Enkephalins modulate differentiation of normal human keratinocytes in vitro

Experimental Dermatology

Volumn 6, Issue 5, 1997, Pages 222-229

  Nissen, Judith B ^a   Kragballe, Kund ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Differentiation; Endorphin; Enkephalin; Keratinocyte; Proliferation

Indexed keywords

ENDORPHIN; ENKEPHALIN;

AMINO ACID ANALYSIS; ANTINOCICEPTION; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL PROLIFERATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; KERATINOCYTE; PSORIASIS;

BETA-ENDORPHIN; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, LEUCINE; ENKEPHALIN, LEUCINE-2-ALANINE; ENKEPHALIN, METHIONINE; HUMANS; KERATINOCYTES; KERATINS; MELPHALAN; NALTREXONE; NARCOTIC ANTAGONISTS; SKIN; TRANSGLUTAMINASES;

EID: 0030764165     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1997.tb00166.x     Document Type: Article

References (13)

1. Przewlocki R, Hassan A H S, Lason W, Epplen C, Herz A, Stein C. Gene expression and localization of opioid pep tides in immune cells of inflamed tissue. Functional role in antinociception. Neurosci 1992: 48: 491-500.
2. Stein C, Hassan A H S, Przewlocki R, Gramsch C, Peter K, Herz A. Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation. Proc Natl Acad Sci 1990: 87: 5935-5939.
3. Stein C, Hassan A H S, Lehrberger K, Giefing J, Yassouridis A. Local analgesic effect of endogenous opioid peptides. Lancet 1993: 342: 321-324.
4. Heijnen C J, Kavelaars A, Ballieux R E. B-endorphine: cytokine and neuropeptide. Immunol Rev 1991: 119: 41-63.
5. Sibinga NES, Goldstein A. Opioid peptides and opioid receptors in cells of the immune system. Ann Rev Immunol 1988: 6: 219-249.
6. Schafer M, Carter C, Stein C. Interleukin 1B and cortitropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc Natl Acad Sci 1994: 91: 4219-4223.
7. Kuis W, Villiger P M, Leser H, Lotz M. Differential processing of proenkephalin-A by human peripheral blood monocytes and T lymphocytes. J Clin Invest 1991: 88: 817-824.
8. Slominski A, Wortsman J, Mazurkiewicz J E et al. Detection of proopimelanocortin-derived antigens in normal and pathologic human skin. J Lab Clin Med 1993: 122: 658-666.
9. Slominski A, Paus R, Wortsman J. On the potential role of opioimelanocortin in skin physiology and pathology. Mol Cell Endocrinol 1993: 93: C1-C6.
10. Bhargava H N. Opioid systems and immune functions. In: Plotnikoff N., ed. Stress and immunity. Boca Raton, Florida: CRC Press, 1991: 329-341.
11. + T cells. Cell Immunol 1996: 154: 109-122.
12. Hedner T, Cassuto J. Opioids and opioid receptors in peripheral tissues. Scand J Gastroent 1987: 22: 27-46.
13. Zagon I S, Wu Y, McLaughlin P J. The opioid growth factor, [Met5]-enkephalin, and the ζ opioid receptor are present in human and mouse skin and tonically act to inhibit DNA synthesis in the epidermis. J Invest Dermatol 1996: 106: 490-497.