Increased levels of enkephalin following natural sunlight (combined with salt water bathing at the Dead Sea) and ultraviolet A irradiation

British Journal of Dermatology

Volumn 139, Issue 6, 1998, Pages 1012-1019

  Nissen, J B ^a   Avrach, W W ^b   Hansen, E S ^a   Stengaard Pedersen, K ^a   Kragballe, K ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b Panopticon Dermatological Center   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD68 ANTIGEN; ENKEPHALIN; METENKEPHALIN; OPIATE PEPTIDE; SEA WATER;

ADULT; ARTICLE; BATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOMODULATION; INFLAMMATION; KERATINOCYTE; PRIORITY JOURNAL; PSORIASIS; RADIATION DOSE; SEA; SUNLIGHT; ULTRAVIOLET A RADIATION;

ADULT; BIOPSY, NEEDLE; COMBINED MODALITY THERAPY; ENKEPHALINS; HELIOTHERAPY; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PHYSICAL THERAPY MODALITIES; PSORIASIS; THALASSOTHERAPY; TREATMENT OUTCOME; ULTRAVIOLET THERAPY;

EID: 0032406686     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02557.x     Document Type: Article

References (31)

1. Zagon IS, Wu Y, McLaughlin PJ. The opioid growth factor, [Met5]-enkephalin, and the (zeta) opioid receptor are present in human and mouse skin and tonically act to inhibit DNA synthesis in the epidermis. J Invest Dermatol 1996; 106: 490-7.
2. Nissen JB, Lund M, Stengaard-Pedersen K, Kragballe K. Enkephalin-like immunoreactivity in human skin is found selectively in a fraction of CD68 positive dermal cells: increase of enkephalin-positive cells in lesional psoriasis. Arch Dermatol Res 1997; 289: 265-71.
3. Przewlocki R, Hassan AHS, Lason W et al. Gene expression and localization of opioid peptides in immune cells of inflamed tissue. Functional role in antinociception. Neuroscience 1992; 48: 491-500.
4. Stein C, Hassan AHS, Przewlocki R et al. Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation. Proc Natl Acad Sci USA 1990; 87: 59 35-9.
5. Hucklebridge FH, Hudspith BN, Lydyard PM, Brostoff J. Stimulation of human peripheral lymphocytes by methionine enkephalin and delta(δ)-selective opioid analogues. Immunopharmacology 1990; 19: 87-91.
6. Perez-Castrillon J-L, Perez-Arelano J-L, Garcia-Palomo J-D et al. Opioids depress in vitro human monocyte chemotaxis. Immunopharmacology 1992; 23: 57-61.
7. Brown SL, Van Epps DE. Opioid peptides modulate production of interferon-γ by human mononuclear cells. Cell Immunol 1986; 103: 19-26.
8. Zhong F, Li X-Y, Yang S-L. Methionine-enkephalin augments interleukin-6 production and gene expression. Acta Pharmacol Sinica 1995; 16: 205-9.
9. Apte RN, Durum SK, Oppenheim JJ. Opioids modulate interleukin-1 production and secretion by bone-marrow macrophages. Immunol Lett 1990; 24: 141-8.
10. Nissen JB, Kragballe K. Enkephalins modulate differentiation of normal human keratinocytes in vitro. Exp Dermatol 1997; 6: 222-9.
11. Vermeer M, Schmieder GJ, Yoshikawa T et al. Effects of ultraviolet B light on cutaneous immune responses of humans with deeply pigmented skin. J Invest Dermatol 1991; 97: 729-34.
12. Soter NA. Acute effects of ultraviolet radiation on the skin. Semin Dermatol 1990; 9: 11-15.
13. Streilein JW, Taylor JR, Vincek V et al. Immune surveillance and sunlight-induced skin cancer. Immunol Today 1994; 15: 174-9.
14. Toda K, Miyachi Y, Nesumi N et al. UVB/PUVA-induced suppression of human natural killer activity is reduced by superoxide dismutase and/or interleukin 2 in vitro. J Invest Dermatol 1986; 86: 519-22.
15. Køck A, Schwarz T, Kirnbauer R et al. Human keratinocytes are a source for tumor necrosis factor α: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 1990; 172: 1609-14.
16. Urbanski A, Schwarz T, Neuner P et al. Ultraviolet light induces increased circulating interleukin-6 in humans. J Invest Dermatol 1990; 94: 808-11.
17. Granstein RD, Sauder DN. Whole-body exposure to ultraviolet radiation results in increased serum interleukin-1 activity in humans. Lymphokine Res 1987; 6: 187-93.
18. Goldberg LH, Kushelevsky A. Ultraviolet light measurements at the Dead Sea. In: Psoriasis, Proceedings of the Second International Symposium, 1976 (Farber E, ed.), New York: Yorke Medical Books, 1977; 461-3.
19. Abels DJ, Rose T, Bearman JE. Treatment of psoriasis at a Dead Sea dermatology clinic. Int J Dermatol 1995; 34: 134-7.
20. Council on Scientific Affairs. Harmful effects of ultraviolet irradiation. JAMA 1989; 262: 380-4.
21. Bhathena SJ, Smith PM, Kennedy BW et al. Simultaneous extraction of β-endorphin and leu-and met-enkephalin from human and rat plasma. Life Sci 1989; 45: 901-6.
22. Lavker RM, Gerberick F, Veres D et al. Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin. J Am Acad Dermatol 1995; 32: 53-62.
23. Czlonkowski A, Stein C, Herz A. Peripheral mechanisms of opioid antiception in inflammation: involvement of cytokines. Eur J Pharmacol 1993; 242: 229-35.
24. Kavelaars A, Berkenbosch F, Croiset G et al. Induction of β-endorphin secretion by lymphocytes after subcutaneous administration of corticotropin-releasing factor. Endocrinology 1990; 126: 759-64.
25. Lemaire S, Day R, Dumont M, Chouinard L. Dynorphin and enkephalins in adrenal paraneurones. Opiates in the adrenal medulla. Can J Physiol Pharmacol 1984; 62: 484-92.
26. Wintzen M, Yaar M, Burbach JPH, Gilchrest BA. Proopiomelanocortin gene product regulation in keratinocytes. J Invest Dermatol 1996; 106: 673-8.
27. Wintzen M, Gilchrest BA. Proopiomelanocortin, its derived peptides, and the skin. J Invest Dermatol 1996; 106: 3-10.
28. Mawn VB, Fleischer AB. A survey of attitudes, beliefs, and behavior regarding tanning bed use, sunbathing, and sunscreen use. J Am Acad Dermatol 1993; 29: 959-62.
29. Fleischer AB, Clark AR, Rapp SR et al. Commercial tanning bed treatment is an effective psoriasis treatment: results from an uncontrolled clinical trial. J Invest Dermatol 1997; 109: 170-4.
30. Singer EA, Mitra SP, Carraway RE. Plasma protein(s) yields metenkephalin-related peptides in near-micromolar concentrations when treated with pepsin. Endocrinology 1986; 119: 1527-33.
31. Mozzanica N, Finzi AF, Foppa S et al. Association between circadian rhythms of endogenous hypothalamic opioid peptides and of natural killer cell activity. Int J Immunopharmacol 1991; 13: 317-21.