Formation of liver microsomal MDA-protein adducts in mice with chronic dietary iron overload

Toxicology Letters

Volumn 98, Issue 1-2, 1998, Pages 31-39

  Valerio Jr , Luis G ^a   Petersen, Dennis R ^b  

^a Box C238 Sch Pharm Univ C   (United States)

^b Box C 238 Molec Environ T ^*  (United States)

Author keywords

Iron; Iron overload; Lipid peroxidation; Malondialdehyde; Mice; Oxidative stress

Indexed keywords

MALONALDEHYDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; FIBROGENESIS; IMMUNOPRECIPITATION; IRON OVERLOAD; LIPID PEROXIDATION; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; BLOTTING, WESTERN; CHRONIC DISEASE; IRON, DIETARY; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED DBA; MICROSOMES, LIVER; NONHEME IRON PROTEINS; PRECIPITIN TESTS; PROTEINS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032167889     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00100-3     Document Type: Article

References (40)

1. Bacon B.R., Britton R.S. The pathology of hepatic iron overload: A free radical-mediated process? Hepatology. 11:1990;127-137.
2. Bacon B.R., Tavill A.S., Brittenham G.M., Park C.H., Recknagel R.O. Hepatic lipid peroxidation in vivo in rats with chronic iron overload. J. Clin. Invest. 71:1983;429-439.
3. Bacon B.R., Brittenham G.M., Tavill A.S., McLaren C.E., Park C.H., Recknagel R.O. Hepatic lipid peroxidation in vivo in rats with chronic dietary iron overload is dependent on hepatic iron concentration. Trans. Assoc. Am. Phys. 96:1983;146-154.
4. Bacon B.R., Healey J.F., Brittenham G.M., Park C.H., Nunnari J., Tavill A.S., Bonkovsky H.L. Hepatic microsomal function in rats with chronic dietary iron overload. Gastroenterology. 90:1986;1844-1853.
5. Bassett M., Halliday J.W., Powell L.W. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology. 6:1986;24-29.
6. Britton R.S., Bacon B.R. Role of free radicals in liver diseases and hepatic fibrosis. Hepatogastroenterology. 41:1994;343-348.
7. Britton R.S. Metal-induced hepatotoxicity. Sem. Liver Dis. 16:1996;3-12.
8. Britton R.S., O'Neill R., Bacon B.R. Chronic dietary iron overload in rats results in impaired calcium sequestration by hepatic mitochondria and microsomes. Gastroenterology. 101:1991;806-811.
9. Deugnier Y.M., Loreal O., Turlin B.D., Guyader D., Jouanolle H., Moirand R., Jacquelinet C., Brissot P. Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations. Gastroenterology. 102:1992;2050-2059.
10. Draper H.H., Squires E.J., Mahmoodi H., Wu J., Agarwal S., Hadley M. A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials. Free Rad. Biol. Med. 15:1993;353-363.
11. Dresow B., Albert C., Zimmermann I., Nielsen P. Ethane exhalation and vitamin E/ubiquinol status as markers of lipid peroxidation in ferrocene iron-loaded rats. Hepatology. 21:1995;1099-1105.
12. Esterbauer H., Zollner H., Schaur R. Aldehydes formed by lipid peroxidation: mechanisms of formation, occurrence, and determination. Vigo-Pelfrey C. Membrane Lipid Peroxidation. 1990;239-269 CRC Press, Boca Raton, FL.
13. Esterbauer H., Schauer R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde, and related aldehydes. Free Rad. Biol. Med. 11:1991;81-128.
14. Falconer D.S. Introduction to Quantitative Genetics. 1960;312-329 The Ronald Press Company, New York.
15. Goddard J.G., Sweeney G.D. Ferric nitrilotriacetate: a potent stimulant of in vivo lipid peroxidation in mice. Biochem. Pharmacol. 32:1983;3879-3882.
16. Gornall A.G., Bardawill C.J., David M.M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177:1949;751-766.
17. Halliwell B., Gutteridge J.M.C. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 219:1984;1-14.
