Volumn 100-101, Issue , 1998, Pages 255-263

  Duch, Daniel S ^a   Rehberg, Benno ^a   Vysotskaya, Tatyana N ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Mammalian sodium channels; Suppress; Volatile anesthetics

Indexed keywords

ETHER; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE; PENTOBARBITAL; SODIUM CHANNEL;

ANIMAL CELL; CHO CELL; CONFERENCE PAPER; CRAYFISH; FROG; GIANT AXON; MAMMAL; NONHUMAN; PRIORITY JOURNAL; SQUID;

ANESTHETICS, INHALATION; ANIMALS; CENTRAL NERVOUS SYSTEM; DEPRESSION, CHEMICAL; HUMANS; MAMMALS; PERIPHERAL NERVOUS SYSTEM; SODIUM CHANNEL BLOCKERS;

CEPHALOPODA; MAMMALIA;

EID: 0032445516     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00193-3     Document Type: Conference Paper

References (47)

1. Aldrich, R.W., Corey, D.P., Stevens, C.F., 1983. A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature 306, 436-441.
2. Barres, B.A., Chun, L.L.Y., Corey, D.P., 1989. Glial and neuronal forms of the voltage-dependent sodium channel: characteristics and cell-type distribution. Neuron 2, 1375-1388.
3. Bean, B.B., Shrager, P., Goldstein, D.A., 1981. Modification of sodium and potassium channel gating kinetics by ether and halothane. J. Gen. Phys. 77, 233-253.
4. Berman, M.F., Camardo, R.B., Robinson, R.B., Siegelbaum, S.A., 1989. Single sodium channels from canine ventricular myocytes: voltage dependence and relative rates of activation and inactivation. J. Physiol. (Lond.) 415, 505-531.
5. Berg-Johnsen, J., Langmoen, I.A., 1990. Mechanisms concerned in the direct effect of isoflurane on rat hippocampla and human neocrotical neurones. Brain Res. 507, 28-34.
6. Butterworth, J.F., Raymond, S.A., Roscoe, R.F., 1989. Effects of halothane and enflurane on firing threshold of frog myelinated axons. J. Physiol. 411, 493-516.
7. Cannon, S.C., Brown, R.H., Corey, D.P., 1993. Theoretical reconstruction of myotonia and paralysis caused by incomplete inactivation of sodium channels. Biophys. J. 65, 270-288.
8. Catterall, W.A., 1995. Structure and function of voltage-gated ion channels. Annu. Rev. Biochem. 64, 493-531.
9. Collins, J.G., Kendig, J.J., Mason, P., 1995. Anesthetic actions within the spinal cord: contributions to the state of general anesthesia. TINS 18, 549-553.
10. Condouris, G.A., Goebel, R.H., Brady, T., 1976. Computer simulation of local anesthetic effects using a mathematical model of myelinated nerve. J. Pharmacol. Exp. Ther. 196, 737-745.
11. Franks, N.P., Lieb, W.R., 1994. Molecular and cellular mechanisms of general anaesthesia. Nature 367, 607-614.
12. Frenkel, C., Urban, B.W., 1991. A molecular target site for propofol: voltage-clamp studies on human CNS sodium channels in bilayers. Eur. J. Pharm. 208, 75-79.
13. Frenkel, C., Urban, B.W., 1992. Molecular actions of racemic ketamine on single s odium channels from human brain cortex. Br. J. Anaesth. 69, 292-297.
14. Frenkel, C., Duch, D.S., Recio-Pinto, E., Urban, B.W., 1989. Pentobarbital suppresses human brain sodium channels. Brain Res. Mol. Brain Res. 6, 211-216.
15. Frenkel, C., Duch, D.S., Urban, B.W., 1990. Molecular actions of pentobarbital isomers on sodium channels from human brain cortex. Anesthesia 72, 640-649.
16. Frenkel, C., Duch, D.S., Urban, B.W., 1993. Effects of i.v. anaesthetics on human brain sodium channels. Br. J. Anaesth. 71, 15-24.
17. Fujiwara, N., Higashi, H., Nishi, S., Shimoji, K., Sugita, S., Yoshimura, M., 1988. Changes in spontaneous firing patterns of rat hippocampal neurones induced by volatile anaesthetics. J. Physiol. 402, 155-175.
18. Haydon, D.A., Elliott, J.R., Hendry, B.M., Urban, B.W. 1986. The action of non-ionic anesthetic substances on voltage-gated ion conductances in squid giant axons. In: Molecular and Cellular Mechanisms of Anesthetics. Plenum, New York.
19. Haydon, D.A., Urban, B.W., 1983a. The action of hydrocarbons and carbon-tetrachloride on the sodium current of the squid giant axon. J. Physiol. 338, 435-450.
20. Haydon, D.A., Urban, B.W., 1983b. The action of alcohols and other non-ionic surface active substances on the sodium current of the squid giant axon. J. Physiol. 341, 411-427.
