Probiotics reinforce mucosal degradation of antigens in rats: Implications for therapeutic use of probiotics

Journal of Nutrition

Volumn 128, Issue 12, 1998, Pages 2313-2318

  Pessi, Tanja ^a   Sütas, Yelda ^a   Marttinen, Aulis ^b   Isolauri, Erika ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Dietary antigen; Mucosal degradation; Probiotics; Rats

Indexed keywords

BETA LACTOGLOBULIN; HORSERADISH PEROXIDASE; IMMUNOGLOBULIN A; PROBIOTIC AGENT; PROTEIN HYDROLYSATE; SECRETORY IMMUNOGLOBULIN;

ANIMAL EXPERIMENT; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; INTESTINE ABSORPTION; INTESTINE EPITHELIUM; INTESTINE FLORA; INTESTINE FUNCTION; INTESTINE MUCOSA; JEJUNUM MUCOSA; LACTOBACILLUS; MALE; MILK; NONHUMAN; RAT;

ANIMALIA; ARMORACIA RUSTICANA; LACTOBACILLUS;

EID: 0032411153     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/128.12.2313     Document Type: Article

References (39)

1. Armstrong, W. M. (1987) Cellular mechanisms of ion transport in the small intestine. In: Physiology of the gastrointestinal tract (Johnson, L. R., ed.), pp. 1251-1265. Raven Press, New York.
2. Bengtmark, S. & Jeppsson, B. (1995) Gastrointestinal surface protection and mucosa reconditioning. J. Parent. Enteral. Nutr. 19: 410-415.
3. Brandzaeg, P. (1995) Molecular and cellular aspects of the secretory immunoglobulin system. APMIS 103: 1-19.
4. DeSimone, C., Bianchi-Salvadori, B., Negri, R., Ferrazi, M., Baldinelli, L. & Vesely, R. (1986) The adjuvant effect of yogurt on production of gamma-interferon by ConA-stimulated human peripheral blood lymphocytes. Nutr. Rep. Int. 33: 419-433.
5. Drasar, B. S. & Shiner, M. (1969) Studies on the intestinal flora. II. Bacterial flora of the small intestine in patients with gastrointestinal disorders. Gut 10: 812-819.
6. Guihot, G., Merle, V., Lebotgne, M., Pivert, G., Corriol, O., Brousse, N., Ricour, C.& Colomb, V. (1997) Enteral nutrition modifies gut-associated lymphoid tissue in rat regardless of the molecular form of nitrogen supply. J. Pediatr. Gastroenterol. Nutr. 24: 153-161.
7. Helgeland, L., Vaage, J. T., Rolstad, B., Midvedt, T. & Brandtzaeg, P. (1996) Microbial colonization influences composition and T-cell receptor V beta repertoire of intraepithelial lymphocytes in rat intestine. Immunology 89: 494-501.
8. Heyman, M., Ducroc, R., Desjeux, J. F. & Morgat, J. L. (1982) Horseradish peroxidase transport across adult rabbit jejunum in vitro. Am. J. Physiol. 242: G558-G564.
9. Heyman, M., Crain-Denoyelle, M., Corthier, G. & Desjeux, J. F. (1986) Postnatal development of protein absorption in conventional and germ-free mice. Am. J. Physiol. 251: G326-G331.
10. Heyman, M., Gorthier, G., Petit, A., Meslin, J. C., Moreau, C. & Desjeux, J. F. (1987) Intestinal absorption of macromolecules during viral enteritis: an experimental study on rotavirus-infected conventional and germ-free mice. Pediatr. Res. 22: 72-78.
11. Husby, S., Metecky, J., Moldoveanu, Z.. Holland, S. & Elson, C. O. (1994) Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding. J. Immunol. 152: 4663-4670.
12. Isolauri, E., Gotteland, G., Heyman, M., Porchart, P. & Desjeux, J. F. (1990) Antigen absorption in rabbit bacterial diarrhea (RDEC-1). In vitro modifications ileum and Peyer's patches. Dig. Dis. Sci. 35: 360-366.
13. Isolauri, E., Majamaa, H., Arvola, T., Rantala, I. & Arvilommi, H. (1993) Lactobacillus strain GG reverses increased intestinal permeability induced by cow milk in suckling rats. Gastroenterology 105: 1643-1650.
14. Kaila, M., Isolauri, E., Soppi, E., Virtanen, E., Laine, S. & Arvilommi, H. (1992) Enhancement of the circulating antibody secreting cell response in human diarrhoea by a human Lactobacillus strain. Pediatr. Res. 32: 141-144.
15. Lycke, N. & Holmgren, J. (1986) Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology 59: 301-308.
16. Macpherson, A., Khoo, U. Y., Forgacs, I., Philpott-Howard, J. & Bjarnason, I. (1996) Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria. Gut 38: 365-375.
17. Mäkinen-Kiljunen, S. & Palosuo, T. (1992) A sensitivity enzyme-linked immunosorbent assay for determination of bovine β-lactoglobulin in infant feeding formulas and in human milk. Allergy 47: 347-352.
