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Volumn 80, Issue 1, 1996, Pages 252-260

Chronic inhaled nitric oxide: Effects on pulmonary vascular endothelial function and pathology in rats

Author keywords

chronic hypoxia; endothelium derived relaxing factor; nitric oxide synthase; normoxia; pulmonary hypertension; vascular remodeling

Indexed keywords

BRADYKININ; N(G) NITROARGININE METHYL ESTER; OXYGEN;

EID: 0030041523     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.80.1.252     Document Type: Article
Times cited : (74)

References (38)
  • 1
    • 0025963441 scopus 로고
    • Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia
    • Adnot, S., E. Raffestin, S. Eddahibi, P. Braquet, and P. Chabrier. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87: 155-162, 1991.
    • (1991) J. Clin. Invest. , vol.87 , pp. 155-162
    • Adnot, S.1    Raffestin, E.2    Eddahibi, S.3    Braquet, P.4    Chabrier, P.5
  • 2
    • 0025736138 scopus 로고
    • Localization of the sites of pulmonary vasomotion by use of arterial and venous occlusion
    • Audi, S. H., C. A. Dawson, D. A. Rickaby, and J. H. Linehan. Localization of the sites of pulmonary vasomotion by use of arterial and venous occlusion. J. Appl. Physiol. 70: 2126-2136, 1991.
    • (1991) J. Appl. Physiol. , vol.70 , pp. 2126-2136
    • Audi, S.H.1    Dawson, C.A.2    Rickaby, D.A.3    Linehan, J.H.4
  • 3
    • 0020614041 scopus 로고
    • Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover
    • Axelsson, K. L., and R. G. G. Andersson. Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover. Eur. J. Pharmacol. 88: 71-79, 1983.
    • (1983) Eur. J. Pharmacol. , vol.88 , pp. 71-79
    • Axelsson, K.L.1    Andersson, R.G.G.2
  • 4
    • 0027416774 scopus 로고
    • Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats
    • Barer, G., C. Emery, A. Stewart, D. Bee, and P. Howard. Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats. J. Physiol. Lond. 463: 1-16, 1993.
    • (1993) J. Physiol. Lond. , vol.463 , pp. 1-16
    • Barer, G.1    Emery, C.2    Stewart, A.3    Bee, D.4    Howard, P.5
  • 5
    • 0027295446 scopus 로고
    • An improved mathematical approach for the assessment of the medial thickness of pulmonary arteries
    • Earth, P. J., C. Kimpel, S. Roy, and U. Wagner. An improved mathematical approach for the assessment of the medial thickness of pulmonary arteries. Pathol. Res. Pract. 189: 567-576, 1993.
    • (1993) Pathol. Res. Pract. , vol.189 , pp. 567-576
    • Earth, P.J.1    Kimpel, C.2    Roy, S.3    Wagner, U.4
  • 6
    • 0027436619 scopus 로고
    • Negative feedback regulation of endothelial cell function by nitric oxide
    • Buga, G. M., J. M. Griscavage, N. E. Rogers, and L. J. Ignarro. Negative feedback regulation of endothelial cell function by nitric oxide. Circ. Res. 73: 808-812, 1993.
    • (1993) Circ. Res. , vol.73 , pp. 808-812
    • Buga, G.M.1    Griscavage, J.M.2    Rogers, N.E.3    Ignarro, L.J.4
  • 7
    • 0025760972 scopus 로고
    • Chronic exposure of exogenous nitric oxide may suppress its endogenous release and efficacy
    • Bult, H., G. R. Y. De Meyer, F. H. Jordaens, and A. G. Herman. Chronic exposure of exogenous nitric oxide may suppress its endogenous release and efficacy. Cardiovasc. Pharmacol. 17, Suppl. 3: S79-S82, 1991.
    • (1991) Cardiovasc. Pharmacol. , vol.17 , Issue.3 SUPPL.
    • Bult, H.1    De Meyer, G.R.Y.2    Jordaens, F.H.3    Herman, A.G.4
  • 9
    • 0027311051 scopus 로고
    • Impairment of pulmonary-artery endothelium-dependent relaxation in chronic obstructive lung disease is not due to dysfunction of endothelial cell membrane receptors nor to L-arginine deficiency
    • Dinh-Xuan, A. T., J. Pepke-Zaba, A. Y. Butt, G. Cremona, and T. W. Hlgenbottam. Impairment of pulmonary-artery endothelium-dependent relaxation in chronic obstructive lung disease is not due to dysfunction of endothelial cell membrane receptors nor to L-arginine deficiency. Br. J. Pharmacol. 109: 587-591, 1993.
