Annexin VI overexpression targeted to heart alters cardiomyocyte function in transgenic mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 3 39-3, 1996, Pages

  Gunteski Hamblin, Ann Marie ^a   Song, Guojle ^b   Walsh, Richard A ^b   Frenzke, Marie ^b   Boivin, Gregory P ^b   Dorn II, Gerald W ^b   Kaetzel, Marcia A ^b   Horseman, Nelson D ^b   Dedman, John R ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

annexins; binding proteins; calcium; cardiomyopathy

Indexed keywords

CALCIUM ION; CALPHOBINDIN II; COMPLEMENTARY DNA; MYOSIN HEAVY CHAIN; PHOSPHOLIPID BINDING PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CARDIOMEGALY; CONTROLLED STUDY; HEART ATRIUM; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE; LYMPHOCYTIC INFILTRATION; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

EID: 0029932245     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.3.h1091     Document Type: Article

References (34)

1. Borzak, S., R. A. Kelley, B. A. Kraemer, Y. Matoba, J. D. Maesh, and M. Reers. In situ calibration of fura-2 and BCECF fluorescence in adult rat ventricular myocytes. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H973-H981, 1990.
2. Buttrick, P., A. Malhotra, S. Factor, D. Geenan, L. Leinwand, and J. Scheuer. Effect of aging and hypertension on inyosin biochemistry and gene expression in the rat heart. Circ. Res. 68: 645-652, 1991.
3. Clark, W. A., R. A. Chizzonite, A. W. Everett, M. Rabinowitz, and R. Zak. Species correlations between cardiac isomyosins. J. Biol. Chem. 257: 5449-5454, 1982.
4. 2+-binding protein p68: a novel member of a protein family. Eur. Mol. Biol. Organ. J. 7: 21-27, 1988
5. Dechesne, C. A., J. Léger, P. Bouvagnet, H. Mairhofer, and J. J. Léger. Local diversity of myosin expression in mammalian atrial muscles. Circ. Res. 57: 767-775, 1985.
6. 2+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa calcimedin). J. Biol. Chem. 265: 15894-15899, 1990.
7. Dorn, G. W. II, J. Robbins, N. Ball, and R. A. Walsh. Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice. Am. J. Physiol. 267 (Heart Circ Physiol. 36): H400-H405, 1994.
8. 2+-dependent atrial secretory granule-binding proteins. Hypertension Dallas 18: 648-656, 1991.
9. Doubell, A. F., C. Lazure, C. Charbonneau, and G. Thibault. Identification and immunolocalisation of annexin V and VI, the major cardiac annexins, in rat heart. Cardiovascular Res. 27: 1359-1367, 1993.
10. Gruver, C. L., F. DeMayo, M. A. Goldstein, and A. R. Means. Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. Endocrinology 133: 376-381, 1993.
11. Gulick, J., A. Subramaniam, J. Neumann, and J. Robbins. Isolation and characterization of the mouse cardiac myosin heavy chain genes. J. Biol. Chem. 266: 9180-9185, 1991.
12. 2+-release channel requires intact annexin VI. J. Cell Biochem. 46: 86-93, 1991.
13. Hogan, B., F. Constantini, and E. Lacy. Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1986.
14. 2--binding protein localized at the sarcolemma of secretory atrial myocytes. Circ. Res. 70: 370-381, 1992.
15. 2+-dependent phospholipid-binding proteins. J. Biol. Chem. 264: 14463-14470, 1989.
16. Kaetzel, M. A., G. Pula, B. Campos, P. Uhrin, N. Horseman, J. R. Dedman. Annexin VI isoforms are differentially expressed in mammalian tissues. Biochim. Biophys. Acta 1223: 368-374. 1994.
17. Katz, E. B., M. E. Steinhelper, J. B. Delcarpio, A. I. Daud, W. C. Claycomb, and L. J. Field. Cardiomyocyte proliferation in mice expressing α-cardiac myosin heavy chain-SV40 T-antigen transgenes. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H1867-H1876, 1992.
18. Kurabayashi, M., Y. Shibasaki, I. Komuro, H. Tsuchimochi, and Y. Yazaki. The myosin gene switching in human cardiac hypertrophy. Jpn. Circ. J. 54: 1192-1205, 1990.
19. 2+ and the heart: exchange at the tissue, cell, and organelle levels. FASEB J. 6: 893-902, 1992.
20. Lin, Z. W., M. P. Wenderoth, and B. R. Eisenberg. Individual rabbit cardiac myocytes have different thresholds for alpha myosin heavy chain regulation by thyroid hormone. Am. J. Anat. 185: 455-461, 1989.
21. Lompre, A., B. Nadal-Ginard, and V. Mahdavi. Expression of the cardiac ventricular α- and β-myosin heavy chain genes is developmentally and hormonally regulated. J. Biol. Chem. 259: 6437-6446, 1984.
22. Luckcuck, T., and J. H. Walker. Annexins in porcine heart. Biochem. Soc. Trans. 21: 437S, 1993.
23. Lyons, G. E., S. Schiaffino, D. Sassoon, P. Barton, and M. Buckingham. Developmental regulation of myosin gene expression in mouse cardiac muscle. J. Cell Biol. 111: 2427-2436, 1990.
24. Mathew, J. K., J. M. Krolak, and J. R. Dedman. Calcimedins: purification and characterization from chicken gizzard and rat and bovine livers. J. Cell Biochem. 32: 223-227, 1986.
25. 2-adrenergic receptor. Science Wash. DC 264: 582-586, 1994.
26. Molkentin, J. D., and M. J. Markham. Myocyte-specific enhancer-binding factor (MEF-2) regulates α-cardiac myosin heavy chain gene expression in vitro and in vivo. J. Biol. Chem. 268: 19512-19520, 1993.
27. 2+-binding protein of the lipocortin family. Eur. J. Biochem. 177: 21-27, 1988.
28. 2+-binding protein. FEBS Lett. 261: 299-302, 1990.
29. Ng, W. A., I. L. Grupp, A. Subramaniam, and J. Robbins. Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart. Circ. Res. 68: 1742-1750, 1991
30. Pula, G., R. Bianchi, P. Ceccarelli, I. Giambanco, and R. Donato. Characterization of mammalian heart annexins with special reference to CaBP33 (annexin V). FEBS Lett. 277: 53-58, 1990.
31. 2+ATPase and myosin heavy chain α gene expression in cardiac myocytes. J. Biol. Chem. 266: 8638-8646, 1991.
32. 2+ exchange activity. Biochem. Biophys. Res. Commun. 172: 1067-1072, 1990.
33. Subramaniam, A., W. K. Jones, J. Gulick, S. Wert, J. Neumann, and J. Robbins. Tissue-specific regulation of the α-myosin heavy chain gene promoter in transgenic mice. J. Biol. Chem. 266: 24613-24620, 1991.
34. Sudhof, T. C., C. A. Slaughter, I. Leznicki, P. Barjon, and G. A. Reynolds. Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins. Proc. Natl. Acad. Sci. USA 85: 664-668, 1988.