Database of mutations in the p53 and APC tumor suppressor genes designed to facilitate molecular epidemiological analyses

Human Mutation

Volumn 7, Issue 3, 1996, Pages 202-213

  De Vries, Ellen M G ^a   Ricke, Darrell O ^a   De Vries, Thomas N ^d   Hartmann, Arndt ^a   Blaszyk, Hagen ^a   Liao, Dongzhou ^d   Soussi, Thierry ^b   Kovach, John S ^a,c   Sommer, Steve S ^a  

^a MAYO CLINIC   (United States)

^b U d'Oncol Genet Molec   (France)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^d NONE

Author keywords

APC gene; Database; Epidemiological analyses; p53 gene

Indexed keywords

ARTICLE; CANCER; CARCINOGENESIS; DATA BASE; EPIDEMIOLOGICAL DATA; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MOLECULAR GENETICS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

COMPUTER COMMUNICATION NETWORKS; DATABASES, FACTUAL; EPIDEMIOLOGY, MOLECULAR; GENES, APC; GENES, P53; GERM-LINE MUTATION; HUMANS; MUTATION; NEOPLASMS; POLYMORPHISM, GENETIC;

EID: 0029984305     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1004(1996)7:3<202::AID-HUMU4>3.0.CO;2-C     Document Type: Article

References (8)

1. Blaszyk H, Vaughn CB, Hartmann A, McGovern RM, Schroeder JJ, Cunningham J, Schaid D, Sommer SS, Kovach JS (1994) Novel pattern of p53 gene mutations in an American black cohort with high mortality from breast cancer. Lancet 343: 1195-1197.
2. Brash DE, Rudolph JA, Simon JA, Lin A, McKeanna GJ, Baden HP, Halperin AJ, Poten J (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88:10124-10128.
3. Bressac B, Kew M, Wands J, Ozturk M (1991) Selective G to T mutations of p53 in hepatocellular carcinoma from Southern Africa. Nature 350:429-431.
4. Cariello NF, Cui L, Beroud C, Soussi T (1994a) Database and software for the analysis of mutations in the human p53 gene. Cancer Res 54:4454-4460.
5. Cariello NF, Piegorsch WW, Adams WT, Skopek TR (1994b) Computer program for the analysis of mutational spectra: application to p53 mutations. Carcinogenesis 15:2281-2285.
6. Chiba I, Takahashi T, Nau MM, D'Amico D, Curiel DT, Mitsudomi T, Buchhagen DL, Carbone D, Piantadosi S, Koga H, Reissman PT, Slamon DJ, Holmes EC, Minna JD (1990) Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancers. Oncogene 5:1063-1610.
7. Coles C, Condi A, Chetty U, Steel CM, Evans J, Prosser J (1992) p53 mutations in breast cancer. Cancer Res 52:5291-5298.
8. Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.