    • (1993) Br. J. Pharmacol. , vol.109 , pp. 587-591
    • Dinh-Xuan, A.T.1    Pepke-Zaba, J.2    Butt, A.Y.3    Cremona, G.4    Hlgenbottam, T.W.5
  • 10
    • 0027418979 scopus 로고
    • Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation
    • Frostell, C. G., H. Blomqvist, G. Hedenstierna, J. Lundberg, and W. M. Zapol. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology 78: 427-435, 1993.
    • (1993) Anesthesiology , vol.78 , pp. 427-435
    • Frostell, C.G.1    Blomqvist, H.2    Hedenstierna, G.3    Lundberg, J.4    Zapol, W.M.5
  • 11
    • 0025910315 scopus 로고
    • Inhaled nitric oxide: A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction
    • Frostell, C., M. D. Fratacci, J. C. Wain, R. Jones, and W. M. Zapol. Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 83: 2038-2047, 1991.
    • (1991) Circulation , vol.83 , pp. 2038-2047
    • Frostell, C.1    Fratacci, M.D.2    Wain, J.C.3    Jones, R.4    Zapol, W.M.5
  • 12
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg, U. C., and A. Hassid. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 83: 1774-1777, 1989.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 13
    • 0027724030 scopus 로고
    • Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome
    • Gerlach, H., D. Pappert, K. Lewandowski, R. Rossaint, and K. J. Falke. Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med. 19: 443-449, 1993.
    • (1993) Intensive Care Med. , vol.19 , pp. 443-449
    • Gerlach, H.1    Pappert, D.2    Lewandowski, K.3    Rossaint, R.4    Falke, K.J.5
  • 14
    • 0027451371 scopus 로고
    • Chronic EDRF inhibition and hypoxia: Effects on pulmonary circulation and systemic blood pressure
    • Hampl, V., S. L. Archer, D. P. Nelson, and E. K. Weir. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure. J. Appl. Physiol. 75: 1748-1757, 1993.
    • (1993) J. Appl. Physiol. , vol.75 , pp. 1748-1757
    • Hampl, V.1    Archer, S.L.2    Nelson, D.P.3    Weir, E.K.4
  • 15
    • 0028095289 scopus 로고
    • Nitric oxide selectively amplifies FGF2-induced mitogenesis in primary rat aortic smooth muscle cells
    • Heart Circ. Physiol. 36
    • Hassid, A., H. Arabshahi, T. Bourcier, G. S. Dhaunsi, and C. Matthews. Nitric oxide selectively amplifies FGF2-induced mitogenesis in primary rat aortic smooth muscle cells. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1040-H1048, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Hassid, A.1    Arabshahi, H.2    Bourcier, T.3    Dhaunsi, G.S.4    Matthews, C.5
  • 16
    • 0026567472 scopus 로고
    • Partial reversal of hypoxic pulmonary hypertension by heparin
    • Hassoun, P. M., B. T. Thompson, and C. A. Hales. Partial reversal of hypoxic pulmonary hypertension by heparin. Am. Rev. Respir. Dis. 145: 193-196, 1992.
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 193-196
    • Hassoun, P.M.1    Thompson, B.T.2    Hales, C.A.3
  • 17
    • 0018348875 scopus 로고
    • Effect of exposure to 43 ppm nitric oxide and 3.6 ppm nitrogen dioxide on rabbit lung
    • Hugod, C. Effect of exposure to 43 ppm nitric oxide and 3.6 ppm nitrogen dioxide on rabbit lung. Int. Arch. Occup. Environ. Health 42: 159-167, 1979.
    • (1979) Int. Arch. Occup. Environ. Health , vol.42 , pp. 159-167
    • Hugod, C.1
  • 18
    • 0028211799 scopus 로고
    • Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats
    • Isaacson, T. C., V. Hampl, E. K. Weir, D. P. Nelson, and S. L. Archer. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J. Appl. Physiol. 76: 933-940, 1994.
    • (1994) J. Appl. Physiol. , vol.76 , pp. 933-940
    • Isaacson, T.C.1    Hampl, V.2    Weir, E.K.3    Nelson, D.P.4    Archer, S.L.5
  • 19
    • 0027260899 scopus 로고
    • Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia
    • Kourembanas, S., L. P. McQuillan, G. K. Leung, and D. V. Faller. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. J. Clin. Invest. 92: 99-104, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 99-104
    • Kourembanas, S.1    McQuillan, L.P.2    Leung, G.K.3    Faller, D.V.4
