Morpholin-2-yl-phosphinic acids are potent GABA(B) receptor antagonists in rat brain

European Journal of Pharmacology

Volumn 362, Issue 1, 1998, Pages 27-34

  Ong, Jennifer ^a   Kerr, David I B ^a   Bittiger, Helmut ^b   Waldmeier, Peter C ^b   Baumann, Peter A ^b   Cooke, Nigel G ^b   Mickel, Stuart J ^b   Froestl, Wolfgang ^b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Baclofen; Brain slice, rat; CGP 56999A; GABA(B) receptor antagonist; Morpholin 2 yl phosphinic acid

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 3 AMINOPROPANEPHOSPHINIC ACID; 3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; CGP 56999A; CGP 71978; CGP 71979; CGP 71982; CGP 76290A; CGP 76291A; MORPHOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING;

ANIMALS; BACLOFEN; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA ANTAGONISTS; MALE; MORPHOLINES; NEOCORTEX; PHOSPHINIC ACIDS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-B;

EID: 0032425787     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00747-X     Document Type: Article

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