Sensitization of TNF-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines

Cytokine

Volumn 10, Issue 6, 1998, Pages 423-431

  Penning, Louis C ^a,c   Schipper, Raymond G ^b   Vercammen, Dominique ^a   Verhofstad, Albert A J ^b   Denecker, Trui ^a   Beyaert, Rudi ^a   Vandenabeele, Peter ^a  

^a GHENT UNIVERSITY   (Belgium)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

APO 1; Apoptosis; Fas; Ornithine decarboxylase; Polyamine; Tumour necrosis factor

Indexed keywords

4 AMIDINO 1 INDANONE 2' AMIDINOHYDRAZONE; MITOGUAZONE; NORSPERMINE; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HISTIOCYTE; HUMAN; HUMAN CELL; HYBRIDOMA; MOUSE; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; RAT; RHABDOMYOSARCOMA; T LYMPHOCYTE; TUMOR CELL CULTURE; UTERINE CERVIX CARCINOMA;

EID: 0032101936     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1997.0310     Document Type: Article

References (52)

1. 1. Martins LM, Earnshaw WC (1997) Apoptosis: alive and kicking in 1977. Trends Cell Biol 7:111-114.
2. 2. Nagata, S (1997) Apoptosis by death factor. Cell 88:355-356.
3. 3. Beyaert R, Fiers W (1994) Molecular mechanisms of tumor necrosis factor-induced cytotoxicity; what we do understand and what we do not. FEBS Lett 340:9-16.
4. 4. Smith CA, Farrah T, Goodwin RG (1994) The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and cell death. Cell 76:959-962.
5. 5. Vandenabeele P, Declerq W, Beyaert R, Fiers W (1995) Two tumor necrosis factor receptors: structure and function. Trends Cell Biol 5:392-399.
6. 6. Tartaglia LA, Pennica D, Goeddel DV (1993) Ligand passing the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J Biol Chem 268:18542-18548.
7. 7. Vandenabeele P, Declerq W, Vercammen D, Van de Craen M, Grooten J, Loetscher H, Brockhaus M, Lesslauer W, Fiers W (1992) Functional characterization of the tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma. J Exp Med 176:1015-1024.
8. 8. Van Ostade X, Tavernier J, Prange T, Fiers W (1991) Localization of the active site of human tumor necrosis factor (hTNF) by mutational analysis. EMBO J 10:827-836.
9. 9. Declercq W, Vandenabeele P, Fiers W (1995) Dimerization of chymeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain. Cytokine 7:701-709.
10. 10. Fiers W, Beyaert R, Boone E, Cornelis S, Declercq W, Decoster E, Denecker G, Depuydt B, De Valck D, De Wilde G, Goossens V, Grooten J, Haegeman G, Heyninck K, Penning L, Plaisance S, Vancompernolle K, Van Criekinge W, Vandenabeele P, Vanden Berghe W, Van de Craen M, Vandevoorde V, Vercammen D (1996) TNF-induced intracellular signalling leading to gene induction or to cytotoxicity by necrosis or by apoptosis. J Inflamm 47:67-75.
11. 11. Heller RA, Kroenke M (1994) Tumor necrosis factor receptor-mediated signaling pathways. J Cell Biol 126:5-9.
12. 12. Schulze-Osthoff K (1994) The Fas/APO-1 receptor and its deadly ligand. Trends Cell Biol 4:421-426.
13. 13. Enari M, Hug H, Nagata S (1995) Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78-81.
14. 14. Miura M, Friedlander RM, Yuan J (1995) Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive pathway. Proc Natl Acad Sci USA 92:8318-8320.
15. 15. Los M, Van de Craen M, Penning LC, Schenk H, Westendorp H, Baeuerle PA, Droege WA, Krammer PH, Fiers W, Schulze-Osthoff K (1995) Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81-83.
16. 16. Tewari M, Dixit VM (1995) Fas- and TNF-induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 270:3255-3260.
17. 17. Schulze-Osthoff K, Krammer PH, Droege W (1994) Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. EMBO J 13:4587-4596.
18. 18. Packham G, Cleveland JL (1994) Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis. Mol Cell Biol 14:5741-5747.
19. 19. Jaenicke RU, Lee FHH, Porter AG (1994) Nuclear c-myc plays an important role in the cytotoxicity of tumor necrosis factor alpha in tumor cells. Mol Cell Biol 14:5661-5670.
20. 20. Klefstrom J, Vaestrik I, Saksela E, Valle J, Eilers M, Alitalo K (1994) c-Myc induces cellular susceptibility to the cytotoxic action of TNFα. EMBO J 13:5442-5450.
21. 21. Hayashi S, Murakami Y (1995) Rapid and regulated degradation of ODC. Biochem J 306:1-10.
22. 22. Auvinen M, Paasinen A, Andersson LC, Hoelttae E (1992) Ornithine decarboxylase activity is critical for cell transformation. Nature 360:355-358.
23. 23. Tamori A, Nishiguchi S, Kuroki T, Koh N, Kobayashi K, Yano Y, Otani S (1995) Point mutation of ornithine decarboxylase gene in human hepatocellular carcinoma. Cancer Res 55:3500-3503.
24. 24. Regenass U, Mett H, Stanek J, Mueller M, Kramer D, Porter CW (1994) CGP48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity. Cancer Res 54:3210-3217.
