Novel p53 tumour suppressor mutations in cases of spindle cell sarcoma, pleomorphic sarcoma and fibrosarcoma in cats

Veterinary Research Communications

Volumn 22, Issue 4, 1998, Pages 249-255

  Mayr, B ^a   Reifinger, M ^a   Alton, K ^a   Schaffner, G ^b  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Cat; Mutation; p53 gene; Sarcoma; Tumour

Indexed keywords

FELIDAE; FELIS CATUS;

DNA;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL DISEASE; ARTICLE; BLADDER TUMOR; CAT; CAT DISEASE; CHEMISTRY; DNA SEQUENCE; FEMALE; FIBROSARCOMA; GENE DELETION; GENETICS; MALE; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; POLYMERASE CHAIN REACTION; SARCOMA; SKIN TUMOR; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CAT DISEASES; CATS; DNA, NEOPLASM; FEMALE; FIBROSARCOMA; GENE DELETION; GENES, P53; MALE; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; SARCOMA; SEQUENCE ANALYSIS, DNA; SKIN NEOPLASMS; URINARY BLADDER NEOPLASMS;

EID: 0032086494     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006091215330     Document Type: Article

References (14)

1. Breau, R.L. and Clayman, G.L., 1996. Gene therapy for head and neck cancer. Current Opinion in Oncology, 8, 227-231
2. De Vries, E.M.G., Ricke, D.O., De Vries, T.N., Hartmann, A., Blaszyk, H., Liao, D., Soussi, T., Kovach, J.S. and Sommer, S.S., 1996. Database of mutations in the p53 and APC tumor suppressor genes designed to facilitate molecular epidemiological analyses. Human Mutation, 7, 202-213
3. Hollstein, M., Shomer, B., Greenblatt, M., Soussi, T., Hovig, E., Montesano, R. and Harris, C.C., 1996. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Research, 24, 141-146
4. Levine, A.J., Momand, J. and Finlay, C.A., 1991. The p53 tumour suppressor gene. Nature, 351, 453-456
5. Mayr, B., Heczko, U., Schellander, K., Schleger, W. and Reifinger, M., 1993. Sequence of an exon of the feline p53 gene - mutation in a lymphosarcoma. British Veterinary Journal, 149, 387-390
6. Mayr, B., Schaffner, G., Kurzbauer, R., Schneider, A., Reifinger, M. and Loupal, G., 1995a. Mutations in tumour suppressor gene p53 in two feline fibrosarcomas. British Veterinary Journal, 151, 707-713
7. Mayr, B., Schaffner, G., Kurzbauer, R., Reifinger, M. and Schellander, K., 1995b. Sequence of an exon of tumour suppressor p53 gene - a comparative study in domestic animals. Mutation in a feline solid mammary carcinoma. British Veterinary Journal, 151, 325-329
8. Mayr, B., Reifinger, M. and Loupal, G., 1998. Polymorphisms in feline tumour suppressor gene p53. Mutations in an osteosarcoma and a mammary carcinoma. Veterinary Journal, 155, 103-106
9. Müllenbach, J.P., Lagoda, L. and Welter, C., 1989. An efficient salt-chloroform extraction of DNA blood and tissues. Trends in Genetics, 5, 391
10. Okuda, M., Umeda, A., Sakai, T., Ohashi, T., Momoi, Y., Youn, H. Y., Watari, T., Goitsuka, R., Tsujimoto, H. and Hasegawa, A., 1994. Cloning of feline p53 tumor-suppressor gene and its aberration in hematopoietic tumor. International Journal of Cancer, 58, 602-607
11. Roth, J.A., Nguyen, D., Lawrence, D.D., Kemp, B.L., Carrasco, C.H., Ferson, D.Z., Hong, W.K., Komaki, R., Lee, J.J., Nesbitt, J.C., Pisters, K.M., Putnam, J.B., Schea, R., Shin, D.M., Walsh, G.L., Dolormente, M.M., Han, C.I., Martin, F.D., Yen, N., Xu, K., Stephens, L.C., McDonell, T.J., Mukhopadhyay, T. and Cai, D., 1996. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer (see comments). Nature Medicine, 2, 974-975
12. Soussi, T., 1995. The p53 tumour suppressor gene: from molecular biology to clinical investigation. In: J.K. Cowell (ed.), Molecular Genetics of Cancer, (Bios Scientific Publishers), 135-178
13. Soussi, T., De Fromentel, C. and May, P., 1990. Structural aspects of the p53 protein in relation to gene evolution. Oncogene, 5, 945-952
14. Vogelstein, B. and Kinzler, K.W., 1992. p53 function and disfunction. Cell, 70, 523-526