Chromatin structure and cardiac gene expression

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 9, 1998, Pages 1673-1681

  Huang, Weei Yuarn ^a   Liew, Choong Chin ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cardiac hypertrophy; Chromatin remodelling factors; DNase I hypersensitive sites; Transcription factors

Indexed keywords

HISTONE ACETYLTRANSFERASE; MYOSIN HEAVY CHAIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR;

CHROMATIN STRUCTURE; GENE ACTIVATION; GENE EXPRESSION; HEART DEVELOPMENT; PRIORITY JOURNAL; REVIEW;

EUKARYOTA;

EID: 0032167435     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0738     Document Type: Review

References (82)

1. ALMER A, HORZ W, 1986. Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast. EMBO J 5: 2681-2687.
2. ARCHER TK, LEFEBVRE P, WOLFORD RG, HAGER GL, 1992. Transcription factor loading on the MMTV promoter: A bimodal mechanism for promoter activation. Science 255: 1573-1576.
3. ARMSTRONG JA, EMERSON BM, 1996. NF-E2 disrupts chromatin structure at human β-globin locus control region hypersensitive site 2 in vitro. Mol Cell Biol 16: 5634-5644.
4. BANNISTER A, KOUZARIDES T, 1996. The CBP co-activator is a histone acetyltransferase. Nature 384: 641-643.
5. BECKER PB, 1994. The establishment of active promoters in chromatin. BioEssays 16: 541-547.
6. BIBEN C, KIRSCHBAUM BJ, GARNER I, BUCKINGHAMM, 1994. Novel muscle-specific enhance sequences upstream of the cardiac actin gene. Mol Cell Biol 14: 3504-3513.
7. BOHELER KR, CHASSAGNE C, MARTIN X, WISNEWSKY C, SCHWARTZ K, 1992. Cardiac expression of α-and β-myosin heavy chains and sarcomeric α-actins are regulated through transcriptional mechanisms. J Biol Chem 267: 12979-12985.
8. BREHM A, MISKA EA, MCCANCE DJ, REID JL, BANNISTER AJ, KOUZARIDES T, 1998. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391: 597-601.
9. BROWNELL JE, ZHOU J, RANALLI T, KOBAYASHI R, EDMONDSON DG, ROTH SY, ALLIS CD, 1996 Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 83: 843-851.
10. CAIRNS BR, LORCH Y, LI Y, ZHANG M, LACOMIS L, ERDJUMENT-BROMAGE H, TEMPST P, DU J, LAURENT B, KORENBERG RD, 1996a. RSC, an essential, abundant chromatin-remodelling complex. Cell 87: 1249-1260.
11. CAIRNS BR, LEVINSON RS, YAMAMOTO KR, KORNBERG RD, 1996b. Essential role of Swp73p in the function of yeast Swi/Snf complex. Gene Dev 10: 2131-2144.
12. CHEN Z, FRIEDRICH GA, SORIANO P, 1994. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev 8: 2293-2301.
13. CHIEN KR, KNOWLTON KU, ZHU H, CHIEN S, 1991. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 5: 3037-3046.
14. ELGIN SCR, 1988. The formation and function of DNase I hypersensitive sites in the process of gene activation. J Biol Chem 263: 19259-19262.
15. EPP TA, DIXON IC, WANG H-Y, SOLE MJ, LIEW C-C, 1993. Structural organization of the human cardiac α-MyHC gene. Genomic 18: 505-509.
16. FASCHER KD, SCHMITZ J, HORZ W, 1990. Role of transacting proteins in the generation of active chromatin at the PHO5 promoter in S. Cerevisiae. EMBO J. 9: 2523-2528.
17. FELSENFELD G, 1992. Chromatin as an essential part of the transcriptional mechanism. Nature 355: 219-224.
18. FIRULLI AB, MCFADDEN DG, LIN Q, SRIVASTAVA D, OLSON E, 1998. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor HANDI. Nat Genet 18: 266-270.
