Mechanisms and clinical implications of apoptosis

Hospital Medicine

Volumn 59, Issue 12, 1998, Pages 924-930

  Voss, M ^a,b   Cotton, M F ^a  

^a Department of Surgery ^*  (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CELL SURFACE RECEPTOR; DNA FRAGMENT; FAS ANTIGEN; LIPOCORTIN 5; PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; ELECTRON MICROSCOPY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE TRANSFER; HUMAN; METABOLISM; PHYSIOLOGY;

ANNEXIN A5; ANTIGENS, CD95; APOPTOSIS; CASPASES; DNA FRAGMENTATION; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; HUMANS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; PROTEINS; RECEPTORS, CELL SURFACE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032222873     PISSN: 14623935     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Ambrosini G, Adida C, Altieri C (1997) A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nature Med 3: 917-21
2. Baker SJ, Markowitz S, Fearn ER, Willson JKV, Vogelstein B (1990) Suppression of human colorecatal carcinoma cell growth by wild type p53. Science 249: 912-14
3. Cai Q, Huang X-L, Rappocciolo G, Rinaldo CR (1990) Natural killer cell responses in homosexual males with early HIV infection. J Acquir Immune Defic Syndr 3: 669-76
4. Chen Y, Smith MR, Thirumalai K, Zychilinsky A (1996) A bacterial invasin induces macrophage apoptosis by binding directly to ICE. EMBO 15: 3853-60
5. Chinery R, Brockman JA, Peeler MO, Shyr Yu, Beauchamp RD, Coffey RJ (1997) Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53 independent induction of p21WAFl/CIPl via C/EBPß Nature Med 3: 1233-41
6. Cohen JJ, Duke RC ( 1992) Apoptosis and programmed cell death in immunity. Ann Rev Immunol 10: 267-93
7. Cotton MF, Ikle DN, Rapaport EL et al. (1997) Apoptosis of CD4+ and CD8+ T cells isolated immediately ex vivo correlates with disease severity in human immunodeficiency virus type 1 infection. Pediatr Res 42: 656-14
8. Darzynkiewicz Z, Juan G, Li X, Gorczyka W, Murakami T, Traganos F (1997) Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry 27: 1-20
9. Dive C, Gregory CD, Phipps DJ, Evans DL, Miller AE, Wyllie AH (1992) Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry. Biochim Biophys Acta 1133: 275-85
10. Dorigo O, Turla ST, Lebedeva S, Gjerset RA (1998) Sensitisation of rat glioblastoma multiforme to cisplatin in vivo following restoration of wild type p53 function. J Neurosurg 88: 535-40
11. Duke RC, Cohen JJ (1992) Morphological and biochemical assays of apoptosis. Curr Protocols Immunol (Suppl) 3: 3.17.1-16
12. Ellis PA, Smith IE, McCarthy 1C, Detre S, Salter J, Dowset M (1997) Preoperative chemotherapy induces apoptosis in early breast cancer. Lancet 349: 849
13. Gavrieli Y, ShermanY, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 119: 493-501
14. Glucksmann A (1951) Cell deaths in normal vertebrate ontogeny. Biol Rev 26: 59-86
15. Gorczyca W, Bruno S, Darzynkiewicz RJ, Gong J, Darzynkiewicz Z (1992) DNA strand breaks occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. Int J Oncol 1:639-8
16. Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994) Mutation in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-78
17. Guichon A, Zychlinsky A (1996) Apoptosis as a trigger of inflammation in shigella induced cell death. Biochem Soc Trans 24: 1051-4
18. Gura T (1997) How TRAIL kills cancer cells, but not normal cells. Science 111: 768
19. Kaghad M, Bonnet H, Yang A et al. (1997) Monoallelically expressed gene related to p53 at Ip36, a region frequently deleted in neutoblastoma and other human cancers. Cell 90: 809-19
20. Katsikis PD, Wunderlich ES, Smith CA, Herzenberg LA, Herzenberg LA (1995) Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 181: 2029-36
21. Kerr JRR, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Er J Cancer 26: 239-57
22. Leithauser F, Dhein J, Mechtersheimer G et al. (1993) Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumour necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Investig 69: 415-29
23. Nicholson DW, Thornberry NA (1997) Caspases: killer proteases. TIBS 22: 299-306
24. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunolog Methods 139: 271-9
25. O'Brien MC, Healy SF, Raney SR et al. (1997) Discrimination of late apoptotic/necrotic cells (type III) by flow cytometry in solid tumours. Cytometry 28: 81-9
26. Pötten CS (1996) What is an apoptotic idex measuring? A commentary. Br J Cancer 74: 1743-8
27. Salzman GC, Singham SB, Johnston RG, Bohren CF (1990) Light scattering and cytometry. In: Melamed MR, Lindmo T, Mendelsohn ML, eds. Flow Cytometry and Sorting. Wiley-Liss, New York: 81-107
28. Swat W, Ignatowicz L, Kisielow P ( 1991 ) Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry. J Immunolog Methods 137: 779-87
29. Swenson KM, Ke B, Wang T et al. (1998) Fas ligand gene transfer to renal allografts in rats. Transplantation 65: 155-60
30. van Engeland M, Nieland LJW, Ramaekers PCS, Schutte B, Reutelingsberger CPM (1998) Annexin-V affinity assay: a review on an apoptosis detection system based on phospatidylserine exposure. Cytometry 31: 1-9
31. Webb A, Cunningham D, Cotter F et al. (1997) Bcl-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 349: 1137-41
32. Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-6
33. Wyllie AH, Kerr JFR, Currie AR (1980) Cell death: the significance of apoptosis. Int Rev Cytology 68: 251-304
34. Yonemitsu Y, Kaneda Y, Nakashima Y et al. (1998) Transfer of wild type p53 gene effectively inhibits vascular smooth muscle proliferation in vitro and in vivo. Circ Res 82: 147-56