Virus-Specific Memory Effector T Lymphocytes Exhibit Different Cytokine Responses to Antigens during Experimental Murine Respiratory Syncytial Virus Infection

Journal of Virology

Volumn 71, Issue 1, 1997, Pages 678-685

  Srikiatkhachorn, Anon ^a   Braciale, Thomas J ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; VIRUS FUSION PROTEIN; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EFFECTOR CELL; EXPERIMENTAL INFECTION; FEMALE; HISTOPATHOLOGY; LOEFFLER PNEUMONIA; LYMPHOCYTE DIFFERENTIATION; MEMORY CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SENSITIZATION; T LYMPHOCYTE SUBPOPULATION; VACCINIA VIRUS; VIRUS RECOMBINANT;

ANIMALS; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; EOSINOPHILS; FEMALE; HN PROTEIN; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; LUNG; MALE; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; T-LYMPHOCYTES; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS;

EID: 0031060290     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.1.678-685.1997     Document Type: Article

References (40)

1. Alwan, W. H., W. J. Kozlowska, and P. J. M. Openshaw. 1994. Distinct types of lung diseases caused by functional subset of antiviral T cells. J. Exp. Med. 179:81-89.
2. Alwan, W. H., F. M. Record, and P. J. M. Openshaw. 1993. Phenotypic and functional characterization of T cell lines specific to individual respiratory syncytial virus proteins. J. Immunol. 150:5211-5218.
3. Alwan, W. H., and P. J. M. Openshaw. 1993. Distinct patterns of T- and B-cell immunity to respiratory syncytial virus induced by individual viral proteins. Vaccine 11:431-437.
4. Anderson, L. J., C. Tsou, C. Potter, H. L. Keyserling, T. F. Smith, G. Ananaba, and C. R. Bangham. 1994. Cytokine response to respiratory syncytial virus stimulation of human peripheral blood mononuclear cells. J. Infect. Dis. 170:1201-1208.
5. Ball, L. A., K. K. Y. Young, K. Anderson, P. L. Collins, and G. W. Wertz. 1986. Expression of the major glycoprotein G of human respiratory syncytial virus from recombinant vaccinia virus vectors. Proc. Natl. Acad. Sci. USA 83:246-250.
6. Baumgarth, N., L. Brown, D. Jackson, and A. Kelso. 1994. Novel features of respiratory tract T-cell response to influenza virus infection: lung T cells increase expression of gamma Interferon mRNA in vivo and maintain high levels of mRNA expression for interleukin-5 (IL-5) and IL-10. J. Virol. 68:7575-7581.
7. Baumgarth, N., and A. Kelso. 1996. In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue. J. Virol. 70:4411-4418.
8. Belosevic, M., D. S. Finbloom, P. H. Van Der Meide, M. V. Slayter, and C. A. Nacy. 1989. Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143:226-274.
9. Bradley, L. M., G. G. Atkins, and S. L. Swain. 1992. Long-term memory CD4+ Tcells from the spleen lack Mel-14, the lymph node homing receptor. J. Immunol. 148:324.
10. Bradley, L. M., D. D. Duncan, K. Yoshimoto, and S. L. Swain. 1993. Memory effectors: a potent IL-4 secreting helper T cells population that develops in vivo after restimulation with antigen. J. Immunol. 150:3119-3130.
11. Chin, J., R. L. Magoffin, L. A. Shearer, J. H. Schieble, and E. H. Lennette. 1969. Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population. Am. J. Epidemiol. 89:449-463.
12. Coates, H. V., D. W. Alling, and R. M. Chanock. 1996. An antigenic analysis of respiratory syncytial virus isolates by a plaque reduction neutralization test. Am. J. Epidemiol. 83:299-313.
13. Conners, M., N. A. Giese, A. B. Kulkarni, C. Y. Firestone, H. C. Morse III, and B. R. Murphy. 1994. Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10. J. Virol. 68:5321-5325.
14. + T cells. J. Virol. 66:7444-7451.
15. Dalton, D., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739-1742.
16. Del Pretes, G. F., M. de Carli, C. Mastromauro, R. Biagiotti, D. Macchia, P. Falagiani, M. Ricci, and S. Romagnani. 1991. Purified protein derivative of Mycobacterium tuberculosis and excreting - secreting - antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profiles of cytokine production. J. Clin. Invest. 88:346-350.
