Use of liquid chromatography-tandem mass spectrometry for the quantitative and qualitative analysis of an antipsychotic agent and its metabolites in human plasma and urine

Journal of Chromatography A

Volumn 794, Issue 1-2, 1998, Pages 27-36

  Dear, Gordon J ^a   Fraser, Ian J ^a   Patel, Dipak K ^b   Long, Jeffrey ^a   Pleasance, Stephen ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

Author keywords

2 amino N (4 (4 (1,2 benzisothiazol 3 yl) 1 piperazinyl)butyl) benzamide; Antipsychotic agent; Tandem mass spectrometry

Indexed keywords

2 AMINO [4 [4 (1,2 BENZISOTHIAZOL 3 YL) 1 PIPERAZINYL]BUTYL]BENZAMIDE; NEUROLEPTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG METABOLISM; DRUG URINE LEVEL; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANTIPSYCHOTIC AGENTS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DOUBLE-BLIND METHOD; HUMANS; MASS SPECTROMETRY; SPECTROMETRY, FLUORESCENCE;

EID: 0032559168     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(97)00688-2     Document Type: Article

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