-
1
-
-
0025170681
-
The fungal vacuole: Composition, function, and biogenesis
-
Klionsky DJ, Herman PK, Emr SD. The fungal vacuole: composition, function, and biogenesis. Microbiol Rev. 54:1990;266-292.
-
(1990)
Microbiol Rev
, vol.54
, pp. 266-292
-
-
Klionsky, D.J.1
Herman, P.K.2
Emr, S.D.3
-
2
-
-
0030794182
-
Linking cargo to vesicle formation: Receptor tail interactions with coat proteins
-
Kirchhausen T, Bonifacino JS, Riezman H. Linking cargo to vesicle formation: receptor tail interactions with coat proteins. Curr Opin Cell Biol. 9:1997;488-495.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 488-495
-
-
Kirchhausen, T.1
Bonifacino, J.S.2
Riezman, H.3
-
3
-
-
0029875385
-
Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation
-
Chiang HL, Schekman R, Hamamoto S. Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation. J Biol Chem. 271:1996;9934-9941.
-
(1996)
J Biol Chem
, vol.271
, pp. 9934-9941
-
-
Chiang, H.L.1
Schekman, R.2
Hamamoto, S.3
-
4
-
-
0030917085
-
Protein transport from the cytoplasm into the vacuole
-
Klionsky DJ. Protein transport from the cytoplasm into the vacuole. J Membr Biol. 157:1997;105-115.
-
(1997)
J Membr Biol
, vol.157
, pp. 105-115
-
-
Klionsky, D.J.1
-
5
-
-
0031941276
-
Components involved in peroxisome import, biogenesis, proliferation, turnover, and movement
-
Subramani S. Components involved in peroxisome import, biogenesis, proliferation, turnover, and movement. Physiol Rev. 78:1998;171-188.
-
(1998)
Physiol Rev
, vol.78
, pp. 171-188
-
-
Subramani, S.1
-
6
-
-
0027207680
-
Selective autophagy of peroxisomes in methylotrophic yeasts
-
Tuttle DL, Lewin AS, Dunn WA Jr. Selective autophagy of peroxisomes in methylotrophic yeasts. Eur J Cell Biol. 60:1993;283-290.
-
(1993)
Eur J Cell Biol
, vol.60
, pp. 283-290
-
-
Tuttle, D.L.1
Lewin, A.S.2
Dunn W.A., Jr.3
-
7
-
-
0020772844
-
Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes
-
Veenhuis M, Douma A, Harder W, Osumi M. Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes. Arch Microbiol. 134:1983;193-203.
-
(1983)
Arch Microbiol
, vol.134
, pp. 193-203
-
-
Veenhuis, M.1
Douma, A.2
Harder, W.3
Osumi, M.4
-
8
-
-
0028855325
-
Divergent modes of autophagy in the methylotrophic yeast Pichia pastoris
-
Tuttle DL, Dunn WA Jr. Divergent modes of autophagy in the methylotrophic yeast Pichia pastoris. J Cell Sci. 108:1995;25-35.
-
(1995)
J Cell Sci
, vol.108
, pp. 25-35
-
-
Tuttle, D.L.1
Dunn W.A., Jr.2
-
9
-
-
0032482219
-
Peroxisome degradation by microautophagy in P. pastoris: Identification of specific steps and morphological intermediates
-
of outstanding interest. A morphological examination of peroxisome degradation by both macroautophagy and microautophagy. The isolation of pag mutants defective in three different steps of the microautophagic degradation process was performed.
-
Sakai Y, Koller A, Rangell LK, Keller GA, Subramani S. Peroxisome degradation by microautophagy in P. pastoris: identification of specific steps and morphological intermediates. of outstanding interest J Cell Biol. 141:1998;625-636 A morphological examination of peroxisome degradation by both macroautophagy and microautophagy. The isolation of pag mutants defective in three different steps of the microautophagic degradation process was performed.
