Evidence for arylamine N-acetyltransferase activity in the bacterium Helicobacter pylori

Toxicology Letters

Volumn 91, Issue 1, 1997, Pages 63-71

  Chung, J G ^a   Wang, H H ^b   Tsou, M F ^b   Hsieh, S E ^c   Lo, H H ^c   Yen, Y S ^a   Chang, S S ^a   Wu, L T ^a   Lee, J H ^b   Hung, C F ^d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c Chungtai Junior College of Medical Technology   (Taiwan)

^d JEN AI HOSPITAL   (Taiwan)

Author keywords

2 Aminofluorene; Helicobacter pylori; N Acetyl p aminobenzoic acid; N Acetyl2 aminofluorene; N Acetyltransferase; p Aminobenzoic acid

Indexed keywords

2 FLUORENYLAMINE; 4 AMINOBENZOIC ACID; ARYLAMINE ACETYLTRANSFERASE; EDETIC ACID; IODOACETAMIDE; N (2 FLUORENYL)ACETAMIDE;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HELICOBACTER PYLORI; HUMAN; NONHUMAN; PH; PRIORITY JOURNAL; TEMPERATURE;

4-AMINOBENZOIC ACID; ACETYL COENZYME A; ACETYLATION; ARYLAMINE N-ACETYLTRANSFERASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; ENZYME INHIBITORS; FLUORENES; HELICOBACTER PYLORI; HUMANS; HYDROGEN-ION CONCENTRATION; IODOACETAMIDE; KINETICS; PROTEASE INHIBITORS; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 0031567104     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)03870-8     Document Type: Article

References (43)

