Biometric evaluation of the ATC method for the determination of the acute dermal toxicity of chemicals

Biometrical Journal

Volumn 40, Issue 8, 1998, Pages 979-991

  Diener, W ^a  

^a Fed Inst Hlth Protect Consumers   (Germany)

Author keywords

ATC method; Classification probabilities; LD50 test; Probit model

Indexed keywords

TOXICITY;

ACUTE TOXIC CLASS METHOD; BIOMETRIC EVALUATION; CLASSES METHODS; CLASSIFICATION PROBABILITY; CLASSIFICATION SYSTEM; DOSE RESPONSE RELATIONSHIPS; EUROPEAN UNION; LD50 TEST; PROBIT MODELS; STEPWISE PROCEDURE;

ANIMALS;

EID: 0032280148     PISSN: 03233847     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4036(199812)40:8<979::AID-BIMJ979>3.0.CO;2-D     Document Type: Article

References (10)

1. DIENER, W., SICCHA, L., MISCHKE, U., KAYSER, D., and SCHLEDE, E., 1994: The Biometric Evaluation of the Acute-toxic-class Method (oral). Arch Toxicol 68, 599-610.
2. DIENER, W., MISCHKE, U., KAYSER, D., and SCHLEDE, E., 1995: The Biometric Evaluation of the OECD Modified Version of the Acute Toxic Class Method (oral). Arch Toxicol 69, 729-734.
3. DIENER, W., KAYSER, D., and SCHLEDE, E., 1997: The Inhalation Acute Toxic Class Method: Test Procedure and Biometric Evaluations. Arch Toxicol 71, 537-549.
4. DIENER, W., KAYSER, D., and SCHLEDE, E., 1998: The Dermal Acute Toxic Class Method: Test Procedure and Biometric Evaluations. Arch Toxicol 72 (in press).
5. EU Guideline 96/54/EEC, 1996: Official Journal of the European Communities L 248, September 30, 1996. B.1 tris Acute Toxicity (oral) - Acute toxic class method.
6. FINNEY, D.J., 1971: Probit analysis. 3rd edition. Cambridge University Press, Cambridge.
7. OECD, 1987: Guideline for testing of chemicals No. 402: Acute dermal toxicity. OECD, Paris.
8. OECD, 1996: Guideline for testing of chemicals No. 423: Acute oral toxicity - Acute Toxic Class Method, OECD, Paris.
9. SCHLEDE, E., MISCHKE, U., DIENER, W., and KAYSER, D., 1995: The international validation study of the acute toxic class method (oral). Arch Toxicol 69, 659-670.
10. UNKELBACH, H.D. and WOLF, T., 1985: Qualitative Dosis-Wirkungs-Analysen. Gustav Fischer Verlag, Stuttgart, New York.