Selective coupling of STAT factors to the mouse prolactin receptor

European Journal of Biochemistry

Volumn 258, Issue 2, 1998, Pages 784-793

  Mayr, Stefan ^a   Welte, Thomas ^a   Windegger, Michaela ^a   Lechner, Judith ^a   May, Petra ^b   Heinrich, Peter C ^b   Horn, Friedemann ^b   Doppler, Wolfgang ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Mammary gland; Phosphotyrosine; Prolactin; SH 2 domain; STAT factors

Indexed keywords

ERYTHROPOIETIN; GLYCOPROTEIN GP 130; PHOSPHOTYROSINE; PROLACTIN; PROLACTIN RECEPTOR; STAT1 PROTEIN; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CARBOXY TERMINAL SEQUENCE; DNA BINDING; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; DNA-BINDING PROTEINS; GENES, REPORTER; MAMMARY GLANDS, ANIMAL; MICE; MILK PROTEINS; MUTATION; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROMOTER REGIONS (GENETICS); RECEPTORS, PROLACTIN; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA;

EID: 0032403895     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2580784.x     Document Type: Article

References (45)

1. Pellegrini, S. & Dusanter-Fourt, I. (1997) The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs), Eur: J. Biochem. 248, 615-633.
2. Fujitani, Y., Hibi. M., Fukuda, T., Takahashi-Tezuka, M., Yoshida, H., Yamaguchi, T., Sugiyama, K., Yamanaka, Y., Nakajima, K. & Hirano, T. (1997) An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT, Oncogene 14, 751-761.
3. Cao, X. M., Tay, A., Guy, G. R. & Tan, Y. H. (1996) Activation and association of stat3 with Src in v-Src- transformed cell lines, Mol. Cell. Biol. 16, 1595-1603.
4. Greenlund, A. C., Farrar, M. A., Viviano, B. L. & Schreiber, R. D. (1994) Ligand-induced IFNγ receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91), EMBO J. 13, 1591-1600.
5. Gerhartz, C., Heesel, B., Sasse, J., Hemmann, U., Landgraf, C., Schneider-Mergener, J., Horn, F., Heinrich, P. C. & Graeve, L. (1996) Differential activation of acute phase response factor/ STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. 1. Definition of a novel phosphotyrosine motif mediating STAT1 activation, J. Biol. Chem. 271, 12991- 12998.
6. Hemmann, U., Gerhartz, C., Heesel, B., Sasse, J., Kurapkat, G., Grotzinger, J., Wollmer, A., Zhong, Z., Darnell, J. E., Graeve, L., Heinrich, P. C. & Horn, F. (1996) Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. 2. Src homology SH2 domains define the specificity of STAT factor activation, J. Biol. Chem. 271, 12999-13007.
7. Smit, L. S., Meyer, D. J., Billestrup, N., Norstedt, G., Schwartz, J. & CarterSu, C. (1996) The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH, Mol. Endocrinol. 10, 514-533.
8. Klingmüller, U., Bergelson, S., Hsiao, J. G. & Lodish, H. F. (1996) Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5, Proc. Natl Acad. Sci. USA 93, 8324-8328.
9. Quelle, F. W., Wang, D., Nosaka, T., Thierfelder, W. E., Stravopodis, D., Weinstein, Y. & Ihle, J. N. (1996) Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response, Mol. Cell. Biol. 16, 1022-1631.
10. vanDijk, T. B., Caldenhoven, K., Raaijmakers, J. A. M., Lammers, J. W. J., Koenderman, L. & deGroot, R. P. (1997) Multiple tyrosine residues in the intracellular domain of the common beta subunit of the interleukin 5 receptor are involved in activation of STAT5, FEBS Lett. 412, 161-164.
11. May, P., Gerhartz, C., Heesel, B., Welte, T., Doppler, W., Graeve, L., Horn, F. & Heinrich, P. C. (1996) Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation. FEBS Lett. 394, 221-220.