19. FLINK IL, MORKIN E, 1990. Interaction of thyroid hormone receptors with strong and weak cis-acting elements in the human α-myosin heavy chain promoter. J Biol Chem 265: 11233-11237.
20. FLINK IL, MORKIN E, 1995. Alternatively processed isoforms of cellular nucleic acid-binding protein interact with a suppressor region of the human β-myosin heavy chain gene. J Biol Chem 270: 6959-6965.
21. FLINK IL, EDWARDS JG, BAHL JJ, LIEW C-C, SOLE MJ, MORKIN E, 1992. Characterization of a strong positive cis-acting element of the β-myosin heavy chain gene in fetal rat heart cells. J Biol Chem 267: 9917-9924.
22. GREPIN C, DAGNINO L, ROBITAILLE L, HABERSTROH L, ANTAKLY T, NEMER M, 1994. A hormone-encoding gene identifies a pathways for cardiac but not skeletal muscle gene transcription. Mol Cell Biol 14: 3115-3129.
23. GROSS DS, GARRARD WT, 1988. Nuclease hypersensitive sites in chromatin. Annu Rev Biochem 57: 159-197.
24. HASEGAWA K, LEE SJ, JOBE SM, MARKHAM BE, KITSIS RN, 1997. Cis-acting sequences that mediate induction of the β-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction. Circulation 96: 3943-3953.
25. HAYES JJ, WOLFFE AP, 1992. Histones H2A/H2B inhibit the interactions of transcription factor IIIA with the Xenopus borealis somatic 5S RNA gene in a nucleosome. Proc Natl Acad Sci 89: 1229-1233.
26. HEINZEL T, LAVINSKY RM, MULLEN T-M, SODERSTROM M, LAHERTY CD, TORCHIA J, YANG W-M, BRARD G, NGO SD, DAVIE JR, SETO E, EISENMAN RN, ROSE DW, GLASS CK, ROSENFELD MG, 1997. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387: 43-48.
27. HOEY T, SUN Y-L, WILLIAMSON K, XU X, 1995. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2: 461-472.
28. HUANG W-Y, LIEW C-C, 1997. A conserved GATA motif in a tissue-specific DNase I hypersenstive site of the cardiac α-myosin heavy chain gene. Biochem J 325: 47-51.
29. HUANG W-Y, LIEW C-C, 1998. Chromatin remodelling of the cardiac β-MyHC gene. Biochem J 330: 871-876.
30. HUANG W-Y, CHEN J-J, SHIH N-L, LIEW CC, 1997. Multiple muscle-specific regulatory elements are associated with a DNase I hypersensitive sites of the cardiac β-myosin heavy chain gene. Biochem J 327: 507-512.
31. IZUMO S, LOMPRE A-M, MATSUOKA R, KOREN G, SCHWARTZ K, NADAL-GINARD B, MAHDAVI V, 1987. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. J Clin Invest 79: 970-977.
32. KARIYA K, FARRANCE IKG, SIMPSON PC, 1993. Transcriptional enhancer factor-1 in cardiac myocytes interacts with an alpha 1 adrenergic-and a beta-protein kinase C-inducible element in the rat beta-myosin heavy chain promoter. J Biol Chem 268: 26658-26662.
33. KNOTTS S, RINDT H, NEUMANN J, ROBBINS J, 1994. In vivo regulation of the mouse β-myosin heavy chain gene. J Biol Chem 269: 31275-31282.
34. KUO CT, MORRISEY EE, ANANDAPPA R, SIGRIST K, LU MM, PARMACEK MS, SOUDAIS C, LEIDEN JM, 1997. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev 11: 1048-1060.
35. LEWIN B, 1994. Chromatin and gene expression: constant questions, but changing answers. Cell 79: 397-406.
36. LIEW C-C, SOLE M-J, YAMAUCHI-TAKIHARA K, KELLAM B, ANDERSON DH, LIN L, LIEW JC, 1990. Complete sequence and organization of the human cardiac β-myosin heavy chain gene. Nucleic Acids Res 18: 3647-3651.
37. LIN Q, SCHWARZ J, BUCANA C, OLSON EN, 1997. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276: 1404-1407.