21. Haydon, D.A., Urban, B.W., 1983c. The effects of some inhalation anesthetics on the sodium current of the squid giant axon. J. Physiol. 341, 429-439.
22. 3) pituitary cells. J. Neurosci. 11, 2226-2240.
23. Hille, B. (1992). Ionic Channels of Excitable Membranes, Sinauer Associates, Sunderland, MA.
24. Horn, R., Vandenberg, C.A., 1984. Statistical properties of single sodium channels. J. Gen. Physiol. 84, 505-534.
25. Kendig, J.J., Courtney, K.R., Cohen, E.N., 1979. Anesthetics: molecular correlates of voltage- and frequency-dependent sodium channel block in nerve. J. Pharm. Exp. Ther. 210, 446-452.
26. Kirsch, G.E., Brown, A.M., 1989. Kinetic properties of sodium channels in rat heart and rat brain. J. Gen. Physiol. 93, 85-99.
27. Krnjevic, K., 1991. Cellular mechanisms of anesthesia. Ann. New York Acad. Sci. 625, 1-16.
28. Langmoen, I.A., Larsen, M., Berg-Johnsen, J., 1995. Volatile anaesthetics: cellular mechanisms of action. Eur. J. Anaesthesiol. 12 (1), 51-58.
29. Narahashi, T., 1992. Nerve membrane Na+ channels as targets of insecticides. Trends Pharmacol. Sci. 13, 236-241.
30. MacIver, M.B., Roth, S.H., 1988. Inhalation anesthetics exhibit pathway specific and differential actions on hippocampal synaptic responses in vitro. Br. J. Anaesth. 60, 680-691.
31. MacIver, M.B., Mikulec, B.A., Amagasu, S.M., Monroe, F.A., 1996. Volatile anesthetics depress glutamate transmission via presynaptic actions. Anesthesiology 85, 823-834.
32. Perouansky, M., Kirson, E.D., Yaari, Y., 1996. Halothane blocks synaptic excitation of inhibitory interneurons. Anesthesiology 85, 1431-1438.
33. 3H]batrachotoxinin-A 20-α-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes. Br. J. Pharmacol. 119, 1498-1504.
34. Raymond, S.A., Shin, H.C., Steffensen, S.C., 1991. A role for changes in axonal excitability in general anesthesia. Ann. New York Acad. Sci. 625, 307-310.
35. Rehberg, B., Bennett, E., Xiao, Y.-H., Levinson, S.R., Duch, D.S., 1995. Voltage- and frequency-dependent suppression of brain and muscle sodium channels expressed in a mammalian cell line. Mol. Pharm. 48, 89-97.
36. Rehberg, B., Wartenberg, H.C., Hernandez, A., Duch, D.S., Urban, B.W., 1996a. Differential effects of halothane and pentobarbital on sodium channel function. Anesthesiology 85, A691.
37. Rehberg, B., Xiao, Y.-H., Duch, D.S., 1996b. Central nervous system sodium channels are significantly suppressed at clinical concentrations of volatile anesthetics. Anesthesiology 84, 1223-1233.
38. Richards, C.D., White, A.E., 1975. The actions of volatile anaesthetics on synaptic transmission in the dentate gyrus. J. Physiol. (Lond.) 252, 241-257.
39. Schlame, M., Hemmings, H.C., 1995. Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism. Anesthesiology 82, 1406-1416.
40. Trimmer, J.S., Cooperman, S.S., Tomiko, S.A., et al., 1989. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron 3, 33-49.
41. Urban, B.W., 1993. Differential effects of gaseous and volatile anaesthetics on sodium and potassium channels. Br. J. Anaesth. 71, 25-38.
42. Vysotskaya, T.N., Duch, D.S., 1997a. Sodium channels in peripheral neurons are blocked by halothane and pentobarbital. Biophys. J. 72, A362.
43. Vysotskaya, T.N., Duch, D.S., 1997b. Isoflurane and halothane block sodium chapels in DRG neurons. Soc. Neurosci. Abs. 23, 1474.
44. Vandenberg, C.A., Horn, R., 1984. Inactivation viewed through single sodium channels. J. Gen. Physiol. 84, 535-564.
45. Weiss, J.N., Venkatesh, N., Lamp, S.T., 1992. ATP-sensitive K+ channels and cellular K+ loss in hypoxic and ischaemic mammalian ventricle. J. Physiol. 447, 649-673.
46. West, J.W., Scheuer, T., Maechler, L., Catterall, W.A., 1992. Efficient expression of rat brain type IIA Na+ channel alpha subunits in a somatic cell line. Neuron 8, 59-70.
47. Yoshimura, M., Higashi, H., Fujita, S., Shimoji, K., 1985. Selective depression of hippocampal inhibitory postsynaptic potentials and spontaneous firing by volatile anesthetics. Brain Res. 340, 363-368.