Complex metabolic phenotypes caused by a mutation in yjgF, encoding a member of the highly conserved YER057c/YjgF family of proteins

Journal of Bacteriology

Volumn 180, Issue 24, 1998, Pages 6519-6528

  Enos Berlage, Jodi L ^a   Langendorf, Mark J ^a   Downs, Diana M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOLEUCINE; PYRIMIDINE; THIAMINE;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL METABOLISM; BACTERIAL MUTATION; GENE SEQUENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PENTOSE PHOSPHATE CYCLE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SALMONELLA TYPHIMURIUM; STRAIN DIFFERENCE;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEPTUNIA; PROKARYOTA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0032444814     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.24.6519-6528.1998     Document Type: Article

References (68)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Mjers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Amos, R. H., and G. N. Cohen. 1954. Amino acid utilization in bacterial growth. J. Biochem. 57:338-343.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1997. Current protocols in molecular biology, vol. 2. John Wiley & Sons, Inc., New York, N.Y.
4. Barak, Z., D. M. Chipman, and N. Gollop. 1987. Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria. J. Bacteriol. 169:3750-3756.
5. Blattner, F. R., G. Plunkett III, C. A. Bloch, N. T. Perna, V. Burland, M. Riley, J. Collado-Vides, J. D. Glasner, C. K. Rode, G. F. Majhew, J. Gregor, N. W. Davis, H. A. Kirkpatrick, M. A. Goeden, D. J. Rose, B. Mau, and Y. Shao. 1997. The complete genome sequence of Escherichia coli K-12. Science 277:1453-1474.
6. Bochner, B. R., H. Huang, G. L. Schieven, and B. N. Ames. 1980. Positive selection for loss of tetracycline resistance. J. Bacteriol. 143:926-933.
7. Bresalier, R. S., A. A. Rizzino, and M. Freunlich. 1975. Reduced maximal level of derepression of the isoleucine-valine and leucine enzymes in hisT mutants of Salmonella typhimurium. Nature 253:279-280.
8. Bruni, C. B., V. Colantuoni, L. Sbordone, R. Cortese, and F. Blasi. 1977. Biochemical and regulatory properties of Escherichia coli K-12 hisT mutant. J. Bacteriol. 130:4-10.
9. Bult, C. J., O. White, G. J. Olsen, L. Zhou, R. D. Fleischmann, G. G. Sutton, J. A. Blake, L. M. Fitzgerald, R. A. Clayton, J. D. Gocayne, A. R. Kerlavage, B. A. Dougherry, J.-F. Tomb, M. D. Adams, C. I. Reich, R. Overbeek, E. F. Kirkness, K. G. Weinstock, J. M. Merrick, A. Glodeck, J. L. Scott, N. S. M. Geoghagen, J. F. Weidman, J. L. Fuhrmann, D. Nguyen, T. R. Utterback, J. M. Kelley, J. D. Peterson, P. W. Sadow, M. C. Hann, M. D. Cotton, K. M. Roberts, M. A. Hurst, B. P. Kaine, M. Borodovsky, H.-P. Klenk, C. M. Fraser, H. O. Smith, C. R. Woese, and J. C. Venter. 1996. Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii. Science 273:1058-1073.
10. Cashel, M., D. R. Gentry, V. J. Hernandez, and D. Vinella. 1996. The stringent response, p. 1458-1496. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed., vol. 1. ASM Press, Washington, D.C.
11. Castilho, B. A., P. Olfson, and M. J. Casadaban. 1984. Plasmid insertion mutagenesis and lac gene fusion with mini-Mu bacteriophage transposons. J. Bacteriol. 158:488-495.
12. Ceciliani, F., L. Faotto, A. Negri, I. Colombo, B. Berra, A. Bartorelli, and S. Ronchi. 1996. The primary structure of UK114 tumor antigen. FEBS Lett. 393:147-150.
13. Chavez, S., J. C. Reyes, F. Chauvat, F. J. Florencio, and P. Candau. 1995. The NADP-glutamate dehydrogenase of the cyanobacterium Synechocystis 6803: cloning, transcriptional analysis and disruption of the gdhA gene. Plant Mol. Biol. 28:173-188.
14. Cosloy, S., and E. McFall. 1970. L-Serine-sensitive mutants of Escherichia coli K-12. J. Bacteriol. 103:840-841.
15. Cosloy, S., and E. McFall. 1973. Metabolism of D-serine in Escherichia coli K-12: mechanism of growth inhibition. J. Bacteriol. 114:685-694.