-
(1998)
J Cell Biol
, vol.141
, pp. 625-636
-
-
Sakai, Y.1
Koller, A.2
Rangell, L.K.3
Keller, G.A.4
Subramani, S.5
-
10
-
-
0018090257
-
Degradation of microbodies in relation to activities of alcohol oxidase and catalase in Candida boidinii
-
Bormann C, Sahm H. Degradation of microbodies in relation to activities of alcohol oxidase and catalase in Candida boidinii. Arch Microbiol. 117:1978;67-72.
-
(1978)
Arch Microbiol
, vol.117
, pp. 67-72
-
-
Bormann, C.1
Sahm, H.2
-
11
-
-
0028855063
-
Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha
-
Titorenko VI, Keizer I, Harder W, Veenhuis M. Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha. J Bacteriol. 177:1995;357-363.
-
(1995)
J Bacteriol
, vol.177
, pp. 357-363
-
-
Titorenko, V.I.1
Keizer, I.2
Harder, W.3
Veenhuis, M.4
-
12
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science. 260:1993;88-91.
-
(1993)
Science
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
13
-
-
0027256130
-
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole
-
Stack JH, Herman PK, Schu PV, Emr SD. A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J. 12:1993;2195-2204.
-
(1993)
EMBO J
, vol.12
, pp. 2195-2204
-
-
Stack, J.H.1
Herman, P.K.2
Schu, P.V.3
Emr, S.D.4
-
14
-
-
0030883562
-
Glucose induced microautophagy in Pichia pastoris requires the α-subunit of phosphofructokinase
-
of outstanding interest. This paper describes the cloning of GSA1, which codes for the alpha subunit of phosphofructokinase (PFK1). The catalytic site of PFK1 is not required for peroxisomal degradation, suggesting that the protein acts independently of its role in glycolysis.
-
Yuan WY, Tuttle DL, Shi Y-J, Ralph GS, Dunn WA Jr. Glucose induced microautophagy in Pichia pastoris requires the α-subunit of phosphofructokinase. of outstanding interest J Cell Sci. 110:1997;1935-1945 This paper describes the cloning of GSA1, which codes for the alpha subunit of phosphofructokinase (PFK1). The catalytic site of PFK1 is not required for peroxisomal degradation, suggesting that the protein acts independently of its role in glycolysis.
-
(1997)
J Cell Sci
, vol.110
, pp. 1935-1945
-
-
Yuan, W.Y.1
Tuttle, D.L.2
Shi Y-J3
Ralph, G.S.4
Dunn W.A., Jr.5
-
15
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J Cell Biol. 119:1992;301-311.
-
(1992)
J Cell Biol
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
16
-
-
0027304446
-
Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae
-
Thorsness PE, White KH, Fox TD. Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae. Mol Cell Biol. 13:1993;5418-5426.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5418-5426
-
-
Thorsness, P.E.1
White, K.H.2
Fox, T.D.3
-
17
-
-
0027979074
-
Mitochondrial morphological and functional defects in yeast caused by yme1 are suppressed by mutation of a 26S protease subunit homologue
-
Campbell CL, Tanaka N, White KH, Thorsness PE. Mitochondrial morphological and functional defects in yeast caused by yme1 are suppressed by mutation of a 26S protease subunit homologue. Mol Biol Cell. 5:1994;899-905.
-
(1994)
Mol Biol Cell
, vol.5
, pp. 899-905
-
-
Campbell, C.L.1
Tanaka, N.2
White, K.H.3
Thorsness, P.E.4
-
18
-
-
0025932822
-
Selective inactivation of alcohol oxidase in two peroxisome-deficient mutants of the yeast Hansenula polymorpha
-
Van der Klei IJ, Harder W, Veenhuis M. Selective inactivation of alcohol oxidase in two peroxisome-deficient mutants of the yeast Hansenula polymorpha. Yeast. 7:1991;813-821.
