SCOPUS 정보 검색 플랫폼

Volumn 61, Issue 1, 1998, Pages 23-31

A convenient method for library construction: Parallel synthesis of β- amino ester and quinoline derivatives in liquid phase using Ln(OTf)3- catalyzed three-component reactions

(3) Kobayashi, Shu a Komiyama, Susumu a Ishitani, Haruro a

a NONE

Author keywords

amino ester; Ln(OTf)3; Quinoline derivatives; Three component reactions

Indexed keywords

ALDEHYDES; AMINES; CATALYSIS; CATALYSTS; DERIVATIVES; ESTERS; LANTHANUM COMPOUNDS; OLEFINS; PURIFICATION;

AMINO ESTER; LANTHANIDE TRIFLATE; LEWIS ACID; QUINOLINES; SOLUTION PHASE SYNTHESIS;

BIOSYNTHESIS;

LANTHANIDE; QUINOLINE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; COLUMN CHROMATOGRAPHY; DIASTEREOISOMER; DRUG SYNTHESIS; FILTRATION; MASS SPECTROMETRY; MELTING POINT; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0032403265 PISSN: 00063592 EISSN: None Source Type: Journal
DOI: 10.1002/(SICI)1097-0290(199824)61:1<23::AID-BIT7>3.0.CO;2-0 Document Type: Article

Times cited : (27)

References (60)

1
- 0028757621
- (a) Ugi, I.; Dömling, A.; Hörl, W. Endeavour 1994, 18, 115.
- (1994) Endeavour , vol.18 , pp. 115
- Ugi, I.¹ Dömling, A.² Hörl, W.³

2
- 0000512227
- (b) Armstrong, R.; Combs, A. P.; Tempest, P. A.; Brown, S. D.; Keating, T. A. Acc. Chem. Res. 1996, 29, 123.
- (1996) Acc. Chem. Res. , vol.29 , pp. 123
- Armstrong, R.¹ Combs, A.P.² Tempest, P.A.³ Brown, S.D.⁴ Keating, T.A.⁵

3
- 33748220036
- (c) Tempest, P. A.; Brown, S. D.; Armstrong, R. W. Angew. Chem., Int. Ed. Engl. 1996, 35, 640.
- (1996) Angew. Chem., Int. Ed. Engl. , vol.35 , pp. 640
- Tempest, P.A.¹ Brown, S.D.² Armstrong, R.W.³

4
- 0028827034
- (d) Wipf, P.; Cunningham, A. Tetrahedron Lett. 1995, 36, 7819.
- (1995) Tetrahedron Lett. , vol.36 , pp. 7819
- Wipf, P.¹ Cunningham, A.²

5
- 0030603133
- (e) Ugi, I.; Demharter, A.; Hörl, W.; Schmid, T. Tetrahedron 1996, 52, 11657.
- (1996) Tetrahedron , vol.52 , pp. 11657
- Ugi, I.¹ Demharter, A.² Hörl, W.³ Schmid, T.⁴

6
- 85047672030
- (a) Kobayashi, S.; Araki, M.; Yasuda, M. Tetrahedron Lett. 1995, 36, 5773.
- (1995) Tetrahedron Lett. , vol.36 , pp. 5773
- Kobayashi, S.¹ Araki, M.² Yasuda, M.³

7
- 0000005220
- (b) Kobayashi, S.; Ishitani, H.; Nagayama, S. Chem. Lett. 1995, 423.
- (1995) Chem. Lett. , pp. 423
- Kobayashi, S.¹ Ishitani, H.² Nagayama, S.³

8
- 0030477258
- (a) Balkenhohl, F.; von dem Bussche-Hünnefeld, C.; Lansky, A.; Zechel, C. Angew. Chem., Int. Ed. Engl. 1996, 35, 2288.
- (1996) Angew. Chem., Int. Ed. Engl. , vol.35 , pp. 2288
- Balkenhohl, F.¹ Von Dem Bussche-Hünnefeld, C.² Lansky, A.³ Zechel, C.⁴