16. Danchin, A., and L. Dondon. 1980. Serine sensitivity of Escherichia coli K 12: partial characterization of a serine resistant mutant that is extremely sensitive to 2-ketobutyrate. Mol. Gen. Genet. 178:155-164.
17. 4]-1-deoxy-D-threo-2-pentulose and incorporation of this sugar in biosynthesis of thiazole by Escherichia coli cells. J. Chem. Soc. Perkin Trans. 1:2131-2137.
18. Davis, R. W., D. Botstein, and J. R. Roth. 1980. Advanced bacterial genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
19. Deckert, G., P. V. Warren, T. Gaasterland, W. G. Young, A. L. Lenox, D. E. Graham, R. Overbeek, M. A. Snead, M. Keller, M. Aujar, R. Huber, R. A. Feldman, J. M. Short, G. J. Olson, and R. V. Swanson. 1998. The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature 392: 353-358.
20. DeMoll, E., and W. Shive. 1985. Determination of the metabolic origin of the sulfur atom in thiamine of Escherichia coli by mass spectrometry. Biochem. Biophys. Res. Commun. 132:217-222.
21. Downs, D. M. 1992. Evidence for a new, oxygen-regulated biosynthetic pathway for the pyrimidine moiety of thiamine in Salmonella typhimurium. J. Bacteriol. 174:1515-1521.
22. Downs, D. M., and L. Petersen. 1994. apbA, a new genetic locus involved in thiamine biosynthesis in Salmonella typhimurium. J. Bacteriol. 176:4858-4864.
23. Downs, D. M., and J. R. Roth. 1991. Synthesis of thiamine in Salmonella typhimurium independent of the purF function. J. Bacteriol. 173:6597-6604.
24. Enos-Berlage, J. L., and D. M. Downs. Biosynthesis of the pyrimidine moiety of thiamine independent of the PurF enzyme (phosphoribosylpyrophosphate amidotransferase) in Salmonella typhimurium: incorporation of stable isotope-labeled glycine and formate. Submitted for publication.
25. Enos-Berlage, J. L., and D. M. Downs. 1996. Involvement of the oxidative pentose phosphate pathway in thiamine biosynthesis in Salmonella typhimurium. J. Bacteriol. 178:1476-1479.
26. Enos-Berlage, J. L., and D. M. Downs. 1997. Mutations in sdh (succinate dehydrogenase genes) alter the thiamine requirement of Salmonella typhimurium. J. Bacteriol. 179:3989-3996.
27. Enos-Berlage, J. L., and D. M. Downs. 1996. Unpublished results.
28. Estramareix, B., and S. David. 1990. Conversion of 5-aminoimidazole ribotide to the pyrimidine of thiamine in enterobacteria: study of the pathway with specifically labeled samples of riboside. Biochim. Biophys. Acta 1035: 154-160.
29. Estramareix, B., and M. Therisod. 1972. Tyrosine as a factor in biosynthesis of the thiazole moiety of thiamine in Escherichia coli. Biochim. Biophys. Acta 273:275-282.
30. Fleischmann, R. D., M. D. Adams, O. White, R. A. Clayton, E. F. Kirkness, A. R. Kerlavage, C. J. Bult, J.-F. Tomb, B. A. Dougherty, J. M. Merrick, J. F. Weidman, C. A. Phillips, T. Spriggs, E. Hedblom, M. D. Cottom, T. R. Utterback, M. C. Hanna, D.T. Nguyen, D. M. Saudek, R. C. Brandon, L. D. Fine, J. L. Fritchman, J. L. Fuhrmann, N. S. M. Geoghagen, C. L. Gnehm, L. A. McDonald, K. V. Small, C. M. Fraser, H. O. Smith, and J. C. Venter. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512.
31. Freiberg, C., R. Fellay, A. Bairoch, W. J. Broughton, A. Rosenthal, and X. Perret. 1997. Molecular basis of symbiosis between Rhizobium and legumes. Nature 387:394-401.
32. Frodyma, M. E., and D. M. Downs. 1998. ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium, is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway. J. Biol. Chem. 273:5572-5576.
33. Frodyma, M. E., and D. M. Downs. 1998. The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium. J. Bacteriol. 180:4757-1759.