38. LOMPRE AM, NADAL-GINARD B, MAHDAVI V, 1984. Expression of the cardiac ventricular alpha and beta-myosin heavy chain genes is developmentally and hormonally regulated. J Biol Chem 259: 6437-6446.
39. LUGER K, MADER AW, RICHMOND RK, SARGENT DF, RICHMOND TJ, 1997. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260.
40. LUO RX, POSTIGO AA, DEAN D, 1998. RB interacts with histone deacetylase to repress transcription. Cell 92: 463-473.
41. LYONS I, PARSONS LM, HARTLEY L, LI R, ANDREWS JE, ROBB L, HARVEY RP, 1995. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeobox gene Nkx2-5. Gene Dev 9: 1654-1666.
42. MABLY JD, LIEW CC, 1996. Factors involved in cardiogenesis and the regulation of cardiac-specific gene expression. Circ Res 79: 4-13.
43. MAGNAGHI-JAULIN L, GROISMAN R, NAGUIBNEVA I, ROBIN P, LORAIN S, LEVILLAN JP, TROALEN F, TROUCHE D, HAREL-BELLAN A, 1998. Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391: 601-605.
44. MCPHERSON CE, SHIM E-Y, FRIEDMAN DS, ZARET KS, 1993. An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array. Cell 75: 387-398.
45. II250 sub unit of TFIID has histone acetyltransferase activity. Cell 87: 1261-1270.
46. MOLKENTIN JD, MARKHAM BE, 1993. Myocyte-specific enhancer-binding factor (MEF-2) regulates α-cardiac myosin heavy chain gene expression in vitro and in vivo. J Biol Chem 268: 19510-19512.
47. MOLKENTIN JD, MARKHAM BE, 1994. An M-CAT binding factor and an RSRF-related A-rich binding factor positively regulate expression of the α-cardiac myosin heavy-chain gene in vivo. Mol Cell Biol 14: 5065-5065.
48. MOLKENTIN JD, BROGAN RS, JOBE SM, MARKHAM BE, 1993. Expression of the α-myosin heavy chain gene in the heart is regulated in part by an E-box dependent mechanism. J Biol Chem 268: 2602-2609.
49. MOLKENTIN JD, KALVAKOLANU DV, MARKHAM BE, 1994. Transcription factor GATA-4 regulates cardiac muscle-specific expression of the α-myosin heavy-chain gene. Mol Cell Biol 14: 4947-4957.
50. MOLKENTIN JD, LIN Q, DUNCAN SA, OLSON EN, 1997. Reqirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev 11: 1061-1072.
51. MOLKENTIN JD, LU J-R, ANTOS CL, MARKHAM B, RICHARDSON J, ROBBINS J, GRANT SR, OLSON E, 1988. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93: 215-228.
52. MORKIN E, 1993. Regulation of myosin heavy chain genes in the heart. Circulation 87: 1451-14661.
53. MUCHARDT C, YANIV M, 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm gene potentiate transcriptional activation by the glucocorticoid receptor. EMBO J 12: 4279-4290.
54. OGRYZKO VV, SCHILTZ RL, RUSSANOVA V, HOWARD BH, NAKATANI Y, 1996. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87: 953-959.
55. ORPHANIDES G, LAGRANGE T, REINBERG D, 1996. The general transcription factors of RNA polymerase II. Genes Dev 10: 2657-2683.
56. PETERSON CL, 1996. Multiple SWItches to turn on chromatin. Curr Opin. Genet Dev 6: 171-175.
57. PETERSON CL, TAMKUN JW, 1995. The SWI/SNF complex: a chromatin remodelling machine? Trends Biochem Sci 20: 143-146.
58. RICHARD-FOY H, HAGER GL, 1987. Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter. EMBO J 6: 2321-2328.
59. SCHMID A, FASCHER K-D, HORZ W, 1992. Nucleosome disruption at the yeast PHO5 promoter upon PHO5 induction occurs in the absence of DNA replication. Cell 71: 853-864.