9
- 7044263277
- (b) Thompson, L.A.; Ellman, J. A. Chem. Rev. 1996, 96, 555.
- (1996) Chem. Rev. , vol.96 , pp. 555
- Thompson, L.A.¹ Ellman, J.A.²

10
- 33748237769
- (c) Früchtel, J. S.; Jung, G. Angew. Chem., Int. Ed. Engl. 1996, 35, 17.
- (1996) Angew. Chem., Int. Ed. Engl. , vol.35 , pp. 17
- Früchtel, J.S.¹ Jung, G.²

11
- 0029065615
- (d) Terrett, N. K.; Gardner, M.; Gordon, D. W.; Kobylecki, R. J.; Steele, J. Tetrahedron 1995, 51, 8135.
- (1995) Tetrahedron , vol.51 , pp. 8135
- Terrett, N.K.¹ Gardner, M.² Gordon, D.W.³ Kobylecki, R.J.⁴ Steele, J.⁵

12
- 0000951871
- (e) Lowe, G. Chem. Soc. Rev. 1995, 37, 309.
- (1995) Chem. Soc. Rev. , vol.37 , pp. 309
- Lowe, G.¹

13
- 0028243847
- (f) Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233.
- (1994) J. Med. Chem. , vol.37 , pp. 1233
- Gallop, M.A.¹ Barrett, R.W.² Dower, W.J.³ Fodor, S.P.A.⁴ Gordon, E.M.⁵

14
- 0028318863
- (g) Gordon, E. M.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gallop, M. A. J. Med. Chem. 1994, 37, 1385.
- (1994) J. Med. Chem. , vol.37 , pp. 1385
- Gordon, E.M.¹ Barrett, R.W.² Dower, W.J.³ Fodor, S.P.A.⁴ Gallop, M.A.⁵

15
- 0029074627
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1995) Proc. Natl. Acad. Sci. , vol.92 , pp. 6419
- Han, H.¹ Wolfe, M.M.² Brenner, S.³ Janda, K.D.⁴

16
- 0029988589
- See also
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 2539
- Han, H.¹ Janda, K.D.²

17
- 0015529625
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1972) Nature , vol.237 , pp. 512
- Bayer, E.¹ Mutter, M.²

18
- 0025354607
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1990) Nucleic Acids Res. , vol.18 , pp. 3155
- Bonora, G.M.¹ Scremin, C.L.² Colonna, F.P.³ Garbesi, A.⁴

19
- 0001686537
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1991) J. Am. Chem. Soc. , vol.113 , pp. 5095
- Douglas, S.P.¹ Whitfield, D.M.² Krepinsky, J.J.³

20
- 0029810688
- Successful examples of library construction or methods for library construction in liquid-phase have been reported. (a) Han, H.; Wolfe, M. M.; Brenner, S.; Janda, K. D. Proc. Natl. Acad. Sci. 1995, 92, 6419. (b) Han, H.; Janda, K. D. J. Am. Chem. Soc. 1996, 118, 2539. See also, (c) Bayer, E.; Mutter, M. Nature 1972, 237, 512. (d) Bonora, G. M.; Scremin, C. L.; Colonna, F. P.; Garbesi, A. Nucleic Acids Res. 1990, 18, 3155. (e) Douglas, S. P.; Whitfield, D. M.; Krepinsky, J. J. J. Am. Chem. Soc. 1991, 113, 5095. (f) Kim, R. M.; Manna, M.; Hutchins, S. M.; Griffin, P. R.; Yates, N. A.; Bernick, A. M.; Chapman, K. T. Proc. Natl. Acad. Sci. 1996, 93, 10012.
- (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 10012
- Kim, R.M.¹ Manna, M.² Hutchins, S.M.³ Griffin, P.R.⁴ Yates, N.A.⁵ Bernick, A.M.⁶ Chapman, K.T.⁷