-
(1991)
Yeast
, vol.7
, pp. 813-821
-
-
Van Der Klei, I.J.1
Harder, W.2
Veenhuis, M.3
-
19
-
-
0029844569
-
Isolation of degradation-deficient mutants defective in the targeting of fructose-1,6-bisphosphatase into the vacuole for degradation in Saccharomyces cerevisiae
-
Hoffman M, Chiang H-L. Isolation of degradation-deficient mutants defective in the targeting of fructose-1,6-bisphosphatase into the vacuole for degradation in Saccharomyces cerevisiae. Genetics. 143:1996;1555-1566.
-
(1996)
Genetics
, vol.143
, pp. 1555-1566
-
-
Hoffman, M.1
Chiang H-L2
-
20
-
-
0031019152
-
Identification of novel vesicles in the cytosol to vacuole degradation pathway
-
of outstanding interest. This paper describes the purification of vesicles involved in the vacuolar delivery of the glycolytic enzyme fructose-1,6-bisphosphatase.
-
Huang P-H, Chiang H-L. Identification of novel vesicles in the cytosol to vacuole degradation pathway. of outstanding interest J Cell Biol. 136:1997;803-810 This paper describes the purification of vesicles involved in the vacuolar delivery of the glycolytic enzyme fructose-1,6-bisphosphatase.
-
(1997)
J Cell Biol
, vol.136
, pp. 803-810
-
-
Huang P-H1
Chiang H-L2
-
21
-
-
0032559855
-
Vid24p, a novel protein localized to the fructose-1,6-bisphosphatase-containing vesicles, regulates targeting of fructose-1,6-bisphosphatase from the vesicles to the vacuole for degradation in S. cerevisiae
-
of outstanding interest. This paper describes the first characterization of a mutant involved in fructose-1,6-bisphosphatase degradation. Vid24p is localized to fructose-1,6-bisphosphatase-containing vesicles, and functional Vid24p is required for the delivery of these vesicles to the vacuole.
-
Chiang M-C, Chiang H-L. Vid24p, a novel protein localized to the fructose-1,6-bisphosphatase-containing vesicles, regulates targeting of fructose-1,6-bisphosphatase from the vesicles to the vacuole for degradation in S. cerevisiae. of outstanding interest J Cell Biol. 140:1998;1347-1356 This paper describes the first characterization of a mutant involved in fructose-1,6-bisphosphatase degradation. Vid24p is localized to fructose-1,6-bisphosphatase-containing vesicles, and functional Vid24p is required for the delivery of these vesicles to the vacuole.
-
(1998)
J Cell Biol
, vol.140
, pp. 1347-1356
-
-
Chiang M-C1
Chiang H-L2
-
22
-
-
0032488997
-
In vitro reconstitution of glucose-induced targeting of fructose-1,6-bisphosphatase into the vacuole in semi-intact yeast cells
-
of outstanding interest. The authors describe the development of the first in vitro assay for the vacuolar uptake of fructose-1,6-bisphosphatase. The in vitro targeting event is stimulated in cells treated with glucose, suggesting that it represents the in vivo targeting event.
-
Shieh H-L, Chiang H-L. In vitro reconstitution of glucose-induced targeting of fructose-1,6-bisphosphatase into the vacuole in semi-intact yeast cells. of outstanding interest J Biol Chem. 273:1998;3381-3387 The authors describe the development of the first in vitro assay for the vacuolar uptake of fructose-1,6-bisphosphatase. The in vitro targeting event is stimulated in cells treated with glucose, suggesting that it represents the in vivo targeting event.
-
(1998)
J Biol Chem
, vol.273
, pp. 3381-3387
-
-
Shieh H-L1
Chiang H-L2
-
23
-
-
0028230738
-
Ultrastructural analysis of the autophagic process in yeast: Detection of autophagosomes and their characterization
-
Baba M, Takeshige K, Baba N, Ohsumi Y. Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization. J Cell Biol. 124:1994;903-913.
