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Volumn 255, Issue 3, 1998, Pages 727-733

Two metal-binding sites in a lead ribozyme bound to competitively by Pb2+ and Mg2+. Induced, structural changes as revealed by NMR

Author keywords

Lead ribozyme; Metal ion; NMR; RNA; Structure

Indexed keywords

LEAD; MAGNESIUM; RIBOZYME;

EID: 0032145446     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2550727.x     Document Type: Article
Times cited : (10)

References (33)
  • 1
    • 0026669321 scopus 로고
    • A small metalloribozyme with a two step mechanism
    • Pan, T. & Uhlenbeck, O. C. (1992) A small metalloribozyme with a two step mechanism. Nature 358, 560-563.
    • (1992) Nature , vol.358 , pp. 560-563
    • Pan, T.1    Uhlenbeck, O.C.2
  • 4
    • 0030576946 scopus 로고    scopus 로고
    • Site-specific cleavage reaction catalyzed by leadzyme is enhanced by combined effect of lead and rare earth ions
    • Sugimoto, N. & Ohmichi, T. (1996) Site-specific cleavage reaction catalyzed by leadzyme is enhanced by combined effect of lead and rare earth ions. FEBS Lett. 393, 97-100.
    • (1996) FEBS Lett. , vol.393 , pp. 97-100
    • Sugimoto, N.1    Ohmichi, T.2
  • 5
    • 0030610237 scopus 로고    scopus 로고
    • 2+ on the RNA cleavage reaction by a small ribozyme
    • 2+ on the RNA cleavage reaction by a small ribozyme, Biochemistry 36, 3514-3521.
    • (1997) Biochemistry , vol.36 , pp. 3514-3521
    • Ohmichi, T.1    Sugimoto, N.2
  • 8
    • 0030934345 scopus 로고    scopus 로고
    • Effect of structure modifications on the activity of the leadzyme
    • Chartrand, P., Usman, N. & Cedergren, R. (1997) Effect of structure modifications on the activity of the leadzyme, Biochemistry 36, 3145-3150.
    • (1997) Biochemistry , vol.36 , pp. 3145-3150
    • Chartrand, P.1    Usman, N.2    Cedergren, R.3
  • 10
    • 0028310908 scopus 로고
    • 31P chemical shift as a probe of structural motifs in RNA
    • 31P chemical shift as a probe of structural motifs in RNA, J. Magn. Res. Ser. B 103, 82-86.
    • (1994) J. Magn. Res. Ser. B , vol.103 , pp. 82-86
    • Legault, P.1    Pardi, A.2
  • 12
    • 0028985763 scopus 로고
    • 2+P J coupling constants in isotropically labeled RNA
    • 2+P J coupling constants in isotropically labeled RNA, FEBS Lett. 362, 156-160.
    • (1995) FEBS Lett. , vol.362 , pp. 156-160
    • Legault, P.1    Juker, F.M.2    Pardi, A.3
  • 13
    • 0028860964 scopus 로고
    • Improved RNA structure determination by detection of NOE contacts to exchange-broadened amino protons
    • Mueller, L., Legault, P. & Pardi. A. (1995) Improved RNA structure determination by detection of NOE contacts to exchange-broadened amino protons, J. Am. Chem. Soc. 117, 11043-11048.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 11043-11048
    • Mueller, L.1    Legault, P.2    Pardi, A.3
  • 14
    • 0029437489 scopus 로고
    • Triple resonance HNNCCCH experiments for correlating exchangeable and nonexchangeable cytidine and uridine base protons in RNA
    • Simorre, J.-P., Zimmermann, G. R., Pardi, A., Farmer, B. T. & Mueller, L. (1995) Triple resonance HNNCCCH experiments for correlating exchangeable and nonexchangeable cytidine and uridine base protons in RNA, J. Biomol. NMR 6, 427-432.
    • (1995) J. Biomol. NMR , vol.6 , pp. 427-432
    • Simorre, J.-P.1    Zimmermann, G.R.2    Pardi, A.3    Farmer, B.T.4    Mueller, L.5
  • 17
    • 0025075436 scopus 로고
    • Synthesis and NMR study of ribooligonucleotides forming a hammerhead-type RNA enzyme system
    • Odai, O., Kodama, H., Hiroaki, H., Sataka, T., Tanaka, T. & Uesugi, S. (1990)Synthesis and NMR study of ribooligonucleotides forming a hammerhead-type RNA enzyme system, Nucleic Acids Res. 18, 5955-5960.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5955-5960
    • Odai, O.1    Kodama, H.2    Hiroaki, H.3    Sataka, T.4    Tanaka, T.5    Uesugi, S.6
  • 18
    • 0023651145 scopus 로고
    • Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides
    • Inoue, T., Hayase, Y., Imura, A., Iwai, S., Miura, K. & Ohtsuka, E. (1987) Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides, Nucleic Acids Res. 15, 6131-6148.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 6131-6148
