yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex

Molecular Cell

Volumn 2, Issue 5, 1998, Pages 683-692

  Natarajan, Krishnamurthy ^a   Jackson, Belinda M ^a   Rhee, Eugene ^a   Hinnebusch, Alan G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; AMITROLE; DNA BINDING PROTEIN; FUNGAL PROTEIN; HISTONE ACETYLTRANSFERASE; HYBRID PROTEIN; HYDROLYASE; IMIDAZOLEGLYCEROLPHOSPHATE DEHYDRATASE; PROTEIN KINASE; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE PROTEIN; TAF(II)61 PROTEIN, S CEREVISIAE; TATA BINDING PROTEIN ASSOCIATED FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR II; TRANSCRIPTION FACTOR IID;

ARTICLE; BIOLOGICAL MODEL; CELL DIVISION; DRUG EFFECT; FUNGAL GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NORTHERN BLOTTING; PHENOTYPE; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SERODIAGNOSIS;

ACETYLTRANSFERASES; AMITROLE; BLOTTING, NORTHERN; CELL DIVISION; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HISTONE ACETYLTRANSFERASES; HYDRO-LYASES; MODELS, GENETIC; MUTAGENESIS, INSERTIONAL; PHENOTYPE; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN KINASES; RECOMBINANT FUSION PROTEINS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII; TRANSCRIPTION, GENETIC;

EID: 0032214089     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80166-5     Document Type: Article

References (69)

