Mouse susceptibility to infection by the Salmonella abortusovis vaccine strain Rv6 is controlled by the Ity/Nramp 1 gene and influences the antibody but not the complement responses

Microbial Pathogenesis

Volumn 24, Issue 1, 1998, Pages 47-55

  Gautier, Anne V ^a   Lantier, Isabelle ^a   Lantier, Frederic ^a  

^a CEMAGREF   (France)

Author keywords

Antibody response; Complement; Disease resistance; Mouse; Nramp 1 Ity Lsh Bcg; Salmonella abortusovis

Indexed keywords

BACTERIAL VACCINE; COMPLEMENT; LIVE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BACTERIAL COLONIZATION; CHROMOSOME 1; CONTROLLED STUDY; GENE LOCUS; GENETIC REGULATION; INFECTION RESISTANCE; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; SPLEEN;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR ABORTUSOVIS; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0031910927     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1997.0168     Document Type: Article

References (44)

1. Plant J, Glynn AA. Genetic of resistance to infection with Salmonella typhimurium. J Infect Dis 1976; 133: 72-8.
2. Plant J, Glynn AA. Locating Salmonella resistance gene on mouse chromosome 1. Clin Exp Immunol 1979; 37: 1-6.
3. Taylor BA, O'Brien AD. Position on mouse chromosome 1 of a gene that controls resistance to Salmonella typhimurium. Infect Immun 1982; 36: 1257-60.
4. Hormaeche CE. Genetics of natural resistance to salmonellae in mice. Immunology 1979; 37: 319-27.
5. Bradley DJ, Taylor BA, Blackwell JM Evans EP, Freeman J. Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse. Clin Exp Immunol 1979; 37: 7-14.
6. Plant JE, Blackwell JM, O'Brien AD, Bradley DJ, Glynn AA. Are the Lsh and Ity disease resistance genes at one locus on mouse chromosome 1? Nature 1982; 297: 510-1.
7. Skamene E, Gros P, Forget A, Kongshavn PAL, St Charles C, Taylor BA. Genetic regulation of resistance to intracellular pathogens. Nature 1982; 297: 506-9.
8. Brown IN, Glynn AA, Plant J. Inbred mouse strain resistance to Mycobacterium lepraemurium follows the Ity/Lsh pattern. Immunology 1982; 47: 149-56.
9. Goto Y, Buschman E, Skamene E. Regulation of host resistance to Mycobacterium intracellulare in vivo and in vitro by the Bcg gene. Immunogenetics 1989; 30: 218-21.
10. Appelberg R, Sarmento A. The role of activation and Bcg-encoded macrophage function(s) in the control of Mycobacterium avium infection in mice. Clin Exp Immunol 1990; 80: 324-31.
11. Frelier PF, Templeton JW, Estes M, Whitford HW, Kienle RD. Genetic regulation of Mycobacterium paratuberculosis infection in recombinant inbred mice. Vet Pathol 1990; 27: 362-4.
12. Crocker P., Blackwell J, Bradley DJ. Expression of the natural resistance gene Lsh in resident liver macrophages. Infect Immun 1984; 43: 1033-40.
13. Lissner CR, Swanson RN, O'Brien AD. Genetic control of the innate resistance of mice to Salmonella typhimurium: expression of the Ity gene in peritoneal and splenic macrophages isolated in vitro. J Immunol 1983; 131: 3006-13.
14. Lissner CR, Swanson RN, O'Brien AD. Mouse chromosome 1 Ity locus regulates microbicidal activity of isolated peritoneal macrophages against a diverse group of intracellular and extracellular bacteria. J Immunol 1985; 135: 544-7.
15. Harrington KA, Hormaeche CE. Expression of innate resistance gene Ity in mouse kupffer cells infected with Salmonella typhimurium in vitro. Microb Pathogen 1986; 1: 269-74.
16. Vidal SM, Malo D, Vogan K, Skamene E, Gros P. Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 1993; 73: 469-85.
17. Malo D, Vogan K, Vidal S et al. Haplotype mapping and sequence analysis of the mouse Nramp gene predicts susceptibility to infection with intracellular parasites. Genomics 1994; 23: 51-61.
18. Vidal S, Tremblay M, Govoni G et al. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 1995; 182: 655-66.
19. Vidal S, Gros P, Skamene E. Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus. J Leuk Biol 1995; 58: 382-90.