    • Inoue, T.1    Hayase, Y.2    Imura, A.3    Iwai, S.4    Miura, K.5    Ohtsuka, E.6
  • 19
    • 0023046933 scopus 로고
    • Solid phase synthesis of oligoribonucleotides using o-nitrobenzyl protection of 2′-hydroxyl via a phosphite triester approach
    • Tanaka, T., Tamatsukuri, S. & Ikehara, M. (1986) Solid phase synthesis of oligoribonucleotides using o-nitrobenzyl protection of 2′-hydroxyl via a phosphite triester approach, Nucleic Acids Res. 14, 6265-6279.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 6265-6279
    • Tanaka, T.1    Tamatsukuri, S.2    Ikehara, M.3
  • 20
    • 0025367969 scopus 로고
    • Studies on structure and stabilizing factor of the CU-UCGG hairpin RNA using chemically synthesized oligonucleotides
    • Sataka, T., Hiroaki, H., Oda, Y., Tanaka, T., Ikehara, M. & Uesugi, S. (1990) Studies on structure and stabilizing factor of the CU-UCGG hairpin RNA using chemically synthesized oligonucleotides, Nucleic Acids Res. 18, 3831-3839.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3831-3839
    • Sataka, T.1    Hiroaki, H.2    Oda, Y.3    Tanaka, T.4    Ikehara, M.5    Uesugi, S.6
  • 21
    • 0029400480 scopus 로고
    • NMRPipe: A multidimensional spectral processing system based on UNIX pipes
    • Delaglio, F., Grzesiek, S., Vuister, G., Zhu, G., Pfeifer, J. & Bax, A. (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes, J. Biomol. NMR 6, 277-293.
    • (1995) J. Biomol. NMR , vol.6 , pp. 277-293
    • Delaglio, F.1    Grzesiek, S.2    Vuister, G.3    Zhu, G.4    Pfeifer, J.5    Bax, A.6
  • 25
    • 0027982498 scopus 로고
    • Formation of sheared G:A hase pairs in an RNA duplex modeled after ribozymes, as revealed by NMR
    • Katahira, M., Kanagawa, M., Sato, H., Uesugi, S., Fujii, S., Kohno, T. & Maeda, T. (1994) Formation of sheared G:A hase pairs in an RNA duplex modeled after ribozymes, as revealed by NMR, Nucleic Acids Res. 22, 2752-2759.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2752-2759
    • Katahira, M.1    Kanagawa, M.2    Sato, H.3    Uesugi, S.4    Fujii, S.5    Kohno, T.6    Maeda, T.7
  • 26
    • 0027971706 scopus 로고
    • An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2′-OMe RNA and an oligonucleotide containing a single amide backbone modification
    • Blommers, M. J. J., Pieles, U. & Mesmaeker, A. D. (1994) An approach to the structure determination of nucleic acid analogues hybridized to RNA. NMR studies of a duplex between 2′-OMe RNA and an oligonucleotide containing a single amide backbone modification, Nucleic Acids Res. 20, 4187-4194.
    • (1994) Nucleic Acids Res. , vol.20 , pp. 4187-4194
    • Blommers, M.J.J.1    Pieles, U.2    Mesmaeker, A.D.3
  • 27
    • 0030747007 scopus 로고    scopus 로고
    • Unusual dynamics and pKa shift at the active site of a lead-dependent ribozyme
    • Legault, P. & Pardi, A. (1997) Unusual dynamics and pKa shift at the active site of a lead-dependent ribozyme, J. Am. Chem. Soc. 119, 6621-6628.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 6621-6628
    • Legault, P.1    Pardi, A.2
  • 29
    • 0025998488 scopus 로고
    • Role of divalent metal ions in the hammerhead RNA cleavage reaction
    • Dahm, S. C. & Uhlenbeck, O. C. (1991) Role of divalent metal ions in the hammerhead RNA cleavage reaction, Biochemistry 30, 9464-9469.
    • (1991) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 30
    • 0022433369 scopus 로고
    • Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA
    • Brown, R. S., Dewan, J. C. & Klug, A. (1985) Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA, Biochemistry 24, 4785-4801.
    • (1985) Biochemistry , vol.24 , pp. 4785-4801
    • Brown, R.S.1    Dewan, J.C.2    Klug, A.3
  • 32
    • 0030929889 scopus 로고    scopus 로고
    • A magnesium ion core at the heart of a ribozyme domain
    • Cate, J. H., Hanna, R. L. & Doudna, J. A. (1997) A magnesium ion core at the heart of a ribozyme domain, Nat. Struct. Biol. 4, 553-558.
    • (1997) Nat. Struct. Biol. , vol.4 , pp. 553-558
    • Cate, J.H.1    Hanna, R.L.2    Doudna, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.