Immunohistochemical detection of sex steroid receptors, cyclins, and cyclin-dependent kinases in the normal and neoplastic squamous epithelia of the uterine cervix

Cancer

Volumn 82, Issue 9, 1998, Pages 1709-1719

  Kanai, Makoto ^a   Shiozawa, Tanri ^a   Xin, Lu ^a   Nikaido, Toshio ^a   Fujii, Shingo ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cervical carcinoma; Cyclin; Cyclin dependent kinase; Ki 67; Steroid receptor

Indexed keywords

CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN E; CYCLINE; ESTROGEN RECEPTOR; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; PROTEIN P53; STEROID RECEPTOR;

ADULT; AGED; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; SQUAMOUS EPITHELIUM; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CERVIX UTERI; CYCLIN-DEPENDENT KINASES; CYCLINS; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MIDDLE AGED; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; REFERENCE VALUES; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 0032080883     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19980501)82:9<1709::AID-CNCR18>3.0.CO;2-8     Document Type: Article

References (50)

1. Sanborn BM, Kuo HS, Held B. Estrogen and progesterone binding site concentrations in human endometrium and cervix throughout the menstrual cycle and in tissue from women taking oral contraceptives. J Steroid Biochem Mol Biol 1978;9:951-5.
2. Cao ZY, Eppenberger U, Roos W, Torhorst J, Almendral A. Cytosol estrogen and progesterone receptor levels measured in normal and pathological tissue of endometrium, endocervical mucosa, and cervical vaginal portion. Arch Gynecol Obstet 1983;233:109-19.
3. Ferenczy A, Wright TC. Anatomy and histology of the cervix. In: Blaustein's pathology of the female genital tract. 4th edition. New York: Springer-Verlag, 1994.
4. Reiner A, Neumeister B, Spona J, Reiner G, Schemper M, Jakesz R. Immunocytochemical localization of estrogen and progesterone receptor, and prognosis in human primary breast cancer. Cancer Res 1990;50:7057-61.
5. Creasman WT. Prognostic significance of hormone receptors in endometrial cancer. Cancer 1993;71:1467-70.
6. Li SF, Shiozawa T, Nakayama K, Nikaido T, Fujii S. Stepwise abnormality of sex steroid hormone receptors, tumor suppressor gene products (p53 and Rb), and cyclin E in uterine endometrioid carcinoma. Cancer 1996;77:321-9.
7. Sherr CJ. Mammalian G1 cyclins. Cell 1993;73:1059-65.
8. Nurse P. Ordering S phase and M phase in the cell cycle. Cell 1994;79:547-50.
9. Sherr CJ. G1 phase progression: cyclin on cue. Cell 1994;79:551-5.
10. Hartwell LH, Kasten MB. Cell cycle control and cancer. Science 1994;266:1821-8.
11. Goodrich DW, Lee WH. Molecular characterization of the retinoblastoma susceptibility gene. Biochem Biophys Acta 1993;1155:43-61.
12. Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell 1992;70:523-6.
13. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1985;133:1710-5.
14. Shi S-R, Imam SA, Young L, Cote RJ, Taylor CR. Antigen retrieval immunohistochemistry under the influence of pH using monoclonal antibodies. J Histochem Cytochem 1995;43:193-201.
15. Ciocca DR, Puy LA, Fasoli LC. Study of estrogen receptor, progesterone receptor, and the estrogen-regulated Mr 24.000 protein in patients with carcinomas of the endometrium and cervix. Cancer Res 1989;49:4298-304.
16. Cano A, Monmeneu R, Serra V, Marzo C, Rivera J. Expression of estrogen receptors, progesterone receptors, and an estrogen receptor associated protein in the human cervix during the menstrual cycle and menopause. Fertil Steril 1990; 54:1058-64.
17. Nonogaki H, Fujii S, Konishi I, Nanbu Y, Ozaki S, Ishikawa Y, et al. Estrogen receptor localization in normal and neoplastic epithelium of the uterine cervix. Cancer 1990; 66:2620-7.
18. Konishi I, Fujii S, Nonogaki H, Nanbu Y, Iwai T, Takahide M. Immunohistochemical analysis of estrogen receptors, progesterone receptors, Ki-67 antigen, and human papillomavirus DNA in normal and neoplastic epithelium of the uterine cervix. Cancer 1991;68:1340-50.
19. Ciocca DR, Lo Castro G, Alonio LV, Cobo MF, Lotfi H, Teyssie A. Effect of human papillomavirus infection on estrogen receptor and heat shock protein hsp27 phenotype in human cervix and vagina. Int J Gynecol Pathol 1992;11:113-21.
20. Masood S, Rhatigan RM, Wilkinson EW, Barwick KW, Wilson WJ. Expression and prognostic significance of estrogen and progesterone receptors in adenocarcinoma of the uterine cervix. An immunohistochemical study. Cancer 1993; 72:511-8.
21. Robertson DI, Paslawski D, Duggan MA, Stuart GC, Nation JG. Estrogen and progesterone receptor, human papillomavirus, and DNA ploidy analysis in invasive carcinoma of the cervix in pregnancy. Am J Clin Pathol 1993;100:18-21.