1. Barberis, A., Pearlberg, J., Simkovich, N., Farrell, S., Reinagel, P., Bamdad, C., Sigal, G., and Ptashne, M. (1995). Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell 81, 359-368.
2. Barlev, N.A., Candau, R., Wang, L., Darpino, P., Silverman, N., and Berger, S.L. (1995). Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein. J. Biol. Chem. 270, 19337-19344.
3. Berger, S.L., Pina, B., Silverman, N., Marcus, G.A., Agapite, J., Regier, J.L., Triezenberg, S.J., and Guarente, L. (1992). Genetic isolation of ADA2: a potential transcription adaptor required for function of certain acidic domains. Cell 70, 251-265.
4. Brazas, R.M., and Stillman, D.J. (1993). Identification and purification of a protein that binds DNA cooperatively with the yeast SWI5 protein. Mol. Cell. Biol. 13, 5524-5537.
5. Brownell, J.E., Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, D.G., Roth, S.Y., and Allis, C.D. (1996). Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84, 843-851.
6. Burke, T.W., and Kadonaga, J.T. (1997). The downstream core promoter element, DPE, Is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. Genes Dev. 11, 3020-3031.
7. Burley, S.K., and Roeder, R.G. (1996). Biochemistry and structural biology of transcription factor IID (TFIID). Annu. Rev. Biochem. 65, 769-799.
8. Burns, N., Grimwade, B., Ross-Macdonald, P.B., Choi, E.Y., Finberg, K., Roeder, G.S., and Snyder, M. (1994). Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. Genes Dev. 8, 1087-1105.
9. Chatterjee, S., and Struhl, K. (1995). Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain. Nature 374, 820-822.
10. Chen, J.L., Attardi, L.D., Verrijzer, C.P., Yokomori, K., and Tjian, R. (1994). Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell 79, 93-105.
11. Choder, M. (1991). A general topoisomerase I-dependent transcriptional repression in the stationary phase in yeast. Genes Dev. 5, 2315-2326.
12. Drysdale, C.M., Duenas, E., Jackson, B.M., Reusser, U., Braus, G.H., and Hinnebusch, A.G. (1995). The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids. Mol. Cell. Biol. 15, 1220-1233.
13. Drysdale, C.M., Jackson, B.M., McVeigh, R., Klebanow, E.R., Bai, Y., Kokubo, T., Swanson, M., Nakatani, Y., Weil, P.A., and Hinnebusch, A.G. (1998). The Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex. Mol. Cell. Biol. 18, 1711-1724.
14. Eisenmann, D.M., Arndt, K.M., Ricupero, S.L., Rooney, J.W., and Winston, F. (1992). SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. Genes Dev. 6, 1319-1331.
15. Evans, C.F., Engelke, D.R., and Thiele, D.J. (1990). ACE1 transcription factor produced in Escherichia coli binds multiple regions within yeast metallothionein upstream activation sequences. Mol. Cell. Biol. 10, 426-429.
16. Farrell, S., Simkovich, N., Wu, Y., Barberis, A., and Ptashne, M. (1996). Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes Dev. 10, 2359-2367.
17. Gansheroff, L.J., Dollard, C., Tan, P., and Winston, F. (1995). The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo. Genetics 139, 523-536.
18. Gaudreau, L., Schmid, A., Blaschke, D., Ptashne, M., and Horz, W. (1997). RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter. Cell 89, 55-62.
19. Georgakopoulos, T., and Thireos, G. (1992). Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription. EMBO J. 11, 4145-4152.
20. Georgakopoulos, T., Gounalaki, N., and Thireos, G. (1995). Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2. Mol. Gen. Genet. 246, 723-728.
21. II110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc. Natl. Acad. Sci. USA 91, 192-196.
22. Grant, P.A., Duggan, L., Cote, J., Roberts, S.M., Brownell, J.E., Candau, R., Ohba, R., Owen-Hughes, T., Allis, C.D., Winston, F., et al. (1997). Yeast GcnS functions in two multisubunit complexes to acetylate nucleosomal histories: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11, 1640-1650.
23. Grant, P.A., Sterner, D.E., Duggan, L.J., Workman, J.L., and Berger, S.L. (1998a). The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell. Biol. 8, 193-197.
24. IIS are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94, 45-53.
25. Hinnebusch, A.G. (1986). The general control of amino acid biosynthetic genes in the yeast Saccharomyces cerevisiae. Crit. Rev. Biochem. 21, 277-317.
26. Hinnebusch, A.G. (1990). Transcriptional and translational regulation of gene expression in the general control of amino acid biosynthesis in Saccharomyces cerevisiae. Prog. Nucleic Acid Res. Mol. Biol. 38, 195-240.
27. Hinnebusch, A.G. (1992). General and pathway-specific regulatory mechanisms controlling the synthesis of amino acid biosynthetic enzymes in Saccharomyces cerevisiae. In The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, J. R. Broach, E.W. Jones and J.R. Pringle, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp. 319-414.
28. Hinnebusch, A.G., and Fink, G.R. (1983). Positive regulation in the general amino acid control of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 80, 5374-5378.
29. Hinnebusch, A.G., Lucchini, G., and Fink, G.R. (1985). A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene CYC1 of yeast. Proc. Natl. Acad. Sci. USA 82, 498-502.
30. Hoffmann, A., Chiang, C.M., Oelgeschlager, T., Xie, X., Burley, S.K., Nakatani, Y., and Roeder, R.G. (1996). Ahistone octamer-like structure within TFIID. Nature 380, 356-359.
31. Hope, I.A., and Struhl, K. (1986). Functional dissection of a eukaryotlc transcriptional activator protein, GCN4 of yeast. Cell 46, 885-894.
