Hepatitis C virus infection: Review and implications for the dentist

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

Volumn 86, Issue 1, 1998, Pages 8-22

  Lodi, G ^a   Porter, S R ^a   Scully, C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON;

DISEASE TRANSMISSION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LICHEN PLANUS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER TUMOR; MOUTH DISEASE; OCCUPATIONAL DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SIALOADENITIS; VIROLOGY;

CARCINOMA, HEPATOCELLULAR; DISEASE TRANSMISSION, PATIENT-TO-PROFESSIONAL; HEPACIVIRUS; HEPATITIS C; HEPATITIS C, CHRONIC; HUMANS; INTERFERON-ALPHA; LICHEN PLANUS, ORAL; LIVER CIRRHOSIS; LIVER NEOPLASMS; MOUTH DISEASES; OCCUPATIONAL DISEASES; SIALADENITIS;

EID: 0032112345     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1079-2104(98)90143-3     Document Type: Review

References (270)

1. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989;244:359-62.
2. Heinz FX. Comparative molecular biology of flaviviruses and hepatitis C virus. Arch Virol Suppl 1992;4:163-71.
3. van Doom LJ. Review: molecular biology of the hepatitis C virus. J Meal Virol 1994;43:345-56.
4. Brechot C. Hepatitis C virus: molecular biology and genetic variability. Dig Dis Sci 1996;41:6S-21S.
5. Yuasa T, Ishikawa G, Manabe S, Sekiguchi S, Takeuchi K, Miyamura T. The particle size of hepatitis C virus estimated by filtration through microporous regenerated cellulose fibre. J Gen Virol 1991;72:2021-4.
6. Kaito M, Watanabe S, Tsukiyama KK, et al. Hepatitis C virus particle detected by immunoelectron microscopic study. J Gen Virol 1994;75:1755-60.
7. Li X, Jeffers L J, Shao L, et al. Identification of hepatitis C virus by immunoelectron microscopy. J Viral Hepat 1995;2:227-34.
8. Yoshikura H, Hijikata M, Nakajima N, Shimizu YK. Replication of hepatitis C virus. J Viral Hepat 1996;3:3-10.
9. Sherker AH, Twu JS, Reyes GR, Robinson WS. Presence of viral replicative intermediates in the liver and serum of patients infected with hepatitis C virus. J Med Virol 1993;39:91-6.
10. Qian C, Camps J, Maluenda MD, Civeira MP, Prieto J. Replication of hepatitis C virus in peripheral blood mononuclear cells. Effect of alpha-interferon therapy. J Hepatol 1992;16:380-3.
11. Liu FH, Tian GS, Fu XX. Detection of plus and minus strand hepatitis C virus RNA in peripheral blood mononuclear cells and spermatid. Chung Hua I Hsueh Tsa Chih 1994;74:284-6.
12. Kobayashi S, Hayashi H, Itoh Y, Asano T, Isono K. Detection of minus-strand hepatitis C virus RNA in tumor tissues of hepatocellular carcinoma. Cancer 1994;73:48-52.
13. Bocher WO, Lohr HF, Steegmuller KW, et al. Detection of hepatitis C virus replication in ovarian metastases of a patient with hepatocellular carcinoma. J Hepatol 1994;21:47-51.
14. De-Vita S, Sansonno D, Dolcetti R, et al. Hepatitis C virus within a malignant lymphoma lesion in the course of type II mixed cryoglobulinemia. Blood 1995;86:1887-92.
15. Oshima M, Tsuchiya M, Yagasaki M, et al. cDNA clones of Japanese hepatitis C virus genomes derived from a single patient show sequence heterogeneity. J Gen Virol 1991;72:2805-9.
16. Choo QL, Richman KH, Han JH, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 1991;88:2451-5.
17. Miyakawa H, Okamoto H, Mayumi M. Classifying hepatitis C virus genotypes. Molecular Medicine Today 1995;1:20-5.
18. Simmonds P, Alberti A, Alter HJ, et al. A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 1994;19:1321-4.
19. Nakao T, Enomoto N, Takada N, Takada A, Date T. Typing of hepatitis C virus genomes by restriction fragment length polymorphism. J Gen Virol 1991;72:2105-12.
20. Stuyver L, Rossau R, Wyseur A, et al. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol 1993;74:1093-102.
21. Okamoto H, Sugiyama Y, Okada S, et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992;73:673-9.
22. Machida A, Ohnuma H, Tsuda F, et al. Two distinct subtypes of hepatitis C virus defined by antibodies directed to the putative core protein. Hepatology 1992;16:886-91.
23. Simmonds P, Rose KA, Graham S, et al. Mapping of serotypespecific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): use of type specific peptides to serologically differentiate infections with HCV types 1,2, and 3. J Clin Microbiol 1993;31:1493-503.
24. Tisminetzky S, Gerotto M, Pontisso P, et al. Comparison of genotyping and serotyping methods for the identification of hepatitis C virus types. J Virol Methods 1995;55:303-7.
25. Lee JH, Roth WK, Zeuzem S. Evaluation and comparison of different hepatitis C virus genotyping and serotyping assays. J Hepatol 1997;26:1001-9.
26. Lau JY, Mizokami M, Kolberg JA, et al. Application of six hepatitis C virus genotyping systems to sera from chronic hepatitis C patients in the United States. J Infect Dis 1995;171:281-9.
27. McOmish F, Yap PL, Dow BC, et al. Geographical distribution of hepatitis C virus genotypes in blood donors: an international collaborative survey. J Clin Microbiol 1994;32:884-92.
28. Anonymous. Genetic diversity of hepatitis C virus: implications for pathogenesis, treatment, and prevention. Report of a meeting of Physicians and Scientists clinical conference. Lancet 1995;345:562-6.
29. Smith DB, Pontisso P. Heterogeneity of hepatitis C virus. Bailliere's Clin Gastroenterol 1996;10:243-55.
30. Sharara AI, Hunt CM, Hamilton JD. Hepatitis C. Ann Intern Med 1996;125:658-68.
31. McLindon JP, Paver WK, Babbs C, et al. Hepatitis C-related chronic liver disease among asymptomatic blood donors in the northwest of England. J Infect 1995;30:253-9.
32. Nordoy I, Schrumpf E, Elgjo K, et al. Liver disease in antihepatitis C virus-positive Norwegian blood donors. Scand J Gastroenterol 1994;29:77-81.
