메뉴 건너뛰기




Volumn 11, Issue 2, 1998, Pages 447-460

Heparin-induced thrombocytopenia: Diagnostic tests and biological mechanisms

Author keywords

Antibodies; Complexes; Heparin; Mechanisms; Platelet factor 4; Thrombocytopenia; Thrombosis

Indexed keywords

HEPARIN; THROMBOCYTE FACTOR 4;

EID: 0032417169     PISSN: 09503536     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0950-3536(98)80060-7     Document Type: Article
Times cited : (12)

References (73)
  • 1
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia
    • Amiral J Bridey F Dreyfus M Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia Thrombosis and Haemostasis 68 1992 95 96
    • (1992) Thrombosis and Haemostasis , vol.68 , pp. 95-96
    • Amiral, J1    Bridey, F2    Dreyfus, M3
  • 2
    • 0028854433 scopus 로고
    • Antibodies to macromolecular platelet factor 4 heparin complexes in heparin induced thrombocytopenia: a study of 44 cases
    • Amiral J Bridey F Wolf M Antibodies to macromolecular platelet factor 4 heparin complexes in heparin induced thrombocytopenia: a study of 44 cases Thrombosis and Haemostasis 73 1995 21 28
    • (1995) Thrombosis and Haemostasis , vol.73 , pp. 21-28
    • Amiral, J1    Bridey, F2    Wolf, M3
  • 3
    • 8944247264 scopus 로고    scopus 로고
    • Presence of auto-antibodies to interleukin-8 or neutrophil activating peptide-2 in patients with heparin-associated thrombocytopenia
    • Amiral J Marfaing-Koka A Wolf M Presence of auto-antibodies to interleukin-8 or neutrophil activating peptide-2 in patients with heparin-associated thrombocytopenia Blood 88 1996 410 416
    • (1996) Blood , vol.88 , pp. 410-416
    • Amiral, J1    Marfaing-Koka, A2    Wolf, M3
  • 4
    • 0029887360 scopus 로고    scopus 로고
    • Generation of antibodies to heparin-PF4 complexes without thrombocytopenia in patients treated with unfractionated or low molecular weight heparin
    • Amiral J Peynaud-Debayle E Wolf M Generation of antibodies to heparin-PF4 complexes without thrombocytopenia in patients treated with unfractionated or low molecular weight heparin American Journal of Hematology 52 1996 90 95
    • (1996) American Journal of Hematology , vol.52 , pp. 90-95
    • Amiral, J1    Peynaud-Debayle, E2    Wolf, M3
  • 5
    • 0029878458 scopus 로고    scopus 로고
    • Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia
    • Amiral J Wolf M Fischer AM Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia British Journal of Haematology 92 1996 954 959
    • (1996) British Journal of Haematology , vol.92 , pp. 954-959
    • Amiral, J1    Wolf, M2    Fischer, AM3
  • 6
    • 0030980765 scopus 로고    scopus 로고
    • Absence of cross-reactivity of SR 90107A/ORG 31540 pentasaccharide with antibodies to heparin-PF4 complexes developed in heparin-induced thrombocytopenia
    • Amiral J Lormeau JC Marfaing-Koka A Absence of cross-reactivity of SR 90107A/ORG 31540 pentasaccharide with antibodies to heparin-PF4 complexes developed in heparin-induced thrombocytopenia Blood Coagulation and Fibrinolysis 8 1997 114 117
    • (1997) Blood Coagulation and Fibrinolysis , vol.8 , pp. 114-117
    • Amiral, J1    Lormeau, JC2    Marfaing-Koka, A3
  • 7
    • 0028924145 scopus 로고
    • The Fc receptor for immunoglobulin G (FcγRII) on human platelets
    • Anderson CL Chacko GW Osborne JM Brandt JT The Fc receptor for immunoglobulin G (FcγRII) on human platelets Seminars in Thrombosis and Hemostasis 21 1995 1 9
    • (1995) , pp. 1-9
    • Anderson, CL1    Chacko, GW2    Osborne, JM3    Brandt, JT4
  • 8
    • 1842322498 scopus 로고
    • Characterization of antibody subclass specificity and antigenic determinants in heparin-associated thrombocytopenia (HAT)
    • Arepally G Poncz M McKenzie SE Cines D Characterization of antibody subclass specificity and antigenic determinants in heparin-associated thrombocytopenia (HAT) Blood 84 1994 189a
    • (1994) Blood , vol.84 , pp. 189a
    • Arepally, G1    Poncz, M2    McKenzie, SE3    Cines, D4
  • 9
