Both cell proliferation and apoptosis increase with lesion grade in cervical neoplasia but do not correlate with human papillomavirus type

Cancer Research

Volumn 56, Issue 4, 1996, Pages 669-674

  Isacson, Christina ^a   Kessis, Theodore D ^a   Hedrick, Lora ^a   Cho, Kathleen R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; TUMOR ANTIGEN;

APOPTOSIS; ARTICLE; CANCER GRADING; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; NUCLEOSOME; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA; VERRUCA VULGARIS; WART VIRUS;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL DIVISION; CERVIX UTERI; CONDYLOMATA ACUMINATA; DNA NUCLEOTIDYLEXOTRANSFERASE; EPITHELIAL CELLS; EPITHELIUM; FEMALE; HUMANS; KI-67 ANTIGEN; KINETICS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; UTERINE CERVICAL NEOPLASMS;

EID: 0030041915     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Ferenczy, A., and Wright, T. C. Anatomy and histology of the cervix. In: R. J. Kurman (ed.), Blaustein's Pathology of the Female Genital Tract, pp. pp. 185-201. New York: Springer-Verlag, 1994.
2. Bosch, F. X., Manos, M. M., Munoz, N., Sherman, M., Jansen, A. M., Peto, J., Schiffman, M. H., Moreno, V., Kurman, R., and Shah, K. V. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International Biological Study on Cervical Cancer (IBSCC) Study Group. J. Natl. Cancer Inst., 87: 796-802, 1995.
3. Schiffman, M. H., Bauer, H. M., Hoover, R. N., Glass, A. G., Cadell, D. M., Rush, B. B., Scott, D. R., Sherman, M. E., Kurman, R J , Wacholder, S., Stanton, C K., and Manos, M M Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J. Natl. Cancer Inst., 85: 958-964, 1993
4. Lorincz, A T , Temple, G. F., Kurman, R. J., Jenson, A. B., and Lancaster, W. D. Oncogenic association of specific human papillomavirus types with cervical neoplasia. J. Natl. Cancer Inst , 79: 671-677, 1987.
5. Lorincz, A. T., Reid, R., Jenson, A B , Greenberg, M. D , Lancaster, W., and Kurman, R. J. Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types. Obstet. Gynecol., 79: 328-337, 1992.
6. Demeter, L. M., Stoler, M. H., Broker, T R., and Chow, L T Induction of proliferating cell nuclear antigen in differentiated keratinocytes of human papillomavirus-infected lesions. Hum. Pathol., 25. 343-348, 1994.
7. Al-Saleh, W., Delvenne, P., Greimers, R , Fridman, V., Doyen, J., and Boniver, J. Assessment of Ki-67 antigen immunostaining in squamous intraepithelial lesions of the uterine cervix. Am J. Clin. Pathol., 104: 154-160, 1995.
8. Werness, B. A., Levine, A. J , and Howley, P. M. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (Washington DC), 248. 76-79, 1990.
9. Dyson, N., Howley, P , Munger, K , and Harlow, E. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (Washington DC), 243: 934-937, 1989.
10. Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L , Kimchi, A., and Oren, M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (Lond.), 352: 345-347, 1991.
11. Shaw, P., Bovey, R , Tardy, S., Sahli, R., Sordat, B., and Costa, J. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc. Natl. Acad Sci USA, 89: 4495-4499, 1992.
12. Symonds, H , Krall, L., Remington, L., Saenz-Robles, M., Lowe, S., Jacks, T., and Van Dyke, T. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell, 78: 703-711, 1994.
13. White, A. E., Livanos, E. M., and Tlsty, T. D. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes & Dev., 8: 666-677, 1994.
14. Howes, K. A , Ransom, N , Papermaster, D. S., Lasudry, J G., Albert, D. M , and Windle, J. J. Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes & Dev., 8: 1300-1310, 1994.
15. Pan, H , and Griep, A. E. Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes & Dev., 8: 1285-1299, 1994.
16. Lechner, M. S., and Laimins, L. A. Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J. Virol., 68: 4262-4273, 1994.
17. Crook, T., Fisher, C , Masterson, P. J , and Vousden, K. H. Modulation of transcriptional regulatory properties of p53 by HPV-E6. Oncogene, 9: 1225-1230, 1994.