20. Oswald IP, Lantier F, Moutier R, Bertrand MF, Skamene E. Intraperitoneal infection with Salmonella abortusovis is partially controlled by a gene closely linked with the Ity gene. Clin Exp Immunol 1992; 87: 373-8.
21. Pardon P, Sanchis R, Marly J et al. Experimental ovine salmonellosis (Salmonella abortusovis): pathogenesis and vaccination. Res Microbiol 1990; 141: 945-53.
22. Pardon P, Marly J. Experimental Salmonella abortus ovis infection of normal or primo-infected CD1 mice. Ann Microbiol (Inst Pasteur) 1979; 130B: 21-8.
23. Pitel F, Lantier I, Riquet J, Lanneluc I, Tabet-Aoul K, Saidi-Mehtar N, Lantier F, Gellin J. Cloning, sequencing, and localization of an ovine fragment of the NRAMP gene, a candidate for the ITY/LSH/BCG gene. Mammalian Genome 1994; 5: 834-5.
24. Lantier F, Pardon P, Marly J. Vaccine properties of Salmonella abortus-ovis mutants for streptomycin: screening with a murine model. Infect Immun 1981; 34: 492-7.
25. r) controlling resistance to intracellular parasites. Infect Immun 1983; 40: 1234-5.
26. Lantier F, Pardon P, Marly J. Immunogenicity of a low virulence vaccine strain against Salmonella abortus ovis infection in mice. Infect Immun 1983; 40: 601-7.
27. Fayolle C, O'Callaghan D, Martineau P et al. Genetic control of antibody responses induced against an antigen delivered by recombinant attenuated Salmonella typhimurium. Infect Immun 1994; 62: 4310-9.
28. Matsiota-Barnard P, Mahana W, Avrameas S, Nauciel C. Specific and natural antibody production during Salmonella typhimurium infection in genetically susceptible and resistant mice. Immunology 1993; 79: 375-80.
29. Leslie RGQ. Evaluation of phagocyte function. In: Reeves WG (Ed). Recent Developments in Clinical Immunology, Chap 4. Elsevier Science Publishers, 1984; 77-110.
30. Cinader B, Dubiski S, Wardlaw AC. Distribution, inheritance, and properties of an antigen, MuB1, and its relation to hemolytic complement. J Exp Med 1964; 120: 897-924.
31. Lynch DM, Kay PH, Papadimitriou JM, Grounds MD. Studies on the structure of complement C3 and the stability of C3 derived phagocytic ligands C3b/iC3b in SJL/J and BALB/c mice. Eur Immunogenet 1993; 20: 1-9.
32. Colten HR, Einstein LP. Complement metabolism: cellular and humoral regulation. Transplant Rev 1976; 32: 3-11.
33. Urbach G, Cinader B. Hormonal control of MuB1 concentration. Proc Soc Exp Biol Med 1966; 122: 779-82.
34. Churchill WH, Weintraub RM, Borsos T, Rapp HJ. Mouse complement: the effect of sex hormones and castration on two of the late acting components. J Exp Med 1967; 125: 657-72.
35. Stimson WH. Sex steroïds, steroïd receptors and immunity. In: Berczi I, Kovacs K (Eds). Hormones and Immunity, Chap. 4. Lancaster, UK: MTP Press, 1987; 43-53.
36. Underdown BJ, Schiff JM. Immunoglobulin A: strategic defence initiative at the mucosal surface. Annu Rev Immunol 1986; 4: 389-417.
37. Ferreira P, Soares R, Arala-Chaves M. Susceptibility to infection with Mycobacterium avium is paradoxically correlated with increased synthesis of specific anti-bacterial antibodies. Int Immunol 1991; 3: 445-52.
38. Hussain R, Kifayet A, Chiang TJ. Immunoglobulin G1 (IgG1) and IgG3 antibodies are markers of progressive disease in Leprosy. Infect Immun 1995; 63: 410-5.
39. Xu HR, Tan YY, Hsu HS, Moncure CW, Wang XM. Comparative antibody response to Salmonella antigens in genetically resistant and susceptible mice. Clin Exp Immunol 1993; 91: 73-7.
40. Greenspan NS, Cooper LJN. Intermolecular cooperativity: a clue to why mice have IgG3. Immunol Today 1992; 13: 164-8.
41. Gly169 allele. Infect Immun 1996; 64: 2923-9.
42. Pitel F, Lantier I, Gellin J, Elsen JM, Lantier F. Two polymorphic microsatellite markers close to ovine NRAMP gene. Animal Genetics 1996; 27: 60-1.
43. Bernard S, Lantier I, Laude H, Aynaud JM. Detection of transmissible gastroenteritis coronavirus antigens by a sandwich ELISA technique. Am J Vet Res 1986; 47: 2441-4.
44. Berthon P, Gohin I, Lantier I, Olivier M. Humoral immune response to Salmonella abortusovis in sheep: in vitro induction of an antibody synthesis from either sensitized or unprimed lymph node cells. Vet Immunol Immunopathol 1994; 41: 275-94.