    • 0029591810 scopus 로고
    • Comparison of PF4/heparin ELISA assay with 14C-serotonin release assay in the diagnosis of heparin induced thrombocytopenia
    • Arepally G Reynolds C Tomaski A Comparison of PF4/heparin ELISA assay with 14C-serotonin release assay in the diagnosis of heparin induced thrombocytopenia American Journal of Clinical Pathology 104 1995 648 654
    • (1995) American Journal of Clinical Pathology , vol.104 , pp. 648-654
    • Arepally, G1    Reynolds, C2    Tomaski, A3
  • 10
    • 0031033922 scopus 로고    scopus 로고
    • FcγRIIA H/R131 polymorphism, subclass-specific IgG anti-heparin/platelet factor 4 antibodies and clinical course in patients with heparin-induced thrombocytopenia and thrombosis
    • 131 polymorphism, subclass-specific IgG anti-heparin/platelet factor 4 antibodies and clinical course in patients with heparin-induced thrombocytopenia and thrombosis Blood 89 1997 370 375
    • (1997) Blood , vol.89 , pp. 370-375
    • Arepally, G1    McKenzie, SE2    Jiang, X-M3
  • 11
    • 0028785696 scopus 로고
    • Platelets prime PMN via released PF4: mechanism of priming and synergy with GM-CSF
    • Aziz KA Cawley JC Zulel M Platelets prime PMN via released PF4: mechanism of priming and synergy with GM-CSF British Journal of Haematology 91 1995 846 853
    • (1995) British Journal of Haematology , vol.91 , pp. 846-853
    • Aziz, KA1    Cawley, JC2    Zulel, M3
  • 12
    • 16944364063 scopus 로고    scopus 로고
    • Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery
    • Bauer TL Arepally G Konkle BA Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery Circulation 95 1997 1242 1246
    • (1997) Circulation , vol.95 , pp. 1242-1246
    • Bauer, TL1    Arepally, G2    Konkle, BA3
  • 13
    • 0027163978 scopus 로고
    • Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies
    • Boshkov LK Warkentin TE Hayward CPM Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies British Journal of Haematology 84 1993 322 328
    • (1993) British Journal of Haematology , vol.84 , pp. 322-328
    • Boshkov, LK1    Warkentin, TE2    Hayward, CPM3
  • 14
    • 0027065097 scopus 로고
    • Structure and function of platelet-derived cytokines of the β-thromboglobulin/interleukin 8 family
    • Brandt E Flad HD Structure and function of platelet-derived cytokines of the β-thromboglobulin/interleukin 8 family Platelets 3 1992 295 305
    • (1992) Platelets , vol.3 , pp. 295-305
    • Brandt, E1    Flad, HD2
  • 15
    • 0029417137 scopus 로고
    • On the role of platelet FcγRIIa phenotype in heparin-induced thrombocytopenia
    • Brandt J Isenhgart CE Osborne JM On the role of platelet FcγRIIa phenotype in heparin-induced thrombocytopenia Thrombosis and Haemostasis 74 1995 1564 1572
    • (1995) Thrombosis and Haemostasis , vol.74 , pp. 1564-1572
    • Brandt, J1    Isenhgart, CE2    Osborne, JM3
  • 16
    • 0028871912 scopus 로고
    • Single amino acid mutation of Fcγ receptor is associated with the development of heparin-induced thrombocytopenia
    • Burgess JK Lindeman R Chesterman CN Chong BH Single amino acid mutation of Fcγ receptor is associated with the development of heparin-induced thrombocytopenia British Journal of Haematology 91 1995 761 766
    • (1995) British Journal of Haematology , vol.91 , pp. 761-766
    • Burgess, JK1    Lindeman, R2    Chesterman, CN3    Chong, BH4
  • 17
    • 85088325394 scopus 로고
    • Evolution of antibodies anti-PF4/heparin in a patient with a history of heparin induced thrombocytopenia reexposed to heparin
    • Cadroy Y Amiral J Raynaud H Evolution of antibodies anti-PF4/heparin in a patient with a history of heparin induced thrombocytopenia reexposed to heparin Thrombosis and Haemostasis 72 1994 782 786
    • (1994) Thrombosis and Haemostasis , vol.72 , pp. 782-786
    • Cadroy, Y1    Amiral, J2    Raynaud, H3
  • 19
    • 0024555819 scopus 로고
    • The three-dimensional structure of bovine platelet factor 4 at 3.0-Å resolution
