Does erythrocyte infusion improve 3.2-km run performance at high altitude?

European Journal of Applied Physiology and Occupational Physiology

Volumn 79, Issue 1, 1998, Pages 1-6

  Pandolf, Kent B ^a   Young, Andrew J ^a   Sawka, Michael N ^a   Kenney, James L ^a   Sharp, Mark W ^a   Cote, Randy R ^a   Freund, Beau J ^a   Valeri, C Robert ^b  

^a U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood doping; Endurance exercise; Heart rate; Hypoxia; Perceived exertion

Indexed keywords

SODIUM CHLORIDE;

ADULT; AGE; ALTITUDE; ARTICLE; BLOOD AUTOTRANSFUSION; BODY SIZE; CONTROLLED STUDY; ENDURANCE; ERYTHROCYTE; EXERCISE; FITNESS; HEART RATE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RUNNING;

ACCLIMATIZATION; ADULT; ALTITUDE; BLOOD TRANSFUSION, AUTOLOGOUS; BODY COMPOSITION; ERYTHROCYTE TRANSFUSION; HUMANS; MALE; OXYGEN CONSUMPTION; RUNNING;

EID: 0032421387     PISSN: 03015548     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004210050465     Document Type: Article

References (31)

1. Borg G (1970) Perceived exertion as an indicator of somatic stress. Scand J Rehabil Med 2:92-98
2. Brien A, Simon T (1987) The effects of red blood cell infusion on 10-km race time. J Am Med Assoc 257:2761-2765
3. Brien A, Harris R, Simon T (1989) The effects of autologous infusion of 400 ml red blood cells on selected haematological parameters and 1,500 m race time in highly trained runners. Bahrain Med Bull 11:6-16
4. Buick F, Gledhill N, Froese A, Spriet L, Meyers E (1980) Effect of induced erythrocythemia on aerobic work capacity. J Appl Physiol 48:636-642
5. Fulco C, Cymerman A (1988) Human performance and acute hypoxia. In: Pandolf K, Sawka M, Gonzalez R (eds) Human performance physiology and environmental medicine at terrestrial extremes. Benchmark, Indianapolis, pp 467-495
6. Gale G, Torre-Bueno J, Moon R, Saltzman H, Wagner P (1985) Ventilation-perfusion inequality in normal humans during exercise at sea level and simulated altitude. J Appl Physiol 58:978-988
7. Goforth H, Campbell N, Hodgdon J, Sucec A (1982) Hematologic parameters of trained distance runners following induced erythrocythemia Med Sci Sports Exerc 14:174
8. Grover R, Weil J, Reeves J (1986) Cardiovascular adaptations to exercise at high altitude. In: Pandolf K (ed) Exercise and sport sciences reviews. Macmillan, New York, pp 269-302
9. Horstman D, Weiskopf R, Jackson R (1980) Work capacity during 3-week sojourn at 4300 m: effects of relative polycythemia. J Appl Physiol 49:311-318
10. Knapik J (1989) The army physical fitness test (APFT): a review of the literature. Mil Med 154:326-329
11. Mello R, Murphy M, Vogel J (1988) Relationship between a two mile run for time and maximal oxygen uptake. J Appl Sport Sci Res 2:9-12
12. Muza S, Sawka M, Young A, Dennis R, Gonzalez R, Martin J, Pandolf K, Valeri C (1987) Elite special forces: physiological description and ergogenic influence of blood reinfusion. Aviat Space Environ Med 58:1001-1004
13. Pace N, Lozner E, Consolazio W, Pitts G, Pecora L (1947) The increase in hypoxia tolerance of normal men accompanying the polycythemia induced by transfusion of erythrocytes. Am J Physiol 148:152-163
14. Pandolf K (1983) Advances in the study and application of perceived exertion. In: Terjung R (ed) Exercise and sport sciences reviews. Franklin Institute, Philadelphia, pp 118-158
15. Pandolf K (1993) Importance of environmental factors for exercise testing and exercise prescription. In: Skinner J (ed) Exercise testing and exercise prescription for special cases. Lea & Febiger, Philadelphia, pp 87-109
16. Pandolf K, Gange R, Latzka W, Blank I, Kraning K, Gonzalez R (1992) Human thermoregulatory responses during heat exposure after artificially induced sunburn. Am J Physiol 262:R610-R616
17. Robertson R, Gilcher R, Metz K, Skrinar G, Allison T, Bahnson H, Abbott R, Becker R, Falkel J (1982) Effect of induced erythrocythemia on hypoxia tolerance during physical exercise. J Appl Physiol 53:490-495
18. Robertson R, Gilcher R, Metz K, Caspersen C, Allison T, Abbott R, Skrinar G, Krause J, Nixon P (1988) Effect of simulated altitude erythrocythemia in women on hemoglobin flow rate during exercise. J Appl Physiol 64:1644-1649
19. Sawka M, Young A (1989) Acute polycythemia and human performance during exercise and exposure to extreme environments. In: Pandolf K (ed) Exercise and sport sciences reviews. Williams & Wilkins, Baltimore, pp 265-293
20. Sawka M, Dennis R, Gonzalez R, Young A, Muza S, Martin J, Wenger C, Francesconi R, Pandolf K, Valeri C (1987) Influence of polycythemia on blood volume and thermoregulation during exercise-heat stress. J Appl Physiol 62:912-918
21. Sawka M, Gonzalez R, Young A, Muza S, Pandolf K, Latzka W, Dennis R, Valeri C (1988) Polycythemia and hydration: effects on thermoregulation and blood volume during exercise-heat stress. Am J Physiol 255:R456-R463
22. Sawka M, Young A, Rock P, Lyons T, Boushel R, Freund B, Muza S, Dennis R, Pandolf K, Valeri C (1996) Altitude acclimatization and blood volume: effects of exogenous erythrocyte volume expansion. J Appl Physiol 81:636-642
23. Spriet L (1991) Blood doping and oxygen transport. In: Lamb D, Williams M (eds) Perspectives in exercise science and sports medicine volume 4: ergogenics-enhancement of performance in exercise and sports. Brown & Benchmark, Ann Arbor, pp 213-248
24. Torre-Bueno J, Wagner P, Saltzman A, Gale G, Moon R (1985) Diffusion limitation in normal humans during exercise at sea level and simulated altitude. J Appl Physiol 58:989-995
25. Valeri C (1976) Blood banking and the use of frozen blood products. CRC Press, Cleveland
26. Valeri C (1982) New developments in red blood cell preservation using liquid and freezing procedures. J Clin Lab Auto 2:425-439
27. Wagner P, Gale G, Moon R, Torre-Bueno J, Stolp B, Saltzman H (1986) Pulmonary gas exchange in humans exercising at sea level and simulated altitude. J Appl Physiol 61:260-270
28. Williams M, Wesseldine S, Somma T, Schuster R (1981) The effect of induced erythrocythemia upon 5-mile treadmill run time. Med Sci Sports Exerc 13:169-175
29. Young A (1990) Energy substrate utilization during exercise in extreme environments. In: Pandolf K, Holloszy J (eds) Exercise and sport sciences reviews. Williams & Wilkins, Baltimore, pp 65-117
30. Young A, Sawka M, Epstein Y, DeChristofano B, Pandolf K (1987) Cooling different body surfaces during upper and lower body exercise. J Appl Physiol 63:1218-1223
31. 2max at high altitude. J Appl Physiol 81:252-259