60. SIMPSON RT, 1986. Nucleosome positioning in vivo and in vitro. BioEssays 4: 172-176.
61. STRUHL K, 1998. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 12: 599-606.
62. SRIVASTAVA D, THOMAS T, LIN Q, KIRBY ML, BROWN D, OLSON E, 1997. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet 16: 154-160.
63. SUBRAMANIAN A, GULICK J, NEUMANN J, KNOTTS S, ROBBINS J, 1993. Transgenic analysis of the thyroid-responsive elements in the α-cardiac myosin heavy chain gene promoter. J Biol Chem 268: 4331-4336.
64. SVAREN J, HORZ W, 1996. Regulation of gene expression by nucleosomes. Curr Opin Genet Dev 6: 164-170.
65. TAYLOR ICA, WORKMAN JL, SCHUETZ TJ, KINGSTON RE, 1991. Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains. Genes Dev 5: 1285-1298.
66. THOMPSON CM, YOUNG RA, 1995. General requirement for RNA polymerase II holoenzymes in vivo. Proc Natl Acad Sci USA 92: 4587-4590.
67. THOMPSON WR, NADAL-GINARD B, MAHDAVI VA, 1991. MyoD1-independent muscle-specific enhancer controls the expression of the β-myosin heavy chain gene in skeletal and cardiac muscle cells. J Biol Chem 266: 22678-22688.
68. TRAVERS AA, 1987. DNA bending and nucleosome positioning. Trends Biochem Sci 12: 108-112.
69. TRUSS M, BARTSCH J, SCHELBERT A, HACHE JG, BEATO M, 1995. Hormone induce binding of receptors and transcription factors to a rearranged nucleosome on the MMTV ptomoter in vivo. EMBO J 14: 1737-1751.
70. TSUKIYAMA T, WU C, 1995. Purification and properties of an ATP-dependent nucleosome remodelling factor. Cell 83: 1011-1020.
71. WALLRATH LL, LU Q, GRANOK H, ELGIN SCR, 1994. Architectural variations of inducible eukaryotic promoters: preset and remodelling chromatin structures. BioEssays 16: 165-170.
72. WANG W, XUE Y, ZHOU S, KUO A, CAIRNS BR, CRABTREE GR, 199 6a. Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev 10: 2117-2130.
73. WANG W, COTE J, XUE Y, ZHOU S, KHAVARI PA, BIGGAR SR, MUCHARDT C, KALPANA GV, GOFF SP, YANIV M, WORKMAN JL, CRABTREE GR, 1996b. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J 15: 5370-5382.
74. 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes. J Clin Invest 85: 1206-1214.
75. WILSON CJ, CHAO DM, IMBALZANO AN, SCHNITZLER GR, KINGSTON RE, YOUNG RA, 1996. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodelling. Cell 84: 235-244.
76. WINSTON F, CARLSON M, 1992. Yeast SWI/SNF: transcriptional activators and the SPT/SIN chromatin connection. Trends Genet 8: 387-391.
77. WINTER BB, ARNOLD HH, 1987. Tissue-specific DNase I-hypersensitive sites and hypomethylation in the chicken cardiac myosin light chain gene (L2-A) J Biol Chem 262: 13750-13757.
78. WOLFFE AP, 1997. Transcriptional control: Sinful repression. Nature 387: 16-17.
79. WOLFFE AP, PRUSS D, 1996. Targeting chromatin disruption: transcription regulators that acetylate histones. Cell 84: 817-819.
80. YANG W-M, YAO Y-L, SUN J-M, DAVIE JR, SETO E, 1997. Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J Biol Chem 272: 28001-28007.
81. YANG XJ, OGRYZKO VV, NISHIKAWA J, HOWARD BH, NAKATANI Y, 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382: 319-324.
82. ZELLER R, BLOCK KD, WILLIAMS BS, ARCECI RJ, SEIDMAN CE, 1987. Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis. Genes Dev 1: 693-698.