33. Van Hoof M, Waterloos H, Comu C, De BM, Geubel AP. Anti-hepatitis C virus positivity (HCV) in Belgian volunteer blood donors: source of contamination and HCV-testing among donors and related recipients. Acta Clin Belg 1995;50:335-42.
34. Ehrmann J, Zakova A, Krc I. Anti-HCV positivity in blood donors. Vnitr Lek 1995;41:227-9.
35. Klofera M, Chalupa P, Jezek P. Hepatitis C antibodies (anti-HCV) in blood donors at the transfusion department in Brno. Cas Lek Cesk 1994;133:459-62.
36. Aguelles O, Janot C. Epidemiology of anti-HCV antibodies in France. Viral Hepatitis Study Group of the French Blood Transfusion Society. Arch Virol Suppl 1992;4:249-52.
37. Aussel L, Denis F, Ranger S, et al. Prevalence of antibodies to the hepatitis C virus in pregnant foreign residents in France. Pathol Biol (Paris) 1991;39:991-6.
38. Marcellin P, Bernuau J, Martinot-Peignoux M, et al. Prevalence of hepatitis C virus infection in asymptomatic antiHIV-1 negative pregnant women and their children. Dig Dis Sci 1993;38:2151-5.
39. Roudot-Thoraval F, Deforges L, Girollet PP, et al. Prevalence of hepatitis C virus antibodies (tests ELISA 2 and RIBA 2) in a population of pregnant women in France. Gastroenterol Clin Biol 1992;16:255-9.
40. Caspari G, Gerlich WH, Beyer J, Schmitt H. Age, sex and transaminase dependency of specific and nonspecific results from enzyme immunoassays for antibodies to hepatitis C virus and follow-up of blood donors. Beitr Infusionsther Transfusionsmed 1995;22:208-19.
41. Hennig H, Haase D, Kirchner H. Prevalence of hepatitis C virus in blood donors and comparison of 4 different anti-HCV differentiation tests. Beitr Infusionsther Transfusionsmed 1996;33:231-4.
42. Hugo T, Wust T, Beeser HP. Detection of antibodies to hepatitis C virus in blood donors and their relationship to surrogate markers. Beitr Infusionsther 1992;30:49-52.
43. Knodler B, Kuhnl P, Lubitz B, Roos D, Becks M, Gutensohn K. Hepatitis C virus antibodies in patients and the normal population. Beitr Infusionsther 1992;30:13-6.
44. Barna TK, Ozsvar Z, Szendrenyi V, Gal G. Hepatitis C virus antibody in the serum of blood donors. Orv Hetil 1996;137:507-11.
45. Hejjas M, Medgyesi G, Hajnal A. Reactivity of hepatitis C virus (HCV) antibody among blood donors in Hungary. Orv Hetil 1992;1:21-4.
46. Par A, Kantor I, Barcsay E, et al. Prevalence of antibody to hepatitis C virus in blood donors, high-risk groups and patients with liver diseases in Hungary: a multicentre study using ABBOTT EIA test and a comparison with an ORTHO ELISA test system. Acta Medica Hungarica 1991;48:167-76.
47. Love A, Smaradottir A, Thorsteinsson SB, Stanzeit B, Widell A. Hepatitis C virus genotypes among blood donors and their recipients in Iceland determined by the polymerase chain reaction. Vox Sang 1995;69:18-22.
48. D'Amelio R, Stroffolini T, Matricardi PM, et al. Low prevalence of anti-HCV antibodies among Italian Air Force recruits. Scand J Infect Dis 1995;27:12-4.
49. Chiaramonte M, Stroffolini T, Caporaso N, et al. Hepatitis-C virus infection in Italy: a multicentric sero-epidemiological study (a report from the HCV study group of the Italian Association for the Study of the Liver). Ital J Gastroenterol 1991;23:555-8.
50. Ciuffreda M, Terracina GM, Maisto A, et al. HCV infection and risk of transfusion in the area of Tivoli and its surroundings. Clin Ter 1994;145:41-8.
51. Lai ME, Mazzoleni AP, Farci P, et al. Markers of hepatitis C virus infection in Sardinian blood donors: relationship with alanine aminotransferase levels. J Med Virol 1993;41:282-8.
52. Malaguti M, Capece R, Marciano M, et al. Antibodies to hepatitis C virus (anti-HCV): prevalence in the same geographical area in dialysis patients, staff members, and blood donors. Nephron 1992;61:346.
53. Gessoni G, Manoni F. Prevalence of anti-hepatitis C virus antibodies among teenagers in the Venetian area: a seroepidemiological study. Eur J Med Res 1993;2:79-82.
54. Romano L, Azara A, Chiaramonte M, et al. Low prevalence of anti-HCV antibody among Italian children. Infection 1994;22:350-2.
55. Marranconi F, Fabris P, Stecca C, et al. Prevalence of anti-HCV and risk factors for hepatitis C virus infection in healthy pregnant women. Infection 1994;22:333-7.
56. Puro V, Girardi E, Ippolito G, et al. Prevalence of hepatitis B and C viruses and human immunodeficiency virus infections in women of reproductive age. Br J Obstet Gynaecol 1992;99:598-600.
57. Van-der-Poel CL, Reesink HW, Mauser-Bunschoten EP, et al. Prevalence of anti-HCV antibodies confirmed by recombinant immunoblot in different population subsets in The Netherlands. Vox Sang 1991;61:30-6.
58. Laskus T, Radkowski M, Lupa E, et al. Hepatitis C virus antibody in Poland. Scand J Infect Dis 1991;23:385-6.
59. Lytsar' BN, Skvortsov SV, Poliakova II, Lobanova V, Belov EV. Detection of antibodies to hepatitis C virus in blood donors. Gematologiia Transfuziologiia 1993;38:29-31.
60. Myl'nikov A, Lytsar' BN, Gorbatok LE, Skvortsov SV, Poliakova II, Gorbatiuk V. The detectability of the hepatitis B surface antigen and antibodies to the hepatitis C virus in serviceman blood donors. Voen Med Zh 1994;3:44-5.
61. Sychev Av, Mikhailov MI. The hepatitis C virus infection of Moscow blood donors. Zh Mikrobiol Epidemiol Immunobiol 1993;4:80-3.
62. Esteban JI, Lopez TJ, Genesca J, et al. Evaluation of anti-HCV positive blood donors identified during routine screening. Arch Virol Suppl 1992;4:244-6.