-
(1994)
J Cell Biol
, vol.124
, pp. 903-913
-
-
Baba, M.1
Takeshige, K.2
Baba, N.3
Ohsumi, Y.4
-
24
-
-
0029414780
-
Analysis of the membrane structures involved in autophagy in yeast by freeze-replica method
-
Baba M, Osumi M, Ohsumi Y. Analysis of the membrane structures involved in autophagy in yeast by freeze-replica method. Cell Struct Funct. 20:1995;465-471.
-
(1995)
Cell Struct Funct
, vol.20
, pp. 465-471
-
-
Baba, M.1
Osumi, M.2
Ohsumi, Y.3
-
25
-
-
0028222874
-
Autophagy and related mechanisms of lysosome-mediated protein degradation
-
Dunn WA. Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell Biol. 4:1994;139-143.
-
(1994)
Trends Cell Biol
, vol.4
, pp. 139-143
-
-
Dunn, W.A.1
-
26
-
-
0030338132
-
Structural aspects of autophagy
-
Seglen PO, Berg TO, Blankson H, Fengsrud M, Holen I, Stromhaug PE. Structural aspects of autophagy. Adv Exp Med Biol. 389:1996;103-111.
-
(1996)
Adv Exp Med Biol
, vol.389
, pp. 103-111
-
-
Seglen, P.O.1
Berg, T.O.2
Blankson, H.3
Fengsrud, M.4
Holen, I.5
Stromhaug, P.E.6
-
28
-
-
0030003893
-
Ultrastructural and biochemical characterization of autophagy in higher plant cells subjected to carbon deprivation: Control by the supply of mitochondria with respiratory substrates
-
Aubert S, Gout E, Bligny R, Marty-Mazars D, Barrieu F, Alabouvette J, Marty F, Douce R. Ultrastructural and biochemical characterization of autophagy in higher plant cells subjected to carbon deprivation: control by the supply of mitochondria with respiratory substrates. J Cell Biol. 133:1996;1251-1263.
-
(1996)
J Cell Biol
, vol.133
, pp. 1251-1263
-
-
Aubert, S.1
Gout, E.2
Bligny, R.3
Marty-Mazars, D.4
Barrieu, F.5
Alabouvette, J.6
Marty, F.7
Douce, R.8
-
29
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333:1993;169-174.
-
(1993)
FEBS Lett
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
30
-
-
0027936092
-
Isolation of autophagocytosis mutants of Saccharomyces cerevisiae
-
Thumm M, Egner R, Koch M, Schlumpberger M, Straub M, Veenhuis M, Wolf DH. Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. FEBS Lett. 349:1994;275-280.
-
(1994)
FEBS Lett
, vol.349
, pp. 275-280
-
-
Thumm, M.1
Egner, R.2
Koch, M.3
Schlumpberger, M.4
Straub, M.5
Veenhuis, M.6
Wolf, D.H.7
-
31
-
-
0030608395
-
Structural and functional analyses of APG5, a gene involved in autophagy in yeast
-
Kametaka S, Matsuura A, Wada Y, Ohsumi Y. Structural and functional analyses of APG5, a gene involved in autophagy in yeast. Gene. 178:1996;139-143.
-
(1996)
Gene
, vol.178
, pp. 139-143
-
-
Kametaka, S.1
Matsuura, A.2
Wada, Y.3
Ohsumi, Y.4
-
32
-
-
0030919092
-
Analysis of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae
-
Funakoshi T, Matsuura A, Noda T, Oshumi Y. Analysis of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene. 192:1997;207-213.
-
(1997)
Gene
, vol.192
, pp. 207-213
-
-
Funakoshi, T.1
Matsuura, A.2
Noda, T.3
Oshumi, Y.4
-
33
-
-
0031038649
-
AUT1, a gene essential for autophagocytosis in the yeast Saccharomyces cerevisiae
-
of special interest. The authors describe the cloning of AUT1, which codes for a novel protein required for both autophagy and aminopeptidase I transport.
