Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat

British Journal of Pharmacology

Volumn 118, Issue 1, 1996, Pages 198-204

  Ruetten, Hartmut ^a   Thiemermann, Christoph ^a   Vane, John R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cytokines; Endothelin receptors; Endotoxic shock; Interferon ; SB 209670; Tumour necrosis factor ; Vascular hyporeactivity

Indexed keywords

3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; GAMMA INTERFERON; NORADRENALIN; TUMOR NECROSIS FACTOR ALPHA; UREA;

ACID BASE BALANCE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENDOTOXEMIA; HEMODYNAMICS; HYPERVENTILATION; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FAILURE; KIDNEY FUNCTION; LIVER CELL DAMAGE; LIVER DYSFUNCTION; MALE; MEAN ARTERIAL PRESSURE; METABOLIC ACIDOSIS; MULTIPLE ORGAN FAILURE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; SHOCK; SURVIVAL; UREA BLOOD LEVEL; VASOCONSTRICTION;

EID: 0029925566     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15386.x     Document Type: Article

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