63. Garcia-Bengoechea M, Emparanza JI, Sarriugarte A, et al. Antibodies to hepatitis C virus: a cross-sectional study in patients attending a trauma unit or admitted to hospital for elective surgery. Eur J Gastroenterol Hepatol 1995;7:237-41.
64. Martinez JL, del-Hierro J, Camarero A, Medarde A, Lopez MT, Latasa J. Hepatitis C virus infection in different risk groups and among blood donors. Enferm Infecc Microbiol Clin 1991;9:345-50.
65. Munoz-Gomez R, Garcia-Monzon C, Garcia-Buey L, et al. Hepatitis C virus infection in Spanish volunteer blood donors: HCV RNA analysis and liver disease. Eur J Gastroenterol Hepatol 1996;8:273-7.
66. Salmeron FJ, Palacios A, Perez RM, et al. Epidemiology, serological markers, and hepatic disease of anti-HCV ELISA-2-positive blood donors. Dig Dis Sci 1996;41:1933-8.
67. Suarez A, Rodriguez M, Riestra S, et al. The prevalence of anti-HCV positivity among blood donors in Asturias: a clinical-epidemiologic study. Med Clin Bare 1994;103:606-10.
68. Salleras L, Bruguera M, Vidai J, et al. Seroepidemiology of hepatitis C virus infection in pregnant women in Catalonia. Med Clin (Barc) 1994;103:721-4.
69. Lindholm A. Epidemiology of viral infections in the Swedish blood-donor population. Blood Coagul Fibrinolysis 1994;5:S13-S17.
70. Zufferey C, Lavanchy D, Reiff M, et al. Prevalence of antiHCV (C100-3) antibodies in 20.373 blood donors. Schweiz Med Wochenschr 1992;122:1524-9.
71. Crawford RJ, Gillon J, Yap PL, et al. Prevalence and epidemiological characteristics of hepatitis C in Scottish blood donors. Transfus Med 1994;4:121-4.
72. Garson JA, Clewley JP, Simmonds P, et al. Hepatitis C viraemia in United Kingdom blood donors: a multicentre study. Vox Sang 1992;62:218-23.
73. MacLennan S, Moore MC, Hewitt PE, Nicholas S, Barbara JA. A study of anti-hepatitis C positive blood donors: the first year of screening. Transfus Med 1994;4:125-33.
74. Mutimer DJ, Harrison RF, O'Donnell KB, et al. Hepatitis C virus infection in the asymptomatic British blood donor. J Viral Hepat 1995;2:47-53.
75. Yamaguchi K, Kiyokawa H, Machida J, et al. Seroepidemiology of hepatitis C virus infection in Japan and HCV infection in haemodialysis patients. FEMS Microbiol Rev 1994;14:253-8.
76. Saleh MG, Pereira LM, Tibbs CJ, et al. High prevalence of hepatitis C virus in the normal Libyan population. Trans R Soc Trop Med Hyg 1994;88:292-4.
77. el-Nanawy AA, el-Azzouni OF, Soliman AT, Amer AE, Demian RS. el-Sayed HM. Prevalence of hepatitis-C antibody seropositivity in healthy Egyptian children and four high risk groups. J Trop Pediatr 1995;41:341-3.
78. Mansell CJ, Locarnini SA. Epidemiology of hepatitis C in the East. Semin Liver Dis 1995;15:15-32.
79. Dorozynski A. Half a million French are infected with hepatitis C virus. BMJ 1995;311:1187-8.
80. Bellentani S, Tiribelli C, Saccoccio G, et al. Prevalence of chronic liver disease in the general population of northern Italy: the Dionysos Study. Hepatology 1994;20:1442-9.
81. Alter MJ. Epidemiology of hepatitis C in the West. Semin Liver Dis 1995;15:5-14.
82. Prati D, Capelli C, Silvani C, et al. The incidence and risk factors of community-acquired hepatitis C in a cohort of Italian blood donors. Hepatology 1997;25:702-4.
83. Sasaki F, Tanaka J, Moriya T, et al. Very low incidence rates of community-acquired hepatitis C virus infection in company employees, long-term inpatients, and blood donors in Japan. J Epidemiol 1996;6:198-203.
84. Atrah HI, Hutchinson F, Gough D, Ala FA, Ahmed MM. Hepatitis C virus seroconversion rate in established blood donors. J Med Virol 1995;46:329-33.
85. Aach RD, Stevens CE, Hollinger FB, et al. Hepatitis C virus infection in post-transfusion hepatitis: an analysis with first-and second-generation assays. N Engl J Med 1991;325:1325-9.
86. Tremolada F, Casarin C, Tagger A, et al. Antibody to hepatitis C virus in post-transfusion hepatitis. Ann Intern Med 1991;114:277-81.
87. Zinn C, Dyer O, Dorozynski A, Karcher H, Roberts J. Countries struggle with hepatitis C contamination. BMJ 1995;310:417-8.
88. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study. N Engl J Med 1996;334:1685-90.
89. Pereira BJ, Milford EL, Kirkman RL, Levey AS. Transmission of hepatitis C virus by organ transplantation. N Engl J Med 1991;325:454-60.
90. Conrad EU, Gretch DR, Obermeyer KR, et al. Transmission of the hepatitis-C virus by tissue transplantation. J Bone Joint Surg Am 1995;77:214-24.
91. Shuhart MC, Myerson D, Childs BH, et al. Marrow transplantation from hepatitis C virus seropositive donors: transmission rate and clinical course. Blood 1994;84:3229-35.
92. Tao QM, Wang Y, Wang H, et al. Seroepidemiology of HCV and HBV infection in northern China. Gastroenterologia Japonica 1991;3:156-8.
93. Andrieu J, Barny S, Colardelle P, et al. Prevalence and risk factors of hepatitis C virus infection in a hospitalized population in a gastroenterology unit: role of endoscopic biopsies. Gastroenterol Clin Biol 1995;19:340-5.
94. Bronowicki JP, Venard V, Botte C, et al. Patient-to-patient transmission of hepatitis C virus during colonoscopy. N Engl J Med 1997;337:237-40.
95. Esteban JI, Gomez J, Martell M, et al. Transmission of hepatitis C virus by a cardiac surgeon. N Engl J Med 1996;334:555-60.
96. Marwick C. Hepatitis C is focus of NIH Consensus Panel. JAMA 1997;277:1268-9.
97. Conry CC, VanRaden M, Gibble J, et al. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. N Engl J Med 1996;334:1691-6.