17. Doherty, P. C., W. Allen, and M. Eichelberger. 1992. Roles of αβ and γδ T cell subsets in viral immunity. Annu. Rev. Immunol. 10:123-151.
18. Ehlers, S., and K. A. Smith. 1991. Differentiation of T cell lymphokine gene expression. The in vitro acquisition of T cell memory. J. Exp. Med. 173:25-36.
19. Gajewski, T. F., J. Joyce, and F. W. Fitch. 1989. Antiproliferative effect of IFN-gamma in immunoregulation. III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma. J. Immunol. 143:15-22.
20. Graham, B. S., M. D. Perkins, P. F. Wright, and D. T. Karzon. 1988. Primary respiratory syncytial virus infection in mice. J. Med. Virol. 26:153-162.
21. Graham, B. S., L. A. Bunton, P. F. Wright, and D. T. Karzon. 1991. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice. J. Clin. Invest. 88:1026-1033.
22. + T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J. Exp. Med. 180:1273-1282.
23. Heilman, C. A. 1990. Respiratory syncytial and parainfluenza viruses, J. Infect. Dis. 161:402-406.
24. + T cells. J. Exp. Med. 177:573-576.
25. Kim, H. W., J. G. Canchola, C. D. Brandt, G. Pyles, R. M. Chanock, K. E. Jensen, and R. H. Parrott. 1969. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine. Am. J. Epidemiol. 89:422-434.
26. Lukacher, A. E., V. L. Braciale, and T. J. Braciale. 1984 In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 160:814-826.
27. Mahanty, S., C. L. King, V. Kumaraswami, J. Reganatham, A. Maya, K. Jayaraman, J. S. Abrahms, E. A. Ottesen, and T. B. Nutman. 1993. IL-4 and IL-5 secreting lymphocyte population are preferentially stimulated by parasite-derived antigens in human tissue invasive nematodes infections. J. Immunol. 151:3704-3711.
28. Mo, X. Y., S. R. Sarawar, and P. C. Doherty. 1995. Induction of cytokines in mice with parainfluenza pneumonia. J. Virol. 69:1288-1291.
29. Mossman, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokines activities and secreted proteins. J. Immunol. 136:2348-2357.
30. Mossman, T. R., and R. I. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. 7:145-173.
31. Openshaw, P. J., S. L. Clarke, and F. M. Record. 1992. Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G. Int. Immunol. 4:493-500.
32. Pollard, A. M., and M. F. Lipscomb. 1990. Characterization of murine lung dendritic cells: similarities to Langerhans cells and thymic dendritic cells. J. Exp. Med. 172:159-167.
33. Sarawar, S. R., M. Sangster, R. L. Coffman, and P. C. Doherty. 1994. Administration of anti-IFN-γ antibody to β2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype. J. Immunol. 153:1246-1253.
34. Scott, P. 1991. IFN-γ modulates early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147:3149-3155.
35. Seder, R. A., and W. E. Paul. 1994. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu. Rev. Immunol. 12:635-673.
36. Singer, G. G., and A. K. Abbas. 1994. The Fas antigen is involved In peripheral but not thymic deletion of T lymphocyte in T cell receptor transgenic mice. Immunity 1:365-371.
37. Stott, E. J., G. Taylor, L. A. Ball, K. Anderson, K. K. Y. Young, A. M. Q. King, and G. W. Wertz. 1987. Immune and histopathological response in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus. J. Virol. 61:3855-3861.
38. Tang, Y. W., and B. S. Graham. 1994. Anti IL-4 treatment at immunization modulates cytokine expression, reduces illness and increases cytotoxic T lymphocyte activity in mice challenged with respiratory syncytial virus. J. Clin. Invest. 94:1953-1958.
39. Webb, S. R., J. Hutchinson, K. Hayden, and J. Sprent. 1994. Expansion, deletion of mature T cells exposed to endogenous superantigen in vivo. J. Immunol. 152:586-597.
40. Wertz, G. W., E. J. Stott, K. K. Y. Young, K. Anderson, and L. A. Ball. 1987. Expression of the fusion protein of human respiratory syncytial virus from recombinant vaccinia virus vectors and protection of vaccinated mice. J. Virol. 61:293-301.