    • St Charles R Walz DA Edwards FP The three-dimensional structure of bovine platelet factor 4 at 3.0-Å resolution Journal of Biological Chemistry 264 1989 2092 2099
    • (1989) Journal of Biological Chemistry , vol.264 , pp. 2092-2099
    • St Charles, R1    Walz, DA2    Edwards, FP3
  • 20
    • 0028285464 scopus 로고
    • Proteinases and cytokines in neutrophil and platelet interactions in vitro. Possible relevance to the adult respiratory distress syndrome
    • Chignard M Renesto P Proteinases and cytokines in neutrophil and platelet interactions in vitro. Possible relevance to the adult respiratory distress syndrome Annals of the New York Academy of Sciences 725 1994 309 322
    • (1994) Annals of the New York Academy of Sciences , vol.725 , pp. 309-322
    • Chignard, M1    Renesto, P2
  • 21
    • 0024601853 scopus 로고
    • Heparin-induced thrombocytopenia: studies with a new low molecular weight heparinoid, Org 10172
    • Chong BH Ismail F Cade J Heparin-induced thrombocytopenia: studies with a new low molecular weight heparinoid, Org 10172 Blood 73 1989 1592 1596
    • (1989) Blood , vol.73 , pp. 1592-1596
    • Chong, BH1    Ismail, F2    Cade, J3
  • 22
    • 0027413887 scopus 로고
    • The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced thrombocytopenia
    • Chong BH Burgess J Ismail F The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced thrombocytopenia Thrombosis and Haemostasis 69 1993 344 350
    • (1993) Thrombosis and Haemostasis , vol.69 , pp. 344-350
    • Chong, BH1    Burgess, J2    Ismail, F3
  • 23
    • 0027395842 scopus 로고
    • Increased expression of platelet IgG Fc receptors in immune heparin induced thrombocytopenia
    • Chong BH Pilgrim RL Cooley MA Chesterman CN Increased expression of platelet IgG Fc receptors in immune heparin induced thrombocytopenia Blood 81 1993 988 993
    • (1993) Blood , vol.81 , pp. 988-993
    • Chong, BH1    Pilgrim, RL2    Cooley, MA3    Chesterman, CN4
  • 24
    • 0023109003 scopus 로고
    • Immune endothelial-cell injury in heparin-associated thrombocytopenia
    • Cines DB Tomaski A Tannenbaum S Immune endothelial-cell injury in heparin-associated thrombocytopenia New England Journal of Medicine 316 1987 581 589
    • (1987) New England Journal of Medicine , vol.316 , pp. 581-589
    • Cines, DB1    Tomaski, A2    Tannenbaum, S3
  • 26
    • 0021327303 scopus 로고
    • Critical ischemia during heparin-induced thrombocytopenia. Treatment by intra-arterial streptokinase
    • Fiessinger JN Aiach M Roncato M Critical ischemia during heparin-induced thrombocytopenia. Treatment by intra-arterial streptokinase Thrombosis Research 33 1984 235 238
    • (1984) Thrombosis Research , vol.33 , pp. 235-238
    • Fiessinger, JN1    Aiach, M2    Roncato, M3
  • 27
    • 0016668496 scopus 로고
    • Heparin-induced thrombocytopenia: confirmation of diagnosis with in vitro methods
    • Fratantoni JC Pollet R Gralnick HR Heparin-induced thrombocytopenia: confirmation of diagnosis with in vitro methods Blood 45 1975 395 401
    • (1975) Blood , vol.45 , pp. 395-401
    • Fratantoni, JC1    Pollet, R2    Gralnick, HR3
  • 29
    • 0028335456 scopus 로고
    • Laboratory diagnosis of heparin associated thrombocytopenia and comparison of platelet aggregation test, heparin induced platelet activation test, and platelet factor 4/heparin enzyme linked immunosorbent assay
    • Greinacher A Amiral J Dummel V Laboratory diagnosis of heparin associated thrombocytopenia and comparison of platelet aggregation test, heparin induced platelet activation test, and platelet factor 4/heparin enzyme linked immunosorbent assay Transfusion 34 1994 381 385
    • (1994) Transfusion , vol.34 , pp. 381-385
    • Greinacher, A1    Amiral, J2    Dummel, V3
  • 30
    • 0028347109 scopus 로고
    • Heparin associated thrombocytopenia: the effects of various intravenous IgG preparations on antibody mediated platelet activation: a possible new indication for high dose I.V. IgG