98. Shev S, Widell A, Foberg U, et al. HCV genotypes in Swedish blood donors as correlated to epidemiology, liver disease and hepatitis C virus antibody profile. Infection 1995;23:253-7.
99. Pawlotsky JM, Tsakiris L, Roudot TF, et al. Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C. J Infect Dis 1995;171:1607-10.
100. Seeff LB. Hepatitis C from a needlestick injury. Ann Intern Med 1991:115.
101. Tsude K, Fujiyama S, Sato S, et al. Two cases of accidental transmission of hepatitis C to medical staff. Hepatogastroenterology 1992;39:73-5.
102. Vaglia A, Nicolin R, Puro V, Ippolito G, Bttini C, de Lalla F. Needlestick hepatitis C virus seroconversion in a surgeon. Lancet 1990;336:1315-6.
103. Ridzon R, Gallagher K, Ciesielski C, et al. Simultaneous transmission of human immunodeficiency virus and hepatitis C virus from a needle-stick injury. N Engl J Med 1997;336:919-22.
104. Suzuki E, Kaneko S, Udono T, et al. Absence of nonpercutaneous transmission of hepatitis C virus in a colony of chimpanzees. J Med Virol 1993;39:286-91.
105. Fiore RJ, Potenza D, Monno L, et al. Detection of HCV RNA in serum and seminal fluid from HIV-1 co-infected intravenous drug addicts. J Med Virol 1995;46:364-7.
106. Tang Z, Yang D, Hao L, Tang Z, Huang Y, Wang S. Detection and significance of HCV RNA in saliva, seminal fluid and vaginal discharge in patients with hepatitis C. J Tongji Med Univ 1996;16:11-3.
107. Healey CJ, Smith DB, Walker JL, et al. Acute hepatitis C infection after sexual exposure. Gut 1995;36:148-50.
108. Meisel H, Reip A, Faltus B, et al. Transmission of hepatitis C virus to children and husbands by women infected with contaminated anti-D immunoglobulin. Lancet 1995;345:1209-11.
109. Kao JH, Hwang YT, Chen P J, et al. Transmission of hepatitis C virus between spouses: the important role of exposure duration. Am J Gastroenterol 1996;91:2087-90.
110. Scotto G, Savastano AM, Fazio V, et al. Sexual transmission of hepatitis C virus infection. Eur J Epidemiol 1996;12:241-4.
111. Soto B, Rodrigo L, Garcia-Bengoechea M, et al. Heterosexual transmission of hepatitis C virus and the possible role of coexistent human immunodeficiency virus infection in the index case: a multicentre study of 423 pairings. J Intern Med 1994;236:515-9.
112. Eyster ME, Alter HJ, Aledort LM, Quan S, Hatzakis A, Goedert JJ. Heterosexual co-transmission of hepatitis C virus (HCV) and human immunodeficiency virus (HIV). Ann Intern Med 1991;115:764-8.
113. Shev S, Widell A, Bergstrom T, Hermodsson S, Lindholm A, Norkrans G. Herpes simplex virus-2 may increase susceptibility of the sexual transmission of hepatitis C. Sex Transm Dis 1995;22:210-6.
114. Corona R, Prignano G, Mele A, et al. Heterosexual and homosexual transmission of hepatitis C virus: relation with hepatitis B virus and human immunodeficiency virus type 1. Epidemiol Infect 1991;107:667-72.
115. Weinstock HS, Bolan G, Reingold AL, Polish LB. Hepatitis C viras infection among patients attending a clinic for sexually transmitted diseases. JAMA 1993;269:392-4.
116. Buchbinder SP, Katz MH, Hessol NA, Liu J, O'Malley PM, Alter MJ. Hepatitis C virus infection in sexually active homosexual men. J Infect 1994;29:263-9.
117. Bodsworth NJ, Cunningham P, Kaldor J, Donovan B. Hepatitis C virus infection in a large cohort of homosexually active men: independent associations with HIV-1 infection and injecting drug use but not sexual behaviour. Genitourin Med 1996;72:118-22.
118. Fischler B, Lindh G, Lindgren S, et al. Vertical transmission of hepatitis C virus infection. Scand J Infect Dis 1996;28:353-6.
119. Inoue Y, Takeuchi K, Chou WH, et al. Silent mother-to-child transmission of hepatitis C vims through two generations determined by comparative nucleotide sequence analysis of the viral cDNA. J Infect Dis 1992;166:1425-8.
120. Zanetti AR, Tanzi E, Paccagnini S, et al. Mother-to-infant transmission of hepatitis C virus. Lombardy Study Group on Vertical HCV Transmission. Lancet 1995;345:289-91.
121. Ohto H, Terazawa S, Sasaki N, et al. Transmission of hepatitis C virus from mothers to infants. The Vertical Transmission of Hepatitis C Virus Collaborative Study Group. N Engl J Med 1994;330:744-50.
122. Kurauchi O, Furui T, Itakura A, et al. Studies on transmission of hepatitis C virus from mother-to-child in the perinatal period. Arch Gynecol Obstet 1993;253:121-6.
123. Lin HH, Kao JH, Hsu HY, et al. Absence of infection in breastfed infants born to hepatitis C virus-infected mothers. J Pediatr 1995;126:589-91.
124. Brackmann SA, Gerritzen A, Oldenburg J, Brackmann HH, Schneweis KE. Search for intrafamilial transmission of hepatitis C virus in hemophilia patients. Blood 1993;81:1077-82.
125. Hou CH, Chen WY, Kao JH, et al. Intrafamilial transmission of hepatitis C virus in hemodialysis patients. J Med Virol 1995;45:381-5.
126. Allander T, Gruber A, Naghavi M, et al. Frequent patient-to-patient transmission of hepatitis C virus in a haematology ward. Lancet 1995;345:603-7.
127. de Medina M, Schiff ER. Hepatitis C: diagnostic assays. Semin Liver Dis 1995;15:33-40.
128. McFarlane IG, Smith HM, Johnson PJ, Bray GP, Vergani D, Williams R. Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result? Lancet 1990;335:754-7.
129. Rubin RA, Falestiny M, Malet PF. Chronic hepatitis C: advances in diagnostic testing and therapy. Arch Intern Med 1994;154:387-92.
130. Sherman KE, Creager RL, O'Brien J, Sargent S, Piacentini S, Thieme T. The use of oral fluid for hepatitis C antibody screening. Am J Gastroenterol 1994;89:2025-7.
