cDNA cloning, structural organization, and expression of the sheep NRAMP1 gene

Mammalian Genome

Volumn 9, Issue 12, 1998, Pages 1027-1031

  Bussmann, Vincent ^a   Lantier, Isabelle ^a   Pitel, Frédérique ^a   Patri, Sylvie ^b   Nau, François ^c   Gros, Philippe ^d   Elsen, Jean Michel ^a   Lantier, Frédéric ^a  

^a CEMAGREF   (France)

^b POITIERS UNIVERSITY HOSPITAL   (France)

^c CNRS   (France)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN I; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CHROMOSOME 1; DNA LIBRARY; EXON; GENE EXPRESSION; GENE STRUCTURE; GENETIC SUSCEPTIBILITY; INFECTION RESISTANCE; INTRON; LEISHMANIA; MOLECULAR CLONING; MYCOBACTERIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALMONELLA; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SHEEP; START CODON; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CATTLE; CHICKENS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EXONS; GENE EXPRESSION; GENES; HUMANS; INTRONS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SHEEP; TISSUE DISTRIBUTION; TRANSCRIPTION, GENETIC;

ANIMALIA; CORYNEBACTERINEAE; EUKARYOTA; MYCOBACTERIUM; OVIS ARIES; SALMONELLA;

EID: 0032421547     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900919     Document Type: Article

References (38)