18. Malin, M., Suomalainen, H., Saxelin, M. & Isolauri, E. (1996a) Promotion of IgA immune responses in patients with Crohn's disease by oral bacteriotherapy with Lactobacillus GG. Ann. Nutr. Metab. 40: 137-145.
19. Malin, M., Verronen, P., Mykkänen, H., Salminen, S. & Isolauri, E. (1996b) Increased bacterial urease activity in faeces in juvenile chronic arthritis: evidence of altered intestinal microflora? Br. J. Rheumat. 35: 689-694.
20. Marano, C. W., Laughlin, K. V., Russo, L. M., Peralta-Soler, A. & Mullin, J. M. (1993) Long term effects of tumor necrosis factor on LCC-PK1 transepithelial resistance. J. Cell Physiol. 157: 519-527.
21. Marcon-Genty, D., Krempf, M. & Tome, D. (1991) Transmucosal transport of phytohemagglutinin, concanavalin A and alpha-lactalbumin across rabbit ileum in vitro. Gastroenterol. Clin. Biol. 15: 10-15.
22. Markwell, M. A. (1982) A new solid state reagent to iodinate proteins. I. Conditions for efficient labelling of antiserum. Anal. Biochem. 125: 427-432.
23. Moreau, M. C., Ducluzeau, R., Guy-Grand, D. & Muller, M. C. (1987) Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin. Infect. Immun. 21: 532-539.
24. Peng, H. J., Turner, M. W. & Strobel, S. (1990) The generation of a tolerogen after ingestion of ovalbumin is time dependent and unrelated to serum levels of immunoreactive antigen. Clin. Exp. Immunol. 81: 520-525.
25. Perdigón, G., de Macías, M. E. N., Alvarez, S., Oliver, G. & de Ruiz Holgadol, A. P. (1988) Systemic augmentation of immune response in mice by feeding fermented milks with Lactobacillus casei and Lactobacillus acidophilus. Immunology 63: 17-23.
26. Perdigon, G., Alvarez, S. & de Ruiz Holgado, A. P. (1991) Immunoadjuvant activity of oral Lactobacillus casei: influence of dose on the secretory immune response and protective capacity in intestinal infections. J. Dairy Res. 58: 485-496.
27. Rugtveit, J., Nislen, E. M., Bakka, A., Carlsen, H., Brantzaeg, P. & Scott, H. (1997) Cytokine profiles differ in newly recruited and resident subset of mucosal macrophages from inflammatory bowel disease. Gastroenterology 112: 1493-1505.
28. Salminen, S., Bouley, C., Boutron-Ruault, M. C., Cummings, J., Franck, A., Gibson, G., Isolauri, E., Moreau, M. C., Roberfroid, M. & Rowland, I. R. (1998) Functional food science and gastrointestinal physiology and function. Br. J. Nutr. 80: 5147-5171.
29. Sharma, R. & Schumacher, U. (1995) Morphometric analysis of intestinal mucins under different dietary conditions and gut flora in rats. Dig. Dis. Sci. 40: 2532-2539.
30. Slomiany, B. L., Sarosiek, Y. & Slomiany, A. (1987) Gastric mucus and the mucosal barrier. Dig. Dis. Sci. 5: 125-145.
31. Stokes, C. R., Soothill, J. F. & Turner, M. W. (1975) Immune exclusion is a function of IgA. Nature 255: 745-746.
32. Strobel, W. & Ehrhardt, R. O. (1993) Chronic intestinal inflammation: an unexpected outcome in cytokine or T cell receptor mutant mice. Cell 75: 203-205.
33. Sudo, N., Sawamura, S. A., Tanaka, K., Aiba, Y., Kubo, C. & Koga, Y. (1997) The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol. 157: 1739-1745.
34. Sütas, Y., Soppi, E., Korhonen, H., Syväoja, E. L., Saxelin, M., Rokka, T. and Isolauri, E. (1996) Suppression of lymphocyte proliferation in vitro by bovine caseins hydrolysed with Lactobacillus GG-derived enzymes. J. Allergy Clin. Immunol. 98: 216-224.
35. Sütas, Y., Hurme, M. & Isolauri, E. (1997) Down-regulation of antiCD3 antibody-induced IL-4 production by bovine caseins hydrolysed with Lactobacillus GG-derived enzymes. Scand. J. Immunol. 43: 687-689.
36. Teichberg, S., Isolauri, E., Wapnir, R. A., Roberts, B. & Lifshitz, F. (1990) Development of neonatal rat small intestinal barrier to non-specific macromolecular absorption: effect of early weaning to artificial diets. Pediatr. Res. 28: 31-37.
37. Thompson, P. J. & Stewart, G. A. (1993) Allergens. In: Allergy (Holgate, S. T. & Church, M. K., eds.), pp. 1.1-1.14. Gower Medical Publishing, London, UK.
38. Weiner, H. L, Friedman, A., Miller, A., Khoury, S. J., Al-Sabbagh, A., Santos, L., Sayegh, M., Nussenblatt, R. B., Trentham, D. E. & Hafler, D. A. (1994) Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral adminstration of autoantigens. Annu. Rev. Immunol. 12: 809-837.
39. Wyatt, J., Vogelsang, H., Hübl, W., Waldhöer, T. & Lochs, H. (1993) Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet 341: 1437-1439.