34. Gaal, T., and R. Gourse. 1990. Guanosine 3′-diphosphate 5′-diphosphate is not required for growth rate-dependent control of rRNA synthesis in Escherichia coli. Proc. Natl. Acad. Sci. USA 87:5533-5537.
35. Goupil-Feuillerat, N., M. Cocaign-Bousquet, J.-J. Gocon, S. D. Ehrlich, and P. Renault. 1997. Dual role of α-acetolactate decarboxylase in Lactococcus lactis subsp. lactis. J. Bacteriol. 179:6285-6293.
36. Hama, H., T. Kayahara, M. Tsuda, and T. Tsuchiya. 1991. Inhibition of homoserine dehydrogenase I by L-serine in Escherichia coli. J. Biochem. 109: 604-608.
37. Hama, H., Y. Sumita, Y. Kakutani, M. Tsuda, and T. Tsuchiya. 1990. Target of serine inhibition in Escherichia coli. Biochem. Biophys. Res. Commun. 168:1211-1216.
38. Hong, J. S., and B. N. Ames. 1971. Localized mutagenesis of any specific small region of the bacterial chromosome. Proc. Natl. Acad. Sci. USA 68: 3158-3162.
39. Hughes, K. T., and J. R. Roth. 1984. Conditionally transposition-defective derivative of Mu d1 (Amp Lac). J. Bacteriol. 159:130-137.
40. Hughes, K. T., and J. R. Roth. 1985. Directed formation of deletions and duplication using Mud (Ap, Lac). Genetics 109:263-282.
41. Hughes, K. T., and J. R. Roth. 1988. Transitory cis complementation: a method for providing transposition functions to defective transposons. Genetics 119:9-12.
42. Joerger, R. D., M. R. Jacobson, and P. E. Bishop. 1989. Two nifA-like genes required for expression of alternative nitrogenases by Azotobacler vinelandii. J. Bacteriol. 171:3258-3267.
43. Kleckner, J., J. R. Roth, and D. Botstein. 1977. Genetic engineering in vivo using translocatable drug resistant elements. J. Mol. Biol. 116:125-159.
44. Klenk, H. P., R. A. Clayton, J. F. Tomb, O. White, K. E. Nelson, K. A. Ketchum, R. J. Dodson, M. Gwinn, E. K. Hickey, J. D. Peterson, D. L. Richardson, A. R. Derlavage, D. E. Graham, N. C. Kyrpides, R. D. Fleischmann, J. Quackenbush, N. H. Lee, G. G. Sutton, S. Gill, E. F. Kirkness, B. A. Dougherty, K. McKenney, M. D. Adams, B. Loftus, J. C. Venter, et al. 1997. The complete genome sequence of the hyperthermophilic sulphate-reducing archacon Archaeoglobus fulgidus. Nature 390:364-370.
45. LaRossa, R., T. K. Van Dyk, and D. R. Smulski. 1987. Toxic accumulation of α-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium. J. Bacteriol. 169:1372-1378.
46. Levy-Favatier, F., L. Cuisset, B. Nedelec, L. Tichonicky, J. Kruh, and M. Delpech. 1993. Characterization, purification, and cDNA cloning of a rat perchloric-acid-soluble 23-kDa protein present only in liver and kidney. Eur. J. Biochem. 212:665-673.
47. Maloy, S. R., and W. D. Nunn. 1981. Selection for loss of tetracycline resistance by Escherichia coli. J. Bacteriol. 145:1110-1112.
48. Martinez, E., B. Bartolome, and F. de la Cruz. 1988. pACYC184-derived cloning vectors containing the multiple cloning site and lacAa reporter gene of pUC8/9 and pUC18/19 plasmids. Gene 68:159-162.
49. Negre, D., J.-C. Cortay, P. Donini, and A. J. Cozzone. 1989. Relationship between guanosine tetraphosphate and accuracy of translation in Salmonella typhimurium. Biochemistry 28:1814-1819.
50. Newell, P. C., and R. G. Tucker. 1968. Biosynthesis of the pyrimidine moiety of thiamine. Biochem. J. 106:279-287.
51. Newell, P. C., and R. G. Tucker. 1968. Precursors of the pyrimidine moiety of thiamine. Biochem. J. 106:271-277.
52. Ogasawara, N., S. Nakai, and H. Yoshikawa. 1994. Systematic sequencing of the 180 kilobase region of the Bacillus subtilis chromosome containing the replication origin. DNA Res. 1:1-14.
