External and internal calibration of the MHC class I-specific receptor Ly49A on murine natural killer cells

Journal of Immunology

Volumn 161, Issue 11, 1998, Pages 6133-6138

  Kåse, Anna ^a   Johansson, Maria H ^a   Olsson Alheim, Mats Y ^a   Kärre, Klas ^a   Höglund, Petter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ADAPTATION; ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; DRUG RECEPTOR BINDING; KILLER CELL; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, LY; ANTIGENS, SURFACE; CALIBRATION; CARRIER PROTEINS; CELL COMMUNICATION; CELLS, CULTURED; COCULTURE TECHNIQUES; DOWN-REGULATION; H-2 ANTIGENS; INTERLEUKIN-2; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOSAICISM; RECEPTORS, IMMUNOLOGIC;

EID: 0032400976     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Sentman, C. L., J. Hackett, V. Kumar, and M. Bennett. 1989. H-2/Hh-1 specific subsets of murine natural killer cells mediate rejection of bone marrow grafts. J. Exp. Med 170:191.
2. + IL-2-activated natural killer cells. Nature 358: 66.
3. Mason, L. H., J. R. Ortaldo, H. A. Young, V. Kumar, M. Bennett, and S. K. Anderson. 1995. Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family. J. Exp. Med 183: 293.
4. Brennan, J., S. Lemieux, J. D. Freeman, D. I. Mager, and F. Takei. 1996. Heterogeneity among Ly-49C natural killer cells: characterization of highly related receptors with differing functions and expression patterns. J. Exp. Med. 184:2085.
5. Brown, M. G., A. A. Scalzo, K. Matsumoto, and W. M. Yokoyama. 1997. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155:53.
6. Held, W., and Raulet, D. H. 1997. Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development. J. Exp. Med. 185:2079.
7. Ljunggren, H.-G., and K. Kärre. 1990. In search of the "missing self": MHC molecules and NK cell recognition. Immunol. Today 11:237.
8. Ljunggren, H.-G., and K. Kärre. 1985. Host resistance directed selectively against H-2-deficient lymphoma variants: analysis of the mechanism. J. Exp. Med. 162: 1745.
9. Kärre, K., H.-G. Ljunggren, G. Piontek, and R. Kiessling. 1986. Selective rejection of H-2-deficient lymphoma variant suggests alternative immune defense strategy. Nature 319:675.
10. Storkus, W. J., J. Alexander, J. A. Payne, J. R. Dawson, and P. Cresswell. 1988. Reversal of natural killing susceptibility in target cells expressing transfected class I genes. Proc. Natl. Acad. Sci. USA 86:2361.
11. d transgene to C57BL mice. J. Exp. Med. 168:1469.
12. Öhlén, C., G. Kling, P. Höglund, M. Hansson, G. Scangos, C. Bieberich, G. Jay, and K. Kärre. 1989. Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice. Science 246:666.
13. Liao, N.-S., M. Bix, M. Zijlstfa, R. Jaenisch, and D. H. Raulet. 1991. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253:199.
14. - bone marrow in chimeric mice. Proc. Natl. Acad. Sci. USA 88:10332.
15. Olsson, M. Y., K. Kärre, and C. L. Sentman. 1995. Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc. Natl. Acad. Sci. USA 92: 1649.
16. low NK cells. J. Immunol. 159:3189.
17. Sundbäck, J., K. Kärre, and C. L. Sentman. 1996. Cloning of minimally divergent allelic forms of the natural killer (NK) receptor Ly49C, differentially controlled by host genes in the MHC and NK gene complexes. J. Immunol. 157:3936.
18. Salcedo, M., A. D. Diehl, M. Y. Olsson-Alheim, J. Sundbäck, L. Van Kaer, K. Kärre, and H.-G. Ljunggren. 1997. Altered expression of Ly49 inhibitory receptors on NK cells from MHC class I deficient mice. J. Immunol. 158:3147.
19. Held, W., J. R. Dorfman, M.-F. Wu, and D. H. Raulet. 1996. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur. J. Immunol. 26:2286.
20. Fahlén, L., N. K. S. Khoo, M. R. Daws, and C. L. Sentman. Location-specific regulation of transgenic Ly49A receptors by major histocompatibility complex class I molecules. Eur. J. Immunol. 27:2057.
21. Sentman, C. L., M. Y. Olsson, and K. Kärre. 1995. Missing self recognition by natural killer cells in MHC class I transgenic mice: a "receptor calibration" model for how effector cells adapt to self. Semin. Immunol. 7:109.
22. Johansson, M. H., C. Bieberich, G. Jay, K. Kärre, and P. Höglund. 1997. Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene. J. Exp. Med. 186:353.
23. Chadwick, B. S., and R. G. Miller. 1992. Hybrid resistance in vitro: possible role of both class 1 MHC and self peptides in determining the level of target cell sensitivity. J. Immunol. 148:2307.
24. Sentman, C. L., M. Y. Olsson, M. Salcedo, P. Höglund, U. Lendahl, and K. Kärre. 1994. H-2 allele-specific protection from NK cell lysis in vitro for lymphoblasts but not tumor targets: protection mediated by α1/α2 domains. J Immunol. 153:5482.
25. Sykes, M., M. W. Harty, F. M. Karlhofer, D. A. Pearson, G. Szot, and W. Yokoyama. 1993. Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation. J. Exp. Med. 178:223.
26. Karlhofer, F. M., R. Hunziker, A. Reichlin, D. H. Margulies, and W. M. Yokoyama. 1994. Host MHC class I molecules modulate in vivo expression of a NK cell receptor. J. Immunol. 153:2407.
27. Bennett, M. 1987. Biology and genetics of hybrid resistance. Adv. Immunol. 41:333.
28. Rembecki, R. M., V. Kumar, C. David, and M. Bennett. 1988. Bone marrow cell transplants involving intra-H-2 recombinant inbred mouse strains: evidence that hemopoietic histocompatibility-I (Hh-1) genes are distinct from H-2D or H-2L. J. Immunol. 141:2253.
29. d transgene. J. Immunol. 156:2423.
30. Andersson M., S. Freland, M. H. Johansson, R. Wallin, J. K. Sandberg, B. J. Chambers, B. Christensson, U. Lendahl, S. Lemieux, M. Salcedo, and H.-G. Ljunggren. MHC class I mosaic truce reveal insights into control of Ly49C inhibitory receptor expression in NK cells. J. Immunol., In press.