  • 20
    • 0028069803 scopus 로고
    • Continuous inhalation of nitric oxide protects against development of pulmonary hypertension in chronically hypoxic rats
    • Kouyoumdjian, C., S. Adnot, M. Levame, S. Eddahibi, H. Bousbaa, and B. Raffestin. Continuous inhalation of nitric oxide protects against development of pulmonary hypertension in chronically hypoxic rats. J. Clin. Invest. 94: 578-584, 1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 578-584
    • Kouyoumdjian, C.1    Adnot, S.2    Levame, M.3    Eddahibi, S.4    Bousbaa, H.5    Raffestin, B.6
  • 21
    • 0028919174 scopus 로고
    • Microvascular responses to inhibition of nitric oxide production: Role of active oxidants
    • Kurose, I., R. Wolf, M. B. Grisham, T. Y. Aw, R. D. Specian, and D. N. Granger. Microvascular responses to inhibition of nitric oxide production: role of active oxidants. Circ. Res. 76: 30-39, 1995.
    • (1995) Circ. Res. , vol.76 , pp. 30-39
    • Kurose, I.1    Wolf, R.2    Grisham, M.B.3    Aw, T.Y.4    Specian, R.D.5    Granger, D.N.6
  • 22
    • 0026624753 scopus 로고
    • Role of nitric oxide in modulating permeability of hamster cheek pouch in response to adenosine 5′-diphosphate and bradykinin
    • Mayhan, W. G. Role of nitric oxide in modulating permeability of hamster cheek pouch in response to adenosine 5′-diphosphate and bradykinin. Inflammation 16: 295-305, 1992.
    • (1992) Inflammation , vol.16 , pp. 295-305
    • Mayhan, W.G.1
  • 23
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada, S., and A. Higgs. The L-arginine-nitric oxide pathway. N. Engl J. Med. 329: 2002-2012, 1993.
    • (1993) N. Engl J. Med. , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 24
    • 0027315757 scopus 로고
    • EDRF suppresses an unidentified vasoconstrictor mechanism in hypertensive rat lungs
    • Lung Cell. Mol. Physiol. 8
    • Oka, M., K. Hasunuma, S. A. Webb, T. J. Stelzner, D. M. Rodman, and I. F. McMurtry. EDRF suppresses an unidentified vasoconstrictor mechanism in hypertensive rat lungs. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L587-L597, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Oka, M.1    Hasunuma, K.2    Webb, S.A.3    Stelzner, T.J.4    Rodman, D.M.5    McMurtry, I.F.6
  • 25
    • 0026758383 scopus 로고
    • PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats
    • Ono, S., J. Y. Westcott, and N. F. Voelkel. PAF antagonists inhibit pulmonary vascular remodeling induced by hypobaric hypoxia in rats. J. Appl. Physiol. 73: 1084-1092, 1992.
    • (1992) J. Appl. Physiol. , vol.73 , pp. 1084-1092
    • Ono, S.1    Westcott, J.Y.2    Voelkel, N.F.3
  • 26
    • 0024244829 scopus 로고
    • Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension
    • Orton, E. C., J. T. Reeves, and K. R. Stenmark. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension. J. Appl. Physiol. 65: 2459-2467, 1988.
    • (1988) J. Appl. Physiol. , vol.65 , pp. 2459-2467
    • Orton, E.C.1    Reeves, J.T.2    Stenmark, K.R.3
  • 27
    • 0027537605 scopus 로고
    • Inhaled nitric oxide reverses hypoxic pulmonary vasoconstriction without impairing gas exchange
    • Pison, U., F. A. López, C. F. Heidelmeyer, R. Rossaint, and K. J. Falke. Inhaled nitric oxide reverses hypoxic pulmonary vasoconstriction without impairing gas exchange. J. Appl. Physiol. 74: 1287-1292, 1993.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 1287-1292
    • Pison, U.1    López, F.A.2    Heidelmeyer, C.F.3    Rossaint, R.4    Falke, K.J.5
  • 28
    • 0018487516 scopus 로고
    • Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
    • Heart Circ. Physiol. 5
    • Rabinovitch, M., W. Gamble, A. S. Nadas, O. S. Miettinen, and L. Reid. Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features. Am. J. Physiol. 236 (Heart Circ. Physiol. 5): H818-H827, 1979.
    • (1979) Am. J. Physiol. , vol.236
    • Rabinovitch, M.1    Gamble, W.2    Nadas, A.S.3    Miettinen, O.S.4    Reid, L.5
  • 29
    • 0027278227 scopus 로고