53. Oka, T., H. Tsuji, C. Noda, K. Sakai, Y.-M. Hong, I. Suzuki, S. Munoz, and Y. Natori. 1995. Isolation and characterization of a novel perchloric-acid soluble protein inhibiting cell-free protein synthesis. J. Biol. Chem. 270: 30060-30067.
54. Petersen, L. A., J. L. Enos-Berlage, and D. M. Downs. 1996. Genetic analysis of metabolic crosstalk and its impact on thiamine synthesis in Salmonella typhimurium. Genetics 143:37-44.
55. Rasko, I., and L. Alfoldi. 1971. Biosynthetic L-threonine deaminase as the origin of L-serine sensitivity of Escherichia coli. Eur. J. Biochem. 21:424-427.
56. Rowley, D. 1953. Inhibition of E. coli strains by amino-acids. Nature 171:80-81.
57. Schmiedeknecht, G., C. Kerkhoff, E. Orso, J. Stohr, C. Aslanidis, G. M. Nagy, R. Knuechel, and G. Schmitz. 1996. Isolation and characterization of a 14.5-kDa trichloroacetic-acid-soluble translational inhibitor protein from human monocytes that is upregulated upon cellular differentiation. Eur. J. Biochem. 242:339-351.
58. Schmieger, H. 1972. Phage P22 mutants with increased or decreased transduction abilities. Mol. Gen. Genet. 119:75-88.
59. Smith, D. R., L. A. Doucette-Stamm, C. Deloughery, H. Lee, J. Dubois, T. Aldredge, R. Bashirzadeh, D. Blakely, R. Cook, K. Gilbert, D. Harrison, L. Hoang, P. Keagle, W. Lumm, B. Pothier, D. Qiu, R. Spadafora, R. Vicaire, Y. Wang, J. Wierzbowski, R. Gibson, N. Jiwani, A. Caruso, O. Bush, et al. 1997. Complete genome sequence of Methanobacterium thermoautotrophicum ΔH: functional analysis and comparative genomics. J. Bacteriol. 179: 7135-7155.
60. Stauffer, G. V. 1996. Biosynthesis of serine, glycine, and one-carbon units, p. 506-513. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed., vol. 1. ASM Press, Washington, D.C.
61. Tabor, S. 1990. Expression using the T7 RNA polymerase/promoter system, p. 16.2.1-16.2.11. In P. A. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. C. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. Wiley, New York, N.Y.
62. Tomb, J.-F., O. White, A. R. Kerlavage, R. A. Clayton, G. G. Sutton, R. D. Fleischmann, K. A. Ketchum, H. P. Klenk, S. Gill, B. A. Dougherty, K. Nelson, J. Quackenbush, L. Zhou, E. F. Kirkness, S. Peterson, B. Loftus, D. Richardson, R. Dodson, H. G. Khalak, A. Glodek, K. McKenney, L. M. Fitzegerald, N. Lee, M. D. Adams, E. K. Hickey, D. E. Berg, J. D. Gocayne, T. R. Utterback, J. D. Peterson, J. M. Kelley, M. D. Cotton, J. M. Weidman, C. Fujii, C. Bowman, L. Watthey, E. Wallin, W. S. Hayes, M. Borodovsky, P. D. Karp, H. O. Smith, C. M. Fraser, and J. C. Venter. 1997. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539-547.
63. Umbarger, H. E. 1996. Biosynthesis of the branched-chain amino acids, p. 442-457. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed., vol. 1. ASM Press, Washington, D.C.
64. - mutants. Mol. Gen. Genet. 165:21-30.
65. Uzan, M., and A. Danchin. 1976. A rapid test for the relA mutation in E. coli. Biochem. Biophys. Res. Commun. 69:751-758.
66. Vogel, H. J., and D. M. Bonner. 1956. Acetylornithase of Escherichia coli: partial purification and some properties. J. Biol. Chem. 218:97-106.
67. Way, J. C., M. A. Davis, D. Morisato, D. E. Roberts, and N. Kleckner. 1984. New Tn/0 derivatives for transposon mutagenesis and for construction of lacZ operon fusions by transposition. Gene 32:369-379.
68. Webb, E., F. Febres, and D. M. Downs. 1996. Thiamine pyrophosphate (TPP) negatively regulates transcription of some thi genes of Salmonella typhimurium. J. Bacteriol. 178:2533-2538.