21
- 0029813591
- (a) Kobayashi, S.; Nagayama, S. J. Am. Chem. Soc. 1996, 118, 8977.
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 8977
- Kobayashi, S.¹ Nagayama, S.²

22
- 0029883736
- (b) Kobayashi, S.; Hachiya, I.; Suzuki, S.; Moriwaki, M. Tetrahedron Lett. 1996, 37, 2809.
- (1996) Tetrahedron Lett. , vol.37 , pp. 2809
- Kobayashi, S.¹ Hachiya, I.² Suzuki, S.³ Moriwaki, M.⁴

23
- 0030605818
- (c) Kobayashi, S.; Hachiya, I.; Yasuda, M. Tetrahedron Lett. 1996, 37, 5569.
- (1996) Tetrahedron Lett. , vol.37 , pp. 5569
- Kobayashi, S.¹ Hachiya, I.² Yasuda, M.³

24
- 0030597207
- (d) Kobayashi, S.; Moriwaki, M.; Akiyama, R.; Suzuki, S.; Hachiya, I. Tetrahedron Lett. 1996, 37, 7783.
- (1996) Tetrahedron Lett. , vol.37 , pp. 7783
- Kobayashi, S.¹ Moriwaki, M.² Akiyama, R.³ Suzuki, S.⁴ Hachiya, I.⁵

25
- 0030590980
- (e) Kobayashi, S.; Nagayama, S.; Busujima, T. Tetrahedron Lett. 1996, 37, 9221.
- (1996) Tetrahedron Lett. , vol.37 , pp. 9221
- Kobayashi, S.¹ Nagayama, S.² Busujima, T.³

26
- 0344724351
- Trost, B. M., Ed.; Pergamon Press: Oxford, Chapter 4.1
- Cf. Kleinnman, E. F. In Comprehensive Organic Synthesis; Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 2, Chapter 4.1.
- (1991) Comprehensive Organic Synthesis , vol.2
- Kleinnman, E.F.¹

27
- 0029135125
- Kobayashi, S.; Ishitani, H.; Nagayama, S. Synthesis 1995, 1195.
- (1995) Synthesis , pp. 1195
- Kobayashi, S.¹ Ishitani, H.² Nagayama, S.³

28
- 0000730407
- Trost, B. M., Ed.; Pergamon Press: Oxford
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1991) Comprehensive Organic Synthesis , vol.5 , pp. 401
- Weinreb, S.M.¹

29
- 0003719612
- Academic Press: San Diego, Chapters 2 and 9
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1987) Hetero Diels-Alder Methodology in Organic Synthesis
- Boger, D.L.¹ Weinreb, S.M.²

30
- 0010481046
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1988) J. Org. Chem. , vol.53 , pp. 2251
- Lucchini, V.¹ Prato, M.² Scorrano, G.³ Tecilla, P.⁴

31
- 45449097286
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1983) L. Tetrahedron , vol.39 , pp. 2869
- Boger, D.¹

32
- 0001595120
- and references cited therein
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1988) Tetrahedron Lett. , vol.29 , pp. 5855
- Grieco, P.A.¹ Bahsas, A.²

33
- 0003043326
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1967) Tetrahedron Lett. , pp. 4199
- Joh, T.¹ Hagihara, N.²

34
- 0000354729
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1967) Russian Chem. Rev. , vol.36 , pp. 656
- Povarov, L.S.¹

35
- 84986499164
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1970) J. Heterocyclic Chem. , vol.7 , pp. 1353
- Worth, D.F.¹ Perricine, S.C.² Elslager, E.F.³

36
- 0000668693
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1986) Heterocycles , vol.24 , pp. 3385
- Kametani, T.¹ Takeda, H.² Suzuki, Y.³ Kasai, H.⁴ Honda, T.⁵

37
- 33845378747
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1985) J. Org. Chem. , vol.56 , pp. 5678
- Cheng, Y.S.¹ Ho, E.² Mariano, P.S.³ Ammon, H.L.⁴