12. Hou, J. Z., Schindler, U., Henzel, W. J., Ho, T. C., Brasseur, M. & McKnight, S. L. (1994) An interleukin-4-induced transcription factor: IL-4 Stat. Science 265, 1701-1706.
13. Schindler, U., Wu, P., Rothe, M., Brasseur, M. & McKnight, S. L. (1995) Components of a Stat recognition code: evidence for two layers of molecular selectivity, Immunity 2, 689-697.
14. Ellis, L., Clauser, K., Morgan, D. O., Edery, M., Roth, R. A. & Rutter, W. J. (1986) Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose, Cell 45, 721-732.
15. Deng, W. P. & Nickoloff, J. A. (1992) Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal. Biochem. 200, 81-88.
16. Lechner, J., Welte, T., Tomasi, J. K., Bruno, P., Cairns, C., Gustafsson, J.-Å. & Doppler, W. (1997) Promoter-dependent synergy between glucocorticoid receptor and Stat5 in the activation of β-casein gene transcription, J. Biol. Chem. 272, 20954-20960.
17. Doppler, W., Höck, W., Hofer, P., Groner, B. & Ball, R. K. (1990) Prolactin and glucocorticoid hormones control transcription of the β-casein gene by kinetically distinct mechanisms, Mol. Endocrinol. 4, 912-919.
18. Weite, T., Garimorth, K., Philipp, S., Jennewein, P., Huck, C., Cato, A. C. B. & Doppler, W. (1994) Involvement of Ets-related proteins in hormone-independent mammary cell-specific gene expression. Eur. J. Biochem. 223, 997-1006.
19. Matthews, J. C., Hori, K. & Cormier, M. J. (1977) Purification and properties of Renilla reniformis luciferase, Biochemistry 16, 85-91.
20. Wartmann, M., Cella, N., Hofer, P., Groner, B., Liu, X. W., Hennighausen, L. & Hynes, N. E. (1996) Lactogenic hormone activation of Stat5 and transcription of the beta-casein gene in mammary epithelial cells is independent of p42 ERK2 mitogen-activated protein kinase activity, J. Biol. Chem. 271, 31863-31868.
21. DaSilva, L., Rui, H., Erwin, R. A., Howard, O. M. Z., Kirken, R. A., Malabarba, M. G., Hackett, R. H., Larner, A. C. & Farrar, W. L. (1996) Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580, Mol. Cell. Endocrinol. 117, 131-140.
22. Kirken, R. A., Malaharba, M. G., Xu, J., Liu, X. W., Farrar, W. L., Hennighausen, L., Larner, A. C., Grimley, P. M. & Rui, H. (1997) Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes. J. Biol. Chem. 272, 14098-14103.
23. Gouilleux, F., Moritz, D., Humar, M., Moriggl, R., Berchtold, S. & Groner, B. (1995) Prolactin and interleukin-2 receptors in T lymphocytes signal through a MGF-STAT5-like transcription factor, Endocrinology 136, 5700-5708.
24. David, M., Petricoin, E. F., Igarashi, K., Feldman, G. M. Finbloom, D. S. & Larner, A. C. (1994) Prolactin activates the interieron-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation, Proc. Natl Acad. Sci. USA 91, 7174-7178.
25. Wang, Y. F., Oneal, K. D. & Yu-Lee, L. Y. (1997) Multiple prolactin (PRL) receptor cytoplasmic residues and statl mediate PRL signaling to the interferon regulatory factor-1 promoter, Mol. Endocrinol. 11, 1353-1364.
26. Welte, T., Garimorth, K., Philipp, S. & Doppler, W. (1994) Prolactin-dependent activation of a tyrosine phosphorylated DNA binding factor in mouse mammary epithelial cells. Mol. Endocrinol. 8, 1091-1102.
27. Moriggl, R., Berchtold, S., Friedrich, K., Standke, G. J. R., Kammer, W., Heim, M., Wissler, M., Stöcklin, E., Gouilleux, F. & Groner, B. (1997) Comparison of the transactivation domains of Stat5 and Stat6 in lymphoid cells and mammary epithelial cells, Mol. Cell. Biol. 17, 3663-3678.
28. Buck, K., Vanek, M., Groner, B. & Ball, R. K. (1992) Multiple forms of prolactin receptor messenger ribonucleic acid are specifically expressed and regulated in murine tissues and the mammary cell line HC11, Endocrinology 130, 1108-1114.