131. McIntyre PG, Laszlo J, Appleyard K, Ogden GR. Modified enzyme immunoassay to detect hepatitis C virus antibodies in oral fluid. Eur J Clin Microbiol Infect Dis 1996;15:882-4.
132. Okamoto H, Okada S, Sugiyama Y, et al. Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5'-noncoding region. Japanese Journal of Experimental Medicine 1990;60:215-22.
133. Yuki N, Hayashi N, Takehara T, et al. Serum hepatitis C virus RNA levels and liver injury in volunteer blood donors. Am J Gastroenterol 1994;89:1462-6.
134. Schmidt WN, Klinzman D, LaBrecque DR, Macfarlane DE, Stapleton JT. Direct detection of hepatitis C virus (HCV) RNA from whole blood, and comparison with HCV RNA in plasma and peripheral blood mononuclear cells. J Med Virol 1995;47:153-60.
135. Jacob S, Baudy D, Jones E, et al. Comparison of quantitative HCV RNA assays in chronic hepatitis C. Am J Clin Pathol 1997;107:362-7.
136. Farci P, Alter HJ, Wong D, et al. A long-term study of hepatitis C virus replication in non-A, non-B hepatitis. N Engl J Med 1991;325:98-104.
137. Colombo M. The natural history of hepatitis C. Bailliere's Clin Gastroenterol 1996;10:275-88.
138. Yanagi M, Kaneko S, Unoura M, et al. Hepatitis C virus in fulminant hepatic failure. N Engl J Med 1991;324:1895-6.
139. Wright TL, Hsu H, Donegan E, et al. Hepatitis C virus not found in fulminant non-A, non-B hepatitis. Ann Intern Med 1991;115:111-2.
140. Liang TJ, Jeffers L, Reddy RK, et al. Fulminant or subfulminant non-A. non-B viral hepatitis: the role of hepatitis C and E viruses. Gastroenterology 1993;104:556-62.
141. Prieto M, Olaso V, Verdu C, et al. Does the healthy hepatitis C virus carrier state really exist?: an analysis using polymerase chain reaction. Hepatology 1995;22:413-7.
142. Dusheiko GM, Khakoo S, Soni P, Grellier L. A rational approach to the management of hepatitis C infection. BMJ 1996;312:357-64.
143. Tong MJ, el Farsa NS, Reikes AR, Co RL. Clinical outcomes after transfusion-associated hepatitis C. N Engl J Med 1995;332:1463-6.
144. Muller R. The natural history of hepatitis C: clinical experiences. J Hepatol 1996;24 Suppl 2:52-4.
145. Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C: the OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997;349:825-32.
146. Feray C, Gigou M, Samuel D, et al. Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation. Gastroenterology 1995;108:1088-96.
147. Chan TM, Wu PC, Lok AS, Lai CL, Cheng IK. Clinicopathological features of hepatitis C virus antibody negative fatal chronic hepatitis C after renal transplantation. Nephron 1995;71:213-7.
148. Eyster ME, Diamondstone LS, Lien JM, Ehmann WC, Quan S, Goedert JJ. Natural history of hepatitis C virus infection in multitransfused hemophiliacs: effect of coinfection with human immunodeficiency virus. The Multicenter Hemophilia Cohort Study. J Acquir Immune Defic Syndr 1993;6:602-10.
149. Kiyosawa K, Sodeyama T, Tanaka E, et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990;12:671-5.
150. Okuda K, Liver cancer. In: Zuckerman AJ, Thomas HC, editors. Viral hepatitis: scientific basis and clinical management. London: Churchill Livingstone; 1996. p. 269-81.
151. Kaklamani E, Trichopoulos D, Tzonou A, et al. Hepatitis B and C viruses and their interaction in the origin of hepatocellular carcinoma. JAMA 1991;265:1974-6.
152. Chiba T, Matsuzaki Y, Abei M, et al. Multivariate analysis of risk factors for hepatocellular carcinoma in patients with hepatitis C virus-related liver cirrhosis. J Gastroenterol 1996;31:552-8.
153. Miyakawa H, Izumi N, Marumo F, Sato C. Roles of alcohol, hepatitis virus infection, and gender in the development of hepatocellular carcinoma in patients with liver cirrhosis. Alcohol Clin Exp Res 1996;20 Suppl 9:297A-300A.
154. Tsutsumi M, Ishizaki M, Takada A. Relative risk for the development of hepatocellular carcinoma in alcoholic patients with cirrhosis: a multiple logistic-regression coefficient analysis. Alcohol Clin Exp Res 1996;20:758-62.
155. Zein NN, Poterucha JJ, Gross JJ, et al. Increased risk of hepatocellular carcinoma in patients infected with hepatitis C genotype Ib. Am J Gastroenterol 1996;91:2560-2.
156. Bruno S, Silini E, Crosignani A, et al. Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a prospective study. Hepatology 1997;25:754-8.
157. Johnson PJ. The epidemiology of hepatocellular carcinoma. Eur J Gastroenterol Hepatol 1996;8:845-9.
158. De Mitri M, Poussin K, Baccarini P, et al. HCV-associated liver cancer without cirrhosis. Lancet 1995;345:413-5.
159. Seeff LB, Buskell BZ, Wright EC, et al. Long-term mortality after transfusion-associated non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study Group. N Engl J Med 1992;327:1906-11.
160. Tremolada F, Casarin C, Alberti A, et al. Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis. J Hepatol 1992;16:273-81.
161. Koff RS, Dienstag JL. Extrahepatic manifestations of hepatitis C and the association with alcoholic liver disease. Semin Liver Dis 1995;15:101-9.
162. Hadziyannis SJ. The spectrum of extrahepatic manifestations in hepatitis C infection. J Viral Hepat 1997;4:9-28.
163. Gumber SC, Chopra S. Hepatitis C: a multifaceted disease: review of extrahepatic manifestations. Ann Intern Med 1995;123:615-20.
164. Ferri C, Monti M, La CL, et al. Hepatitis C virus infection in non-Hodgkin's B-cell lymphoma complicating mixed cryoglobulinaemia. Eur J Clin Invest 1994;24:781-4.
165. Johnson RJ, Gretch DR, Yamabe H, et al. Membranoproliferative glomerulonephritis associated with hepatitis C virus infection. N Engl J Med 1993;328:465-70.
166. Cribier B, Petiau P, Keller F, et al. Porphyria cutanea tarda and hepatitis C viral infection: a clinical and virologie study. Arch Dermatol 1995;131:801-4.