38
- 0000128579
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1993) Heterocycles , vol.35 , pp. 1039
- Narasaka, K.¹ Shibata, T.²

39
- 0029123197
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1995) Synthesis , pp. 801
- Makioka, Y.¹ Shindo, T.² Taniguchi, Y.³ Takaki, K.⁴ Fujiwara, Y.⁵

40
- 33845378798
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1985) J. Am. Chem. Soc. , vol.107 , pp. 1768
- Larsen, S.D.¹ Grieco, P.A.²

41
- 0023802576
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1988) J. Org. Chem. , vol.53 , pp. 3325
- Grieco, P.A.¹ Parker, D.T.²

42
- 0001153217
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1989) Tetrahedron Lett. , vol.30 , pp. 3037
- Sisko, J.¹ Weinreb, S.M.²

43
- 0002654125
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1978) Chem. Lett. , pp. 267
- Nomura, Y.¹ Kimura, M.² Takeuchi, Y.³ Tomoda, S.⁴

44
- 0022398567
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1985) Tetrahedron Lett. , vol.26 , pp. 5983
- Danishefsky, S.¹ Langer, M.E.² Vogel, C.³

45
- 49049133282
- Cf. (a) Weinreb, S. M. In Comprehensive Organic Synthesis, Trost, B. M., Ed.; Pergamon Press: Oxford, 1991; Vol. 5, p 401. (b) Boger, D. L.; Weinreb, S. M. Hetero Diels-Alder Methodology in Organic Synthesis, Academic Press: San Diego, 1987, Chapters 2 and 9. (c) Lucchini, V.; Prato, M.; Scorrano, G.; Tecilla, P. J. Org. Chem. 1988, 53, 2251. (d) Boger, D. L. Tetrahedron 1983, 39, 2869. (e) Grieco P. A.; Bahsas, A. Tetrahedron Lett. 1988, 29, 5855, and references cited therein. (f) Joh, T.; Hagihara, N. Tetrahedron Lett. 1967, 4199. (g) Povarov, L. S. Russian Chem. Rev. 1967, 36, 656. (h) Worth, D. F.; Perricine, S. C.; Elslager, E. F. J. Heterocyclic Chem. 1970, 7, 1353. (i) Kametani, T.; Takeda, H.; Suzuki, Y.; Kasai, H.; Honda, T. Heterocycles 1986, 24, 3385. (j) Cheng, Y. S.; Ho, E.; Mariano, P. S.; Ammon, H. L. J. Org. Chem. 1985, 56, 5678. (k) Narasaka, K.; Shibata, T. Heterocycles 1993, 35, 1039. (l) Makioka, Y.; Shindo, T.; Taniguchi, Y.; Takaki, K.; Fujiwara, Y. Synthesis 1995, 801. (m) Larsen, S. D.; Grieco, P. A. J. Am. Chem. Soc. 1985, 107, 1768. (n) Grieco, P. A.; Parker, D. T. J. Org. Chem. 1988, 53, 3325. (o) Sisko, J.; Weinreb, S. M. Tetrahedron Lett. 1989, 30, 3037. (p) Nomura, Y.; Kimura, M.; Takeuchi, Y.; Tomoda, S. Chem. Lett. 1978, 267. (q) Danishefsky, S.; Langer, M. E.; Vogel, C. Tetrahedron Lett. 1985, 26, 5983. (r) Danishefsky, S.; Karwin, Jr., J. F. Tetrahedron Lett. 1982, 23, 3739.
- (1982) Tetrahedron Lett. , vol.23 , pp. 3739
- Danishefsky, S.¹ Karwin Jr., J.F.²

46
- 85064667331
- and references cited therein
- Kobayashi, S. Synlett 1994, 689, and references cited therein.
- (1994) Synlett , pp. 689
- Kobayashi, S.¹

47
- 0345154713
- note
- 3) also worked well in these reactions.

