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Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza virus infections
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Hayden FG, Osterhaus ADME, Treanor JJ, Fleming DM, Aoki FY, Nicholson KG, et al. Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza virus infections. N Engl J Med 1997; 337:874-880. This paper reports the first results of zanamivir in acute influenza infection, showing that administration intranasally or by inhalation was well tolerated, and that treatment reduced symptoms of influenza if initiated early.
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(1997)
N Engl J Med
, vol.337
, pp. 874-880
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Hayden, F.G.1
Osterhaus, A.D.M.E.2
Treanor, J.J.3
Fleming, D.M.4
Aoki, F.Y.5
Nicholson, K.G.6
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38
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0013614151
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The effacacy and safety of zanamivir in the treatment of influenza in otherwise healthy and 'high risk' individuals
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24-27 September; San Diego, California, USA [abstract]
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Silagy CA, Campion KJ, Keene O. The effacacy and safety of Zanamivir in the treatment of influenza in otherwise healthy and 'high risk' individuals. 378th Interscience Conference of Antimicrobial Agents and Chemotherapy; 24-27 September 1998; San Diego, California, USA [abstract].
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(1998)
378th Interscience Conference of Antimicrobial Agents and Chemotherapy
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Silagy, C.A.1
Campion, K.J.2
Keene, O.3
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39
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0003206417
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Oral GS4104 successfully reduces duration and severity of naturally acquired influenza
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24-27 September; San Diego, California, USA [abstract]
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Aoki F, Osterhaus A, Rimmelzwaan G, Kinnersley N, Ward P. Oral GS4104 successfully reduces duration and severity of naturally acquired influenza. 38th Interscience Conference of Antimicrobial Agents and Chemotherapy; 24-27 September 1998; San Diego, California, USA [abstract]. This abstract describes the first results from a large phase III study in Europe, Canada and China demonstrating that GS4104 is effective and well tolerated in natural influenza. Benefits were even greater when the therapy was initiated early.
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(1998)
38th Interscience Conference of Antimicrobial Agents and Chemotherapy
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Aoki, F.1
Osterhaus, A.2
Rimmelzwaan, G.3
Kinnersley, N.4
Ward, P.5
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40
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0009553341
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Efficacy of oral GS4104 in treating acute influenza
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24-27 September; San Diego, California, USA [abstract]
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Treanor JJ, Vrooman PS, Hayden FG, Kinnersley N, Ward P, Mills RG. Efficacy of oral GS4104 in treating acute influenza. 38th Interscience Conference of Antimicrobial Agents and Chemotherapy; 24-27 September 1998; San Diego, California, USA [abstract]. The preliminary results of a large phase III US trial, confirming the safety and efficacy of this oral neuraminidase inhibitor.
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(1998)
38th Interscience Conference of Antimicrobial Agents and Chemotherapy
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Treanor, J.J.1
Vrooman, P.S.2
Hayden, F.G.3
Kinnersley, N.4
Ward, P.5
Mills, R.G.6
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41
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0344776285
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Efficacy and safety of Zanamivir in prevention of influenza among healthy adults
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24-27 September; San Diego, California, USA [abstract]
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Monto AS, Robinson DP, Herlocher L, Hinson JM, Elliott M, Keene O. Efficacy and safety of Zanamivir in prevention of influenza among healthy adults. 38th Interscience Conference of Antimicrobial Agents and Chemotherapy; 24-27 September 1998; San Diego, California, USA [abstract].
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(1998)
38th Interscience Conference of Antimicrobial Agents and Chemotherapy
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Monto, A.S.1
Robinson, D.P.2
Herlocher, L.3
Hinson, J.M.4
Elliott, M.5
Keene, O.6
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42
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85038203264
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24-27 September; San Diego, California, USA [abstract]
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Hayden FG, Atmar R. Schilling M, Johnson C, Poretz D, Parr D, et al Safety and efficacy of oral GS4104 in longterm prophylaxis of natural influenza. 38th Interscience Conference of Antimicrobial Agents and Chemotherapy; 24-27 September 1998; San Diego, California, USA [abstract].
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(1998)
38th Interscience Conference of Antimicrobial Agents and Chemotherapy
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Hayden, F.G.1
Atmar, R.2
Schilling, M.3
Johnson, C.4
Poretz, D.5
Parr, D.6
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