Ataxia-telangiectasia and T-cell leukemias: No evidence for somatic ATM mutation in sporadic T-ALL or for hypermethylation of the ATM-NPAT/E14 bidirectional promoter in T-PLL

Cancer Research

Volumn 58, Issue 11, 1998, Pages 2293-2297

  Luo, Liping ^a   Lu, Feng Min ^a   Hart, Steve ^b   Foroni, Letizia ^b   Rabbani, Hodjattallah ^a   Hammarström, Lennart ^a   Webster, A David B ^b   Vořechovský, Igor ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ATAXIA TELANGIECTASIA; CHILD; CHROMOSOME 14; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA METHYLATION; DNA STRAND; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROLYMPHOCYTIC LEUKEMIA; PROMOTER REGION; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE;

ATAXIA TELANGIECTASIA; CELL CYCLE PROTEINS; DNA; DNA METHYLATION; DNA-BINDING PROTEINS; HUMANS; INVERSION, CHROMOSOME; LEUKEMIA, PROLYMPHOCYTIC; LEUKEMIA, T-CELL, ACUTE; LOSS OF HETEROZYGOSITY; MUTATION; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTEINS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0032101638     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., Ashkenazi, M., Pecker, I., Frydman, M., Harnik, R., Patanjali, S. R., Simmons, A., Clines, G. A., Sartiel, A., Gatti, R. A., Chessa, L., Sanal, O., Lavin, M. F., Jaspers, N. G. J., Taylor, A. M. R., Arlett, C. F., Miki, T., Weissman, S. M., Lovett, M., Collins, F. S., and Shiloh, Y. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science (Washington DC), 268: 1749-1753, 1995.
2. Savitsky, K., Sfez, S., Tagle, D. A., Ziv, Y., Sartiel, A., Collins, F. S., Shiloh, Y., and Rotman, G. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum. Mol. Genet., 4: 2025-2032, 1995.
3. Gatti, R. A., Berkel, I., Boder, E., Braedtd, G., Charmley, P., Concannon, P., Ersoy, F., Foroud, T., Jaspers, N. G. J., Lange, K., Lathrop, M. G., Leppert, M., Nakamura, Y., O'Connel, P., Paterson, M., Salser, W., Sanal, O., Silver, J., Sparkes, R. S., Susi, E., Weeks, D. E., Wei, S., White, R., and Yoder, F. Localization of an ataxiatelangiectasia gene to chromosome 11q22-q23. Nature (Lond.), 336: 577-580, 1988.
4. Taylor, A. M. R., Metcalfe, J. A., Thick, J., and Mak, Y-F. Leukemia and lymphoma in ataxia telangiectasia. Blood, 87: 423-438, 1996.
5. Hecht, F., Koler, R. D., Rigas, D. A., Dahnke, G. S., Case, M. P., Tisdale, V., and Miller, R. W. Leukaemia and lymphocytes in ataxia-telangiectasia. Lancet, 2: 1193, 1966.
6. Galton, D. A. G. Prolymphocytic leukaemia. Br. J. Haematol., 27: 7-23, 1974.
7. Brito-Babapulle, V., and Catovsky, D. Inversions and tandem translocations involving chromosome 14q11 and 14q32 in T-cell prolymphocytic leukemia and T-cell leukemias in patients with ataxia-telangiectasia. Cancer Genet. Cytogenet., 55: 1-9, 1991.
8. Matutes, E., Brito-Babapulle, V., Swansbury, J., Ellis, J., Morilla, R., Dearden, C., Sempere, A., and Catovsky, D. Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia. Blood, 78: 3269-3274, 1991.
9. Taylor, A. M. R., and Butterworth, S. V. Clonal evolution of T-cell chronic lymphocytic leukemia in a patient with ataxia telangiectasia. Int. J. Cancer, 37: 511-516, 1986.
10. Russo, G., Isobe, M., Gaiti, R., Finan, J., Batuman, O., Huebner, K., Nowell, P. C., and Croce, C. M. Molecular analysis of a t(14;14) translocation in leukemic T-cell of an ataxia telangiectasia patient. Proc. Natl. Acad. Sci. USA, 86: 602-606, 1989.
11. Vořechovský, I., Rasio, D., Luo, L., Monaco, C., Hammarström, L., Webster, A. D. B., Zaloudik, J., Barbanti-Brodano, G., James, M., Russo, G., Croce, C. M., and Negrini, M. The ATM gene and susceptibility to breast cancer: analysis of 38 breast tumors reveals no evidence for mutation. Cancer Res., 56: 2726-2732, 1996.
12. Vořechovský, I., Luo, L., Prudente, S., Chessa, L., Russo, G., Kanariou, M., James, M., Negrini, M., Webster, A. D. B., and Hammarström, L. Exon-scanning mutation analysis of the ATM gene in patients with ataxia-telangiectasia. Eur. J. Hum. Genet., 4: 352-355, 1996.