-
Schlumpberger M, Schaeffeler E, Straub M, Bredschneider M, Wolf DH, Thumm M. AUT1, a gene essential for autophagocytosis in the yeast Saccharomyces cerevisiae. of special interest J Bacteriol. 179:1997;1068-1076 The authors describe the cloning of AUT1, which codes for a novel protein required for both autophagy and aminopeptidase I transport.
-
(1997)
J Bacteriol
, vol.179
, pp. 1068-1076
-
-
Schlumpberger, M.1
Schaeffeler, E.2
Straub, M.3
Bredschneider, M.4
Wolf, D.H.5
Thumm, M.6
-
34
-
-
0030983504
-
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
-
of special interest. This paper describes the cloning of APG1, which codes for a novel serine/threonine protein kinase.
-
Matsuura A, Tsukada M, Wada Y, Ohsumi Y. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. of special interest Gene. 192:1997;245-250 This paper describes the cloning of APG1, which codes for a novel serine/threonine protein kinase.
-
(1997)
Gene
, vol.192
, pp. 245-250
-
-
Matsuura, A.1
Tsukada, M.2
Wada, Y.3
Ohsumi, Y.4
-
35
-
-
0031452311
-
Mutational analysis of Csc1/Vps4p: Involvement of endosome in regulation of autophagy in yeast
-
of outstanding interest. The isolation of two complementation groups of mutants that constitutively undergo autophagic delivery is described. The cloning of CSC1 revealed that it is identical to VPS4, suggesting a role for the endosome in regulating autophagy.
-
Shirahama K, Noda T, Oshumi Y. Mutational analysis of Csc1/Vps4p: involvement of endosome in regulation of autophagy in yeast. of outstanding interest Cell Struct Funct. 22:1997;501-509 The isolation of two complementation groups of mutants that constitutively undergo autophagic delivery is described. The cloning of CSC1 revealed that it is identical to VPS4, suggesting a role for the endosome in regulating autophagy.
-
(1997)
Cell Struct Funct
, vol.22
, pp. 501-509
-
-
Shirahama, K.1
Noda, T.2
Oshumi, Y.3
-
36
-
-
0030945105
-
Signal transduction pathways in macroautophagy
-
Codogno P, Ogier-Denis E, Houri J-J. Signal transduction pathways in macroautophagy. Cell Signal. 9:1997;125-130.
-
(1997)
Cell Signal
, vol.9
, pp. 125-130
-
-
Codogno, P.1
Ogier-Denis, E.2
Houri J-J3
-
37
-
-
0030345672
-
Mechanism of autophagy in permeabilized hepatocytes: Evidence for regulation by GTP binding proteins
-
Kadowaki M, Venerando R, Miotto G, Mortimore GE. Mechanism of autophagy in permeabilized hepatocytes: evidence for regulation by GTP binding proteins. Adv Exp Med Biol. 389:1996;113-119.
-
(1996)
Adv Exp Med Biol
, vol.389
, pp. 113-119
-
-
Kadowaki, M.1
Venerando, R.2
Miotto, G.3
Mortimore, G.E.4
-
38
-
-
0028985249
-
i3-protein controls autophagic sequestration in the human colon cancer cell line HT-29
-
i3-protein controls autophagic sequestration in the human colon cancer cell line HT-29. J Biol Chem. 270:1995;13-16.
-
(1995)
J Biol Chem
, vol.270
, pp. 13-16
-
-
Ogier-Denis, E.1
Couvineau, A.2
Maoret, J.J.3
Houri, J.J.4
Bauvy, C.5
De Stefanis, D.6
Isidoro, C.7
Laburthe, M.8
Codogno, P.9
-
40
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
Blommaart EF, Luiken JJ, Blommaart PJ, van Woerkom GM, Meijer AJ. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J Biol Chem. 270:1995;2320-2326.