    • Greinacher A Liebenhoff U Kiefel V Heparin associated thrombocytopenia: the effects of various intravenous IgG preparations on antibody mediated platelet activation: a possible new indication for high dose I.V. IgG Thrombosis and Haemostasis 71 1994 641 645
    • (1994) Thrombosis and Haemostasis , vol.71 , pp. 641-645
    • Greinacher, A1    Liebenhoff, U2    Kiefel, V3
  • 31
    • 0028014541 scopus 로고
    • Heparin associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular pF4-Heparin complex as the major antigen
    • Greinacher A Pötzch B Amiral J Heparin associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular pF4-Heparin complex as the major antigen Thrombosis and Haemostasis 71 1994 247 251
    • (1994) Thrombosis and Haemostasis , vol.71 , pp. 247-251
    • Greinacher, A1    Pötzch, B2    Amiral, J3
  • 32
    • 0029086769 scopus 로고
    • Characterization of the structural requirements for a carbonhydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thromboctopenia
    • Greinacher A Alban S Dummel V Characterization of the structural requirements for a carbonhydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thromboctopenia Thrombosis and Haemostasis 74 1995 886 892
    • (1995) Thrombosis and Haemostasis , vol.74 , pp. 886-892
    • Greinacher, A1    Alban, S2    Dummel, V3
  • 33
    • 0027180316 scopus 로고
    • Further evidence that alpha-granule components such as platelet factor 4 are involved in platelet-IgG-heparin interactions during heparin-associated thrombocytopenia
    • Gruel Y Boizard-Boval B Wautier JL Further evidence that alpha-granule components such as platelet factor 4 are involved in platelet-IgG-heparin interactions during heparin-associated thrombocytopenia Thrombosis and Haemostasis 70 1993 375
    • (1993) Thrombosis and Haemostasis , vol.70 , pp. 375
    • Gruel, Y1    Boizard-Boval, B2    Wautier, JL3
  • 34
    • 0026320692 scopus 로고
    • Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis
    • Gruel Y Lermusiaux P Lang M Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis Annals of Vascular Surgery 5 1991 552 555
    • (1991) Annals of Vascular Surgery , vol.5 , pp. 552-555
    • Gruel, Y1    Lermusiaux, P2    Lang, M3
  • 35
    • 85113051746 scopus 로고
    • Heparin-associated thrombosis despite normal platelet counts
    • Hach-Wunderle V Kainer K Krug B Heparin-associated thrombosis despite normal platelet counts Lancet 344 1994 469 470
    • (1994) Lancet , vol.344 , pp. 469-470
    • Hach-Wunderle, V1    Kainer, K2    Krug, B3
  • 37
    • 0025255513 scopus 로고
    • The effect of molecular weight on heparin binding to platelets
    • Horne McDK III Chao ES The effect of molecular weight on heparin binding to platelets British Journal of Haematology 74 1990 306 312
    • (1990) British Journal of Haematology , vol.74 , pp. 306-312
    • Horne, McDK1    Chao, ES2
  • 39
    • 0020287248 scopus 로고
    • Heparin-associated thrombocytopenia. In vitro effects of different molecular weight heparin fractions
    • Huisse MC Guillin MC Bezeaud Z Heparin-associated thrombocytopenia. In vitro effects of different molecular weight heparin fractions Thrombosis Research 27 1982 485 490
    • (1982) Thrombosis Research , vol.27 , pp. 485-490
    • Huisse, MC1    Guillin, MC2    Bezeaud, Z3
  • 40
    • 0027055259 scopus 로고
    • Pathophysiology of heparin-induced thrombocytopenia
    • Kelton J Pathophysiology of heparin-induced thrombocytopenia British Journal of Haematology 82 1992 778 784
    • (1992) British Journal of Haematology , vol.82 , pp. 778-784
    • Kelton, J1
  • 41
    • 0023710994 scopus 로고
    • Heparin induced thrombocytopenia: laboratory studies
    • Kelton JG Sheridan D Santos A Heparin induced thrombocytopenia: laboratory studies Blood 72 1988 925 930
    • (1988) Blood , vol.72 , pp. 925-930
    • Kelton, JG1    Sheridan, D2    Santos, A3
  • 42
    • 0028243705 scopus 로고