32. Horiuchi, J., Silverman, N., Marcus, G.A., and Guarente, L. (1995). ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex. Mol. Cell. Biol. 15, 1203-1209.
33. Horiuchi, J., Silverman, N., Pina, B., Marcus, G.A., and Guarente, L. (1997). ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADAS. Mol. Cell. Blol. 17, 3220-3228.
34. Jackson, B.M., Drysdale, C.M., Natarajan, K., and Hinnebusch, A.G. (1996). Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation. Mol. Cell. Biol. 16, 5557-5571.
35. II30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell 79, 107-117.
36. Jefferson, R.A. (1987). Assaying chimeric genes in plants: the GUS gene fusion system. Plant Mol. Biol. Rep. 5, 387-405.
37. Jiang, Y.W., and Stillman, D.J. (1992). Involvement of the SIN4 global transcritpional regulator in the chromatin structure of Saccharomyces cerevisiae. Mol. Cell. Biol. 12, 4503-4514.
38. Kim, Y.J., Bjorklund, S., Li, Y., Sayre, M.H., and Kornberg, R.D. (1994). A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77, 599-608.
39. Klages, N., and Strubin, M. (1995). Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo. Nature 374, 822-823.
40. Klein, C., and Struhl, K. (1994). Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo. Science 266, 280-282.
41. Kohrer, K., and Domdey, H. (1991). Preparation of high molecular weight RNA. In Methods in Enzymology: Guide to Yeast Genetics and Molecular Biology, C. Guthrie and G.R. Fink, eds. (San Diego: Academic Press, Inc.), pp. 398-405.
42. Koleske, A.J., and Young, R.A. (1994). An RNA polymerase II holoenzyme responsive to activators. Nature 368, 466-469.
43. Koleske, A.J., and Young, R.A. (1995). The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem. Sci. 20, 113-116.
44. Kuo, M.H., Zhou, J., Jambeck, P., Churchill, M.E.A., and Allis, C.D. (1998). Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev. 12, 627-639.
45. II31 protein is a transcriptional coactivator of the p53 protein. Proc. Natl. Acad. Sci. USA 92, 5154-5158.
46. Madison, J.M., and Winston, F. (1997). Evidence that Spt3 functionally interacts with Mot1, TFIIA, and TATA-binding protein to confer promoter-specific transcriptional control in Saccharomyces cerevisiae. Mol. Cell. Biol. 17, 287-295.
47. Marcus, G.A., Silverman, N., Berger, S.L., Horiuchi, J., and Guarente, L. (1994). Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. EMBO J. 13, 4807-4815.
48. Marcus, G.A., Horiuchi, J., Silverman, N., and Guarente, L. (1996). ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription. Mol. Cell. Biol. 16, 3197-3205.
49. Moehle, C.M., and Hinnebusch, A.G. (1991). Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 11, 2723-2735.
50. Moqtaderi, Z., Bai, Y., Poon, D., Well, P.A., and Struhl, K. (1996a). TBP-associated factors are not generally required for transcriptional activation in yeast. Nature 383, 188-191.
51. Moqtaderi, Z., Yale, J.D., Struhl, K., and Buratowski, S. (1996b). Yeast homologues of higher eukaryotic TFIID subunits. Proc. Natl. Acad. Sci. USA 93, 14654-14658.
52. IIS. Mol. Cell 1, 925-931.
53. Poon, D., Campbell, A.M., Bai, Y., and Weil, P.A. (1994). Yeast Taf170 is encoded by MOT1 and exists in a TATA box-binding protein (TBP)-TBP-associated factor complex distinct from transcription factor IID. J. Biol. Chem. 269, 23135-23140.
54. Ptashne, M., and Gann, A. (1997). Transcriptional activation by recruitment. Nature 386, 569-577.
55. Roberts, S.M., and Winston, F. (1997). Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and GcnS proteins, with the Snf/Swi and Srb/mediator complexes. Genetics 147, 451-465.
56. Saleh, A., Lang, V., Cook, R., and Brandi, J. (1997). Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2. J. Biol. Chem. 272, 5571-5578.
57. Sauer, F., Hansen, S.K., and Tjian, R. (1995a). DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Science 270, 1825-1828.
58. IIS directing synergistic activation of transcription. Science 270, 1783-1788.
59. IIS mediate activation of transcription in the Drosophila embryo. Cell 87, 1271-1284.
60. II145 functions as a core promoter selectivity factor, not a general coactivator. Cell 90, 615-624.
61. Song, W., Treich, I., Qian, N., Kuchin, S., and Carlson, M. (1996). SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II. Mol. Cell. Biol. 16, 115-120.
62. Takemaru, K., Harashima, S., Ueda, H., and Hirose, S. (1998). Yeast coactivator M BF1 mediates GCN4-dependent transcriptional activation. Mol. Cell. Biol. 18, 4971-4976.
63. II60. Science 267, 100-104.
64. Uesugi, M., Nyanguile, O., Lu, H., Levine, A.J., and Verdine, G.L. (1997). Induced α helix in the VP16 activation domain upon binding to a human TAF. Science 277, 1310-1313.
65. IIs. Nature 383, 185-188.
66. II145 required for transcription of G1/S cyclin genes and regulated by the cellular growth state. Cell 90, 607-614.
67. Wang, L., Liu, L., and Berger, S.L. (1998). Critical residues for histone acetylation by GcnS, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. Genes Dev. 12, 640-653.
68. Xiao, H., Friesen, J.D., and Lis, J.T. (1995). Recruiting TATA-binding protein to a promoter: transcriptional activation without an upstream activator. Mol. Cell. Biol. 15, 5757-5761.
69. Xie, X., Kokubo, T., Cohen, S.L., Mirza, U.A., Hoffmann, A., Chait, B.T., Roeder, R.G., Nakatani, Y., and Burley, S.K. (1996). Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature 380, 316-322.