48
- 0002897799
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) J. Chem. Soc., Chem. Commun. , pp. 183
- Kawada, A.¹ Mitamura, S.² Kobayashi, S.³

49
- 0001044209
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) J. Org. Chem. , vol.61 , pp. 1902
- Ishitani, H.¹ Nagayama, S.² Kobayashi, S.³

50
- 0001017480
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) J. Org. Chem. , vol.61 , pp. 2256
- Kobayashi, S.¹ Nagayama, S.²

51
- 0029994914
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) Tetrahedron Lett. , vol.37 , pp. 3731
- Kobayashi, S.¹ Ishitani, H.² Komiyama, S.³ Oniciu, D.C.⁴ Katritzky, A.R.⁵

52
- 0030498167
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) Carbohydr. Lett. , vol.2 , pp. 157
- Hashizume, N.¹ Kobayashi, S.²

53
- 0030573985
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1996) Tetrahedron Lett. , vol.37 , pp. 7357
- Ishitani, H.¹ Kobayashi, S.²

54
- 0000568181
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1997) Bull. Chem. Soc. Jpn. , vol.70 , pp. 267
- Kobayashi, S.¹ Moriwaki, M.² Hachiya, I.³

55
- 0002794514
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1997) Synlett , pp. 115
- Kobayashi, S.¹ Ishitani, H.² Ueno, M.³

56
- 0000050581
- For a recent example, (a) Kawada, A.; Mitamura, S.; Kobayashi, S. J. Chem. Soc., Chem. Commun. 1996, 183. (b) Ishitani, H.; Nagayama, S.; Kobayashi, S. J. Org. Chem. 1996, 61, 1902. (c) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1996, 61, 2256. (d) Kobayashi, S.; Ishitani, H.; Komiyama, S.; Oniciu, D. C.; Katritzky, A. R. Tetrahedron Lett. 1996, 37, 3731. (e) Hashizume, N.; Kobayashi, S. Carbohydr. Lett. 1996, 2, 157. (f) H. Ishitani, H.; Kobayashi, S. Tetrahedron Lett. 1996, 37, 7357. (g) Kobayashi, S.; Moriwaki, M.; Hachiya, I. Bull. Chem. Soc. Jpn. 1997, 70, 267. (h) Kobayashi, S.; Ishitani, H.; Ueno, M. Synlett 1997, 115. (i) Kobayashi, S.; Nagayama, S. J. Org. Chem. 1997, 62, 232.
- (1997) J. Org. Chem. , vol.62 , pp. 232
- Kobayashi, S.¹ Nagayama, S.²

57
- 0344292343
- U.S. Patent 3615169, 1971; CA 1972, 76, 5436a
- (a) Thom, K. F. U.S. Patent 3615169, 1971; CA 1972, 76, 5436a.
- Thom, K.F.¹

58
- 0001008984
- (b) Forsberg, J. H.; Spaziano, V. T.; Balasubramanian, T. M.; Liu, G. K.; Kinsley, S. A.; Duckworth, C. A.; Poteruca, J. J.; Brown, P. S.; Miller, J. L. J. Org. Chem. 1987, 52, 1017.
- (1987) J. Org. Chem. , vol.52 , pp. 1017
- Forsberg, J.H.¹ Spaziano, V.T.² Balasubramanian, T.M.³ Liu, G.K.⁴ Kinsley, S.A.⁵ Duckworth, C.A.⁶ Poteruca, J.J.⁷ Brown, P.S.⁸ Miller, J.L.⁹

59
- 0027262676
- Kobayashi, S.; Hachiya, I.; Araki, M.; Ishitani, H. Tetrahedron Lett. 1993, 34, 3755.
- (1993) Tetrahedron Lett. , vol.34 , pp. 3755
- Kobayashi, S.¹ Hachiya, I.² Araki, M.³ Ishitani, H.⁴

60
- 33751157649
- Kobayashi, S.; Hachiya, I. J. Org. Chem. 1994, 59, 3590.
- (1994) J. Org. Chem. , vol.59 , pp. 3590
- Kobayashi, S.¹ Hachiya, I.²

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