167. Pawlotsky JM, Dhumeaux D, Bagot M. Hepatitis C virus in dermatology: a review. Arch Dermatol 1995;131:1185-93.
168. Grimbert S, Valensi P, Levy MC, et al. High prevalence of diabetes mellitus in patients with chronic hepatitis C: a case-control study. Gastroenterol Clin Biol 1996;20:544-8.
169. Allison ME, Wreghitt T, Palmer CR, Alexander GJ. Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population. J Hepatol 1994;21:1135-9.
170. Simo R, Hernandez C, Genesca J, Jardi R, Mesa J. High prevalence of hepatitis C virus infection in diabetic patients. Diabetes Care 1996;19:998-1000.
171. Clifford BD, Donahue D, Smith L, et al. High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C. Hepatology 1995;21:613-9.
172. Bellary S, Schiano T, Hartman G, Black M. Chronic hepatitis with combined features of autoimmune chronic hepatitis and chronic hepatitis C: favorable response to prednisone and azathioprine. Ann Intern Med 1995;123:32-4.
173. Wiranowska SM, Stewart Wd. Determination of human leukocyte populations involved in production of interferons alpha and gamma. J Interferon Res 1981;1:233-44.
174. Harper DR. Viral interactions with the immune system. In: Harper DR. Molecular virology. Oxford: BIOS Scientific Publisher; 1994. p. 51-74.
175. Davis GL, Hoofnagle JH. Interferon in viral hepatitis: role in pathogenesis and treatment. Hepatology 1986;6:1038-41.
176. Hoofnagle JH, di Bisceglie AM. The treatment of chronic viral hepatitis. N Engl J Med 1997;336:347-56.
177. Sanchez-Tapias JM, Rodes J. Interferon in chronic hepatitis C. Lancet 1995;346(suppl):11.
178. Orito E, Mizokami M, Suzuki K, et al. Loss of serum HCV RNA at week 4 of interferon-alpha therapy is associated with more favorable long-term response in patients with chronic hepatitis C. J Med Virol 1995;46:109-15.
179. Saracco G, Rizzetto M. Predictors of response to Interferon therapy. Dig Dis Sci 1996;41:115s-120s.
180. Camma C, Almasio P, Craxi A. Interferon as treatment for acute hepatitis C: a meta-analysis. Dig Dis Sci 1996;41:1248-55.
181. Idilman R, De Maria N, Colantoni A, Dokmeci A, Van Thiel DH. Interferon treatment of cirrhotic patients with chronic hepatitis C. J Viral Hepat 1997;4:81-91.
182. Mazzella G, Accogli E, Sottili S, et al. Alpha interferon treatment may prevent hepatocellular carcinoma in HCV-related liver cirrhosis. J Hepatol 1996;24:141-7.
183. Nishiguchi S, Kuroki T, Nakatani S, et al. Randomised trial of effects of interferon-alpha on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet 1995;346:1051-5.
184. Bailly F, Mattei A, SiAhmed SN, Trepo C. Uncommon side-effects of interferon. J Viral Hepat 1997;4 Suppl 1:89-94.
185. Schalm SW, Brouwer JT, Chemello L, et al. Interferonribavirin combination therapy for chronic hepatitis C. Dig Dis Sci 1996;41 Suppl 41:1315-45.
186. Reichard O, Norkrans G, Fryden A, Braconier JH, Sönnerborg A. Weiland O. Randomised, double blind, placebo-controlled trial of interferon alpha-2b with and without ribavirin for chronic hepatitis C. Lancet 1998;351:83-7.
187. Lodi G, Porter SR. Occupational risk of hepatitis C virus infection to dental health care staff: an update. Dental Update 1996;23:255-8.
188. Sepkowitz KA. Occupationally acquired infections in health care workers, part II. Ann Intern Med 1996;125:917-28.
189. Siew C, Gruninger SE, Miaw CL, Neidle EA. Percutaneous injuries in practicing dentists: a prospective study using a 20-day diary. J Am Dent Assoc 1995;126:1227-34.
190. Felix DH, Bird AG, Anderson HG, Gore SM, Brettle RP, Wray D. Recent nonsterile inoculation injuries to dental professionals in the Lothian region of Scotland. Br Dent J 1994;176:180-4.
191. Piazza M, Borgia G, Picciotto L, Nappa S, Cicciarello S, Orlando R. Detection of hepatitis C virus-RNA by polymerase chain reaction in dental surgeries. J Med Virol 1995;45:40-2.
192. Fong TL, Charboneau F, Valinluck B, Govindarajan S. The stability of serum hepatitis C viral RNA in various handling and storage conditions. Arch Pathol Lab Med 1993;117:150-1.
193. Hsu HH, Wright TL, Luba D, et al. Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction. Hepatology 1991;14:763-7.
194. Couzigou P, Richard L, Dumas F, Schouler L, Fleury H. Detection of HCV-RNA in saliva of patients with chronic hepatitis C. Gut 1993;34:S59-S60.
195. Wang JT, Wang TH, Lin JT, Sheu JC, Lin SM, Chen DS. Hepatitis C virus RNA in saliva of patients with post-transfusion hepatitis C infection. Lancet 1991;337:48.
196. Roy KM, Bagg J, Bird GL, et al. Serological and salivary markers compared with biochemical markers for monitoring interferon treatment for hepatitis C virus infection. J Med Virol 1995;47:429-34.
197. Sugimura H, Yamamoto H, Watabiki H, et al. Correlation of detectability of hepatitis C virus genome in saliva of elderly Japanese symptomatic HCV carriers with their hepatic function. Infection 1995;23:258-62.
198. Chen M, Yun ZB, Sailberg M, et al. Detection of hepatitis C virus RNA in the cell fraction of saliva before and after oral surgery. J Med Virol 1995;45:223-6.
199. Abe K, Inchauspe G. Transmission of hepatitis C by saliva. Lancet 1991;337:248.
200. Dusheiko GM, Smith M, Scheuer PJ. Hepatitis C virus transmitted by human bite. Lancet 1990;336:503-4.
201. Figueiredo JF, Borges AS, Martinez R, et al. Transmission of hepatitis C virus but not human immunodeficiency virus type 1 by a human bite. Clin Infect Dis 1994;19:546-7.
202. Schiff ER, De Medina MD, Hill MA, Johnson G. Prevalence of anti-HCV in the VA dental environment from 1979-1981. Hepatology 1990;12:849.
203. Klein RS, Freeman K, Taylor PE, Stevens CE. Occupational risk for hepatitis C virus infection among New York City dentists. Lancet 1991;338:1539-42.