-
(1995)
J Biol Chem
, vol.270
, pp. 2320-2326
-
-
Blommaart, E.F.1
Luiken, J.J.2
Blommaart, P.J.3
Van Woerkom, G.M.4
Meijer, A.J.5
-
41
-
-
0032512636
-
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
-
of special interest. The findings of the authors implicate Tor, a yeast phosphatidylinositol kinase homologue, in the regulation of autophagy in yeast.
-
Noda T, Ohsumi Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. of special interest J Biol Chem. 273:1998;3963-3966 The findings of the authors implicate Tor, a yeast phosphatidylinositol kinase homologue, in the regulation of autophagy in yeast.
-
(1998)
J Biol Chem
, vol.273
, pp. 3963-3966
-
-
Noda, T.1
Ohsumi, Y.2
-
42
-
-
0026640551
-
Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway
-
Klionsky DJ, Cueva R, Yaver DS. Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J Cell Biol. 119:1992;287-299.
-
(1992)
J Cell Biol
, vol.119
, pp. 287-299
-
-
Klionsky, D.J.1
Cueva, R.2
Yaver, D.S.3
-
43
-
-
0031576988
-
Folding of the presequence of yeast pAPI into an amphipathic helix determines transport of the protein from the cytosol to the vacuole
-
Martinez E, Jimenez MA, Segui-Real B, Vandekerckhove J, Sandoval IV. Folding of the presequence of yeast pAPI into an amphipathic helix determines transport of the protein from the cytosol to the vacuole. J Mol Biol. 267:1997;1124-1138.
-
(1997)
J Mol Biol
, vol.267
, pp. 1124-1138
-
-
Martinez, E.1
Jimenez, M.A.2
Segui-Real, B.3
Vandekerckhove, J.4
Sandoval, I.V.5
-
44
-
-
0029916949
-
Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I
-
Oda MN, Scott SV, Hefner-Gravink A, Caffarelli AD, Klionsky DJ. Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I. J Cell Biol. 132:1996;999-1010.
-
(1996)
J Cell Biol
, vol.132
, pp. 999-1010
-
-
Oda, M.N.1
Scott, S.V.2
Hefner-Gravink, A.3
Caffarelli, A.D.4
Klionsky, D.J.5
-
45
-
-
0030997923
-
Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway
-
of outstanding interest. This paper characterized the structure of amino peptidase I during transport. Amino peptidase I was found to be assembled into a dodecamer of approximately 732 kDa immediately after synthesis, and was maintained in the oligomeric form throughout the targeting process.
-
Kim J, Scott SV, Oda MN, Klionsky DJ. Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway. of outstanding interest J Cell Biol. 137:1997;609-618 This paper characterized the structure of amino peptidase I during transport. Amino peptidase I was found to be assembled into a dodecamer of approximately 732 kDa immediately after synthesis, and was maintained in the oligomeric form throughout the targeting process.
-
(1997)
J Cell Biol
, vol.137
, pp. 609-618
-
-
Kim, J.1
Scott, S.V.2
Oda, M.N.3
Klionsky, D.J.4
-
46
-
-
0028800171
-
Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway
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Harding TM, Morano KA, Scott SV, Klionsky DJ. Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol. 131:1995;591-602.
-
(1995)
J Cell Biol
, vol.131
, pp. 591-602
-
-
Harding, T.M.1
Morano, K.A.2
Scott, S.V.3
Klionsky, D.J.4
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47
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0029953575
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Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway
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Harding TM, Hefner-Gravink A, Thumm M, Klionsky DJ. Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway. J Biol Chem. 271:1996;17621-17624.
-
(1996)
J Biol Chem
, vol.271
, pp. 17621-17624
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-
Harding, T.M.1
Hefner-Gravink, A.2
Thumm, M.3
Klionsky, D.J.4
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48
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0029913505
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Cytoplasm to vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole
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Scott SV, Hefner-Gravink A, Morano KA, Noda T, Ohsumi Y, Klionsky DJ. Cytoplasm to vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc Natl Acad Sci USA. 93:1996;12304-12308.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12304-12308
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Scott, S.V.1
Hefner-Gravink, A.2
Morano, K.A.3
Noda, T.4
Ohsumi, Y.5
Klionsky, D.J.6
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49
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0030852279
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Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism
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of outstanding interest. The authors describe the biochemical characterization of the cytosol-to-vacuole targeting pathway. The identification of amino peptidase I in bound intermediates, cytosolic vesicles and subvacuolar vesicles supports an autophagic model for protein uptake by this pathway.