29. DaSilva, L., Howard, O. M. Z., Rui, H., Kirken, R. A. & Farrar, W. L. (1994) Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors, J. Biol. Chem. 269, 18267-18270.
30. Goupille. O., Daniel, N., Bignon, C., Jolivet, G. & Djiane, J. (1997) Prolactin signal transduction to milk protein genes: carboxy-terminal part of the prolactin receptor and its tyrosine phosphorylation are not obligatory for JAK2 and STAT5 activation, Mol. Cell. Endocrinol. 127, 155-169.
31. Scott, P., Kessler, M. A. & Schuler, L. A. (1992) Molecular cloning of the bovine prolactin receptor and distribution of prolactin and growth hormone receptor transcripts in fetal and utero-placental tissues, Mol. Cell. Endocrinol. 89, 47-58.
32. Jabbour, H. N., Clarke, L. A., Boddy, S., Pezet, A., Edery, M. & Kelly, P. A. (1996) Cloning, sequencing and functional analysis of a truncated cDNA encoding red deer prolactin receptor: an alternative tyrosine residue mediates beta-casein promoter activation, Mol. Cell. Endocrinol. 123, 17-26.
33. Sandra, O., Sohm, F., Deluze, A., Prunet, P., Edery, M. & Kelly, P. A. (1995) Expression cloning of a cDNA encoding a fish prolactin receptor. Proc. Natl Acad. Sci. USA 92, 6037-6041.
34. Ali, S., Pellegrini, I. & Kelly, P. A. (1991) A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor. J. Biol. Chem. 266, 20110-20117.
35. Gaffen, S. L., Lai, S. Y., Xu, W. D., Gouilleux, F., Groner, B., Goldsmith, M. A. & Greene, W. C. (1995) Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc. Natl Acad. Sci. USA 92, 7192-7196.
36. Lebrun, J.-J., Ali, S., Goffin, V., Ullrich, A. & Kelly, P. A. (1995) A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription, Proc. Natl Acad. Sci. USA 92, 4031-4035.
37. Moriggl, R., Gouilleux-Gruart, V., Jähne, R., Berchtold, S., Gartmann, C., Liu, X., Hennighausen, L., Sotiropoulos, A., Groner, B. & Gouilleux, F. (1996) Deletion of the carboxy-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype, Mol. Cell. Biol. 16, 5691-5700.
38. Wang, D., Stravopodis, D., Teglund, S., Kituzawa, J. & Ihle, J. N. (1996) Naturally occurring dominant negative variants of Stat5, Mol. Cell. Biol. 16, 6141-6148.
39. Sasse, J., Hemmann, U., Schwanz, C., Schniertshauer, U., Heesel, B., Landgraf, C., Schneidermergener, J., Heinrich, P. C. & Horn. F. (1997) Mutational analysis of acute-phase response factor Stat3 activation and dimerization, Mol. Cell. Biol. 17, 4677-4686.
40. Pezet, A., Ferrag, F., Kelly, P. A. & Edery, M. (1997) Tyrosine docking sites of the rat prolactin receptor required for association and activation of Stat5, J. Biol. Chem. 272, 25043-25050.
41. Gouilleux, F., Pallard, C., Dusanter-Fourt, I., Wakao, H., Haldosen, L. A., Norstedt, G., Levy, D. & Groner, B. (1995) Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO J. 14, 2005-2013.
42. Clarke, D. L. & Linzer, D. I. (1993) Changes in prolactin receptor expression during pregnancy in the mouse ovary, Endocrinology 133, 224-232.
43. Shirota, M., Banville, D., Ali, S., Jolicoeur, C., Boutin, J. M., Edery, M., Djiane, J. & Kelly, P. A. (1990) Expression of two forms of prolactin receptor in rat ovary and liver, Mol. Endocrinol. 4, 1136-1143.
44. Edery, M., Jolicoeur, C., Levi-Meyrueis, C., Dusanter-Fourt, I., Petridou, B., Boutin, J. M., Lesueur, L., Kelly, P. A. & Djiane, J. (1989) Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland, Proc. Natl Acad. Sci. USA 86, 2112-2116.
45. Chen, X. J. & Horseman, N. D. (1994) Cloning, expression, and mutational analysis of the pigeon prolactin receptor. Endocrinology 135, 269-276.