Hematopoietic stem cells as targets for human gene therapy

Cancer Research Therapy and Control

Volumn 7, Issue 1-2, 1998, Pages 19-25

  Dao, Mo A ^a   Nolta, Jan A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLONING VECTOR; GENE THERAPY; GENE TRANSFER; HEMATOPOIETIC STEM CELL; MOUSE; PRIORITY JOURNAL; RETROVIRUS; REVIEW; STEM CELL;

EID: 0032440278     PISSN: 10640525     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (12)

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2. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F.H., Verma, I.M., and Trono, D. (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science, 272, 263-267.
3. Nolta, J.A., Hanley, M.B., Kohn, D.B. (1994). Sustained human hematopoiesis in immunodeficient mice by co-transplantation of marrow stroma expressing human IL-3, analysis of gene transduction of long-lived progenitors. Blood, 83, 3041-3051.
4. Nolta, J.A., Smogorzewska, E.M., and Kohn, D.B. (1995). Analysis of optimal conditions for retroviral-mediated transduction of primitive human hematopoietic cells. Blood, 86, 101-110.
5. - cells. Blood, 88 (10) 645a.
6. Dao, M., Hannum, C.H., Kohn, D.B. and Nolta, J.A. (1997). Flt-3 ligand preserves the clonogenic capacity of primitive human hematopoietic cells during ex vivo retroviral-mediated transduction. Blood, 89, 446.
7. Nolta, J.A., Dao, M.A., Wells, S., Smogorzewska, E.M., and Kohn, D.B. (1996). Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune - deficient mice. Proc. Natl. Acad. Sci. USA., 93, 2414.
8. Kohn, D.B., Weinberg, K.I., Nolta, J.A., Heiss, L.N., Lenarsky, C., Crooks, G.M., Hanley, M.E., Annett, G.A., Brooks, J.S., El-Khoureiy, A., Lawrence, K., Wells, S., Moen, R.C., Bastian, J., Williams-Herman, D.E., Elder, M., Wara, D., Bowen, T., Hershfeld, M.S., Mullen, C.A., Blaese, R.M., and Parkman, R., (1995). Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nature Med., 1, (10) 1017-1023.
9. Dao, M.A., Williams, D.A., Kohn, D.B., and Nolta, J.A. (1996b). High efficiency transduction of human CD34+ progenitors on fibronectin CH-296 verified by clonal integration analysis. Experimental Hematology 24 (9) 1057.
10. v mice. Cell, 42, 71-79.
11. Moritz, T., Patel, V.P., Williams, D.A. (1994). Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors. J. Clin. Invest., 93, 1451.
12. Rill, D.R., Santana, V.M., Roberts, W.M., Nilson, T., Krance, R.A., Heslop, H.E., Moen, R.C., Ihle, J.N., and Brenner, M.K. (1994). Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood, 84, 380-388.