204. Herbert AM, Walker DM, Davies KJ, Bagg J. Occupationally acquired hepatitis C virus infection. Lancet 1992;339:305.
205. Kuo MY, Hahn LJ, Hong CY, Kao JH, Chen DS. Low prevalence of hepatitis C virus infection among dentists in Taiwan. J Med Virol 1993;40:10-3.
206. Gerberding JL. Incidence and prevalence of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and cytomegalovirus among health care personnel at risk for blood exposure: final report from a longitudinal study. J Infect Dis 1994;170:1410-7.
207. Thomas DL, Gruninger SE, Slew C, Joy ED, Quinn TC. Occupational risk of hepatitis C infections among general dentists and oral surgeons in North America. Am J Med 1996;100:41-5.
208. Olubuyide IO, Ola SO, Aliyu B, et al. Hepatitis B and C in doctors and dentists in Nigeria. QJM 1997;90:417-22.
209. Lodi G, Porter SR, Teo CG, Scully C. Prevalence of HCV-infection in health care workers of a London Dental Hospital. Br Dent J 1997;183:329-32.
210. Goodrick MJ, Gray SF, Rouse AM, Waters AJ, Anderson NA. Hepatitis C (HCV)-positive blood donors in south-west England: a case control study. Transfus Med 1994;4:113-9.
211. Neal KR, Jones DA, Killey D, James V. Risk factors for hepatitis C virus infection: a case-control study of blood donors in the Trent Region (UK). Epidemiol Infect 1994;112:595-601.
212. Recommendations for follow-up of health-care workers after occupational exposure to hepatitis C virus. MMWR 1997;46:603-6.
213. Chen TZ, Wu JC, Yen FS, et al. Injection with nondisposable needles as an important route for transmission of acute community-acquired hepatitis C virus infection in Taiwan. J Med Virol 1995;46:247-51.
214. Mele A, Sagliocca L, Manzillo G, et al. Risk factors for acute non-A, non-B hepatitis and their relationship to antibodies for hepatitis C virus: a case-control study. Am J Public Health 1994;84:1640-3.
215. Mokni M, Rybojad M, Puppin D Jr, et al. Lichen planus and hepatitis C virus. J Am Acad Dermatol 1991;24:792.
216. Cribier B, Gamier C, Laustriat D, Heid E. Lichen planus and hepatitis C virus infection: an epidemiologic study. J Am Acad Dermatol 1994;31:1070-2.
217. Dupin N, Chosidow O, Lunel F, Fretz C, Szpirglas H, Frances C. Oral lichen planus and hepatitis C virus infection: a fortuitous association? Arch Dermatol 1997;133:1052-3.
218. Ingafou M, Porter SR, Scully C, Teo GC. No evidence of HCV infection or liver disease in English patients with oral lichen planus. Int J Oral Maxillofac Surg 1998;27:65-6.
219. Mignogna MD, Lo Muzio L, Mignogna RE, Carbone R, Bucci E. Preliminary report on the association between oral lichen planus and HCV-antibody positivity in Southern Italy: a clinical evaluation of 178 cases. J Oral Pathol Med 1996;25:289.
220. Nagao Y, Sata M, Tanikawa K, Itoh K, Kameyama T. Lichen planus and hepatitis C virus in the northern Kyushu region of Japan. Eur J Clin invest 1995;25:910-4.
221. Sanchez-Perez J, De-Castro M, Buezo GF, Fernandez-Herrera J, Borque MJ, Garcia-Diez A. Lichen planus and hepatitis C virus: prevalence and clinical presentation of patients with lichen planus and hepatitis C virus infection. Br J Dermatol 1996;134:715-9.
222. Carrozzo M, Gandolfo S, Carbone M, et al. Hepatitis C virus infection in Italian patients with oral lichen planus: a prospective case-control study. J Oral Pathol Med 1996;25:527-33.
223. Bellman B, Reddy RK, Falanga V. Lichen planus associated with hepatitis C. Lancet 1995;346:1234.
224. Imhof M, Popal H, Lee JH, Zeuzem S, Milradt R. Prevalence of hepatitis C virus antibodies and evaluation of hepatitis C virus genotypes in patients with lichen planus. Dermatology 1997;195:1-5.
225. Pawlotsky JM, Ben-Yahia M, Andre C, et al. Immunological disorders in C virus chronic active hepatitis: a prospective case-control study. Hepatology 1994;19:841-8.
226. Sata M, Nagao Y, Suzuki H, Ide T, Itoh K, Tanikawa K. Oral lichen planus and hepatitis C virus infection. Gastroenterology 1996;110:A1312.
227. Porter SR, Lodi G, Chandler K, Kumar N. Development of squamous cell carcinoma in hepatitis C virus associated lichen planus. Oral Oncol Eur J Cancer 1997;336:58-9.
228. Carrozzo M, Carbone M, Gandolfo S, Valente G, Colombatto P, Ghisetti V. An atypical verrucous carcinoma of the tongue arising in a patient with oral lichen planus associated with hepatitis C virus infection. Oral Oncol Eur J Cancer 1997;33B:220-5.
229. Nagao Y, Sata M, Itoh K, Tanikawa K, Kameyama T. Quantitative analysis of HCV RNA and genotype in patients with chronic hepatitis C accompanied by oral lichen planus. Eur J Clin Invest 1996;26:495-8.
230. Lodi G, Carrozzo M, Hallett R, et al. HCV serotypes in Italian patients with HCV-related oral lichen planus. J Oral Pathol Med 1997;26:381-4.
231. Pawlotsky JM, Benchiki H, Pellet C, et al. Lichen planus and hepatitis C virus (HCV)-related chronic hepatitis: evaluation of HCV genotypes. Br J Dermatol 1995;133:666-7.
232. Nagao Y, Sata M, Noguchi S, et al. GB virus infection in patients with oral cancer and oral lichen planus. J Oral Pathol Med 1997;26:138-41.
233. Lodi G, Porter SR. Hepatitis C virus infection and lichen planus: a short review. Oral Dis 1997;3:77-81.
234. Rebora A. Hepatitis viruses and lichen planus. Arch Dermatol 1994;130:1328-9.
235. Lodi G, Olsen I, Piattelli A, D'Amico E, Artese L, Porter SR. Antibodies to epithelial components in oral lichen planus (OLP) associated with hepatitis C virus (HCV) infection. J Oral Pathol Med 1997;26:36-9.