    • Immunoglobulin G from patients with heparin induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • Kelton G Smith JW Warkentin TE Immunoglobulin G from patients with heparin induced thrombocytopenia binds to a complex of heparin and platelet factor 4 Blood 83 1994 3232 3239
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, G1    Smith, JW2    Warkentin, TE3
  • 43
    • 0029948429 scopus 로고    scopus 로고
    • Serglycin-binding proteins in activated macrophages and platelets
    • Kolset SO Mann DM Uhlin-Hansen L Serglycin-binding proteins in activated macrophages and platelets Journal of Leucocyte Biology 59 1996 545 554
    • (1996) Journal of Leucocyte Biology , vol.59 , pp. 545-554
    • Kolset, SO1    Mann, DM2    Uhlin-Hansen, L3
  • 44
    • 0026577426 scopus 로고
    • Further evidence that heparin dependent thrombocytopenia may result from Fc receptor-mediated interactions
    • Laroche J Clofent-Sanchez G Jallu V Further evidence that heparin dependent thrombocytopenia may result from Fc receptor-mediated interactions Nouvelle Revue Française d'Hematologie 34 1992 111 121
    • (1992) Nouvelle Revue Française d'Hematologie , vol.34 , pp. 111-121
    • Laroche, J1    Clofent-Sanchez, G2    Jallu, V3
  • 45
    • 0028947206 scopus 로고
    • Heparin and streptokinase-dependent platelet-activating immunoglobulin G: mechanism and diagnosis
    • Lecompte T Stieltjes N Shao-kai L Heparin and streptokinase-dependent platelet-activating immunoglobulin G: mechanism and diagnosis Seminars in Thrombosis and Hemostasis 21 1995 95 105
    • (1995) , pp. 95-105
    • Lecompte, T1    Stieltjes, N2    Shao-kai, L3
  • 46
    • 0023506519 scopus 로고
    • Tests d'agrégation plaquettaire dans 26 cas de thrombopénies induites par l'héparine (TIH)
    • Lecrubier C Lecompte T Potevin F Tests d'agrégation plaquettaire dans 26 cas de thrombopénies induites par l'héparine (TIH) Journal des Maladies Vasculaires 12 1987 128 132
    • (1987) Journal des Maladies Vasculaires , vol.12 , pp. 128-132
    • Lecrubier, C1    Lecompte, T2    Potevin, F3
  • 47
    • 0030463618 scopus 로고    scopus 로고
    • A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry
    • Lee DH Warkentin TE Denomme GA A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry British Journal of Haematology 95 1996 724 731
    • (1996) British Journal of Haematology , vol.95 , pp. 724-731
    • Lee, DH1    Warkentin, TE2    Denomme, GA3
  • 48
    • 0027257980 scopus 로고
    • Mode of interaction between platelet factor 4 and heparin
    • Maccarana M Lindahl U Mode of interaction between platelet factor 4 and heparin Glycobiology 3 1993 271 277
    • (1993) Glycobiology , vol.3 , pp. 271-277
    • Maccarana, M1    Lindahl, U2
  • 49
    • 0027442550 scopus 로고
    • Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172)
    • Magnani HN Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172) Thrombosis and Haemostasis 70 1993 554 561
    • (1993) Thrombosis and Haemostasis , vol.70 , pp. 554-561
    • Magnani, HN1
  • 50
    • 0029093011 scopus 로고
    • Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions
    • Marcus AJ Safier LB Broekman MJ Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions Thrombosis and Haemostasis 74 1995 213 217
    • (1995) Thrombosis and Haemostasis , vol.74 , pp. 213-217
    • Marcus, AJ1    Safier, LB2    Broekman, MJ3
  • 51
    • 0024330929 scopus 로고
    • Human platelet factor 4 monomer-dimer-tetramer equilibria investigated by H NMR spectroscopy
    • Mayo KH Chen MJ Human platelet factor 4 monomer-dimer-tetramer equilibria investigated by H NMR spectroscopy Biochemistry 28 1989 9469 9478
    • (1989) Biochemistry , vol.28 , pp. 9469-9478
    • Mayo, KH1    Chen, MJ2
  • 52
    • 0029671459 scopus 로고    scopus 로고
    • TNF-α renders human neutrophils responsive to platelet factor 4
    • Petersen F Lidwig A Flad HD Brandt E TNF-α renders human neutrophils responsive to platelet factor 4 Journal of Immunology 156 1996 1954 1962
    • (1996) Journal of Immunology , vol.156 , pp. 1954-1962
    • Petersen, F1    Lidwig, A2    Flad, HD3    Brandt, E4