22. Taylor CR, Shi SR, Chaiwun B, Young L, Imam SA, Cote RJ. Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and Ki-67 antigen revealed by antigen retrieval techniques. Hum Pathol 1994;25:263-70.
23. Raju GC. Expression of proliferating cell nuclear antigen in cervical neoplasia. Int J Gynecol Pathol 1994;13:337-41.
24. Keyomarsi K, Pardee AB. Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci USA 1993;90:1112-6.
25. Dulic V, Drullinger LF, Lees E, Reed SI, Stein GH. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci USA 1993;90:11034-8.
26. Sgambato A, Han EK, Zhou P, Schieren I, Weinstein IB. Overexpression of cyclin E in the HC11 mouse mammary epithelial cell line is associated with growth inhibition and increased expression of p27Kip1. Cancer Res 1996;56:1389-99.
27. Wang A, Yoshimi N, Suzui M, Yamauchi A, Tarao M, Mori H. Different expression patterns of cyclins A, D1 and E in human colorectal cancer. J Cancer Res Clin Oncol 1996;122:122-6.
28. Dutta A, Chandra R, Leiter LM, Lester S. Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. Proc Natl Acad Sci USA 1995;92:5386-90.
29. Ymamoto M, Yoshida M, Ono K, Fujita T, Ohtani-Fujita N, Sakai T, et al. Effect of tumor suppressors on cell cycle-regulatory genes: RB suppresses p34cdc2 expression and normal p53 suppresses cyclin A expression. Exp Cell Res 1994;210:94-101.
30. Guadagno TM, Ohtsubo M, Roberts JM, Assoian RK. A link between cyclin A expression and adhesion-dependent cell cycle progression. Science 1993;262:1572-5.
31. Nakano T, Oka K. Differential values of Ki-67 index and mitotic index of proliferating cell population. An assessment of cell cycle and prognosis in radiation therapy for cervical cancer. Cancer 1993;72:2401-8.
32. Volm M, Koomagi R, Mattern J, Stammler G. Cyclin A is associated with an unfavourable outcome in patients with non-small-cell lung carcinomas. Br J Cancer 1997;75:1774-8.
33. Gong J, Ardelt B, Traganos F, Darzynkiewicz Z. Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. Cancer Res 1994;54:4285-8.
34. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993;366:701-4.
35. el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
36. Livingstone LR, White A, Sprouse J, Livanos E, Jacks T, Tlsty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 1992;70:923-35.
37. Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Wahl GM. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992;70:937-48.
38. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993; 362:849-52.
39. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs K, Kim-Chi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991;352:345-7.
40. Akasofu M, Oda Y. Immunohistochemical detection of p53 in cervical epithelial lesions with or without infection of human papillomavirus types 16 and 18. Virchows Arch 1995;425:593-602.
41. Holm R, Skomedal H, Helland A, Kristensen G, Borresen AL, Nesland JM. Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri. J Pathol 1993;169:21-6.
42. Mittal KR, Lin O, Chan W, Goswami S, Demopoulos RI. Cervical squamous dysplasias and carcinomas with immunodetectable p53 frequently contain HPV. Gynecol Oncol 1995; 58:289-94.
43. ter Harmsel B, von Belkum A, Quint W, Pronk A, Kuijpers J, Ramaekers F, et al. p53 and human papilloma virus type 16 in cervical intraepithelial neoplasia and carcinoma. Int J Gynecol Pathol 1995;14:125-33.
44. Bosari S, Roncalli M, Viale G, Bossi P, Coggi G. p53 immunoreactivity in inflammatory and neoplastic diseases of the uterine cervix. J Pathol 1993;169:425-30.
45. Finlay CA, Hinds PW, Levine AJ. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989; 57:1083-93.
46. Vojtesek B, Bartek J, Midgley CA, Lane DP. An immunochemical analysis of the human nuclear phosphoprotein p53. J Immunol Methods 1992;151:237-44.
47. Fujita M, Inoue M, Tanizawa O, Iwamoto S, Enomoto T. Alteration of the p53 gene in human primary cervical carcinoma with and without human papillomavirus infection. Cancer Res 1992;52:5323-8.
48. Busby-Earle RM, Steel CM, Williams AR, Cohen B, Bird CC. p53 mutations in cervical carcinogenesis-low frequency and lack of correlation with human papillomavirus status. Br J Cancer 1994;69:732-7.
49. Hamada K, Alemany R, Zhang WW, Hittelman WN, Lotan R, Roth JA, et al. Adenovirus-mediated transfer of a wild-type p53 gene and induction of apoptosis in cervical cancer. Cancer Res 1996;56:3047-54.
50. Isacson C, Kessis TD, Hedrick L, Cho KR. Both cell proliferation and apoptosis increase with lesion grade in cervical neoplasia but do not correlate with human papillomavirus type. Cancer Res 1996;56:669-74.