236. Parodi A, Cardo PP. Patients with erosive lichen planus may have antibodies directed to a nuclear antigen of epithelial cells: a study on the antigen nature. J Invest Dermatol 1989;94:689-93.
237. Doutre MS, Couzigou P, Beylot BM, Beylot C, Quinton A. Lichen planus and hepatitis C: heterogeneity in the course of 6 cases treated with interferon alpha. Gastroenterol Clin Biol 1996;20:709-10.
238. Lapidoth M, Arber N, Ben-Amitai D, Hagler J. Successful interferon treatment for lichen planus associated with chronic active hepatitis due to hepatitis C virus infection. Acta Derm Venereol 1997;77:171-2.
239. Boccia S, Gamberini S, Dalla-Libera M, Strumia R, Venturini D. Lichen planus and interferon therapy for hepatitis C. Gastroenterology 1993;105:1921-2.
240. Revenga-Arranz F, de-Argila-Fernandez-Duran D, Rivera-Diaz R, Iglesias-Diez L. Lichen planus and hepatitis C virus infection: study of 6 cases. Rev Clin Esp 1995;195:550-2.
241. Dupin N, Chosidow O, Frances C, et al. Lichen planus after alpha-interferon therapy for chronic hepatitis C. Eur J Dermatol 1994;4:535-6.
242. Mariette X. Sjogren's syndrome and virus. Ann Med Interne (Paris) 1995;146:243-6.
243. Haddad J, Deny P, Munz-Gotheil C, et al. Lymphocytic sialadenitis of Sjogren's syndrome associated with chronic hepatitis C virus liver disease. Lancet 1992;339:321-3.
244. Guisset M, Klotz F, Debonne JM, Vitte S. Sicca syndrome and low-grade chronic viral hepatitis C: apropos of a series of 50 cases. Rev Med Interne 1993;14:1006.
245. Mariette X, Zerbib M, Jaccard A, Schenmetzler C, Danon F, Clauvel JP. Hepatitis C virus and Sjogren's syndrome. Arthritis Rheum 1993;36:280-1.
246. Poet JL, Torolli-Serabian I, Gamier PP. Chronic hepatitis C and Sjogren's syndrome. J Rheumatol 1994;21:1376-7.
247. Wattiaux MJ, Jouan-Flahault C, Youinou P, et al. Association of Gougerot-Sjogren syndrome and viral hepatitis C: apropos of 6 cases. Ann Med Interne (Paris) 1995;146:247-50.
248. Boscagli A, Hatron PY, Canva-Delcambre V, et al. Sicca syndrome and hepatitis C virus infection: a Gougerot-Sjogren pseudo-syndrome? Rev Med Interne 1996;17:375-80.
249. Jorgensen C, Legouffe MC, Perney P, et al. Sicca syndrome associated with hepatitis C virus infection. Arthritis Rheum 1996;39:1166-71.
250. Aceti A, Taliani G, Sorice M, Amendolea MA. HCV and Sjogren's syndrome. Lancet 1992;339:1425-6.
251. Pirisi M, Scott C, Fabris C, et al. Mild sialadenitis: a common finding in patients with hepatitis C virus infection. Scand J Gastroenterol 1994;29:940-2.
252. Masaki N, Hayashi S. Autoimmune liver disease complicating Sjogren's syndrome. Nippon Rinsho 1995;53:2530-5.
253. Rodriguez-Cuartero A, Garcia-Vera E, Gomez-Cerro A. Hepatitis C virus and Sjogren's syndrome. Infection 1994;22:415-6.
254. Garcia CM, Ramos M, Cervera R, et al. Hepatitis C virus infection in "primary" Sjogren's syndrome: prevalence and clinical significance in a series of 90 patients. Ann Rheum Dis 1997;56:173-5.
255. Porter SR, Scully C, Lodi G, Teo CG. Lack of association between hepatitis C virus and Sjogren's syndrome. Oral Dis 1996;2:183-4.
256. King PD, McMurray RW, Becherer PR. Sjogren's syndrome without mixed cryoglobulinemia is not associated with hepatitis C virus infection. Am J Gastroenterol 1994;89:1047-50.
257. Marrone A, Di-Bisceglie AM, Fox P. Alasence of hepatitis C viral infection among patients with primary Sjogren's syndrome. J Hepatol 1995;22:599.
258. Durand JM, Lefevre P, Kaplanski G, et al. Sjogren's syndrome and hepatitis C virus infection. Clin Rheumatol 1995;14:570-1.
259. Feucht HH, Polywka S, Zollner B, Laufs R. Greater amount of HCV-RNA in tears compared to blood. Microbiol Immunol 1994;38:157-8.
260. Nagao Y, Sata M, Tanikawa K, Itoh K, Kameyama T. High prevalence of hepatitis C virus antibody and RNA in patients with oral cancer. J Oral Pathol Med 1995;24:354-60.
261. Jaber M, Bain L, Porter SR. Lack of association between hepatitis C virus infection and oral epithelial dysplasia. Int J Oral Maxillofac Surg. In press.
262. Nagao Y, Sata M, Fukuizumi K, Harada H, Kameyama T. Oral cancer and hepatitis C virus (HCV): can HCV alone cause oral cancer?-a case report. Kurume Med J 1996;43:97-100.
263. Munke H, Stockmann F, Ramadori G. Possible association between Behcet's syndrome and chronic hepatitis C virus infection. N Engl J Med 1995;332:400-1.
264. Hamuryudan V, Moral F, Yurdakul S, et al. Systemic Interferon alpha 2b treatment in Behçet's syndrome. J Rheumatol 1994;21:1098-100.
265. Oguz A, Sametoglu F, Erdogan S. More on hepatitis C and Behçet's syndrome. N Engl J Med 1995;333:322-3.
266. Antinori S, Esposito R, Aliprandi CA, Tadini G. Erythema multiforme and hepatitis C. Lancet 1991;337.
267. Esteban R. Managing patients on interferon therapy. Dig Dis Sci 1996;41:121s-125s.
268. Wisnom CJ, Kelly M. Medical/dental management of a chronic hepatitis C patient: a case report. Oral Surg Oral Med Oral Pathol 1993;75:786-90.
269. Reddi S, Garg AK. Patients with chronic hepatitis - potential risks when undergoing dental surgery: review and case report. Special Care Dentist 1994;14:241-5
270. Scully C, Cawson RA. Medical problems in dentistry. 4th ed. Oxford: Wright; 1998.