  • 53
    • 0030703541 scopus 로고    scopus 로고
    • Differences in specificity of heparin-dependent antibodies developed under low-molecular-weight-heparin therapy and higher cross-reactivity with Orgaran
    • Pouplard C Amiral J Borg JY Differences in specificity of heparin-dependent antibodies developed under low-molecular-weight-heparin therapy and higher cross-reactivity with Orgaran British Journal of Haematology 99 1997 273 280
    • (1997) British Journal of Haematology , vol.99 , pp. 273-280
    • Pouplard, C1    Amiral, J2    Borg, JY3
  • 54
    • 0029918409 scopus 로고    scopus 로고
    • Platelets of patients with peripheral arterial disease are hypersensitive to heparin
    • Reininger CB Greinacher A Graf J Platelets of patients with peripheral arterial disease are hypersensitive to heparin Thrombosis Research 81 1996 641 649
    • (1996) Thrombosis Research , vol.81 , pp. 641-649
    • Reininger, CB1    Greinacher, A2    Graf, J3
  • 55
    • 0015598386 scopus 로고
    • Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations
    • Rhodes GR Dixon RH Sylver D Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations Surgery Gynecology Obstetrica 136 1973 409 416
    • (1973) Surgery Gynecology Obstetrica , vol.136 , pp. 409-416
    • Rhodes, GR1    Dixon, RH2    Sylver, D3
  • 56
    • 0023113558 scopus 로고
    • Selective binding of heparins to human endothelial cells. Implications for pharmacokinetics
    • van Rijn JLML Trillou M Mardiguian J Selective binding of heparins to human endothelial cells. Implications for pharmacokinetics Thrombosis Research 45 1987 211 222
    • (1987) Thrombosis Research , vol.45 , pp. 211-222
    • van Rijn, JLML1    Trillou, M2    Mardiguian, J3
  • 57
    • 0024518722 scopus 로고
    • Interaction of platelet factor four with cultured vascular endothelial cells
    • Rybak ME Gimbrone MA Davies PF Handin RI Interaction of platelet factor four with cultured vascular endothelial cells Blood 73 1989 1534 1539
    • (1989) Blood , vol.73 , pp. 1534-1539
    • Rybak, ME1    Gimbrone, MA2    Davies, PF3    Handin, RI4
  • 58
    • 0022640930 scopus 로고
    • A diagnostic test for heparin-induced thrombocytopenia
    • Sheridan D Carter C Kelton JG A diagnostic test for heparin-induced thrombocytopenia Blood 67 1986 27 30
    • (1986) Blood , vol.67 , pp. 27-30
    • Sheridan, D1    Carter, C2    Kelton, JG3
  • 59
    • 0023706045 scopus 로고
    • Characterization of platelet binding of heparins and other glycosaminoglycans
    • Sobel M Adelman B Characterization of platelet binding of heparins and other glycosaminoglycans Thrombosis Research 50 1988 815 826
    • (1988) Thrombosis Research , vol.50 , pp. 815-826
    • Sobel, M1    Adelman, B2
  • 60
    • 0029027906 scopus 로고
    • Heparin-induced thrombocytopenia: an improved method of detection based on lumi-aggregometry
    • Stewart MW Etches WS Boshkov LK Gordon PA Heparin-induced thrombocytopenia: an improved method of detection based on lumi-aggregometry British Journal of Haematology 91 1995 173 177
    • (1995) British Journal of Haematology , vol.91 , pp. 173-177
    • Stewart, MW1    Etches, WS2    Boshkov, LK3    Gordon, PA4
  • 61
    • 0026661146 scopus 로고
    • A model of the platelet factor 4 complex with heparin
    • Stuckey JA St Charles R Edwards B A model of the platelet factor 4 complex with heparin Proteins 14 1992 277 287
    • (1992) Proteins , vol.14 , pp. 277-287
    • Stuckey, JA1    St Charles, R2    Edwards, B3
  • 62
    • 0030887879 scopus 로고    scopus 로고
    • Characterization of the humoral immune response in heparin-induced thrombocytopenia
    • Suh J-S Malik M-I Aster R-H Visentin G-P Characterization of the humoral immune response in heparin-induced thrombocytopenia American Journal of Hematology 54 1997 196 201
    • (1997) American Journal of Hematology , vol.54 , pp. 196-201
    • Suh, J-S1    Malik, M-I2    Aster, R-H3    Visentin, G-P4
  • 63
    • 0027408343 scopus 로고
    • Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes
    • Tanaka Y Adams DH Shaw S Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes Immunology Today 14 1993 111 115
    • (1993) Immunology Today , vol.14 , pp. 111-115
    • Tanaka, Y1    Adams, DH2    Shaw, S3
  • 64
    • 0029809594 scopus 로고    scopus 로고
    • A bioluminescent adenosine nucléotide release assay for the diagnosis of heparin-induced thrombocytopenia
    • Teitel JM Gross P Blake P Garvey MB A bioluminescent adenosine nucléotide release assay for the diagnosis of heparin-induced thrombocytopenia Thrombosis and Haemostasis 73 1996 479
    • (1996) Thrombosis and Haemostasis , vol.73 , pp. 479
    • Teitel, JM1    Gross, P2    Blake, P3    Garvey, MB4
  • 65
    • 0030964597 scopus 로고    scopus 로고
    • A sensitive and specific functional flow cytometric assay for the diagnosis of heparin induced thrombocytopenia
    • Tomer A A sensitive and specific functional flow cytometric assay for the diagnosis of heparin induced thrombocytopenia British Journal of Haematology 98 1997 648 656
    • (1997) British Journal of Haematology , vol.98 , pp. 648-656
    • Tomer, A1
  • 67
  • 68
    • 0028009642 scopus 로고
    • Antibodies from patients with heparin induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
    • Visentin GP Ford SE Scott JP Aster RH Antibodies from patients with heparin induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells Journal of Clinical Investigation 93 1994 81 88
    • (1994) Journal of Clinical Investigation , vol.93 , pp. 81-88
    • Visentin, GP1    Ford, SE2    Scott, JP3    Aster, RH4
  • 69
    • 0030258647 scopus 로고    scopus 로고
    • Patients with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin: platelet factor 4 complexes
    • Visentin GP Malik M Cyganiak KA Aster RH Patients with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin: platelet factor 4 complexes Journal of Laboratory and Clinical Medicine 128 1996 376 383
    • (1996) Journal of Laboratory and Clinical Medicine , vol.128 , pp. 376-383
    • Visentin, GP1    Malik, M2    Cyganiak, KA3    Aster, RH4
  • 70
    • 0017762878 scopus 로고
    • Primary structure of human platelet factor 4
    • Walz DA Wu VY de Lamo R Primary structure of human platelet factor 4 Thrombosis Research 11 1977 893 898
    • (1977) Thrombosis Research , vol.11 , pp. 893-898
    • Walz, DA1    Wu, VY2    de Lamo, R3
  • 71
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocytopenia
    • Warkentin TE Kelton JG A 14-year study of heparin-induced thrombocytopenia American Journal of Medicine 101 1996 502 507
    • (1996) American Journal of Medicine , vol.101 , pp. 502-507
    • Warkentin, TE1    Kelton, JG2
  • 72
    • 0029035681 scopus 로고
    • Heparin induced thrombocytopenia in patients treated with low molecular weight heparin or unfractionated heparin
    • Warkentin TE Levine MN Hirsh J Heparin induced thrombocytopenia in patients treated with low molecular weight heparin or unfractionated heparin New England Journal of Medicine 332 1995 1330 1335
    • (1995) New England Journal of Medicine , vol.332 , pp. 1330-1335
    • Warkentin, TE1    Levine, MN2    Hirsh, J3
  • 73
    • 0001375302 scopus 로고
    • Warfarin treatment of deep vein thrombosis complicating heparin-induced thrombocytopenia (HIT) is a risk factor for initiation of venous limb gangrene: report of nine patients implicating the interacting procoagulant effects of two anticoagulant agents
    • (abstract) Warkentin TE Russet JI Johnston M Kelton JG Warfarin treatment of deep vein thrombosis complicating heparin-induced thrombocytopenia (HIT) is a risk factor for initiation of venous limb gangrene: report of nine patients implicating the interacting procoagulant effects of two anticoagulant agents Thrombosis and Haemostasis 73 1995 804
    • (1995) Thrombosis and Haemostasis , vol.73 , pp. 804
    • Warkentin, TE1    Russet, JI2    Johnston, M3    Kelton, JG4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.