Application of polymer-bound phosphonium salts as traceless supports for solid phase synthesis

Tetrahedron Letters

Volumn 37, Issue 42, 1996, Pages 7595-7598

  Hughes, Ian ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; INDOLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; TECHNIQUE;

EID: 0030583495     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01669-3     Document Type: Article

References (14)

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2. 2. Hermkens, P.H.H.; Ottenheijm, H.C.J.; Rees, D. Tetrahedron, 1996, 52, 4527.
3. 3. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J., Steele, J. Tetrahedron, 1995, 51, 8135.
4. 4. Plunkett, M.J.; Ellman, J.A. J. Org. Chem. 1995, 6006.
5. 5. Chenera, B.; Finkelstein, J.A.; Veber, D.F. J. Am. Chem. Soc. 1995, 11999.
6. 6. Sucholeiki, I. Tetrahedron Lett. 1994, 35, 7307.
7. 7. Johnson, C.R.; Zhang, B. Tetrahedron Lett. 1995, 36, 9253.
8. 8. Ford, W.T. in ACS Symposium Series 308: Polymeric Reagents and Catalysts, Ford, W.T., Ed.; ACS, Washington, 1986, pp155-185.
9. 9. Clarke, S.D.; Harrison, C.R.; Hodge, P. Tetrahedron Lett. 1980, 21, 1375.
10. 10. Fluka, Triphenylphosphine polymer bound, ∼3 mmol triphenylphosphine/g resin (catalogue no. 93093).
11. 11. Bernard, M.; Ford, W.T. J. Org. Chem. 1983, 48, 326.
12. 12. Girard, A.; Sandulesco, G. Helv. Chim. Acta, 1936, 19, 1095.
13. 3) 3.86 (3 H, s), 6.71 (1 H, d, J = 3 Hz), 6.98 (2 H, d, J = 8 Hz), 7.12 (2 H, m), 7.39 (1 H, d, J = 8 Hz), 7.60 (3 H, d, J = 8 Hz) and 8.25 (1 H, br s). HRMS (EI): Calculated, 223.0997; Observed, 223.1014.
14. 14. Le Corre, M.; Hercourt, A.; Le Baron, H. J. Chem. Soc., Chem. Commun. 1981, 14.