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Scott SV, Baba M, Ohsumi Y, Klionsky DJ. Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism. of outstanding interest J Cell Biol. 138:1997;37-44 The authors describe the biochemical characterization of the cytosol-to-vacuole targeting pathway. The identification of amino peptidase I in bound intermediates, cytosolic vesicles and subvacuolar vesicles supports an autophagic model for protein uptake by this pathway.
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(1997)
J Cell Biol
, vol.138
, pp. 37-44
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Scott, S.V.1
Baba, M.2
Ohsumi, Y.3
Klionsky, D.J.4
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50
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0031417385
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Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome
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of outstanding interest. The authors give a comparison of amino-peptidase I targeting in rich media and starvation conditions, demonstrating that structures morphologically similar to autophagosomes form in rich media and are used for the specific targeting of amino-peptidase I. The vesicles formed in rich media are called Cvt vesicles and are smaller than autophagosomes and do not appear to include bulk cytosol.
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Baba M, Osumi M, Scott SV, Klionsky DJ, Ohsumi Y. Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome. of outstanding interest J Cell Biol. 139:1997;1687-1695 The authors give a comparison of amino-peptidase I targeting in rich media and starvation conditions, demonstrating that structures morphologically similar to autophagosomes form in rich media and are used for the specific targeting of amino-peptidase I. The vesicles formed in rich media are called Cvt vesicles and are smaller than autophagosomes and do not appear to include bulk cytosol.
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(1997)
J Cell Biol
, vol.139
, pp. 1687-1695
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Baba, M.1
Osumi, M.2
Scott, S.V.3
Klionsky, D.J.4
Ohsumi, Y.5
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51
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0030807624
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A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole
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of special interest. This paper describes the characterization of the vacuolar t-SNARE Vam3p. Vam3p is necessary for the correct targeting of multiple vacuolar hydrolases. In addition, both autophagy and cytoplasm-to-vacuole transport are disrupted in temperature-sensitive vam3 cells, suggesting that Vam3p is a multispecificity receptor for fusion at the vacuole membrane.
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Darsow T, Rieder SE, Emr SD. A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. of special interest J Cell Biol. 138:1997;517-529 This paper describes the characterization of the vacuolar t-SNARE Vam3p. Vam3p is necessary for the correct targeting of multiple vacuolar hydrolases. In addition, both autophagy and cytoplasm-to-vacuole transport are disrupted in temperature-sensitive vam3 cells, suggesting that Vam3p is a multispecificity receptor for fusion at the vacuole membrane.
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(1997)
J Cell Biol
, vol.138
, pp. 517-529
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Darsow, T.1
Rieder, S.E.2
Emr, S.D.3
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52
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0030940407
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Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae
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Nakamura N, Hirata A, Ohsumi Y, Wada Y. Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae. J Biol Chem. 272:1997;11344-11349.
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(1997)
J Biol Chem
, vol.272
, pp. 11344-11349
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Nakamura, N.1
Hirata, A.2
Ohsumi, Y.3
Wada, Y.4
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53
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0030830765
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A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole
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of special interest. This paper demonstrates that Vps18p function is required for biosynthetic, endocytic and autophagic protein transport to the vacuole.
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Rieder SE, Emr SD. A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. of special interest Mol Biol Cell. 8:1997;2307-2327 This paper demonstrates that Vps18p function is required for biosynthetic, endocytic and autophagic protein transport to the vacuole.
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(1997)
Mol Biol Cell
, vol.8
, pp. 2307-2327
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Rieder, S.E.1
Emr, S.D.2
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