18. Hartley D.P., Kroll D.J., Petersen D.R. Prooxidant-initiated lipid peroxidation in isolated rat hepatocytes: detection of 4-hydroxynonenal- and malondialdehyde-protein adducts. Chem. Res. Tox. 10:1997;895-905.
19. Houglum K., Filip M., Witztum J.L., Chojkier M. Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload. J. Clin. Invest. 86:1991;1991-1998.
20. Jamall I.S., Finelli V.N., Que-Hee S.S. A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Anal. Biochem. 112:1981;70-75.
21. Kappus H. Lipid peroxidation: mechanism and biological relevance. Aruoma O.I. Free Radicals and Food Additives. 1991;Taylor and Francis, London, England.
22. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
23. Little R., Petersen D.R. Subcellular distribution and kinetic parameters of hs mouse liver aldehyde dehydrogenase. Comp. Biochem. Physiol. C: Comp. Pharm. Tox. 74C:1983;271-279.
24. Nielsen P., Heinrich H.C. Metabolism of iron from (3,5,5-trimethylhexanoyl)ferrocene in rats: A dietary model for severe iron overload. Biochem. Pharm. 45:1993;385-391.
25. Palinski W., Roenfeld M.E., Yla-Herttuala S., Gurtner G.C., Socher S.S., Butler S.W., Parthasarathy S., Carew T.E., Steinberg D., Witztum J.L. Low density lipoprotein undergoes oxidative modification in vivo. Proc. Natl. Acad. Sci. USA. 86:1989;1372-1376.
26. Parkkila S., Niemela O., Britton R.S., Brown K.E., Yla-Herttuala S., O'Neill R., Bacon B.R. Vitamin E decreases hepatic levels of aldehyde-derived peroxidation products in rats with iron overload. Am. J. Phys. 270:1996;G376-G384.
27. Pietrangelo A., Rocchi E., Schiaffonati L., Ventura E., Cairo G. Liver gene expression during chronic dietary iron overload in rats. Hepatology. 11:1990;798-803.
28. Pietrangelo A., Borella F., Casalgrandi G. Antioxidant activity of silybin in vivo during long-term iron overload in rats. Gastroenterology. 101:1995;806-811.
29. Pietrangelo A., Gualdi R., Casalgrandi G., Montosi G., Ventura E. Molecular and cellular aspects of iron-induced hepatic cirrhosis in rodents. J. Clin. Invest. 95:1995;1824-1831.
30. Pietrangelo A. Metals, oxidative stress, and hepatic fibrogenesis. Sem. Liver Dis. 16:1996;13-30.
31. Ruwart M.J., Wilkinson K.F., Rush B.D., Vidmar T.J., Peters K.M., Henley K.S., Appelman H.D., Kim K.Y., Schuppan D.S., Hahn E.G. The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. Hepatology. 10:1989;801-806.
32. Stadtman E.R. Protein oxidation and aging. Science. 257:1992;1220-1224.
33. Stal P., Hultcrantz R. Iron increases ethanol toxicity in rat liver. J. Hepatology. 17:1993;108-115.
34. Stohs S.J., Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Rad. Biol. Med. 18:1995;321-336.
35. Tavill A.S., Sharma B.K., Bacon B.R. Iron and the liver: genetic hemochromatosis and other hepatic iron overload disorders. Prog. Liver Dis. 9:1990;281-305.
36. Torrance J.D., Bothwell T.H. Tissue iron stores. Cook J.D. Iron. 1980;90-115 Churchill Livingstone, New York.
37. Tsukamoto H., Horne W., Kaminmura S., Niemela O., Yla-Herttuala S. Experimental liver cirrhosis induced by alcohol and iron. J. Clin. Invest. 96:1995;620-630.
38. Valerio L.G. Jr, Parks T., Petersen D.R. Alcohol mediates increases in hepatic and serum nonheme iron in a rodent model for alcohol-induced liver injury. Alcohol Clin. Exp. Res. 20:1996;1352-1361.
39. Weintraub L.R., Goral A., Grasso J., Franzblau C., Sullivan A., Sullivan S. Pathogenesis of hepatic fibrosis in experimental iron overload. Brit. J. Haematol. 59:1985;321-331.
40. Wu H.-H., Meydani M., Meydani S.N., Blumberg J.B., White K., Munro H.N. Effect of dietary iron-overload in young and old rats on lipid peroxidation, prostaglandin synthesis and lymphocyte proliferation. J. Nutr. 120:1987;280-289.