18. Wright, T C., Kurman, R. J., and Ferenczy, A. Precancerous lesions of the cervix. In: R. J. Kurman (ed.), Blaustein's Pathology of the Female Genital Tract, pp 229-277. New York: Springer-Verlag, 1994.
19. Manos, M , Ting, Y., Wright, A., Broker, T , and Wolinsky, S The use of polymerase chain reaction amplification for the detection of genital human papillomaviruses Molecular diagnostics of human cancer. In: Cancer Cells, pp. 209-214 Cold Spring Harbor, NY: Cold Spring Laboratory, 1989.
20. Greer, C. E., Peterson, S. L., Kiviat, N B., and Manos, M. M. PCR amplification from paraffin-embedded tissues: effects of fixative and fixation time Am. J. Clin. Pathol., 95. 117-124, 1991
21. 1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc. Natl. Acad. Sci. USA, 91: 5320-5324, 1994.
22. Scott, R. J , Hall, P. A , Haldane, J. S., van Noorden, S., Price, Y., Lane, D. P., and Wright, N. A. A comparison of immunohistochemical markers of cell proliferation with experimentally determined growth fraction. J. Pathol., 165: 173-178, 1991.
23. Cattoretti, G., Becker, M. H , Key, G , Duchrow, M., Schluter, C., Galle, J., and Gerdes, J. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol., 168: 357-363, 1992.
24. Kyprianou, N., and Isaacs, J T. Activation of programmed cell death in the rat ventral prostate after castration. Endocrinology, 122. 552-562, 1988
25. Rorke, E. A., and Jacobberger, J W. Transforming growth factor-β1 (TGF β1) enhances apoptosis in human papillomavirus type 16-immortalized human ectocervical epithelial cells. Exp. Cell. Res., 216: 65-72, 1995.
26. Wyllie, A. Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview Cancer Metastasis Rev., 11: 95-103, 1992.
27. Sarraf, C. E., and Bowen, I. D. Proportions of mitotic and apoptotic cells in a range of untreated experimental tumours. Cell Tissue Kinet., 21: 45-49, 1988.
28. Columbano, A., Ledda-Columbano, G. M., Rao, P M., Rajalakshmi, S , and Sarma, D. S. Occurrence of cell death (apoptosis) in preneoplastic and neoplastic liver cells. a sequential study. Am. J. Pathol., 116: 441-446, 1984.
29. Aihara, M., Truong, L. D , Dunn, J. K., Wheeler, T. M., Scardino, P. T., and Thompson, T. C. Frequency of apoptotic bodies positively correlates with Gleason grade in prostate cancer Hum. Pathol., 25: 797-801, 1994
30. Berges, R. R , Vukanovic, J , Epstein, J. I., CarMichel, M., Cisek, L., Johnson, D. E., Veltri, R. W , Walsh, P C., and Isaacs, J. T. Implications of cell kinetic changes during the progression of human prostatic cancer Clin. Cancer Res., 1. 473-480, 1995.
31. El-Labban, N. G., and Osorio-Herrera, E. Apoptotic bodies and abnormally dividing epithelial cells in squamous cell carcinoma Histopathology, 10: 921-931, 1986
32. Stoler, M. H., Wolinsky, S. M., Whitbeck, A., Broker, T. R., and Chow, L. T Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes. Virology, 172: 331-340, 1989.
33. Stoler, M H., Rhodes, C. R., Whitbeck, A., Wolinsky, S M., Chow, L. T., and Broker, T. R Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum. Pathol., 23: 117-128, 1992
34. Bursch, W., Paffe, S., Putz, B., Barthel, G., and Schulte-Hermann, R. Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis (Lond.), 11: 847-853, 1990.
35. Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C., Hooper, M. L., and Wyllie, A. H. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature (Lond), 362: 849-852, 1993.
36. Berges, R. R., Furuya, Y., Remington, L , English, H. F., Jacks, T., and Isaacs, J. T. Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation. Proc. Natl. Acad. Sci. USA, 90. 8910-8914, 1993.
37. Xu, C., Meikrantz, W., Schlegel, R., and Sager, R. p53, p21, mitomycin, staurosporine, and ubiquitinylation: the human papilloma virus 16 E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage. Proc. Natl. Acad. Sci. USA, 92: 7829-7833, 1995.
38. Chen, J. J , Reid, C. E , Band, V , and Androphy, E. J. Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein. Science (Washington DC), 269. 529-531, 1995.