1. Abel L, Sanchez FO, Oberti J, Thuc NV, Hoa LV et al. (1998) Susceptibility to leprosy is linked to the human NRAMP1 gene. J Infect Dis 177, 133-145
2. Atkinson PG, Barton CH (1998) Ectopic expression of Nramp1 in COS-1 cells modulates iron accumulation. FEBS Lett 425, 239-242
3. Bairoch A (1991) PROSITE: A dictionary of sites and patterns in proteins. Nucleic Acids Res 19, 2241-2245
4. Barton CH, White JK, Roach TI, Blackwell JM (1994) NH2-Terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain. J Exp Med 179, 1683-1687
5. Bellamy R, Ruwende C, Corrah T, McAdam KP, Whittle HC et al. (1998) Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 338, 640-644
6. Blackwell JM, Barton CH, White JK, Roach TI, Shaw MA et al. (1994) Genetic regulation of leishmanial and mycobacterial infection: the Lsh/ Ity/Bcg gene story continues. Immunol Lett 43, 99-107
7. Cellier M, Govoni G, Vidal S, Kwan T, Groulx N et al. (1994) Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specitic expression. J Exp Med 180, 1741-1752
8. Cellier M, Prive G, Belouchi A, Kwan T, Rodrigues V et al. (1995) Nramp defines a family of membrane proteins. Proc Natl Acad Sci USA 92, 10089-10093
9. Cellier M, Belouchi A, Gros P (1996) Resistance to intracellular infections: comparative genomic analysis of Nramp. Trends Genet 12, 201-204
10. Cellier M, Shustik C, Dalton W, Rich E, Hu J et al. (1997) Expression of the human NRAMP1 gene in professional primary phagocytes: studies in blood cells and in HL-60 promyelocytic leukemia. J Leukocyte Biol 61, 96-105
11. Chomoczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156-159
12. Desenclos JC, Bouvet P, Pierre V, Brisabois A, Fremy S et al. Epidémiologie des infections à Salmonella: tendances récentes en France et en Europe. Bull Soc Fr Microbiol 11, 208-215
13. Feng J, Li Y, Hashad M. Schurr E, Gros P et al. (1996) Bovine natural resistance associated macrophage protein 1 (NRAMP1) gene. Genome Res 6, 956-964
14. Fleming MD, Trenor CC, Su MA, Foernzler D, Beier DR et al. (1997) Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet 16, 383-386
15. Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD et al. (1998) Nramp2 is mutated in the Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci USA 95, 1148-1153
16. Gautier AV, Lantier I, Lantier F (1998) Mouse susceptibility to infection by the Salmonella abortusovis strain Rv6 is controlled by the Ity/Nramp1 gene and influences the antibody but not the complement responses. Microb Pathog 24, 47-55
17. Govoni G, Vidai S, Cellier M, Lepage P, Malo D et al. (1995) Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages. Genomics 27, 9-19
18. Govoni G, Vidal S, Gauthier S, Skamene E, Malo D et al. (1996) The Bcg/Ity/Lsh locus: genetic transfer of resistance to infections in C57BL/6J mice transgenic for the Nramp1 Gly169 allele. Infect Immun 64, 2923-2929
19. Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero M et al. (1997) Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388, 482-488
20. Hu J, Bumstead N, Skamene E, Gros P, Malo D (1996) Structural organization, sequence, and expression of the chicken NRAMP1 gene encoding the natural resistance-associated macrophage protein 1. DNA Cell Biol 15, 113-123
21. Hu J, Bumstead N, Barrow P, Sebastiani G, Olien L et al. (1997) Resistance to salmonellosis in the chicken is linked to NRAMP1 and TNC. Genome Res 7, 693-704
22. Lantier F, Pitel F, Berthon P, Lantier I, Gautier A et al. (1995) Contrôle génétique de la résistance aux Salmonellae chez les ovins. Renc. rech. Ruminants 2, 311-316
23. Liu XF, Supek F, Nelson N, Culotta VC (1997) Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene. J Biol Chem 272, 11763-11769
24. Malo D, Vogan K, Vidal S, Hu J, Cellier M et al. (1994) Haplotype mapping and sequence analysis of the mouse Nramp gene predicts susceptibility to infection with intracellular parasites. Genomics 23, 51-61
25. Musacchio A, Saraste M, Wilmans M ( 1994) High resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat Struct Biol 1, 546-551
26. Oswald IP, Lantier F, Moutier R, Bertrand MF, Skamene E (1992) Intraperitoneal infection with Salmonella abortusovis is partially controlled by a gene closely linked with the Ity gene. Clin Exp Immunol 87, 373-378
27. Patri S, Nau F (1992) Isolation and sequence of a cDNA coding for the imtnunoglobulin μ chain of the sheep. Mol Immunol 29, 829-836
28. Pinner E, Gruenheid S, Raymond M, Gros P (1997) Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. J Biol Chem 272, 28933-28938
29. Pitel F, Lantier I, Ricquet J, Lanneluc I, Tabet-Aoul K et al. (1994) Cloning, sequencing and localization of an ovine fragment of the NRAMP gene, a candidate for the ITY/BCG/LSH gene. Mamm Genome 5, 834-835
30. Pitel F, Cribiu EP, Yerle M, Lahbib-Mansias Y, Lanneluc I et al. (1995) Regional localization of the ovine NRAMP gene to chromosome 2q41 → q42 by in situ hybridization. Cytogenet Cell Genet 70, 116-118
31. Pitel F, Lantier I, Gellin J, Elsen JM, Lantier F (1996) Two polymorphic microsatellite markers close to ovine NRAMP gene. Anim Genet 27, 60-61
32. Proudfoot NJ, Brownlee GG (1976) 3′ Non-coding region sequences in eukaryotic messenger RNA. Nature 263, 211-214
33. Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 74, 5463-5467
34. Supek F, Supekova L, Nelson H, Nelson N (1996) A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. Proc Natl Acad Sci USA 93, 5105-5110
35. Vidal SM, Malo D, Vogan K, Skamene E, Gros P (1993) Natural resistance to infection with intracellular parasites: isolation of a candidate gene for Bcg. Cell 73, 1-20
36. Vidal S, Gros P, Skamene E (1995a) Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus. J Leukocyte Biol 58, 382-390
37. Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G et al. (1995b) The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 182, 655-666
38. Yu H, Chen JK, Feng S, Dalgarno DC, Brauer AW et al. (1994) Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76, 933-945