1. [1] Dybing, E. and Huitfield, M.S. (1992) Species Differences in Carcinogen Metabolism and Interspecies Extrapolution. IARC Scientific Publication No. 116. IARC, Lyons, pp. 501-522.
2. [2] Holme, J.A., Trygg, B. and Sederlund, E. (1986) Species differences in the metabolism of 2-acetylaminofluorene by hepatocytes in primary monolayer culture. Cancer Res. 46, 1627-1632.
3. [3] Langenbach, R., Rudo, K., Ellis, S., Hir, C. and Nesnow, S. (1987) Species variation in bladder cell and liver cell activation of acetylaminofluorene. Cell Biol. Toxicol. 3, 303-317.
4. [4] Weber, W.W. and Hein, D.W. (1985) N-Acetylation pharmacogenetics. Pharmacol. Rev. 37, 25-79.
5. [5] Weber, W.W. (1987) The Acetylator Genes and Drug Response. Oxford University Press, New York.
6. [6] Hein, D.W., Ruston, T.D., Ferguson, R.T., Doll, M.A. and Gray, K. (1994) Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferase. Arch. Toxicol. 68, 129-133.
7. [7] Cartwright, R.A., Glasham, R.W., Rogers, H.J., Ahmad, R.A., Barham-Hall, D., Higgins, E. and Kaha, M.A. (1982) The role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer. Lancet ii, 842-846.
8. [8] Lang, N.P., Chu, D.Z.J., Hunter, C.F., Kendall, D.C., Flammang, J.J. and Kadlubar, F.F. (1987) Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. Surg. 121, 1259-1261.
9. [9] Ilett, K.K., David, B.M., Detchon, P., Castledon, W.M. and Kwa, R. (1987) Acetylator phenotype in colorectal carcinoma. Cancer Res. 47, 1466-1469.
10. [10] Einisto, P., Watanabe, M., Ishidate, M. and Nohmi, T. (1991) Mutagenicity of 30 chemicals in S. typhimurium possessing different nitroreductase or O-acetyltransferase activities. Mutat. Res. 259, 95-102.
11. [11] Warren, J.R. and Marshall. B.J. (1983) Unidentifield curved bacilli on gastric epithelium in active chronic gastritis. Lancet i, 1273-1275.
12. [12] Rauws, E.A.J., Langenberg, W. and Houthaff, H.J. (1988) Camplobacter pylori associated chronic active antral gastritis: A prospective study of its prevalence and the effects of antibacteriial and antiucler treatment. Gastroenterol. 94, 33-40.
13. [13] Normura, A., Stemmermann, G.N. and P-Chyou, K. (1991) Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N. Engl. J. Med. 325, 1132-1136.
14. [14] Parsonnet, J., Friedman, G.D. and Vandersteen, D.P. (1991) Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325, 1127-1131.
15. [15] Kato, J., Tominaga, S. and Ito, Y. (1992) A prospective study of atrophic gastritis and stomach cancer risk. Jpn. J. Cancer Res. 83, 1137-1142.
16. [16] Marshall, B. (1986) Campylobacter pylori and gastritis. J. Infect. Dis. 153, 650-657.
17. [17] Dixon, M.F. (1989) Campylobacter pylori and Chronic Gastritis. Campylobacter pylori and Gastroduodenal Disease. Blackwell Scientific, Oxford, pp. 106-116.
18. [18] Marshall, B., Goodwin, C.S. and Warren, J.R. (1988) Prospective double-blind trial of duodenal ucler relapse after eradication of Campylobacter pylori. Cancel. 2, 1437-1447.
19. [19] Tannen, R.H. and Weber, W.W. (1980) Inheritance of acetylator phenotype in mice. J. Pharmacol. Exp. Therap. 213, 480-484.
20. [20] Hein, D.W., Omichinski, J.G., Brewer, J.A. and Weber, W.W. (1982) A unique pharmacogenetic expression of the N-acetylation polymorphism in the inbred hamster. J. Pharmacol. Exp. Therap. 220, 8-15.
21. [21] Hein, D.W., Smolen, T.N., Fox, R.R. and Weber, W.W. (1982) Identification of genetically homozgous rapid and slow acetylators of drugs and environmental carcinogens among established inbred rabbit strains. J. Pharmacol. Exp. Therap. 223, 40-44.
22. [22] Andres, H.H., Kolb, H.J. and Weiss, L. (1983) Purification and physical-chemical properties of acetyl-CoA: arylamine N-acetyltransferase from pigeon liver. Biochim. Biophys. Acta 746, 182-192.
23. [23] Ho, C.C., Lin, T.H., Lai, Y.S., Chung, J.G., Levy, G.N. and Weber, W.W. (1996) Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from rapid and slow acetylator frog tissues. Drug Metab. Dispos. 24, 137-141.
24. [24] Dewhurst, S.A., Croker, S.G., Ikeda, K. and McCaman, R. E. (1972) Metabolism of biogenic amines in Drosophila nervous tissue. Comp. Biochem. Physiol. 43B, 975-981.
25. [25] Whitaker, D.P. and Goosey, M.W. (1993) Purification and properties of the enzyme arylamine N-acetyltransferase from the housfly Musca domestica. Biochem. J. 295, 149-154.
26. [26] Chung, J.G., Kuo, H.M., Lin, T.H., Ho, C.C., Lee, J.H., Lai, J.M., Levy, G.N. and Weber, W.W. (1996) Evidence for arylamine N-acetyltransferase in the Nematode Anisakis simplex. Cancer Lett. 106, 1-8.
27. [27] Ho, C.C., Lai, J.M., Shih, M.C. and Chung, J.G. (1996) Kinetics of acetyl coenzyme A:arylamine N-acetyltransferase from rapid and slow acetylator fish tissues. J. Pharmacol. Exp. Therap., submitted.
28. [28] Watanabe, M., Sofuni, T. and Nohmi, T. (1992) Involvement of Cys69 residue in the catalytic mechanism of N-hydroxylamine O-acetyltransferase of Salmonella typhimurium: sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and higher organisms. J. Biol. Chem. 267, 8429-8436.
29. [29] Chung, J.G., Levy, G.N. and Weber, W.W. (1993) Distribution of 2-aminofluorene and p-aminobenzoic acid N-acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-Nats slow acetylator congenic mice. Drug Metab. Dispos. 21, 1057-1063.
30. [30] Andres, H.H., Klem, A.J., Szabo, S.M. and Weber, W.W. (1985) New spectrophotometric and radiochemical assays for acetyl-CoA:arylamine N-acetyltransferase applicable to a wide variety of arylamines. Anal. Biochem. 145, 367-375.
31. [31] Mattano, S.S. and Weber, W.W. (1987) Kinetics of arylamine N-acetyltransferase in tissues from rapid and slow acetylator mice. Carcinogenesis 8, 133-137.
32. [32] Martell, K.J., Levy, G., N.G.N. and Weber, W.W. (1992) Cloned mouse N-acetyltransferase: enzymatic properties of expressed Nat-1 and Nat-2 gene products. Mol. Pharmacol. 42, 265-272.
33. [33] Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
34. [34] Cleland, W.W. (1967) The statistical analysis of enzyme kinetics data. Adv. Enzymol. 29, 1-30.
35. [35] Andres, H.H., Vogel, R.S., Tarr, G.E., Johnson, L. and Weber, W.W. (1987) Purification, physicochemical, and kinetic properties of liver acetyl-CoA:arylamine N-acetyltransferase from rapid acetylator rabbits. Mol. Pharmacol. 31, 446-456.
36. [36] Vatsis, K.P. and Weber, W.W. (1996) The old/new genetics and human acetylator polymorphisms. Pharmacogenetics, in press.
37. [37] Vatsis, K.P. and Weber, W.W. (1993) Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 gene locus. Arch. Biochem. Biophys. 301, 71-76.
38. [38] Yamada, R. and Bradshaw, R.A. (1991) Rat liver polysome N-acetyltransferase: isolation and characterization. Biochem. 30, 1010-1016.
39. [39] Blum, M., Grant, D.M., Demierre, A. and Meyer, U.A. (1989) N-Acetylation pharmacogenetics: a gene deletion causes absence of arylamine N-acetyltransferase in livers od slow acetylator rabbits. Proc. Natl. Acad. Sci. USA 86, 9554-9557
40. [40] Hein, D.W., Kirlin, W.G., Ferguson, R.J. and Weber, W.W. (1985) Biochemical investigation of the basis for the genetic N-acetylation polymorphism in the inbred hamster. J. Pharmacol. Exp. Therap. 234, 358-364.
41. [41] Blum, M., Grant, D.M., McBride, O.W., Hein, M. and Meyer, U.A. (1990) Human arylamine N-acetyltransferase genes: isolation, characterization, chromosomal localization, and functional expression. DNA Cell Biol. 9, 193-203.
42. [42] Kelly, S.L. and Sim, E. (1994) Arylamine N-acetyltransferase in Balb/c mice: identification of a novel mouse isozyme by cloning and expression in vitro. Biochem. J. 302, 347-353.
43. [43] Mattano, S.S., Land, S., King, C.M. and Weber, W.W. (1989) Purification and biochemical characterization of hepatic arylamine N-acetyltransferase from rapid and slow acetylator mice: identity with arylhydroxamic acid N,O-acyltransferase and N-hydroxyarylamine O-acetyltransferase. Mol. Pharmacol. 35, 599-609.