13. Vořechovský, I., Luo, L., Dyer, M. J. S., Catovsky, D., Amlot, P. L., Yaxley, J. C., Foroni, L., Hammarström, L., Webster, A. D. B., and Yuille, M. A. R. Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia. Nat. Genet., 17: 96-99, 1997.
14. Stilgenbauer, S., Schaffner, C., Litterst, A., Liebisch, P., Gilad, S., Bar-Shira, A., James, M. R., Lichter, P., and Döhner, H. Biallelic mutations in the ATM gene in T-prolymphocytic leukemia. Nat. Med., 3: 1155-1159, 1997.
15. Yuille, M. R., Coignet, L. J. A., Abraham, S. M., Yaqub, F., Luo, L., Matutes, E., Brito-Babapulle, V., Vořechovský, I., Dyer, M. J. S., and Catovsky, D. ATM is usually rearranged in T-cell prolymphocytic leukemia. Oncogene, 16: 789-796, 1998.
16. Stoppa-Lyonnet, D., Soulier, J., Lauge, A. , Dastot, H., Garand, R., Sigaux, F., and Stern, M-H. Inactivation of the ATM gene in T-cell prolymphocytic leukemia. Blood. 91: 1-8, 1998.
17. Jones, P. A. DNA methylation errors and cancer. Cancer Res., 56: 2463-2467, 1996.
18. Greger, V., Passarge, E., Höpping, W., Messmer, E., and Horsthemke, B. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet., 83: 155-158, 1989.
19. Stirzaker, C., Millar, D. S., Paul, C. L., Warnecke, P. M., Harrison, J., ,Vincent, P. C., Frommer, M., and Clark, S. J. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res., 57: 2229-2237, 1997.
20. Byrd, P. J., Cooper, P. R., Stankovic, T., Kullar, H. S., Watts, G. D. J., Robinson, P. J., and Taylor, A. M. R. A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies. Hum. Mol. Genet., 5: 1785-1791, 1996.
21. Imai, T., Yamauchi, M., Seki, N., Sugawara, T., Saito, T., Matsuda, Y., Ito, H., Nagase, T., Nomura, N., and Hori, T. Identification and characterization of a new gene physically linked to the ATM gene. Genome Res., 6: 439-447, 1996.
22. Janossy, G., and Campana, D. Monoclonal antibodies in the diagnosis of acute leukemia. The Leukemic Cell. In: D. Catovsky (ed.), Methods in Haematology, pp. 168-195. Churchill Livingstone, 1991.
23. Negrini, M., Rasio, D., Hampton, G. M., Sabbioni, S., Rattan, S., Carter, S. L., Rosenberg, A. L., Schwartz, G. F., Shiloh, Y., Cavenee, W. K., and Croce, C. M. Definition and refinement of chromosome 11 regions of LOH of breast cancer: identification of a new region at 11q23-q24. Cancer Res., 55: 3003-3007, 1995.
24. Frommer, M., McDonald, L. E., Millar, D. S., Collis, C. M., Watt, F., Grigg, G. W., Molloy, P. L., and Paul, C. L. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. USA, 89: 1827-1831, 1992.
25. Clark, S. J., Harrison, J., Paul, C. L., and Frommer, M. High-sensitivity mapping of methylated cytosines. Nucleic Acids Res., 22: 2990-2997, 1994.
26. Zeschnigk, M., Schmitz, B., Dittrich, B., Buiting, K., Horsthemke, B., and Doerfler, W. Imprinted segments in the human genome: different DNA methylation patterns in the Prader-Willi/Angelman syndrome region as determined by the genomic sequencing method. Hum. Mol. Genet., 6: 387-395, 1997.
27. Stöger, R., Kajimura, T. M., Brown, W. T., and Laird, C. D. Epigenetic variation illustrated by DNA methylation patterns of the fragile-X gene FMR1. Hum. Mol. Genet., 6: 1791-1801, 1997.
28. Warnecke, P. M., Stirzaker, C., Melki, J. R., Millar, D. S., Paul, C. L., and Clark, S. J. Detection and measurement of PCR bias in quantitative methylation analysis of bisulfite-treated DNA. Nucleic Acids Res., 25: 4422-4426, 1997.
29. Herman, J. G., Graff, J. R., Myöhänen, S., Nelkin, B. D., and Baylin, S. B. Methylation-specific PCR. A novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA, 93: 9821-9826, 1996.
30. Hsieh, C-L. Stability of patch methylation and its impact in regions of transcriptional initiation and elongation. Mol. Cell. Biol., 17: 5897-5904, 1997.