25. 25. Endo Y, Matsushima K, Onozaki K, Oppenheim JJ (1988) Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor. J Immunol 141:2342-2348.
26. 26. Donato NJ, Rotbein J, Rosenblum MG (1991) Tumor necrosis factor stimulates ornithine decarboxylase activity in human fibroblasts and tumor target cells. J Cell Biochem 46:69-77.
27. 27. Grassilli E, Desiderio MA, Bellesia E, Salomoni P, Benatti F, Franceschi C (1995) Is polyamine decrease a common feature of apoptosis? Evidence from gamma-rays and heat shock-induced cell death. Biochem Biophys Res Commun 216:708-714.
28. 28. Desiderio MA, Grassilli E, Bellesia E, Salomoni P, Franceschi C (1995) Involvement of ornithine decarboxylase and polyamines in glucocorticoid-induced apoptosis of rat thymocytes. Cell Growth Diff 6:505-513.
29. 29. Schipper RG, Otten AA, Rutten RG, Lange WP, Schalken JA, Verhofstad AAJ (1995) Role of polyamines in programmed cell death in prostatic cancer cells. Urol Res 23:249.
30. 30. Brune B, Hartzell P, Nicotera P, Orrenius S (1991) Spermine prevents endonuclease activation and apoptosis in thymocytes. Exp Cell Res 195:323-329.
31. 31. Gilad GM, Gilad VH (1992) Polyamines in neurotrauma. Ubiquitous molecules in search for a function. Biochem Pharmacol 44:401-407.
32. 32. Poulin R, Pelletier G, Pegg AE (1995) Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells. Biochem J 311:723-727.
33. 33. Tobias KE, Kahana C (1995) Exposure to ornithine results in excessive accumalation of putrescine and apoptotic cell death in ornithine decarboxylase overproducing mouse myeloma cells. Cell Growth Diff 6:1279-1285.
34. 34. Parchment RE (1993) The implications of a unified theory of programmed cell death, polyamines, oxyradicals and histogenesis in the embryo. Int J Dev Biol 37:75-83.
35. 35. Bolkenius FN, Bey P, Seiler N (1985) Specific inhibition of polyamine oxidase in vivo is a method for the elucidation of its physiological role. Biochim Biophys Acta 838:69-76.
36. 36. Snyder RD, Vogelpohl SJ, Baldwin BL, Deaton ED, Bade E, Carter JH (1996) Apparent inhibition of apoptosis by polyamines and aminothiols in DNA fragmentation assays is artificial. Cell Death Diff 3:323-330.
37. 37. Brooks WH (1995) Polyamine involvement in the cell cycle, apoptosis, and autoimmunity. Medical Hypotheses 44:331-338.
38. 38. Basu HS, Smirnov IV, Peng HF, Tiffany K, Jackson V (1997) Effects of spermine and its cytotoxic analogs on nucleosome formation on topologically stressed DNA in vitro. Eur J Biochem 243:247-258.
39. 39. Lopati AN, Makhina EN, Nichols CG (1994) Potassium channels block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature 372:366-369.
40. + channels. Science 266:1068-1072.
41. + channels by intracellular spermine. Cell 80:149-154.
42. 42. Forsythe ID (1995) A physiological function for polyamines? Current Biology 5:1248-1251.
43. 43. Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X (1997) Prevention of apoptosis by bcl-2: release of cytochrome c from mitochondria blocked. Science 275:1129-1132.
44. 44. Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis. Science 275:1132-1136.
45. 45. Bergeron RJ, Neims AH, McManis JS, Hawthorne TR, Bortell R, Ingeno MJ (1988) Synthetic polyamine analogues as antineoplastics. J Med Chem 32:1183-1190.
46. 46. Tavernier J, Franssen L, Maremout A, Van der Heyden J, Mueller J, Ruysschaert MR, Van Vliet A, Bauden R, Fiers W (1987) Isolation and expression of the genes coding for mouse and human tumor necrosis factor (TNF) and biological properties of recombinant TNF. In Webb DR, Goeddel DV (eds), Lymphokines, Vol. 13. Academic Press, Orlando, FL, pp. 181-198.
47. 47. Conzelmann A, Corthésy P, Cianfriglia M, Silva A, Nabholz M (1982) Hybrids between rat lymphoma and mouse T cells with inducible cytolytic activity. Nature 298:170-172.
48. 48. Vandenabeele P, Declercq W, Vanhaesebroeck B, Grooten J, Fiers W (1995) Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells. J Immunol 154:2904-2913.
49. 49. Seely JE, Pegg AE (1983) Ornithine decarboxylase (mouse kidney) In Tabor H, Tabor CW (eds). Methods in Enzymology, Vol. 94. Academic Press, London pp. 158-161.
50. 50. Kirschbaum J, Luckas B (1994) Precolumn derivatization of biogenic amines and amino acids with 9-fluoronylmethyl chloroformate and heptylamine. J Chromatogr 661:193-199.
51. 51. Suffys P, Beyaert R, Van Roy F, Fiers W (1987) Involvement of a serine protease in tumor-necrosis-factor-mediated cytotoxicity. Eur J Biochem 178:257-265.
52. 52. Vandenabeele P, Guisez Y, Declercq W, Bauw G, Vanderkerckhove J, Fiers W (1990) Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): differential induction of cytokines by human IL-1α and IL-18 and partial amino acid sequence of rat GM-CSF. Lymphokine Res 9:381-389.