    • Inhaled nitric oxide: Selective pulmonary vasodilation in cardiac surgical patients
    • Rich, G. F., G. D. Murphy, C. M. Roos, and R. A. Johns. Inhaled nitric oxide: selective pulmonary vasodilation in cardiac surgical patients. Anesthesiology 78: 1028-1035, 1993.
    • (1993) Anesthesiology , vol.78 , pp. 1028-1035
    • Rich, G.F.1    Murphy, G.D.2    Roos, C.M.3    Johns, R.A.4
  • 30
    • 0028954471 scopus 로고
    • Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat
    • Roberts, J. D., C. T. Roberts, R, C. Jones, W. M. Zapol, and K. D. Bloch. Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat. Circ. Res. 76: 215-222, 1995.
    • (1995) Circ. Res. , vol.76 , pp. 215-222
    • Roberts, J.D.1    Roberts, C.T.2    Jones, R.C.3    Zapol, W.M.4    Bloch, K.D.5
  • 31
    • 0028340973 scopus 로고
    • Sites of vasodilation by inhaled nitric oxide vs. sodium nitroprusside in endothelin-constricted isolated rat lungs
    • Roos, C. M., G. F. Rich, D. R. Uncles, M. O. Daugherty, and D. U. Frank. Sites of vasodilation by inhaled nitric oxide vs. sodium nitroprusside in endothelin-constricted isolated rat lungs. J. Appl. Physiol. 77: 51-57, 1994.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 51-57
    • Roos, C.M.1    Rich, G.F.2    Uncles, D.R.3    Daugherty, M.O.4    Frank, D.U.5
  • 33
    • 0028011050 scopus 로고
    • Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS
    • Rovira, I., T. Y. Chen, M. Winkler, N. Kawai, K. D. Bloch, and W. M. Zapol. Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS. J. Appl. Physiol. 76: 345-355, 1994.
    • (1994) J. Appl. Physiol. , vol.76 , pp. 345-355
    • Rovira, I.1    Chen, T.Y.2    Winkler, M.3    Kawai, N.4    Bloch, K.D.5    Zapol, W.M.6
  • 34
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa, W. C., K. Pritchard, N. Seyedi, J. Wang, and T. H. Hintze. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res. 74: 349-353, 1994.
    • (1994) Circ. Res. , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 35
    • 0021256431 scopus 로고
    • Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists
    • Stanbrook, H. S., K. G. Morris, and I. F. McMurtry. Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists. Am. Rev. Respir. Dis. 130: 81-85, 1984.
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 81-85
    • Stanbrook, H.S.1    Morris, K.G.2    McMurtry, I.F.3
  • 36
    • 0027953809 scopus 로고
    • Homologous and heterologous desensitization of a guanylyl cyclase-linked nitric oxide receptor in cultured rat medullary interstitial cells
    • Ujiie, K., L. Hogarth, R. Danziger, J. G. Drewett, P. S. T. Yuen, I. H. Pang, and R. A. Star. Homologous and heterologous desensitization of a guanylyl cyclase-linked nitric oxide receptor in cultured rat medullary interstitial cells. J. Pharmacol. Exp. Ther. 270: 761-767, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 761-767
    • Ujiie, K.1    Hogarth, L.2    Danziger, R.3    Drewett, J.G.4    Yuen, P.S.T.5    Pang, I.H.6    Star, R.A.7
  • 37
    • 0028608979 scopus 로고
    • Distribution of NOS in normoxic vs. hypoxic rat lung: Upregulation of NOS by chronic hypoxia
    • Lung Cell. Mol. Physiol. 11
    • Xue, C., A. Rengasamy, T. D. Le Cras, P. A. Koberna, G. C. Dailey, and R. A. Johns. Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation of NOS by chronic hypoxia. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L667-L678, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Xue, C.1    Rengasamy, A.2    Le Cras, T.D.3    Koberna, P.A.4    Dailey, G.C.5    Johns, R.A.6
  • 38
    • 0028000349 scopus 로고
    • Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells
    • Yang, W., J. Ando, R. Korenaga, T. Toyo-oka, and A. Kamiya. Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells. Biochem. Biophys. Res. Commun. 203: 1160-1167, 1994.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1160-1167
    • Yang, W.1    Ando, J.2    Korenaga, R.3    Toyo-oka, T.4    Kamiya, A.5


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